test research

Yes

No

No

• Cancer Research and Oncology
• Computational Biology and Bioinformatics
• Translational Medicine and Drug Discovery
• Molecular Genetics and Precision Medicine

B cells, bioinformatics, cancer genomics, cancer immunology, data integration, lung cancer, spatial profiling techniques, tumour microenvironment

Yes

Yes

Yes Snap frozen Brain tumour tissue/blood samples collected in 2000-2008. No longer actively banking.

No

• Cancer Research and Oncology
• Neuroscience and Neurodegenerative Diseases
• Translational Medicine and Drug Discovery
• Molecular Genetics and Precision Medicine

brain cancer, cancer, epigenomics, Genomics, neuro-oncology, neuropathology, oncology, pathology

No

No

No

• Cardiopulmonary and Vascular Medicine

chronic obstructive pulmonary disease (COPD), interstitial lung disease; cryobiopsy

Yes

Yes

No

• Cancer Research and Oncology
• Translational Medicine and Drug Discovery
• Molecular Genetics and Precision Medicine

acute lymphoblastic leukemia (ALL) pathogenesis, clinical flow cytometry and lymphoma tumor repository, high-throughput sequencing and gene editing technologies, NOTCH1 and oncogene research in T-ALL, tumor heterogeneity in B-cell lymphoma

Yes

Yes

COVID-19 biobank consisting of acute blood (serum and plasma) specimens from COVID-19 patients hospitalized the ICU during the first waves of the pandemic, as well as chronic specimens collected from patients who recovered from COVID-19 infections up to ~2 years post-infection. Some ICU samples have limited PBMCs.

Yes

The Wellington lab has a major interest in fluid biomarkers, and has the following resources available now on a collaborative basis: Quanterix HD-X (2 units), SP-X (1 unit) and Alamar NULISA Argo (1 unit).
Expected in 2025: Roche cobas e402 and Fujirebio Lumipulse G1200

• Neuroscience and Neurodegenerative Diseases

biomarkers, dementia, lipids, neurology, neurotrauma

Yes

Yes

I direct the BC Cancer Tumor tissue repository (biobank) and the BC Cancer Biobanking and Biospecimen services (biobank services). Details of these and several subcollections that are all open access and CTRNet registered and certified can be found on the Canadian Tissue Repository Network (CTRNet) national biobank locator https://biobanking.org/locator

No

• Cancer Research and Oncology
• Translational Medicine and Drug Discovery
• Molecular Genetics and Precision Medicine

biobanking, biomarkers, breast cancer, Molecular pathology

Yes

Yes

Bruce McManus Cardiovascular Biobank that has the largest collection of freshly collected failed hearts and valves in Canada: https://www.hli.ubc.ca/our-services/cardiovascular-tissue-registry/ PhenoCycler multiplex imaging platform: can image 3-50+ protein markers on one tissue section

No

• Cardiopulmonary and Vascular Medicine
• Translational Medicine and Drug Discovery
• Molecular Genetics and Precision Medicine

cardiovascular disease, drug repurposing, human tissue and blood biobank, in situ multiplex imaging, inflammation, transcriptomics

Yes

No

No

• Cancer Research and Oncology
• Infectious Diseases and Immunology

autoimmune disorders and adaptive immune responses, B cells, blood cancer, clonal precursor populations, disease dissemination, immune biology, lymphoma, preclinical models, tumor immunology,  functional genetics

No

No

No

• Infectious Diseases and Immunology
• Neuroscience and Neurodegenerative Diseases
• Cardiopulmonary and Vascular Medicine

allergic lung inflammation, cytokines, hepatitis. fibrosis, innate immunity, lymphocytes

Yes

Yes

No

• Cancer Research and Oncology
• Infectious Diseases and Immunology
• Translational Medicine and Drug Discovery
• Molecular Genetics and Precision Medicine

biomarker, cancer, cancer genomics, immunology, lymphoma, molecular genetics, outcome prediction, targeted therapy, tumor microenvironment

Maybe

No

No

• Cancer Research and Oncology
• Translational Medicine and Drug Discovery
• Molecular Genetics and Precision Medicine

and immunotherapy, biochemistry and proteomics, cell stress pathways, childhood cancers, childhood CNS tumors, childhood sarcomas, pediatric oncology, the tumor microenvironment

No

No

No

• Computational Biology and Bioinformatics
• Translational Medicine and Drug Discovery
• Molecular Genetics and Precision Medicine

Analytical validation Process, automation, Biomarker development and deployment, Data mining, Genomics, High throughput biological data management and analysis, Molecular pathology, optimization and reproducibility, Quality Control

Yes

Yes

We have frozen human lung tissue and inflated whole lungs from asthmatic, COPD, and healthy donners.

Yes

Myographs for in vitro smooth muscle experiments, measuring muscle force, shortening, power, and stiffness. Plethysmograph for whole lung experiments, measuring lung elastance and resistance. The plethysmograph can be placed in a CT scanner to measure structural changes in the lungs while monitoring the changes in lung mechanics.

• Cardiopulmonary and Vascular Medicine
• Translational Medicine and Drug Discovery
• Molecular Genetics and Precision Medicine

airway smooth muscle, and mechanopharmacology, asthma, lung mechanics, muscle mechanics, smooth muscle biochemistry

Yes

Yes

No

• Cancer Research and Oncology
• Translational Medicine and Drug Discovery
• Molecular Genetics and Precision Medicine

colorectal cancer, GI Pathology, Next-Generation Sequencing, pancreatic cancer

Maybe

No

No

• Cancer Research and Oncology
• Translational Medicine and Drug Discovery

translational research and basic research/cancer biology

Yes

No

No

• Cancer Research and Oncology
• Computational Biology and Bioinformatics
• Translational Medicine and Drug Discovery

bioinformatics, cancer, computational statistics, Genomics, machine learning, single cell omics

Yes

No

Yes

What I do have/utilize are several conventional and novel/risk variant models of inflammatory and chemical demyelinating/neurodegenerative MS preclinical models which includes tissues and samples which we use for biomarker evaluation compared to human tissues and samples which we obtain from collaborators/have ongoing collaborations for national studies (and a small set of our own, which we cannot make available at this time).

• Infectious Diseases and Immunology
• Neuroscience and Neurodegenerative Diseases

foundational or basic research, immunology, inflammation, multiple sclerosis, neurodegeneration, neuroimmunology, neuroinflammation, preclinical models of disease

Yes

No

Yes

Fully functional microbiology BSL-2 laboratory capable of culturing microorganisms

• Translational Medicine and Drug Discovery
• Molecular Genetics and Precision Medicine

laboratory education, microbiology, professional development, proficiency testing, quality, quality education, quality management, quality standards

Yes

Yes

Our lab focuses on designing a new computational method tailored to large-scale data analysis. We collaborate with the labs at BC Cancer to make single-cell data analysis accessible and robust.

Yes

GPU workstation and HPC clusters

• Cancer Research and Oncology
• Computational Biology and Bioinformatics
• Molecular Genetics and Precision Medicine

cancer genomics, causal inference, computational biology, high-dimensional data analysis, single-cell genomics

depends. My duties as MD/PhD program director force me onto a large number of committees, more than my bandwidth really allows. I can only sit on Pathology student committees if they are also in the MD/PhD program, as a few are.

Yes

I help manage the Bone & Soft Tissue biobank, as well as MAPcore which can provide access to tissue microarrays of most tissues and tumor types

Yes

equipment including immunohistochemistry autostainers, microscope slide scanners, nanoString prep station / digital analyzer / GeoMX digital spatial profiler, and a Zeiss axioscan https://mapcore.med.ubc.ca/equipment/

• Cancer Research and Oncology
• Translational Medicine and Drug Discovery
• Molecular Genetics and Precision Medicine

breast cancer, histopathology, molecular diagnostics, sarcoma

Yes

No

No

• Cancer Research and Oncology
• Computational Biology and Bioinformatics
• Translational Medicine and Drug Discovery

3D tissue models, DNA repair mechanism, drug discovery, electron transport chain, extravascular drug distribution, FLASH radiotherapy, MRI applications in oncology, tumor microenvironment

Yes

Yes

No

• Neuroscience and Neurodegenerative Diseases
• Molecular Genetics and Precision Medicine

dementia, frontotemporal dementia, molecular genetics, neurodegenerative disease, proteinopathy,  amyotrophic lateral sclerosis

Yes

Yes

No

• Cancer Research and Oncology
• Infectious Diseases and Immunology
• Neuroscience and Neurodegenerative Diseases
• Cardiopulmonary and Vascular Medicine
• Translational Medicine and Drug Discovery

lung and breast cancer, myocarditis, oncolytic virus, protein/organelle quality control, RNA viruses, viral pathogenesis, virotherapy,  amyotrophic lateral sclerosis

Yes

No

No

• Cancer Research and Oncology
• Computational Biology and Bioinformatics
• Translational Medicine and Drug Discovery
• Molecular Genetics and Precision Medicine

drug discovery, drug resistance, early detection, Genomics, lung cancer, mouse models, signaling, therapeutics

Yes

Yes

No

• Neuroscience and Neurodegenerative Diseases
• Aging, Chronic Diseases, and Women’s Health

aging, axons, brain, histology, image analysis, image processing, imaging, microscopy, MRI, multiple sclerosis, myelin, neurodegeneration, neuroinflammation, neurology, pathology, physics, radiology, spinal cord, spinal cord injury