Pathology Province-Wide Rounds

Pathology Province-Wide Rounds
 
 
    
    

 
       
    

    
    
	
	 	
		 
            
           Dr. Honglin Luo, MD, MSc
            "Mastering Immune Chaos: Strategic Interventions for Viral Myocarditis via Innate Pathway Modulation"
                     
    Viral myocarditis remains the leading cause of heart failure and sudden death in children and young adults worldwide.   
    
        Despite great efforts, there is currently no clinically-proven treatment available. Dr. Luo will discuss her recent studies that explore the role of innate immunity in viral myocarditis, with the goal of developing innovative treatments for this disease. 
         (…) 
    

 
    
           
        
        
            15-Sept-23
			 
                
            
        
 
  

	
     
 	
		 
            
            Dr. Zu-hua Gao | Professor and Head, UBC Department of Pathology & Laboratory Medicine; Program Medical Director, Provincial Pathology & Laboratory Medicine, BC Cancer 
            "Strategic Plan: Transform the Future of Pathology and Laboratory Medicine"
            
 
    
           
        
        
            8-Sept-23
			 
                
            
        
 
  




 
		 
            
            Helene Cote, PhD, Professor and Program Director / Graduate Advisor, Graduate Studies Vice-Chair, Scientific Education,Department of Pathology and Laboratory Medicine, UBC 
            "PALM Graduate Program Curriculum Consultation"
            
           
    The field of Pathology and Laboratory Medicine is fast evolving with the advent of new technologies, as well as emerging research and clinical tools  
    
        The field of Pathology and Laboratory Medicine is fast evolving with the advent of new technologies, as well as emerging research and clinical tools. The objective of this consultation is to briefly review the courses currently offered as part of the PALM graduate curriculum, then discuss how our curriculum can best equip our graduate students for both their research projects and future career. We welcome input from current and past PALM trainees and their supervisors, Post-Doctoral Fellows, PALM Clinical faculty, residents, as well as other stakeholders.
         (…) 
    

    
           
        
        
            30-Jun-23
			 
                
            
        
 
  
  
  
  
	
    
        
        Deepu Alex, MD, PhD | Clinical Assistant Professor, UBC | Consultant Pathologist, BCCA 
        "Optimal histological assessment of tumor tissue for molecular testing and biomarker evaluation"
        

    Understand the current landscape of biomarkers required for the evaluation of different tumors;
    
        Learn the differing tumor tissue requirements based on the type of biomarker test being performed; Discuss strategies for best use of tumor tissue to allow for simultaneous evaluation of multiple biomarkers
         (…) 
    


 
 
    
        23-Jun-23
        
            
        
    




    
        
       Karsan, Aly, BA, MD (Queen's)| BC Cancer Research Centre | Professor, UBC, Distinguished Scientist
        "The Role of Noncoding Genes in the Pathogenesis and Vulnerabilities of Myeloid Cancers"
        

    Discuss how gene expression can improve risk stratification in myeloid cancers;
    
        Explain alternate mechanisms of therapy resistance in myeloid cancers; Discuss how genomics research will potentially shape the development of diagnostic and prognostic cancer assays.
         (…) 
    


 
 
    
        16-Jun-23
        
            
        
    



	
    
        
        Audi Setiadi, PhD| Hematopathologist at BC Children's Hospital | Clinical Assistant Professor at the University of British Columbia 
        "Capturing the Immune System: Implementation of the Flow Cytometry Panels for Immunodeficiency at BC Children's Hospital"
        

    Describe the role of Flow Cytometry in the laboratory approach for Primary Immunodeficiency (Inborn Errors of Immunity);
    
        Discuss the role of Flow Cytometry as Confirmatory test for SCID Newborn Screening;  Discuss the implementation of extended T, B and NK cell Flow Cytometry panels at BCCH and their clinical utility with real case examples.
         (…) 
    


 
 
    
      26-May-23
        
            
        
    



	
    
        
       Philipp Lange, PhD| Canada Research Chair in Translational Proteogenomics of Pediatric Malignancies | Assistant Professor of Pathology at the University of British Columbia| Scientist in the Michael Cuccione Childhood Cancer Research Program at the BC Children's Hospital and the BC Cancer Research Institute 
        "Canada's path towards proteome guided therapies and advanced molecular pathology in precision oncology"
        

    Understand what proteome profiling can contribute to precision oncology;
    
        Appreciate the benefit and potential feasibility of preemptive target identification; Learn how the Canadian Pediatric Cancer Consortium strives to advance pediatric cancer care and research.
         (…) 
    


 
 
    
     19-May-23
        
            
        
    



    
        
      Dr. Qihui Jim Zhai , MD, FCAP | Director of Research | Director FISH Laboratory | Professor and Consultant Pathologist | Mayo Clinic Florida | Governor, Chair Investment Committee | Vice Chair Council on Membership and Career Developmen
        "Applications of Novel Molecular Tests in Head and Neck Pathology: A Case-Based Approach"
        

    Develop an understanding of the morphologic spectrum of salivary gland tumors and the potential diagnostic pitfalls;
    
        Learn about the latest biomarkers used in the diagnosis and therapy of salivary gland tumors; Gain an understanding of the morphologic spectrum of HPV-mediated oropharyngeal squamous cell carcinoma and the applications of liquid biopsy in its diagnosis and management of patients.
         (…) 
    


 
 
    
     May 12 2003
        
            
        
    




    
        
      Dr. Andre Mattman, Clinical Professor, UBC , Medical Biochemist, St. Paul's Hospital, Medical Lead, Medical Biochemistry
        "Practicing Pathology in a CODE RED for Humanity"
        


 
 
    
     5-May-23
        
            
        
    





    
        
      Dr. Michael Nimmo, Clinical Professor, UBC, Program Director, UBC Residency Training Program in General Pathology, Pathologist, Vancouver General Hospital
        "'High' Volume Autoimmune testing in BC - An Overview Part 1"
        


 
 
    
    28-Apr-23
        
            
        
    




    
        
     Dr. Michelle Wong and Dr. Carolyn Shiau
        "Better together: the people, programs, and services of the lab in Fraser Health"
        

    To provide an overview of Fraser Health;
    
        To discuss initiatives within Fraser Health.
         (…) 
    


 
 
    
14-Apr-23
        
            
        
    



    
        
    Dr. Susan Porter - Dean and Vice-Provost, Graduate and Postdoctoral Studies at UBC
        "Changing Paradigms of Graduate Education in the 21st Century"
        

    Appreciate the workforce, societal, and environmental issues that are influencing the approaches and values of graduate education;
    
        Reflect on the assumptions inherent to current models of research graduate education; Consider ways in which biomedical graduate education and research could help meet the evolving needs of the 21st century.
         (…) 
    


 
 
    
31-Mar-23
        
            
        
    



    
        
   Dr. Cornelia (Corree) Laule |Associate Professor in the Departments of Pathology & Laboratory Medicine and Radiology | Associate Member of Physics & Astronomy | Vice Chair of Research in Radiology and Associate Director of the ICORD
        "Characterizing human brain and spinal cord microstructure with quantitative MRI and histology"
        

    To become familiar with different quantitative MRI methods used to study brain and spinal cord;
    
        To learn about post-mortem MRI validation studies in spinal cord injury; To review in vivo myelin MRI changes in different neurological conditions.
         (…) 
    


 
 
    
24-Mar-23
        
            
        
    




    
        
  Dr. Gang Wang, MD, PhD | Consultant Pathologist, BC Cancer | Director, The David Hardwick Pathology Learning Centre | Clinical Associate Professor, UBC
        "The David Hardwick Pathology Learning Centre (DHPLC): What is it, where did it come from and where is it going?"
        

    What is the history of DHPLC?;
    
        What is DHPLC doing? What is its future perspective?
         (…) 
    


 
 
    
17-Mar-23
        
            
        
    




    
         Presented by: Dr. David Goldfarb, Medical Microbiologist, BC Children's Hospital, Dr. Lien Hoang, Anatomic Pathologist, Vancouver General Hospital, Dr. Veronica Hirsch-Reinshagen, Neuropathologist, Vancouver General Hospital, Dr. Shazia Masud, Medical Microbiologist, Fraser Health, Dr. Danielle Meunier, Hematopathologist, Island Health, Dr. Tyler Smith, Hematopathologist, Vancouver General Hospital (moderator)
        "Panel Discussion on Career Planning and Job Applications"
        

    Develop their own approach and plan for career development that incorporates strategies discussed in the session;
    
        Identify important considerations when applying for positions or interviewing candidates.
         (…) 
    


 
 
    
10-Mar-23
        
            
        
    




    
        
 Citlali Marquez, PhD - Research Project Leader at BCCDC
        "Using the power of serological multiplex assays to track COVID-19"
        

    Introduce MSD’s multiplex assay and its applications on serological studies during COVID-19;
    
        Describe how antenatal residual samples can be used to track SARS-CoV-2 infection and vaccination rates in the general population; . Describe applications of multiplex testing beyond COVID-19
         (…) 
    


 
 
    
24-Feb-23
        
            
        
    



    
        
Agatha Jassem, PhD, FCCM, Program Head, Virology Lab, BCCDC PHL; President, BC Association of Clinical Scientists; Graham Sinclair, PhD, FCCMG, Biochemical Geneticist, BC Newborn Screening Lab, BCCH; Tanya Nelson, PhD, FCCMG, Division Head, Genome Diagnostics, BCCH; Tracy Tucker, PhD, FCCMG  Clinical Cytogenetics and Molecular Geneticists  Cancer Genetics and Genomics Laboratory, BC Cancer
        "Clinical Scientists in Action"
        

    Define the role of Clinical Scientists in healthcare service delivery in BC;
    
        Describe recent testing advancements within newborn screening in BC; Describe recent advances in clinical genome diagnostics in BC and related policy development; Describe new genetic testing initiatives in cancer care in BC.
         (…) 
    


 
 
    
17-Feb-23
        
            
        
    





    
        
Presented by: Dr. Tyler Smith, Hematopathology (Chair); Dr. David Huntsman, Molecular and Genomic Pathology; Dr. Daniel Holmes, Medical Biochemistry; Dr. Marthe Charles, Medical Microbiology; Dr. Andrew Shih, Transfusion Medicine
        "Panel Discussion - Laboratory Medicine and Private Industry"
        

    Describe ways in which relationships can be beneficial with private industry;
    
        Highlight some of the potential conflicts of interest to navigate when dealing with private industry; Formulate their own ethical approach to their private industry relationships.
         (…) 
    


 
 
    
10-Feb-23
        
            
        
    





    
        
Dr. Veronica Hirsch-Reinshagen - Neuropathologist at ICORD and Assistant Professor, and Dr. Mike Nimmo - Clinical Professor, Vice Chair Clinical Education and Residency Program Director
        "Scientific method and a book of spells: Bringing neurological and systemic autoantibody testing to BC"
        

    Understand the basic principles of autoantibody testing methodology; 
    
        Review the type and clinical relevance of neurological autoantibody testing to be implemented in BC.
         (…) 
    


 
 
    
3-Feb-23
        
            
        
    





    
        
Dr. Ying Wang, PhD,  Assistant Professor, Centre for Heart Lung Innovation
        "Characterizing atherosclerosis at the molecular level to improve treatment outcome of anti-inflammatory therapies"
        

    1.	Tackle the problems seen in the CANTOS trial: using multiplex imaging to define the 'bad' cytokines in human coronary lesions. 
    
        2.	Discuss who will benefit from colchicine:  defining the therapeutic targets of colchicine in clinically relevant models and human coronary lesions. 
         (…) 
    


 
 
    
27-Jan-23
        
            
        
    


  
    
        
Dr. Lucy Perrone, Donald B. Rix Professor in Laboratory Quality at UBC
        "The Canadian Microbiology Proficiency Testing Program (CMPT): A Clinical Service and External Quality Assessment Partner for Laboratories Performing Microbiology Testing"
        

    What does CMPT do to support diagnostic testing quality including test accuracy?; 
    
         How does CMPT support public and environmental health?   
 How does CMPT implement its programs and provide continuing education to subscribing laboratories and community-based testing sites? How is CMPT peer-directed and how you might get involved. 
         (…) 
    


 
 
    
20-Jan-23
        
            
        
    


      

	 


    
       	
		 
            
         Dr. Ivan Chebib, Director of Immunohistochemistry Laboratory, Massachusetts General Hospital
Assistant Professor of Pathology, Harvard Medical School
            "International System for Reporting Soft Tissue Cytopathology"
  
           
        
        
            9-Dec-22
			 
                
            
        
 
  
   
   
       	
		 
            
        James Piret (MSL)
            "Noninvasive Technology Development for Monitoring and Validating Cell Therapy Manufacturing"

    
           
        
        
          2-Dec-22
			 
                
            
        
 
  
   
         	
		 
            
     Dr. Daniel Holmes, Clinical Professor, Dept of Pathology and Laboratory Medicine; Division Head, Clinical Chemistry, St.Paul's Hospital
            "SPH Pathology and Laboratory Medicine"

 
    
           
        
        
          25-Nov-22
			 
                
            
        
 
  
   
   
   	
		 
            
            Dr. Larry Barzelai, MD, CCFP (family physician), Assistant Professor UBC, Chair of the BC Branch of the Canadian Association of Physicians for the Environment
            "Climate Change is the Crucial Health Issue of Our Time"

 
    
           
        
        
           18-Nov-22
			 
                
            
        
 
  

  	
		 
            
         Dr. Wan Lam, Director of the Interdisciplinary Oncology Program at BC Cancer Research and Professor at UBC
            "Understanding Lung Cancer Molecular Biology in Smokers and Non-smokers"
                     
    To gain understanding on current research in lung cancer molecular biology;  
    
        To gain understanding of how lung cancer in smokers and never smokers may develop through different genetic mechanisms. 
         (…) 
    

 
    
           
        
        
        4-Nov-22
			 
                
            
        
 
  
	
		 
            
         Jane Cooke-Lauder
            "DEPARTMENT TOWN HALL: Creating our Strategic Plan"
     
           
        
        
       28-Oct-02
			 
                
            
        
 
  


		 
            
        Peter Lansdorp, Distinguished Scientist, Terry Fox Laboratory, BC Cancer; Professor, Medical Genetics, UBC
            "Telomerase and Cell renewal in the context of Evolution Biology"
                     
    Learning Objectives: recognize clinical features of telomere biology disorders; 
    
        appreciate telomere shortening as a powerful tumor suppressor mechanism that limits cell renewal in the hematopoietic, immune and cardiovascular system;   consider a novel model to explain why females have longer telomeres and live longer than males. 
         (…) 
    

 
    
           
        
        
      21-Oct-22
			 
                
            
        
 
  


		 
            
        Dr. Michael Chen - Co-Chair, BC COVID-19 Biobank Network and Head, Medical Biochemistry, Island Health
            "BC COVID-19 Biobank Network (BCCBN): Promoting Access and Enabling Research"
                     
    Learning Objectives: introduce BCCBN as a province-wide platform for biobanking; 
    
        describe BCCBN developments and subsequent benefits;   discuss specimen access and future directions.  
         (…) 
    

 
    
           
        
        
      07-Oct-22
			 
                
            
        
 
 
 
 
 
		 
            
        Craig Ivany, Chief Provincial Diagnostics Officer
            "Overview of the British Columbia laboratory service delivery model"
                     
    Learning Objectives:  identify and explore the nature of the laboratory service delivery sector in British Columbia;   
    
         identify and explore some of the contextual tensions that lab leaders may face;  implications/opportunities for the future of laboratory services in British Columbia. 
         (…) 
    

 
    
           
        
        
     23-Sep-22
			 
                 This video is password protected, contact  Mayumi Shimada   to get an access.
            
        
 
 


		 
            
        Drs. Agatha Jassem and Mark Hull from BCCDC
            "The emergence of monkeypox in BC: clinical findings and BC testing data"
                     
    Learning Objectives: review clinical presentation of monkeypox;
    
        management options for symptomatic infection.  
         (…) 
    

 
    
           
        
        
    16-Sep-22
			 
                
            
        
 
 
 
		 
            
    Dr. Michael S. Kobor, Professor of Medical Genetics
            "Epigenetics and the Human Life Course"
                     
    Learning Objectives: to learn about the importance and complexity of epigenetics across the human life course;
    
         to understand the various ways by which the epigenome can inform on human health and disease; to explore opportunities for collaborative research in human epigenetics and learn about the new Edwin S.H. Leong Healthy Aging Program at UBC. 
         (…) 
    

 
    
           
        
        
9-Sep-22
			 
                
            
        
 
 

 
		 
            
  Dr. Suzanne Vercauteren, Head & Medical Director at BC Children’s and Women’s Hospital
            "Equity, Diversity and Inclusion"
                     
    Learning Objectives: 	Understand what EDI is and what the benefits are of implementing EDI in the work environment 
    
         Gain insight in the EDI survey results from our Department; Discuss actions the department can undertake to further EDI 
         (…) 
    

 
    
           
        
        
24-Jun-22
			 
                
            
        
 
 
 
 
 
		 
            
Dr. Kevin Ko, Oral Pathology
            "Pearls and Pitfalls in Oral and Maxillofacial Pathology"
                     
    Learning Objectives: 	discuss the importance of  clinical-radiological correlation in diagnosing odontogenic and non-odontogenic jaw lesions;
    
         recognize the pitfalls in diagnosing oral mucosal lesions, with an emphasis on oral potentially malignant disorders. 
         (…) 
    

 
    
           
        
        
17-Jun-22
			 
                
            
        
 
 
 
  
		 
            
Anna Blakney, Assistant Professor in the Michael Smith Laboratories and School of Biomedical Engineering at UBC
            "Next Generation RNA Vaccines"
                     
    Learning Objectives:  current challenges in the field of RNA vaccines; 
    
         advantages of self-amplifying RNA compared to messenger RNA; strategies for improving safety and efficacy of future RNA vaccines.  
         (…) 
    

 
    
           
        
        
10-Jun-22
			 
                
            
        
 
 
 
 
  
		 
            
Titus Wong, Clinical Assistant Professor, Regional Medical Director of Infection Control and Dr. Jennifer Grant, Clinical Associate Professor, Medical Microbiologist and Infectious Diseases Physician, VGH
            "COVID-19: Practice update and Preparations for the Summer/Fall"
                     
    Learning Objectives:  review current provincial COVID-19 epidemiology; 
    
         review current provincial safety recommendations;  review current provincial COVID-19 therapy recommendations;    
discuss provincial preparations for the fall.  
         (…) 
    

 
    
           
        
        
20-May-22
			 
                
            
        
 
 
 
  
		 
            
Peter Zandstra, Director and Professor, School of Biomedical Engineering, UBC

            "How tissues are built"

 
    
           
        
        
13-May-22
			 
                
            
        
 
 
  
		 
            
Michelle Dittrick

            "Practical tips and tricks for launching a research study"
                     
    Learning Objectives:  review the challenges faced in starting a research study and alternative approaches to consider; 
    
        learn practical tips to facilitate study approvals;  identify local resources available to researchers.  
         (…) 
    

 
    
           
        
        
6-May-22
			 
                
            
        
 
 
 
		 
            
Mike Nimmo  - Vice chair Education

            "Education in the UBC Department of Pathology - the present state and future directions"
                     
    Learning Objectives:  describe current educational areas/activities within the Department;  
    
        list issues facing pathology education within the Department; describe the future directions of educational activities within the department.  
         (…) 
    

 
    
           
        
        
29-Apr-22
			 
                
            
        
 
 
 
		 
            
Naveena Singh, Clinical Professor, UBC and Anatomic Pathologist, Vancouver General Hospital

            "Update on vulvar squamous cell carcinoma and its precursors"
                     
    Learning Objectives:  to understand the current etiology-based classification of VSCC and its precursor lesions;   
    
        to understand the importance and learn the expression patterns of p16 and p53 immunohistochemistry;  to become familiar with the terminology and approach to diagnosis of HPV-independent, p53-wild type VSCC precursors.  
         (…) 
    

 
    
           
        
        
22-Apr-22
			 
                
            
        
 
 
 
 
		 
            
Jennifer Cooper, Graduate Student Djavad Mowafaghian Centre for Brain Health

            "COVID-19 and the brain: what neurological blood based biomarkers can tell us about neurological consequences of COVID-19 in critically ill patients"
                     
    Learning Objectives:  gain knowledge about what neurological biomarkers can tell us about the central nervous system;   
    
        understand the utility of blood based neurological biomarkers as clinical tools; examine these biomarkers in a population of critically ill patients with COVID-19.  
         (…) 
    

 
    
           
        
        
8-Apr-22
			 
                 Presented with Haifeng Zhang (see video below)
            
        
 
 
 
  
		 
            
 Haifeng  Zhang, Research Associate BC Cancer Research Centre

            "Identification and targeting of a tumor cell surface protein via immunotherapy strategies"
                     
    Learning Objectives:  how cancer cells evade cell death under oxidative stress; 
    
        how cancer cells augment cysteine metabolism as a cytoprotection mechanism;  
         (…) 
    

 
    
           
        
        
8-Apr-22
			
              
           
        
 
 
  
		 
            
Dr. Cheryl Wellington, Professor and Vice Chair of Research, Dept of Pathology and Laboratory Medicine, UBC, Djavad Mowafaghian Centre for Brain Health, ICORD

            "Vision and initial goals"
                     
    Learning Objectives:  introduce myself as Vice Chair of Research (VCR), Dept of Pathology & Lab Medicine;  
    
         describe my initial vision as VCR;  > outline short and medium term goals for VCR;     
 invite participation on the VCR committee.    
         (…) 
    

 
    
           
        
        
1-Apr-22
			 
                
            
        
 
 
  
		 
            
 Gao, Zu-hua, Professor and Department Head Department of Pathology and Laboratory Medicine, UBC

            "Liver biopsy interpretation"
                     
    Learning Objectives:  systematic approach to liver biopsy; 
    
          interpretation based on patterns of abnormality; overview of morphological characteristics of common liver diseases.  
         (…) 
    

 
    
           
        
        
25-Mar-22
			 
                
            
        
 
 
 
 
   
		 
            
Jay Kizhakkedathu Professor, Pathology and Laboratory Medicine, Michael Smith Foundation for Health Research Scholar

            "Immunomodulating cell-surface engineering towards improved transfusion and transplantation"
                     
    Learning Objectives: understand the development of blood group antigen conversion towards universal red blood cells, and their immunological compatibility; 
    
          understand the development of immuno-cloaking approaches using novel immune-suppressing polymers to prevent transplant rejection.  
         (…) 
    

 
    
           
        
        
18-Mar-22
			
        
 
 
 
  
		 
            
 Gao, Zu-hua, Professor and Department Head Department of Pathology and Laboratory Medicine, UBC

            "My First 100 Days"
                     
    Learning Objectives:  identify the strength and issues of the department; 
    
           summary suggestions from faculty members;  iscuss plans forward.  
         (…) 
    

 
    
           
        
        
25-Mar-22
			 
                view PDF presentation