publications 2021

NameDescriptionPublication TypeDate
Agatha JassemHogan CA, Jassem AN, Sbihi H, Joffres Y, Tyson JR, Noftall K, Taylor M, Lee T, Fjell C, Wilmer A, Galbraith J, Romney MG, Henry B, Krajden M, Galanis E, Prystajecky N, Hoang LMN. Rapid Increase in SARS-CoV-2 P.1 Lineage Leading to Codominance with B.1.1.7 Lineage, British Columbia, Canada, January-April 2021. Emerg Infect Dis. 2021;27(11):2802-2809.1. journals2021
Agatha JassemMajdoubi A, Michalski C, O'Connell SE, Dada S, Narpala S, Gelinas J, Mehta D, Cheung C, Winkler DF, Basappa M, Liu AC, Görges M, Barakauskas VE, Irvine M, Mehalko J, Esposito D, Sekirov I, Jassem AN, Goldfarb DM, Pelech S, Douek DC, McDermott AB, Lavoie PM. A majority of uninfected adults show preexisting antibody reactivity against SARS-CoV-2. JCI Insight. 2021;6(8):e146316.1. journals2021
Agatha JassemNikiforuk AM, Kuchinski KS, Twa DDW, Lukac CD, Sbihi H, Basham CA, Steidl C, Prystajecky NA, Jassem AN, Krajden M, Patrick DM, Sekirov I. The contrasting role of nasopharyngeal angiotensin converting enzyme 2 (ACE2) transcription in SARS-CoV-2 infection: A cross-sectional study of people tested for COVID-19 in British Columbia, Canada. EBioMedicine. 2021;66:103316.1. journals2021
Agatha JassemNikiforuk AM, Karim ME, Patrick DM, Jassem AN. Influence of chronic hepatitis C infection on the monocyte-to-platelet ratio: data analysis from the National Health and Nutrition Examination Survey (2009-2016). BMC Public Health. 2021;21(1):1388.1. journals2021
Agatha JassemSherwood KR, Nicholl D, Fenninger F, Wu V, Wong P, Benedicto V, Cina DP, Wang M, Pobran TD, De Marco ML, Márquez AC, Jassem AN, Sekirov I, Morshed MG, Bardi M, Sekhon M, Keown P, Kadatz M, Lan JH. Comprehensive Immune Profiling of a Kidney Transplant Recipient With Peri-Operative SARS-CoV-2 Infection: A Case Report. Front Immunol. 2021;12:753558. 1. journals2021
Agatha JassemCaza M, Hogan CA, Jassem A, Prystajecky N, Hadzic A, Wilmer A. Evaluation of the clinical and analytical performance of the Seegene allplex„¢ SARS-CoV-2 variants I assay for the detection ofvariants of concern (VOC) and variants of interests (VOI). J Clin Virol. 2021;144:104996. 1. journals2021
Agatha JassemGrunau B, Asamoah-Boaheng M, Lavoie PM, Ehsanul Karim M, Kirkham T, Demers PA, Barakauskas V, Citlali Marquez A, Jassem AN, O'Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM. A Higher Antibody Response is Generated with a 6 - 7 Week (vs Standard) SARS-CoV-2 Vaccine Dosing Interval. Clin Infect Dis. 2021. 1. journals2021
Agatha JassemMcClymont E, Elwood C, Sekirov I, Morshed M, Levett P, Liu A, Jassem A, Sbihi H, Ogilvie G, Krajden M, Money D. Population SARS-CoV-2 Seroprevalence Using Antenatal Serum Samples in British Columbia, Canada. J Obstet Gynaecol Can. 2021;43(11):1242-1243.1. journals2021
Ali BashashatiJulia R. Naso, Adrian B. Levine, Hossein Farahani, Lucian R. Chirieac, Sanja Dacic, Joanne L. Wright, Chi Lai, Hui-Min Yang, Steven J. M. Jones, Ali Bashashati, Stephen Yip & Andrew Churg, "Deep learning based classification distinguishes sarcomatoid malignant mesotheliomas from benign spindle cell mesothelial proliferations," Modern Pathology, Jul 2021 (Role: CA, IF = 8).1. journals2021
Ali BashashatiJessica A Pilsworth, Dawn R Cochrane, Samantha J Neilson, Bahar H Moussavi, Daniel Lai, Aslı D Munzur, Janine Senz, Yi Kan Wang, Sina Zareian, Ali Bashashati, Adele Wong, Jacqueline Keul, Annette Staebler, Hannah S van Meurs, Hugo M Horlings, Stefan Kommoss, Friedrich Kommoss, Esther Oliva, Anniina EM Färkkilä, Blake Gilks, David G Huntsman, "Adult€type granulosa cell tumor of the ovary: a FOXL2€centric disease," The Journal of Pathology: Clinical Research. May 2021 (Role: CA, IF = 5.6).1. journals2021
Ali BashashatiJeffrey Boschman, Hossein Farahani, Amirali Darbandsari, Pouya Ahmadvand, Ashley Van Spankeren, David Farnell, Adrian Levine, Julia R. Naso, Andrew Churg, Steven Jones, Stephen Yip, Martin Koebel, David Huntsman, Blake Gilks, Ali Bashashati, "The Utility of Color Normalization for AI-Based Diagnosis of Hematoxylin and Eosin-Stained Pathology Images,"  Journal of Pathology, Sep 2021 (Role: SA, IF = 8).1. journals2021
Ali BashashatiYanan Shao, Davood Karimi, Jane Wang, Ladan Fazli, S. Larry Goldenberg, Martin E. Gleave, Peter C. Black, Ali Bashashati*, and Septimiu Salcudean*, "Improved Prostate Cancer Risk Stratification by Digital Histopathology and Deep Learning," Modern pathology, Oct 2021 (submitted). (Role: SA, IF = 8, *co-corresponding authors).1. journals2021
Allison Matthewsvan der Crabben SN, van Amstel T, Matthews AM, Drögemoller BM, Ghani A, Ross CJ, Wasserman WW, M. van der Kamp JM, Steinraths M, van Karnebeek CDM. SATB2-associated syndrome with a novel mutation and literature overview illustrate alkaline phosphatase as useful biomarker in the diagnostic work-up of undiagnosed syndromal intellectual disability patients. Submitted to Cold Spring Harbour MCS: special issue Rare Diseases [CA]1. journals2021
Allison MatthewsInkster AM, Yuan V, Konwar C, Matthews AM, Brown CJ, Robinson WP. A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta. Biol Sex Differ. 2021 May 27;12(1):38. doi: 10.1186/s13293-021-00381-4. PMID: 34044884; PMCID: PMC8162041. [CA]1. journals2021
Allison Matthewsvan Karnebeek CD, Blydt-Hansen I, Matthews AM, Avramovic V, Price M, Drogemoller B, Shyr C, Lee J, Mwenifumbo J, Ghani A, Stockler S, Friedman JM, Lehman A; CAUSES Genomic Study, Ross CJ, Wasserman WW, Tarailo-Graovac M, Horvath GA. Secondary biogenic amine deficiencies: genetic etiology, therapeutic interventions, and clinical effects. Neurogenetics. 2021 Oct;22(4):251-262. doi: 10.1007/s10048-021-00652-7. Epub 2021 Jul 2. PMID: 34213677. [CA]1. journals2021
Allison MatthewsEstey MP, Tahooni T, Nelson TN, Parker ML, Agbor TA, Yang HM, Jen R, Barakauskas VE, Lam GY, Matthews A, Mattman A. Is the diagnostic rate for the common subtypes of A1AT deficiency consistent across two Canadian Provinces? Clin Biochem. 2021 Sep;95:84-88. doi: 10.1016/j.clinbiochem.2021.05.002. Epub 2021 May 6. PMID: 33964271. [CA]1. journals2021
Aly KarsanShickh S, Oldfield L, Clausen M, Mighton C, Sebastian A, Calvo A, Baxter NN, Dawson L, Penney LS, Foulkes W, Basik M, Sun S, Schrader KA, Regier DA, Karsan A, Pollett A, Pugh TJ, Kim RH, Bombard Y on behalf of the CHARM Consortium. Game Changer: Health professionals€™ views on the clinical utility of circulating tumor DNA testing in hereditary cancer syndrome management. The Oncologist  (accepted)1. journals2021
Aly KarsanWong SK, Alex D, Bosdet I, Hughesman C, Karsan A, Yip S, Ho C. MET exon 14 skipping mutation positive non - small cell lung cancer: Response to systemic therapy. Lung Cancer. 2021 Apr;154:142 - 145. PMID: 336677191. journals2021
Aly KarsanStarks ER, Swanson L, Docking TR, Bosdet I, Munro S, Moore RA, Karsan A. Assessing Limit of Detection in Clinical Sequencing. J Mol Diagn. 2021 Apr;23(4):455 - 466. PMID: 334860751. journals2021
Aly KarsanMighton C, Smith AC, Mayers J, Tomaszewski R, Taylor S, Hume S, Agatep R, Spriggs E, Feilotter HE, Semenuk L, Wong H, Lazo de la Vega L, Marshall CR, Axford MM, Silver T, Charames GS, Di Gioacchino V, Watkins N, Foulkes WD, Clavier M, Hamel N, Chong G, Lamont RE, Parboosingh J, Karsan A, Bosdet I, Young SS, Tucker T, Akbari MR, Speevak MD, Vaags AK, Lebo MS, Lerner - Ellis J; Canadian Open Genetics Repository Working Group. Data sharing to improve concordance in variant interpretation across laboratories: results from the Canadian Open Genetics Repository. J Med Genet. 2021 Apr 19:jmedgenet - 2021 - 107738. PMID: 33875564 [online ahead of print]1. journals2021
Aly KarsanDocking TR, Parker JDK, Jädersten M, Duns G, Chang L, Jiang J, Pilsworth JA, Swanson LA, Chan SK, Chiu R, Nip KM, Mar S, Mo A, Wang X, Martinez - Høyer S, Stubbins RJ, Mungall KL, Mungall AJ, Moore RA, Jones SJM, Birol İ, Marra MA, Hogge D, Karsan A. A clinical transcriptome approach to patient stratification and therapy selection in acute myeloid leukemia. Nat Commun. 2021 Apr 30;12(1):2474. PMID: 339316481. journals2021
Aly KarsanStubbins RJ, Karsan A. Differentiation therapy for myeloid malignancies: beyond cytotoxicity. Blood Cancer J. 2021 Dec 4;11(12):193. PMID: 348648231. journals2021
Aly KarsanSamimi H, Mehta I, Docking TR, Zainulabadeen A, Karsan A*, Zare H*. DNA methylation analysis improves the prognostication of acute myeloid leukemia. eJHaem. 2021 May; 2(2):211-218. PMID: 34308417 (*co - senior authors)1. journals2021
Aly KarsanWeymann D, Pollard S, Chan BN, Titmuss E, Bohm A, Laskin J, Jones SJM, Pleasance E, Nelson J, Fok A, Lim H, Karsan A, Renouf DJ, Schrader KA, Sun SP, Yip S, Schaeffer DF, Marra M, Regier Da. Clinical and cost outcomes following genomics-informed treatment for advanced cancers. Cancer Med. 2021 Aug;10(15):5131-5140; PMID: 341520871. journals2021
Aly KarsanLau T, May C, Dashti Z, Swanson L, Starks E, Parker JDK, Moore R, Tucker T, Bosdet I, Young S, Santos J, Compton K, Heidary N, Hoang L, Schrader K, Sun S, Kwon J, Tinker A, Karsan A. Use of Treatment-Focused Tumor Sequencing to Screen for Germline Cancer Predisposition. J Mol Diagn. 2021 Sep; 23(9): 1145-1158. PMID: 341979221. journals2021
Aly KarsanFibke C, Giroux S, Caron A, Starks E, Parker JDK, Swanson L, Jouan L, Langlois S, Rouleau G, Rousseau F, Karsan A. Effect of preexamination conditions in a centralized-testing model of non-invasive prenatal screening. Clin Chem Lab Med. 2021 Nov 11 PMID: 34761647 (online ahead of print/ Print 2022 Jan 27)1. journals2021
Aly KarsanGopal A, Ibrahim R, Fuller M, Umlandt P, Parker J, Tran J, Chang L, Wegrzyn - Woltosz J, Lam J, Li J, Lu M, Karsan A. TIRAP drives myelosuppression through an IfnGamma- Hmgb1 axis that disrupts the endothelial niche in mice. J Exp Med. DOI:10.1084/jem.20200731 (accepted)1. journals2021
Aly KarsanXu R, Karsan A, Xu Z, Berry BR. A rare de novo pure erythroid leukemia with JAK2 R683S mutation. Ann Hematol. 2021 Sep 4. PMID: 34480614 (online ahead of print)1. journals2021
Aly KarsanCheung CC, Smith AC, Albadine R, Bigras G, Bojarski A, Couture C, Cutz JC, Huang WY, Ionescu D, Itani D, Izevbaye I, Karsan A, Kelly MM, Knoll J, Kwan K, Nasr MR, Qing G, Rashid-Kolvear F, Sekhon HS, Spatz A, Stockley T, Tran-Thanh D, Tucker T, Waghray R, Wang H, Xu Z, Yatabe Y, Torlakovic EE, Tsao MS. Canadian ROS proto-oncogene 1 study (CROS) for multi-institutional implementation of ROS1 testing in non-small cell lung cancer. Lung Cancer. 2021 Oct; 160:127-135. PMID: 345090951. journals2021
Amanda WilmerBoyd DA, Mataseje LF, Dingle T, Hoang L, Lefebvre B, McGeer A, Melano RG, Stuart I, Walkty A, WILMER A, Mulvey MR. 2021.Emergence of Morganellaceae harboring blaIMP-27 metalloenzyme in Canada. mSphere 6:e00048-21. https://doi.org/10.1128/mSphere.00048-21.1. journals2021
Amanda WilmerCatherine A. Hogan, Agatha N. Jassem, Hind Sbihi, Yayuk Joffres, John R. Tyson, Kyle Noftall, Marsha Taylor, Tracy Lee, Chris Fjell, AMANDA WILMER, John Galbraith, Marc G. Romney, Bonnie Henry, Mel Krajden, Eleni Galanis, Natalie Prystajecky, and Linda M.N. Hoang. Rapid Increase in SARS-CoV-2 P.1 Lineage Leading to Codominance with B.1.1.7 Lineage, British Columbia, Canada, January€“April 2021.  Emerging Infectious Diseases 2021 27(11).1. journals2021
Amanda WilmerCaza M, Hogan C, Jassem A, Prystajecky N, Hadzic A, WILMER A. Evaluation of the clinical and analytical performance of the Seegene allplex„¢ SARS-CoV-2 variants I assay for the detection of variants of concern (VOC) and variants of interests (VOI). Journal of Clinical Virology 2021 144:104996. doi: 10.1016/j.jcv.2021.1049961. journals2021
Amir KarinKarin A, Kulasingam V, Chartier LB, Ejumudo A, Wolff T, Brinc D. Recurring Critical Results and Their Impact on the Volume of Critical Calls at a Tertiary Care Center. J Appl Lab Med. 2021 Feb 13:jfab001. doi: 10.1093/jalm/jfab001. Epub ahead of print. PMID: 33582795.1. journals2021
Amir KarinKarin A, Brinc D, Leung F, Jung BP. Inaccuracy of Sodium Measurement in Patients with Severe Hypernatremia. J Appl Lab Med. 2021 Mar 1;6(2):463-467. doi: 10.1093/jalm/jfaa102. PMID: 32995891.1. journals2021
Andre MattmanTan A, Sinclair G, Mattman A, Vallance HD, Lamers Y. Maternal vitamin B12 status in early pregnancy and its association with birth outcomes in Canadian mother€“newborn Dyads. British Journal of Nutrition. 2021 Feb 19:1-9.1. journals2021
Andre MattmanZhao EJ, Cheng CV, Mattman A, Chen LY. Polyclonal hypergammaglobulinaemia: assessment, clinical interpretation, and management. The Lancet Haematology. 2021 May 1;8(5):e365-75.1. journals2021
Andre Mattmanvan der Gugten G, Mattman A, Ritchie G, Chen LY, Chin A, Holmes DT, Mills JR, Rao LV. Method Limitations in LC-MS/MS and Immunonephelometric Measurement of IgG Subclasses. Clinical Chemistry. 2021 Feb;67(2):440-1.1. journals2021
Andre MattmanAlotaibi NM, Leitao Filho FS, Mattman A, Hollander Z, Chen V, Ng R, Leung JM, Sin DD. Immunoglobulin G Levels and Mortality in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. 2021 May 4(ja).1. journals2021
Andre MattmanEstey MP, Tahooni T, Nelson TN, Parker ML, Agbor TA, Yang HM, Jen R, Barakauskas VE, Lam GY, Matthews A, Mattman A. Is the diagnostic rate for the common subtypes of A1AT deficiency consistent across two Canadian Provinces?. Clinical Biochemistry. 2021 May 6.1. journals2021
Andre MattmanZhan SH, Nicolson H, Takahashi A, Mattman A. Lactate and glucose as additional considerations to the plasma sodium level-corrected erythrocyte mean corpuscular volume report when using the Sysmex XE-2100. Clinica Chimica Acta. 2021 Mar 1;514:96-9.1. journals2021
Andre MattmanAtkins P, Mattman A, Thompson D. Falsely elevated serum estradiol due to heterophile antibody interference: a case report. Archives of Endocrinology and Metabolism. 2021 Feb 24;65:237-41.1. journals2021
Andre MattmanFung AW, Mattman A, Wang L, Burton T, Beach LA, Füzéry AK. Intrapartum Fetal Scalp Lactate Testing: Considerations for Implementation and Clinical Decision Making. Journal of obstetrics and gynaecology Canada: JOGC= Journal d'obstetrique et gynecologie du Canada: JOGC. 2021 Nov;43(11):1244-6.1. journals2021
Andrew ChurgYang H, Cheung S, Churg A. UHRF1 Immunohistochemical Staining Separates Benign Reactive Spindle Cell Mesothelial Proliferations From Sarcomatoid Mesotheliomas. Am J Surg Pathol. 2021 Nov 15. doi: 10.1097/PAS.0000000000001840. Epub ahead of print. PMID: 34772842.1. journals2021
Andrew ChurgYang SR, Beasley MB, Churg A, Colby TV, Fernández Pérez ER, Lynch D, Müller NL, Travis WD. Diagnosis of Hypersensitivity Pneumonitis: Review and Summary of American College of Chest Physicians Statement. Am J Surg Pathol. 2021 Nov 11. doi: 10.1097/PAS.0000000000001827. Epub ahead of print. PMID: 34753865.1. journals2021
Andrew ChurgChurg A, Ryerson CJ, Wright JL. Fibroblast Foci and Patchy Fibrosis Do Not Separate Usual Interstitial Pneumonia From Fibrotic Hypersensitivity Pneumonitis in Transbronchial Cryobiopsies. Arch Pathol Lab Med. 2021 Nov 1;145(11):1325-1326. doi: 10.5858/arpa.2021-0234-LE. PMID: 34673908.1. journals2021
Andrew ChurgBoschman J, Farahani H, Darbandsari A, Ahmadvand P, Van Spankeren A, Farnell D, Levine AB, Naso JR, Churg A, Jones SJ, Yip S, Köbel M, Huntsman DG, Gilks CB, Bashashati A. The utility of color normalization for AI-based diagnosis of hematoxylin and eosin-stained pathology images. J Pathol. 2021 Sep 20. doi: 10.1002/path.5797. Epub ahead of print. PMID: 34543435.1. journals2021
Andrew ChurgChurg A. Hypersensitivity pneumonitis: new concepts and classifications. Mod Pathol. 2021 Sep 16. doi: 10.1038/s41379-021-00866-y. Epub ahead of print. PMID: 34531525.1. journals2021
Andrew ChurgRoy S, Galateau-Sallé F, Le Stang N, Churg A, Lyons MA, Attanoos R, Dacic S. Molecular characterization of pleomorphic mesothelioma: a multi-institutional study. Mod Pathol. 2021 Sep 16. doi: 10.1038/s41379-021-00900-z. Epub ahead of print. PMID: 34531524.1. journals2021
Andrew ChurgNaso JR, Tessier-Cloutier B, Senz J, Huntsman DG, Churg A. Significance of p53 immunostaining in mesothelial proliferations and correlation with TP53 mutation status. Mod Pathol. 2021 Sep 8. doi: 10.1038/s41379-021-00920-9. Epub ahead of print. PMID: 34497363.1. journals2021
Andrew ChurgChurg A, Le Stang N, Dacic S, Pissaloux D, Begueret H, Dartigues P, Giusiano-Courcambeck S, Sequeiros R, Pairon JC, Tirode F, Galateau-Sallé F. Solid papillary mesothelial tumor. Mod Pathol. 2021 Sep 3. doi: 10.1038/s41379-021-00899-3. Epub ahead of print. PMID: 34480081.1. journals2021
Andrew ChurgChurg A, Galateau-Salle F, Tan L, Qing G. Cytological diagnosis of mesothelioma in situ versus invasive mesothelioma. Pathology. 2021 Jul 29:S0031-3025(21)00403-7. doi: 10.1016/j.pathol.2021.04.011. Epub ahead of print. PMID: 34334179.1. journals2021
Andrew ChurgNaso JR, Levine AB, Farahani H, Chirieac LR, Dacic S, Wright JL, Lai C, Yang HM, Jones SJM, Bashashati A, Yip S, Churg A. Deep-learning based classification distinguishes sarcomatoid malignant mesotheliomas from benign spindle cell mesothelial proliferations. Mod Pathol. 2021 Nov;34(11):2028-2035. doi: 10.1038/s41379-021-00850-6. Epub 2021 Jun 10. PMID: 34112957.1. journals2021
Andrew ChurgNaso JR, Cheung S, Ionescu DN, Churg A. Utility of SOX6 and DAB2 for the Diagnosis of Malignant Mesothelioma. Am J Surg Pathol. 2021 Sep 1;45(9):1245-1251. doi: 10.1097/PAS.0000000000001712. PMID: 33782226.1. journals2021
Andrew ChurgKlebe S, Nakatani Y, Dobra K, Butnor KJ, Roden AC, Nicholson AG, Marchevsky AM, Husain AN, Segal A, Walts AE, Weynand B, Michael CW, Dacic S, Godbolt D, Attanoos R, Santoni-Rugiu E, Galateau-Salle F, Hiroshima K, Moreira AL, Burn J, Nabeshima K, Gibbs AR, Churg A, Litzky LA, Brcic L, Tsao MS, Mino-Kenudson M, Rørvig SB, Tazelaar HD, Krausz T, Zhang YZ, Chirieac LR, Beasley MB, Hjerpe A. The concept of mesothelioma in situ, with consideration of its potential impact on cytology diagnosis. Pathology. 2021 Jun;53(4):446-453. doi: 10.1016/j.pathol.2020.12.005. Epub 2021 Mar 26. PMID: 33775406.1. journals2021
Andrew ChurgSalisbury T, Churg A. CD146 immunohistochemical staining for the separation of benign from malignant mesothelial proliferations. Virchows Arch. 2021 Nov;479(5):1047-1050. doi: 10.1007/s00428-021-03077-7. Epub 2021 Mar 15. PMID: 33721119.1. journals2021
Andrew ChurgArif AA, Kim PTW, Melck A, Churg A, Schwartz Z, Stuart HC. Pancreatic Gastrinoma, Gastrointestinal Stromal Tumor (GIST), Pheochromocytoma, and Hürthle Cell Neoplasm in a Patient with Neurofibromatosis Type 1: A Case Report and Literature Review. Am J Case Rep. 2021 Jan 16;22:e927761. doi: 10.12659/AJCR.927761. PMID: 33452231; PMCID: PMC7816826.1. journals2021
Andrew ChurgChapel DB, Schulte JJ, Absenger G, Attanoos R, Brcic L, Butnor KJ, Chirieac L, Churg A, Galateau-Sallé F, Hiroshima K, Hung YP, Kindler H, Krausz T, Marchevsky A, Mino-Kenudson M, Mueller J, Nabeshima K, Turaga K, Walts AE, Husain AN. Malignant peritoneal mesothelioma: prognostic significance of clinical and pathologic parameters and validation of a nuclear-grading system in a multi-institutional series of 225 cases. Mod Pathol. 2021 Feb;34(2):380-395. doi: 10.1038/s41379-020-00688-4. Epub 2020 Oct 15. PMID: 33060816.1. journals2021
Andrew ChurgChurg A, Wright JL. Morphologic Features of Fibrotic Hypersensitivity Pneumonitis in Transbronchial Cryobiopsies Versus Video-Assisted Thoracoscopic Biopsies: An In Silico Study. Arch Pathol Lab Med. 2021 Apr 1;145(4):448-452. doi: 10.5858/arpa.2020-0176-OA. PMID: 32886735.1. journals2021
Andrew ChurgRen HZ, Tessier-Cloutier B, Naso JR, Koebel M, Lee CH, Churg A. Pleural Malignant Mesotheliomas Do Not Demonstrate SWItch/Sucrose Nonfermentable (SWI/SNF) Complex Deficiency. Am J Surg Pathol. 2021 Feb 1;45(2):290-291. doi: 10.1097/PAS.0000000000001556. PMID: 32769432.1. journals2021
Andrew RothDominance of inter-patient variability in gene essentiality across primary triple negative breast cancers revealed by quantified CRISPR perturbation in vivo. Peter Eirew, Jerome Ting, Sohrab Salehi, Jazmine Brimhall, Jecy Wang, Justina Biele, Teresa Algara, So Ra Lee, Corey Hoang, Ciara O'Flanagan, Damian Yap, Steven McKinney, Cherie Bates, Esther Kong, Daniel Lai, Sean Beatty, Mirela Andronescu, Elena Zaikova, Tyler Funnell, Nicholas Ceglia, Stephen Chia, Karen Gelmon, Colin Mar, Sohrab Shah, Andrew Roth, Alexandre Bouchard, Samuel Aparicio. Nature Communications. Under review.1. journals2021
Andrew RothExpansion sequencing: Spatially precise in situ transcriptomics in intact biological systems.Science (New York, N.Y.). 371(6528). Alon, S; Goodwin, D; Sinha, A; Wassie, A; Chen, F; Daugharthy, E; Bando, Y; Kajita, A; Xue, A; Marrett, K; Prior, R; Cui, Y; Payne, A; Yao, C; Suk, H; Wang, R; Yu, C; Tillberg, P; Reginato, P; Pak, N; Liu, S; Punthambaker, S; Iyer, E; Kohman, R; Miller, J; Lein, E; Lako, A; Cullen, N; Rodig, S; Helvie, K; Abravanel, D; Wagle, N; Johnson, B; Klughammer, J; Slyper, M; Waldman, J; Jané-Valbuena, J; Rozenblatt-Rosen, O; Regev, A; IMAXT Consortium; Church, G; Marblestone, A; Boyden, E. (2021). 1. journals2021
Andrew Roth Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response.Nature communications. 12(1): 1998. Georgopoulou, D; Callari, M; Rueda, O; Shea, A; Martin, A; Giovannetti, A; Qosaj, F; Dariush, A; Chin, S; Carnevalli, L; Provenzano, E; Greenwood, W; Lerda, G; Esmaeilishirazifard, E; O'Reilly, M; Serra, V; Bressan, D; IMAXT Consortium; Mills, G; Ali, H; Cosulich, S; Hannon, G; Bruna, A; Caldas, C. March 2021.1. journals2021
Andrew RothParticle-Gibbs Sampling For Bayesian Feature Allocation Models. Journal of Machine Learning Research. Bouchard-Côté, A; Roth, A. Oct 2021. 1. journals2021
Andrew Roth Clonal fitness inferred from time-series modelling of single-cell cancer genomes.Nature. 595(7868): 585-590. Salehi, S; Kabeer, F; Ceglia, N; Andronescu, M; Williams, M; Campbell, K; Masud, T; Wang, B; Biele, J; Brimhall, J; Gee, D; Lee, H; Ting, J; Zhang, A; Tran, H; O'Flanagan, C; Dorri, F; Rusk, N; de, T; Lee, S; Cheng, B; Eirew, P; Kono, T; Pham, J; Grewal, D; Lai, D; Moore, R; Mungall, A; Marra, M; IMAXT Consortium; McPherson, A; Bouchard-Côté, A; Aparicio, S; Shah, S. June 2021.1. journals2021
Andrew WengTamiro F, Weng AP, Giambra V. Targeting Leukemia-Initiating Cells in Acute Lymphoblastic Leukemia. Cancer Res. 2021 Aug 15;81(16):4165-4173. doi: 10.1158/0008-5472.CAN-20-2571. Epub 2021 Jan 7. PMID: 33414170. CA1. journals2021
Andrew WengIslam R, Bilenky M, Weng AP, Connors JM, Hirst M. CRIS: complete reconstruction of immunoglobulin V-D-J sequences from RNA-seq data. Bioinform Adv. 2021 Sep 9;1(1):vbab021. doi: 10.1093/bioadv/vbab021. PMID: 34806017; PMCID: PMC8600631. CA1. journals2021
Andrew WengWong R, Nguyen A, Wang X, Chong L, Tyshchenko K, Brown SD, Holt RA, Steidl C, Weng AP. Improved resolution of phenotypic subsets in human T-ALL by incorporation of RNA-seq based developmental profiling. Leuk Res. 2021 Nov;110:106712 Epub 2021 Sep 22. PMID: 34583126. SA 1. journals2021
Arjun MehtaMehta A, Davey J, Wiedemeyer K, Brenn T. Morphologically high-grade trichoblastic carcinoma: a clinicopathological study with long-term clinical follow-up. Histopathology. 2021 Jun;78(7):970-975. doi: 10.1111/his.14325. Epub 2021 Apr 6. PMID: 33393120.1. journals2021
Audi SetiadiAl Moosawi, M., Vawda, A. & Setiadi, A. EDTA-induced platelet hypogranulation: beware of dysplasia mimic!. J Hematopathol 14, 183€“184 (2021).1. journals2021
Bradley CoeWilfert AB, Turner TN, Murali SC, Hsieh P, Sulovari A, Wang T, Coe BP, Guo H, Hoekzema K, Bakken TE, Winterkorn LH, Evani US, Byrska-Bishop M, Earl RK, Bernier RA; SPARK Consortium, Zody MC, Eichler EE. (2021) Recent ultra-rare inherited variants implicate new autism candidate risk genes. Nat Genet. 53(8):1125-1134.1. journals2021
Brian SkinniderFreeman CL, Savage KJ, Villa DR, Scott DW, Srour L, Gerrie AS, Brown MJ, Slack GW, Farinha P, Skinnider B, Morris J, Benard F, Aquino-Parsons C, Lo A, Pickles T, Wilson DC, Tonseth P, Connors JM, Sehn LH.  Long-term results of PET-guided radiation in patients with advanced-stage diffuse large B-cell lymphoma treated with R-CHOP.  Blood 2021 Feb 18; 137(7):929-938.1. journals2021
Bruce VerchereCefalu WT, Andersen DK, Arreaza-Rubín G, Pin CL, Sato S, Verchere CB, Woo M, Rosenblum ND; Symposium planning committee, moderators, and speakers:, Rosenblum N, Cefalu W, Andersen DK, Arreaza-Rubín G, Dhara C, James SP, Makarchuk MJ, Pin CL, Sato S, Verchere B, Woo M, Powers A, Estall J, Hoesli C, Millman J, Linnemann A, Johnson J, Pin CL, Hawkins M, Woo M, Gloyn A, Cefalu W, Rosenblum N, Huising MO, Benninger RKP, Almaça J, Hull-Meichle RL, MacDonald P, Lynn F, Melero-Martin J, Yoshihara E, Stabler C, Sander M, Evans-Molina C, Engin F, Thompson P, Shalev A, Redondo MJ, Nadeau K, Bellin M, Udler MS, Dennis J, Dash S, Zhou W, Snyder M, Booth G, Butte A, Florez J. Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases. Diabetes. 2021 Nov 13:db210777. doi: 10.2337/db21-0777. Epub ahead of print. PMID: 34957490.1. journals2021
Bruce VerchereCefalu WT, Andersen DK, Arreaza-Rubín G, Pin CL, Sato S, Verchere CB, Woo M, Rosenblum ND; symposium planning committee, moderators, and speakers. Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases. Can J Diabetes. 2021 Dec;45(8):697-713. doi: 10.1016/j.jcjd.2021.09.126. Epub 2021 Nov 15. PMID: 34794897.1. journals2021
Bruce VerchereCefalu WT, Andersen DK, Arreaza-Rubín G, Pin CL, Sato S, Verchere CB, Woo M, Rosenblum ND; symposium planning committee, moderators, and speakers; Symposium planning committee, moderators, and speakers:. Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases. Diabetes. 2021 Nov 15:db210777. doi: 10.2337/db21-0777. Epub ahead of print. PMID: 34782351.1. journals2021
Bruce VerchereBudd MA, Monajemi M, Colpitts SJ, Crome SQ, Verchere CB, Levings MK. Interactions between islets and regulatory immune cells in health and type 1 diabetes. Diabetologia. 2021 Nov;64(11):2378-2388. doi: 10.1007/s00125-021-05565-6. Epub 2021 Sep 22. PMID: 34550422.1. journals2021
Bruce VerchereKahn SE, Chen YC, Esser N, Taylor AJ, van Raalte DH, Zraika S, Verchere CB. The β Cell in Diabetes: Integrating Biomarkers With Functional Measures. Endocr Rev. 2021 Sep 28;42(5):528-583. doi: 10.1210/endrev/bnab021. PMID: 34180979.1. journals2021
Bruce VerchereRodriguez-Calvo T, Chen YC, Verchere CB, Haataja L, Arvan P, Leete P, Richardson SJ, Morgan NG, Qian WJ, Pugliese A, Atkinson M, Evans-Molina C, Sims EK. Altered β-Cell Prohormone Processing and Secretion in Type 1 Diabetes. Diabetes. 2021 May;70(5):1038-1050. doi: 10.2337/dbi20-0034. Epub 2021 May 4. PMID: 33947721; PMCID: PMC8173804.1. journals2021
Bruce VerchereShakya M, Gahlot S, White A, Verchere CB, Low MJ, Lindberg I. Mice lacking PC1/3 expression in POMC-expressing cells do not develop obesity. Endocrinology. 2021 Mar 10;162(6):bqab055. doi: 10.1210/endocr/bqab055. Epub ahead of print. PMID: 33693631; PMCID: PMC8253230.1. journals2021
Bruce VerchereDenroche HC, Miard S, Sallé-Lefort S, Picard F, Verchere CB. T cells accumulate in non-diabetic islets during ageing. Immun Ageing. 2021 Feb 23;18(1):8. doi: 10.1186/s12979-021-00221-4. PMID: 33622333; PMCID: PMC7901217.1. journals2021
Catherine HoganWang H, Hogan CA, Verghese M, Solis D, Sibai M, Huang C, Zehnder J, Sahoo MK, Pinsky BA. Ultra-sensitive Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigen Detection for the Diagnosis of Coronavirus Disease 2019 (COVID-19) in Upper Respiratory Samples. Clin Infect Dis. 2021 Apr 8:ciab063. doi: 10.1093/cid/ciab063. Epub ahead of print.1. journals2021
Catherine HoganStevens BA, Hogan CA, Mfuh KO, Khan G, Sahoo MK, Huang C, Garamani N, Zehnder J, Kurzer J, Pinsky BA. Combined SARS-CoV-2 nucleic acid amplification testing and respiratory virus panel RT-PCR on the Hologic Panther Fusion system. J Clin Virol. 2021 Mar 10;138:104792. doi: 10.1016/j.jcv.2021.104792. Epub ahead of print.1. journals2021
Catherine HoganBroadhurst MJ, Garamani N, Hahn Z, Jiang B, Weber J, Huang C, Sahoo MK, Kurzer J, Hogan CA, Pinsky BA. Evaluation of a measles virus multiplex, triple-target real-time RT-PCR in three specimen matrices at a U.S. academic medical center. J Clin Virol. 2021 Mar;136:104757.1. journals2021
Catherine HoganSenchyna F, Hogan CA, Murugesan K, Moreno A, Ho DY, Subramanian A, Schwenk HT, Budvytiene I, Costa HA, Gombar S, Banaei N. Clinical Accuracy and Impact of Plasma Cell-Free DNA Fungal PCR Panel for Non-Invasive Diagnosis of Fungal Infection. Clin Infect Dis. 2021 Feb 19:ciab158.1. journals2021
Catherine HoganLong DR, Gombar S, Hogan CA, Greninger AL, O'Reilly-Shah V, Bryson-Cahn C, Stevens B, Rustagi A, Jerome KR, Kong CS, Zehnder J, Shah NH, Weiss NS, Pinsky BA, Sunshine JE. Occurrence and Timing of Subsequent Severe Acute Respiratory Syndrome Coronavirus 2 Reverse-transcription Polymerase Chain Reaction Positivity Among Initially Negative Patients. Clin Infect Dis. 2021 Jan 27;72(2):323-326.1. journals2021
Catherine Hogan Hogan CA, Huang C, Sahoo MK, Wang H, Jiang B, Sibai M, Holubar M, Mathew R, Zehnder J, Pinsky BA. Strand-Specific Reverse Transcription PCR for Detection of Replicating SARS-CoV-2. Emerg Infect Dis. 2021 Feb;27(2):632-635.1. journals2021
Cheryl WellingtonCharacterization of Cerebrospinal Fluid Ubiquitin C-Terminal Hydrolase L1 (UCH-L1) as a Biomarker of Human Acute Traumatic Spinal Cord Injury. Stukas S, Gill J, Cooper J, Belanger L, Ritchie L, Tsang A, Dong K, Streijger F, Street J, Paquette S, Ailon T, Dea N, Charest-Morin R, Fisher CG, Dhall S, Mac-Thiong JM, Wilson JR, Bailey C, Christie S, Dvorak MF, Wellington C, Kwon BK.J Neurotrauma. 2021 May 3. doi: 10.1089/neu.2020.7352. Online ahead of print.1. journals2021
Cheryl WellingtonAssessing the importance of interleukin-6 in COVID-19. Chen LYC, Hoiland RL, Stukas S, Wellington CL, Sekhon MS. Lancet Respir Med. 2021 Feb;9(2):e13. doi: 10.1016/S2213-2600(20)30600-7. Epub 2021 Jan 15.1. journals2021
Cheryl WellingtonHoiland RL, Ainslie PN, Wellington CL, Cooper J, Stukas S, Thiara S, Foster D, Fergusson NA, Conway EM, Menon DK, Gooderham P, Hirsch-Reinshagen V, Griesdale DE, Sekhon MS. Brain Hypoxia Is Associated With Neuroglial Injury in Humans Post-Cardiac Arrest. Circ Res. 2021 Aug 20;129(5):583-597. doi: 10.1161/CIRCRESAHA.121.319157. Epub 2021 Jul 21. PMID: 34287000; PMCID: PMC8376277.1. journals2021
Cheryl WellingtonVavasour IM, Becquart P, Gill J, Zhao G, Yik JT, Traboulsee A, Carruthers RL, Kolind SH, Schabas AJ, Sayao AL, Devonshire V, Tam R, Moore GRW, Stukas S, Wellington CL, Quandt JA, Li DKB, Laule C. Diffusely abnormal white matter in clinically isolated syndrome is associated with parenchymal loss and elevated neurofilament levels. Mult Scler Relat Disord. 2021 Nov 26;57:103422. doi: 10.1016/j.msard.2021.103422. Epub ahead of print. PMID: 34871858.1. journals2021
Cheryl WellingtonDevelopment of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury. Button EB, Cheng WH, Barron C, Cheung H, Bashir A, Cooper J, Gill J, Stukas S, Baron DC, Robert J, Rowe EM, Cripton PA, Wellington CL. Alzheimers Res Ther. 2021 Mar 7;13(1):58. doi: 10.1186/s13195-021-00793-9.1. journals2021
Cheryl WellingtonReview of Design Considerations for Brain-on-a-Chip Models. Cameron T, Bennet T, Rowe EM, Anwer M, Wellington CL, Cheung KC. Micromachines (Basel). 2021 Apr 15;12(4):441. doi: 10.3390/mi12040441.1. journals2021
Cheryl WellingtonSoluble Interleukin-6 Receptor in the COVID-19 Cytokine Storm Syndrome. Chen LYC, Biggs CM, Jamal S, Stukas S, Wellington CL, Sekhon MS. Cell Rep Med. 2021 Apr 19:100269. doi: 10.1016/j.xcrm.2021.100269. Online ahead of print.1. journals2021
Cheryl WellingtonPersistently elevated complement alternative pathway biomarkers in COVID-19 correlate with hypoxemia and predict in-hospital mortality. Leatherdale A, Stukas S, Lei V, West H, Campbell CJ, Hoiland RL, Cooper J, Wellington CL, Sekhon MS, Pryzydial ELG, Conway EM. Medical Microbiology and Immunology. https://doi.org/10.1007/s00430-021-00725-2.1. journals2021
Cheryl WellingtonDiffusely abnormal white matter in clinically isolated syndrome is associated with parenchymal loss and elevated neurofilament levels. Vavasour IM, Becquart P, Gill J, Zhao G, Yik JT, Traboulsee A, Carruthers RL, Kolind SH, Schabas AJ, Sayao AL, Devonshire V, Tam R, Moore GRW, Stukas S, Wellington CL, Quandt JA, Li DKB, Laule C. Mult Scler Relat Disord. 2021 Nov 26;57:103422. doi: 10.1016/j.msard.2021.103422. Online ahead of print.PMID: 34871858 Review.1. journals2021
Cheryl WellingtonBlood-based traumatic brain injury biomarkers - Clinical utilities and regulatory pathways in the United States, Europe and Canada.Wang KK, Munoz Pareja JC, Mondello S, Diaz-Arrastia R, Wellington C, Kenney K, Puccio AM, Hutchison J, McKinnon N, Okonkwo DO, Yang Z, Kobeissy F, Tyndall JA, Büki A, Czeiter E, Pareja Zabala MC, Gandham N, Berman R; and the InTBIR Biospecimens/Biomarkers Working Group. Expert Rev Mol Diagn. 2021 Dec;21(12):1303-1321. doi: 10.1080/14737159.2021.2005583. Epub 2021 Nov 29.PMID: 347832741. journals2021
Cheryl WellingtonBrain Hypoxia Is Associated With Neuroglial Injury in Humans Post-Cardiac Arrest. Hoiland RL, Ainslie PN, Wellington CL, Cooper J, Stukas S, Thiara S, Foster D, Fergusson NA, Conway EM, Menon DK, Gooderham P, Hirsch-Reinshagen V, Griesdale DE, Sekhon MS. Circ Res. 2021 Aug 20;129(5):583-597. doi: 10.1161/CIRCRESAHA.121.319157. Epub 2021 Jul 21.PMID: 34287000 1. journals2021
Cheryl WellingtonRed blood cell transfusion in animal models of acute brain injuries: a systematic review protocol. Laflamme M, Haghbayan H, Lalu MM, Zarychanski R, Lauzier F, Boutin A, Macleod MR, Fergusson DA, Moore L, Costerousse O, Lacroix J, Wellington C, Hutchison J, Turgeon AF; Canadian Traumatic Brain Injury Research Consortium. Syst Rev. 2021 Jun 14;10(1):177. doi: 10.1186/s13643-021-01703-8.PMID: 34127055 1. journals2021
Christian Steidl[CA] Svoboda J, Bair SM, Landsburg DJ, Nasta SD, Nagle SJ, Barta SK, Khan N, Filicko-O'Hara J, Gaballa S, Strelec L, Chong E, Mitnick S, Waite TS, King C, Ballard H, Youngman M, Gerson J, Plastaras JP, Maity A, Bogusz AM, Hung SS, Nakamura H, Nejati R, Steidl C, Lim M, Ruella M, Schuster SJ. Brentuximab vedotin in combination with rituximab, cyclophosphamide, doxorubicin, and prednisone as frontline treatment for patients with CD30-positive B-cell lymphomas. Haematologica. 2021 Jun 1;106(6):1705-1713. doi: 10.3324/haematol.2019.238675. PMID: 324148501. journals2021
Christian Steidl[CA] Twa DDW, Lee DG, Tan KL, Slack GW, Ben-Neriah S, Villa D, Connors JM, Sehn LH, Mottok A, Gascoyne RD, Scott DW, Steidl C, Savage KJ. Genomic predictors of central nervous system relapse in primary testicular diffuse large B-cell lymphoma (DLBCL). Blood. 2021 Mar 4;137(9):1256-1259. doi: 10.1182/blood.2020006338. PMID: 329670071. journals2021
Christian Steidl[CA] Sarkozy C, Hung SS, Chavez EA, Duns G, Takata K, Chong LC, Aoki T, Jiang A, Miyata-Takata T, Telenius A, Slack GW, Molina TJ, Ben-Neriah S, Farinha P, Dartigues P, Damotte D, Mottok A, Salles GA, Casasnovas RO, Savage KJ, Laurent C, Scott DW, Traverse-Glehen A, Steidl C. Mutational Landscape of Grey Zone Lymphoma. Blood. 2021 Apr 1;137(13):1765-1776. doi: 10.1182/blood.2020007507. PMID: 329615521. journals2021
Christian Steidl[CA] Isaev K, Ennishi D, Hilton L, Skinnider B, Mungall KL, Mungall AJ, Bakhtiari M, Tremblay-LeMay R, Silva A, Ben-Neriah S, Boyle M, Villa D, Marra MA, Steidl C, Gascoyne RD, Morin R, Savage KJ, Scott DW, Kridel R. Molecular Attributes Underlying Central Nervous System and Systemic Relapse in Diffuse Large B-cell Lymphoma. Haematologica. 2021 May 1;106(5):1466-1471. doi: 10.3324/haematol.2020.255950. PMID: 328172921. journals2021
Christian Steidl[CA] Collinge BJ, Ben-Neriah S, Chong LC, Boyle M, Jiang A, Miyata-Takata T, Farinha P, Craig JW, Slack GW, Ennishi D, Mottok A, Meissner B, Chavez EA, Gerrie AS, Villa D, Freeman CL, Savage KJ, Sehn LH, Morin RD, Mungall AJ, Gascoyne RD, Marra MA, Connors JM, Steidl C, Scott DW. Impact of MYC and BCL2 structural variants in tumors of DLBCL morphology and mechanisms of false-negative MYC IHC. Blood. 2021 Apr 22;137(16):2196-2208. doi: 10.1182/blood.2020007193. PMID: 331204271. journals2021
Christian Steidl[SA] Aoki T, Savage KJ, Steidl C. Biology in Practice: Harnessing the Curative Potential of the Immune System in Lymphoid Cancers. J Clin Oncol. 2021 Feb 10;39(5):346-360. doi: 10.1200/JCO.20.01761. Epub 2021 Jan 12. PMID: 33434057.1. journals2021
Christian Steidl[CA] Rys RN, Wever CM, Geoffrion D, Goncalves C, Ghassemian A, Brailovski E, Ryan J, Stoica L, Hébert J, Petrogiannis-Haliotis T, Dmitrienko S, Frenkiel S, Staiger A, Ott G, Steidl C, Scott DW, Sesques P, Del Rincon S, Mann KK, Letai A, Johnson NA. Apoptotic Blocks in Primary Non-Hodgkin B Cell Lymphomas Identified by BH3 Profiling. Cancers (Basel). 2021 Feb 28;13(5):1002. doi: 10.3390/cancers13051002. PMID: 33670870; PMCID: PMC7957722.1. journals2021
Christian Steidl[SA] Duns G, Viganò E, Ennishi D, Sarkozy C, Hung SS, Chavez EA, Takata K, Rushton C, Jiang A, Ben-Neriah S, Woolcock B, Slack GW, Hsi ED, Craig JW, Hilton LK, Shah S, Farinha P, Mottok A, Gascoyne RD, Morin RD, Savage KJ, Scott DW, Steidl C. Characterization of DLBCL with a PMBL gene expression signature. Blood. 2021 Jul 15;138(2):136-148. doi: 10.1182/blood.2020007683. PMID: 336849391. journals2021
Christian Steidl[CA] Nikiforuk AM, Kuchinski KS, Twa DDW, Lukac CD, Sbihi H, Basham CA, Steidl C, Prystajecky NA, Jassem AN, Krajden M, Patrick DM, Sekirov I. The contrasting role of nasopharyngeal angiotensin converting enzyme 2 (ACE2) transcription in SARS-CoV-2 infection: A cross-sectional study of people tested for COVID-19 in British Columbia, Canada. EBioMedicine. 2021 Apr;66:103316. doi: 10.1016/j.ebiom.2021.103316. Epub 2021 Apr 2. PMID: 33819740; PMCID: PMC8016616.1. journals2021
Christian Steidl[CA] Laumont CM, Wouters MCA, Smazynski J, Gierc NS, Chavez EA, Chong LC, Thornton S, Milne K, Webb JR, Steidl C, Nelson BH. Single-cell Profiles and Prognostic Impact of Tumor-Infiltrating Lymphocytes Coexpressing CD39, CD103, and PD-1 in Ovarian Cancer. Clin Cancer Res. 2021 Jul 15;27(14):4089-4100. doi: 10.1158/1078-0432.CCR-20-4394. Epub 2021 May 7.1. journals2021
Christian Steidl[CA] Jachimowicz RD, Klapper W, Glehr G, Müller H, Haverkamp H, Thorns C, Hansmann ML, Möller P, Stein H, Rehberg T, von Tresckow B, Reinhardt HC, Borchmann P, Chan FC, Spang R, Scott DW, Engert A, Steidl C, Altenbuchinger M, Rosenwald A. Gene expression-based outcome prediction in advanced stage classical Hodgkin lymphoma treated with BEACOPP. Leukemia. 2021 Jun 10. doi: 10.1038/s41375-021-01314-1. Online ahead of print.1. journals2021
Christian Steidl[CA] Tong KI, Yoon S, Isaev K, Bakhtiari M, Lackraj T, He MY, Joynt J, Silva A, Xu MC, Privé GG, He HH, Tiedemann RE, Chavez EA, Chong LC, Boyle M, Scott DW, Steidl C, Kridel R. Combined EZH2 Inhibition and IKAROS Degradation Leads to Enhanced Antitumor Activity in Diffuse Large B-cell Lymphoma. Clin Cancer Res. 2021 Jun 24. doi: 10.1158/1078-0432.CCR-20-4027. Online ahead of print.1. journals2021
Christian Steidl[CA] Wong R, Nguyen A, Wang X, Chong L, Tyshchenko K, Brown SD, Holt RA, Steidl C, Weng AP. Improved resolution of phenotypic subsets in human T-ALL by incorporation of RNA-seq based developmental profiling. Leuk Res. 2021 Sep 22;110:106712. doi: 10.1016/j.leukres.2021.106712. Online ahead of print.1. journals2021
Christian Steidl[SA] Aoki T, Chong LC, Takata K, Milne K, Marshall A, Chavez EA, Miyata-Takata T, Ben-Neriah S, Unrau D, Telenius A, Boyle M, Weng AP, Savage KJ, Scott DW, Farinha P, Shah SP, Nelson BH, Steidl C. Single-cell profiling reveals the importance of CXCL13/CXCR5 axis biology in lymphocyte-rich classic Hodgkin lymphoma. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2105822118. doi: 10.1073/pnas.2105822118.1. journals2021
Christian Steidl[SA] Johnston RL, Mottok A, Chan FC, Jiang A, Diepstra A, Visser L, Telenius A, Gascoyne RD, Friedman DL, Schwartz CL, Kelly K, Scott DW, Horton TM, Steidl C. Gene expression-based model predicts outcome in children with intermediate-risk classical Hodgkin lymphoma. Blood. 2021 Oct 18; blood.2021011941. doi: 10.1182/blood.2021011941. Online ahead of print.1. journals2021
Christian Steidl[CA] Patel N, Slack GW, Bodo J, Ben-Neriah S, Villa D, Durkin L, Socha D, Steidl C, Hsi ED. Immune Escape Mechanisms in Intravascular Large B-Cell Lymphoma. Am J Clin Pathol. 2021 Nov 1:aqab154. doi: 10.1093/ajcp/aqab154. Epub ahead of print. PMID: 34724028.1. journals2021
Christian Steidl[CA] Karihtala K, Leivonen SK, Karjalainen-Lindsberg ML, Chan FC, Steidl C, Pellinen T, Leppa S. Checkpoint protein expression in the tumor microenvironment defines the outcome of classical Hodgkin lymphoma patients. Blood Adv. 2021 Dec 23:bloodadvances.2021006189. doi: 10.1182/bloodadvances.2021006189. Online ahead of print. PMID: 349419901. journals2021
Christine CollierHiggins V, White-Al Habeeb N, Venner AA, Bailey D, Collier C, Adeli K.(On behalf of the Canadian Society of Clinical Chemists (CSCC) Working Group on Reference Interval Harmonization) A Snapshot of Lipid Reporting Practices in Canadian Clinical Laboratories: An Urgent Need for Harmonization. 2021; Can J Cardiol 25;S0828-282X(21)00167-7.1. journals2021
Christine CollierWhite CA, Sarabia S, Collier CP, McCudden C, Holden RM. Parathyroid hormone measurement in chronic kidney disease: Impact of inter-method variability on mineral bone disease assessment. Clin Biochem. 2021 Aug;94:62-66. doi: 10.1016/j.clinbiochem.2021.04.018. Epub 2021 Apr 23. PMID: 33895125.1. journals2021
Christopher LoweBedi H, Chahal D, Lowe CF, Ritchie G, Hussaini T, Marquez V, Yoshida EM. 2021. Occult hepatitis B reactivation after liver transplant: the role of a novel mutation in the surface antigen.  J Clin Transl Hepatol. 9(1):136-138. CA1. journals2021
Christopher LoweLowe CF, Kiaii M, Aparicio L, Chinybaeva L, Coughlin S, Sekirov I, Mohammed M, Leung V. 2021. Risk following a SARS-CoV-2 exposure from a nocturnal hemodialysis patient utilizing continuous positive airway pressure (CPAP).  Infect Control Hosp Epidemiol. 42: 491€“492. https://doi.org/10.1017/ice.2020.291. FA1. journals2021
Christopher LoweMatic N, Lawson T, Ritchie G, Stefanovic A, Leung V, Champagne S, Romney MG, Lowe CF. 2021.  Automated molecular testing of saliva for SARS-CoV-2 detection.  Diagn Microbiol Infect Dis. 100(1):115324. doi: 10.1016/j.diagmicrobio.2021.115324.  SA1. journals2021
Christopher LoweMatic N*, Lowe CF*, Ritchie G, Stefanovic A, Lawson T, Jang W, Young M, Dong W, Brumme ZL, Brumme CJ, Leung V, Romney MG. 2021. Rapid detection of SARS-CoV-2 variants of concern, including B.1.1.28/P.1, in British Columbia, Canada. Emerg Infect Dis. 27(6). https://doi.org/10.3201/eid2706.210532. FA1. journals2021
Christopher LoweCojocaru R, Yaseen I, Unrau PJ, Lowe CF, Ritchie G, Romney MG, Sin DD, Gill S, Slyadnev M. 2021. Microchip RT-PCR Detection of Nasopharyngeal SARS-CoV-2 Samples. J Mol Diagn. S1525-1578(21)00063-5. doi: 10.1016/j.jmoldx.2021.02.009. CA1. journals2021
Christopher LoweKinloch NN, Ritchie G, Dong W, Cobarrubias KD, Sudderuddin H, Lawson T, Montaner JSG, Leung V, Romney MG, Lowe CF, Brumme CJ, Brumme ZB.  2021. SARS-CoV-2 RNA quantification using droplet digital RT-PCR.  J Mol Diagn. S1525-1578(21)00136-7. CA1. journals2021
Christopher LoweChorlton SD, Ritchie G, Lawson T, McLachlan E, Romney MG, Matic N, Lowe CF. 2021. Next-generation sequencing for cytomegalovirus antiviral resistance genotyping in a clinical virology laboratory.  Antiviral Res. 192:105123. SA1. journals2021
Christopher LoweReich N, Lowe CF, Puddicombe D, Matic N, Greiner J, Simons J, Leung V, Chu T, Naik H, Myles N, Burns L, Romney MG, Ritchie G, Champagne S, Dooley K, Sekirov I, Stefanovic A. 2021. Repeat virological and serological profiles in hospitalized patients initially tested by nasopharyngeal RT-PCR for SARS-CoV-2. J Med Virol. doi: 10.1002/jmv.27227. CA1. journals2021
Christopher LoweBedi HK, Trasolini R, Lowe CF, Hussaini T, Bigham M, Ritchie G, Yoshida EM. 2021. De novo hepatitis B surface antigen (HBsAg) positive, core antibody (Anti-HBc) negative, hepatitis B virus infection post-liver transplant from an anti-HBc, HBsAg negative donor. Hepatology Forum. 3(2): 117-119. CA1. journals2021
Christopher LoweGreninger A, Bard JD, Colgrove R, Graf E, Hanson K, Hayden M, Humphries R, Lowe CF, Miller M, Pillai D, Rhoads D, Yao J, Lee F. Clinical Applications of SARS-CoV-2 Genotyping: An IDSA/ASM Consensus Review Document. J Clin Microbiol. https://doi.org/10.1128/JCM.01659-21. CA1. journals2021
Christopher LoweGreninger A, Bard JD, Colgrove R, Graf E, Hanson K, Hayden M, Humphries R, Lowe CF, Miller M, Pillai D, Rhoads D, Yao J, Lee F. 2021. Clinical Applications of SARS-CoV-2 Genotyping: An IDSA/ASM Consensus Review Document. Clin Infect Dis. https://doi.org/10.1093/cid/ciab761. CA1. journals2021
Christopher HughesZhang HF, Hughes CS, Li W, He JZ, Surdez D, El-Naggar AM, Cheng H, Prudova A, Delaidelli A, Negri GL, Li X, Ørum-Madsen MS, Lizardo MM, Oo HZ, Colborne S, Shyp T, Scopim-Ribeiro R, Hammond CA, Dhez AC, Langman S, Lim JKM, Kung SHY, Li A, Steino A, Daugaard M, Parker SJ, Geltink RIK, Orentas RJ, Xu LY, Morin GB, Delattre O, Dimitrov DS, Sorensen PH. Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma. Cancer Discov. 2021 Nov;11(11):2884-2903. doi: 10.1158/2159-8290.CD-20-1690. Epub 2021 May 21. PMID: 34021002; PMCID: PMC8563374.1. journals2021
Christopher HughesTurgu B, Zhang F, El-Naggar A, Negri GL, Kogler M, Tortola L, Johnson F, Ng T, Li A, Yapp D, Lockwood W, Martinez D, Maris JM, Daugaard M, Penninger JM, Hughes CS, Sorensen PH. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner. Oncogene. 2021 Mar;40(11):1988-2001. doi: 10.1038/s41388-021-01680-1. Epub 2021 Feb 18. PMID: 33603169; PMCID: PMC7979542.1. journals2021
Christopher HughesAllen GE, Panasenko OO, Villanyi Z, Zagatti M, Weiss B, Pagliazzo L, Huch S, Polte C, Zahoran S, Hughes CS, Pelechano V, Ignatova Z, Collart MA. Not4 and Not5 modulate translation elongation by Rps7A ubiquitination, Rli1 moonlighting, and condensates that exclude eIF5A. Cell Rep. 2021 Aug 31;36(9):109633. doi: 10.1016/j.celrep.2021.109633. PMID: 34469733.1. journals2021
Chun SeowWang L, Chitano P, Seow CY. Filament evanescence of myosin II and smooth muscle function. J Gen Physiol. 2021 Mar 1;153(3):e202012781.1. journals2021
Chun SeowDong SJ, Wang L, Chitano P, Coxson HO, Paré PD, Seow CY. Airway diameter at different transpulmonary pressures in ex vivo sheep lungs: implications for deep inspiration-induced bronchodilation and bronchoprotection. Am J Physiol Lung Cell Mol Physiol. 2021 Oct 1;321(4):L663-L674. doi: 10.1152/ajplung.00208.2021. Epub 2021 Jul 21. PMID: 34287071.1. journals2021
Chun SeowBourke, J., Ammit, A., Burgess, J., Gosens, R., Halayko, A., Seow, C., Hirst, S. Smooth muscle cells. In: Janes, S.M. (Ed.), Encyclopedia of Respiratory Medicine, vol. 1. Elsevier, Academic Press, pp. 37€“51, 2021. https://dx.doi.org/10.1016/B978-0-08-102723-3.00239-0.1. journals2021
Clayton MacDonaldKanji JN, Zelyas N, MacDonald C, Pabbaraju K, Khan MN, Prasad A, Hu J, Diggle M, Berenger BM, Tipples G. False negative rate of COVID-19 PCR testing: a discordant testing analysis. Virol J. 2021 Jan 9;18(1):13. doi: 10.1186/s12985-021-01489-0. PMID: 33422083; PMCID: PMC7794619.1. journals2021
Clayton MacDonaldBelga S, MacDonald C, Chiang D, Kabbani D, Shojai S, Abraldes JG, Cervera C. Donor Graft Cytomegalovirus Serostatus and the Risk of Arterial and Venous Thrombotic Events in Seronegative Recipients After Non-Thoracic Solid Organ Transplantation. Clin Infect Dis. 2021 Mar 1;72(5):845-852. doi: 10.1093/cid/ciaa125. PMID: 32025704.1. journals2021
Clayton MacDonaldKanji JN, Bailey A, Fenton J, Robbin Lindsay L, Dibernardo A, Toledo NP, Waitt B, Lecocq N, Osiowy C, Giles E, Day J, Stokes W, MacDonald C, Turnbull L, Charlton C. Stability of SARS-CoV-2 IgG in multiple laboratory conditions and blood sample types. J Clin Virol. 2021 Jul 25;142:104933. doi: 10.1016/j.jcv.2021.104933. Epub ahead of print. PMID: 34364133; PMCID: PMC8310571.1. journals2021
Clayton MacDonaldHouston S, Belga S, Buttenschoen K, Cooper R, Girgis S, Gottstein B, Low G, Massolo A, MacDonald C, Müller N, Preiksaitis J, Sarlieve P, Vaughan S, Kowalewska-Grochowska K. Epidemiological and Clinical Characteristics of Alveolar Echinococcosis: An Emerging Infectious Disease in Alberta, Canada. Am J Trop Med Hyg. 2021 Mar 22;104(5):1863€“9. doi: 10.4269/ajtmh.20-1577. Epub ahead of print. PMID: 33755579; PMCID: PMC8103444.1. journals2021
Cornelia LauleKamma E, Becquart P, Traboulsee A, Schabas A, Vavasour IM, Laule C, Vilariño-Güell C, Quandt JA. Elevated levels of serum CD5 antigen-like protein distinguish secondary progressive multiple sclerosis from other disease subtypes. Mult Scler Relat Disord. 2021 Nov;56:103269. doi: 10.1016/j.msard.2021.103269. Epub 2021 Sep 20. PMID: 34638097.1. journals2021
Cornelia LauleCohen-Adad J, Alonso-Ortiz E, Abramovic M, Arneitz C, Atcheson N, Barlow L, Barry RL, Barth M, Battiston M, Büchel C, Budde M, Callot V, Combes AJE, De Leener B, Descoteaux M, de Sousa PL, Dostál M, Doyon J, Dvorak A, Eippert F, Epperson KR, Epperson KS, Freund P, Finsterbusch J, Foias A, Fratini M, Fukunaga I, Gandini Wheeler-Kingshott CAM, Germani G, Gilbert G, Giove F, Gros C, Grussu F, Hagiwara A, Henry PG, Horák T, Hori M, Joers J, Kamiya K, Karbasforoushan H, Keřkovský M, Khatibi A, Kim JW, Kinany N, Kitzler HH, Kolind S, Kong Y, Kudlička P, Kuntke P, Kurniawan ND, Kusmia S, Labounek R, Laganà MM, Laule C, Law CS, Lenglet C, Leutritz T, Liu Y, Llufriu S, Mackey S, Martinez-Heras E, Mattera L, Nestrasil I, O'Grady KP, Papinutto N, Papp D, Pareto D, Parrish TB, Pichiecchio A, Prados F, Rovira À, Ruitenberg MJ, Samson RS, Savini G, Seif M, Seifert AC, Smith AK, Smith SA, Smith ZA, Solana E, Suzuki Y, Tackley G, Tinnermann A, Valošek J, Van De Ville D, Yiannakas MC, Weber Ii KA, Weiskopf N, Wise RG, Wyss PO, Xu J. Author Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers. Sci Data. 2021 Sep 23;8(1):251. doi: 10.1038/s41597-021-01044-0. Erratum for: Sci Data. 2021 Aug 16;8(1):219. PMID: 34556662; PMCID: PMC8460649.1. journals2021
Cornelia LauleCohen-Adad J, Alonso-Ortiz E, Abramovic M, Arneitz C, Atcheson N, Barlow L, Barry RL, Barth M, Battiston M, Büchel C, Budde M, Callot V, Combes AJE, De Leener B, Descoteaux M, de Sousa PL, Dostál M, Doyon J, Dvorak A, Eippert F, Epperson KR, Epperson KS, Freund P, Finsterbusch J, Foias A, Fratini M, Fukunaga I, Gandini Wheeler-Kingshott CAM, Germani G, Gilbert G, Giove F, Gros C, Grussu F, Hagiwara A, Henry PG, Horák T, Hori M, Joers J, Kamiya K, Karbasforoushan H, Keřkovský M, Khatibi A, Kim JW, Kinany N, Kitzler HH, Kolind S, Kong Y, Kudlička P, Kuntke P, Kurniawan ND, Kusmia S, Labounek R, Laganà MM, Laule C, Law CS, Lenglet C, Leutritz T, Liu Y, Llufriu S, Mackey S, Martinez-Heras E, Mattera L, Nestrasil I, O'Grady KP, Papinutto N, Papp D, Pareto D, Parrish TB, Pichiecchio A, Prados F, Rovira À, Ruitenberg MJ, Samson RS, Savini G, Seif M, Seifert AC, Smith AK, Smith SA, Smith ZA, Solana E, Suzuki Y, Tackley G, Tinnermann A, Valošek J, Van De Ville D, Yiannakas MC, Weber Ii KA, Weiskopf N, Wise RG, Wyss PO, Xu J. Author Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers. Sci Data. 2021 Sep 10;8(1):242. doi: 10.1038/s41597-021-01026-2. Erratum for: Sci Data. 2021 Aug 16;8(1):219. PMID: 34508107; PMCID: PMC8433197.1. journals2021
Cornelia LauleCohen-Adad J, Alonso-Ortiz E, Abramovic M, Arneitz C, Atcheson N, Barlow L, Barry RL, Barth M, Battiston M, Büchel C, Budde M, Callot V, Combes AJE, De Leener B, Descoteaux M, de Sousa PL, Dostál M, Doyon J, Dvorak A, Eippert F, Epperson KR, Epperson KS, Freund P, Finsterbusch J, Foias A, Fratini M, Fukunaga I, Wheeler-Kingshott CAMG, Germani G, Gilbert G, Giove F, Gros C, Grussu F, Hagiwara A, Henry PG, Horák T, Hori M, Joers J, Kamiya K, Karbasforoushan H, Keřkovský M, Khatibi A, Kim JW, Kinany N, Kitzler H, Kolind S, Kong Y, Kudlička P, Kuntke P, Kurniawan ND, Kusmia S, Labounek R, Laganà MM, Laule C, Law CS, Lenglet C, Leutritz T, Liu Y, Llufriu S, Mackey S, Martinez-Heras E, Mattera L, Nestrasil I, O'Grady KP, Papinutto N, Papp D, Pareto D, Parrish TB, Pichiecchio A, Prados F, Rovira À, Ruitenberg MJ, Samson RS, Savini G, Seif M, Seifert AC, Smith AK, Smith SA, Smith ZA, Solana E, Suzuki Y, Tackley G, Tinnermann A, Valošek J, Van De Ville D, Yiannakas MC, Weber KA 2nd, Weiskopf N, Wise RG, Wyss PO, Xu J. Generic acquisition protocol for quantitative MRI of the spinal cord. Nat Protoc. 2021 Oct;16(10):4611-4632. doi: 10.1038/s41596-021-00588-0. Epub 2021 Aug 16. PMID: 34400839; PMCID: PMC8811488.1. journals2021
Cornelia LauleCohen-Adad J, Alonso-Ortiz E, Abramovic M, Arneitz C, Atcheson N, Barlow L, Barry RL, Barth M, Battiston M, Büchel C, Budde M, Callot V, Combes AJE, De Leener B, Descoteaux M, de Sousa PL, Dostál M, Doyon J, Dvorak A, Eippert F, Epperson KR, Epperson KS, Freund P, Finsterbusch J, Foias A, Fratini M, Fukunaga I, Gandini Wheeler-Kingshott CAM, Germani G, Gilbert G, Giove F, Gros C, Grussu F, Hagiwara A, Henry PG, Horák T, Hori M, Joers J, Kamiya K, Karbasforoushan H, Keřkovský M, Khatibi A, Kim JW, Kinany N, Kitzler HH, Kolind S, Kong Y, Kudlička P, Kuntke P, Kurniawan ND, Kusmia S, Labounek R, Laganà MM, Laule C, Law CS, Lenglet C, Leutritz T, Liu Y, Llufriu S, Mackey S, Martinez-Heras E, Mattera L, Nestrasil I, O'Grady KP, Papinutto N, Papp D, Pareto D, Parrish TB, Pichiecchio A, Prados F, Rovira À, Ruitenberg MJ, Samson RS, Savini G, Seif M, Seifert AC, Smith AK, Smith SA, Smith ZA, Solana E, Suzuki Y, Tackley G, Tinnermann A, Valošek J, Van De Ville D, Yiannakas MC, Weber Ii KA, Weiskopf N, Wise RG, Wyss PO, Xu J. Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers. Sci Data. 2021 Aug 16;8(1):219. doi: 10.1038/s41597-021-00941-8. Erratum in: Sci Data. 2021 Sep 10;8(1):242. Erratum in: Sci Data. 2021 Sep 23;8(1):251. PMID: 34400655; PMCID: PMC8368310.1. journals2021
Cornelia LauleVavasour IM, Chang KL, Combes AJE, Meyers SM, Kolind SH, Rauscher A, Li DKB, Traboulsee A, MacKay AL, Laule C. Water content changes in new multiple sclerosis lesions have a minimal effect on the determination of myelin water fraction values. J Neuroimaging. 2021 Nov;31(6):1119-1125. doi: 10.1111/jon.12908. Epub 2021 Jul 26. PMID: 34310789.1. journals2021
Cornelia LauleVavasour IM, Sun P, Graf C, Yik JT, Kolind SH, Li DK, Tam R, Sayao AL, Schabas A, Devonshire V, Carruthers R, Traboulsee A, Moore GW, Song SK, Laule C. Characterization of multiple sclerosis neuroinflammation and neurodegeneration with relaxation and diffusion basis spectrum imaging. Mult Scler. 2021 Jun 16:13524585211023345. doi: 10.1177/13524585211023345. Epub ahead of print. PMID: 34132126.1. journals2021
Cornelia LauleHolmes RD, Vavasour IM, Greenfield J, Zhao G, Lee JS, Moore GRW, Tam R, Metz LM, Trablousee A, Li DKB, Laule C. Nonlesional diffusely abnormal appearing white matter in clinically isolated syndrome: Prevalence, association with clinical and MRI features, and risk for conversion to multiple sclerosis. J Neuroimaging. 2021 Sep;31(5):981-994. doi: 10.1111/jon.12900. Epub 2021 Jun 15. PMID: 34128576.1. journals2021
Cornelia LaulePrevost VH, Yung A, Morris SR, Vavasour IM, Samadi-Bahrami Z, Moore GRW, Laule C, Mackay A, Kozlowski P. Temperature dependence and histological correlation of inhomogeneous magnetization transfer and myelin water imaging in ex vivo brain. Neuroimage. 2021 Aug 1;236:118046. doi: 10.1016/j.neuroimage.2021.118046. Epub 2021 Apr 20. PMID: 33848620.1. journals2021
Cornelia LauleLee LE, Vavasour IM, Dvorak A, Liu H, Abel S, Johnson P, Ristow S, Au S, Laule C, Tam R, Li DK, Cross H, Ackermans N, Schabas AJ, Chan J, Sayao AL, Devonshire V, Carruthers R, Traboulsee A, Kolind S. Cervical cord myelin abnormality is associated with clinical disability in multiple sclerosis. Mult Scler. 2021 Dec;27(14):2191-2198. doi: 10.1177/13524585211001780. Epub 2021 Mar 22. PMID: 33749378; PMCID: PMC8597183.1. journals2021
Cornelia LauleDao E, Tam R, Hsiung GR, Ten Brinke L, Crockett R, Barha CK, Yoo Y, Al Keridy W, Doherty SH, Laule C, MacKay AL, Liu-Ambrose T. Exploring the Contribution of Myelin Content in Normal Appearing White Matter to Cognitive Outcomes in Cerebral Small Vessel Disease. J Alzheimers Dis. 2021;80(1):91-101. doi: 10.3233/JAD-201134. PMID: 33523006.1. journals2021
Cornelia LauleDvorak AV, Swift-LaPointe T, Vavasour IM, Lee LE, Abel S, Russell-Schulz B, Graf C, Wurl A, Liu H, Laule C, Li DKB, Traboulsee A, Tam R, Boyd LA, MacKay AL, Kolind SH. An atlas for human brain myelin content throughout the adult life span. Sci Rep. 2021 Jan 11;11(1):269. doi: 10.1038/s41598-020-79540-3. PMID: 33431990; PMCID: PMC7801525.1. journals2021
Dana DevineMa Y, Hadjesfandiari N, Doschak M, Devine D, Tonelli M, Unsworth L. Peptide-Modified Surfaces for Binding Carbamylated Proteins from Plasma. Langmuir. 2021 Oct 26;37(42):12335-12345. doi: 10.1021/acs.langmuir.1c01783. Epub 2021 Oct 13. PMID: 34644097.1. journals2021
Dana DevineWendel S, Land K, Devine DV, Daly J, Bazin R, Tiberghien P, Lee CK, Arora S, Patidar GK, Khillan K, Smid WM, Vrielink H, Oreh A, Al-Riyami AZ, Hindawi S, Vermeulen M, Louw V, Burnouf T, Bloch EM, Goel R, Townsend M, So-Osman C. Lessons learned in the collection of convalescent plasma during the COVID-19 pandemic. Vox Sang. 2021 Sep;116(8):872-879. doi: 10.1111/vox.13096. Epub 2021 Mar 27. PMID: 33772791; PMCID: PMC8250874.1. journals2021
Dana DevineArbaeen AF, Schubert P, Sheffield WP, Devine DV. Pathogen reduction of whole blood: Supplementing fibrinogen partly corrects clot formation in a massive transfusion model. Transfusion. 2021 Mar 21. doi: 10.1111/trf.16382. Epub ahead of print. PMID: 33745131.1. journals2021
Dana DevineDrews SJ, Devine DV, McManus J, Mendoza E, Manguiat K, Wood H, Girardin R, Dupuis A, McDonough K, Drebot M. A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors. Transfusion. 2021 May;61(5):1440-1446. doi: 10.1111/trf.16364. Epub 2021 Mar 18. PMID: 33734448.1. journals2021
Dana DevineSchubert P, Culibrk L, Culibrk B, Conway EM, Goodrich RP, Devine DV. Releasates of riboflavin/UV-treated platelets: Microvesicles suppress cytokine-mediated endothelial cell migration/proliferation. Transfusion. 2021 May;61(5):1551-1561. doi: 10.1111/trf.16337. Epub 2021 Feb 24. PMID: 33629371.1. journals2021
Dana DevineGoel R, Bloch EM, Pirenne F, Al-Riyami AZ, Crowe E, Dau L, Land K, Townsend M, Jecko T, Rahimi-Levene N, Patidar G, Josephson CD, Arora S, Vermeulen M, Vrielink H, Montemayor C, Oreh A, Hindawi S, van den Berg K, Serrano K, So-Osman C, Wood E, Devine DV, Spitalnik SL; ISBT COVID-19 Working Group. ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 Working Group. Vox Sang. 2021 Sep;116(8):849-861. doi: 10.1111/vox.13076. Epub 2021 Feb 12. PMID: 33578447; PMCID: PMC8014128.1. journals2021
Dana DevineGammon RR, Devine D, Katz LM, Quinley E, Wu Y, Rowe K, Razatos A, Min K, Reichenberg S, Smith R. Buffy coat platelets coming to America: Are we ready? Transfusion. 2021 Feb;61(2):627-633. doi: 10.1111/trf.16184. Epub 2020 Nov 10. PMID: 33174258.1. journals2021
Dana DevineHadjesfandiari N, Levin E, Serrano K, Yi QL, Devine DV. Risk analysis of transfusion of cryoprecipitate without consideration of ABO group. Transfusion. 2021 Jan;61(1):29-34. doi: 10.1111/trf.16125. Epub 2020 Oct 10. PMID: 33037661.1. journals2021
Dana DevineBégin P, Callum J, Jamula E, Cook R, Heddle NM, Tinmouth A, Zeller MP, Beaudoin-Bussières G, Amorim L, Bazin R, Loftsgard KC, Carl R, Chassé M, Cushing MM, Daneman N, Devine DV, Dumaresq J, Fergusson DA, Gabe C, Glesby MJ, Li N, Liu Y, McGeer A, Robitaille N, Sachais BS, Scales DC, Schwartz L, Shehata N, Turgeon AF, Wood H, Zarychanski R, Finzi A; CONCOR-1 Study Group, Arnold DM. Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial. Nat Med. 2021 Nov;27(11):2012-2024. doi: 10.1038/s41591-021-01488-2. Epub 2021 Sep 9. PMID: 34504336; PMCID: PMC8604729.1. journals2021
Dana DevinePeng HT, Rhind SG, Devine D, Jenkins C, Beckett A. Ex vivo hemostatic and immuno-inflammatory profiles of freeze-dried plasma. Transfusion. 2021 Jul;61 Suppl 1:S119-S130. doi: 10.1111/trf.16502. PMID: 34269465.1. journals2021
Dana DevineSchubert P, Chen Z, Bhakta V, Culibrk B, Wambolt R, Sheffield WP, Devine DV, McTaggart K. Cold-stored leukoreduced whole blood: Extending the time between donation and filtration has minimal impact on in vitro quality. Transfusion. 2021 Jul;61 Suppl 1:S131-S143. doi: 10.1111/trf.16540. PMID: 34269454.1. journals2021
Dana DevineCardigan R, New HV, Estcourt L, Zhiburt E, Dubey R, Bengtsson J, Jöud M, Castillo C, Cid J, Lozano M, Gounder D, Flanagan P, Morley S, Clarke G, Devine D, Hindawi S, AlOtaibi A, Bub CB, Kutner JM, Ikeda T, Goto N, Okazaki H, Fontaine MJ, Pasion J, Song L, Latham T, Kerkhoffs JL, de Haas M, Zwaginga JJ, Gathof BS, Ommer K, Pirenne F, Raba M, Francois A, Daly J, Powley T, Dunbar N. International Forum on Policies and Practice for Transfusion of ABO and RhD Non-Identical Platelets: Summary. Vox Sang. 2021 Jul 14. doi: 10.1111/vox.13129. Epub ahead of print. PMID: 34258783.1. journals2021
Dana DevineCardigan R, New HV, Estcourt L, Zhiburt E, Dubey R, Bengtsson J, Jöud M, Castillo C, Cid J, Lozano M, Gounder D, Flanagan P, Morley S, Clarke G, Devine D, Hindawi S, AlOtaibi A, Bub CB, Kutner JM, Ikeda T, Goto N, Okazaki H, Fontaine MJ, Pasion J, Song L, Latham T, Kerkhoffs JL, de Haas M, Zwaginga JJ, Gathof BS, Ommer K, Pirenne F, Raba M, Francois A, Daly J, Powley T, Dunbar N. International Forum on Policies and Practice for Transfusion of ABO and RhD Non-Identical Platelets: Responses. Vox Sang. 2021 Jul 14. doi: 10.1111/vox.13130. Epub ahead of print. PMID: 34258774.1. journals2021
Dana DevineSchubert P, Johnson L, Culibrk B, Chen Z, Tan S, Marks DC, Devine DV. Reconstituted cryopreserved platelets synthesize proteins during short-term storage and packaging a defined subset into microvesicles. Transfusion. 2021 Sep;61(9):2549-2555. doi: 10.1111/trf.16542. Epub 2021 Jun 14. PMID: 34121199.1. journals2021
Dana DevineAl-Riyami AZ, Burnouf T, Yazer M, Triulzi D, Kumaş LT, Sağdur L, Pelit NB, Bazin R, Hindawi SI, Badawi MA, Patidar GK, Pandey HC, Chaurasia R, Fachini RM, Scuracchio P, Wendel S, Ang AL, Ong KH, Young P, Ihalainen J, Vierikko A, Qiu Y, Yang R, Xu H, Rahimi-Levene N, Shinar E, Izak M, Gonzalez CA, Ferrari DM, Cini PV, Aditya RN, Sharma RR, Sachdev S, Hans R, Lamba DS, Nissen-Meyer LSH, Devine DV, Lee CK, Leung JN, Hung IFN, Tiberghien P, Gallian P, Morel P, Al Maamari K, Al-Hinai Z, Vrielink H, So-Osman C, De Angelis V, Berti P, Ostuni A, Marano G, Nevessignsky MT, El Ekiaby M, Daly J, Hoad V, Kim S, van den Berg K, Vermeulen M, Glatt TN, Schäfer R, Reik R, Gammon R, Lopez M, Estcourt L, MacLennan S, Roberts D, Louw V, Dunbar N; ISBT Convalescent Plasma Group. International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Protocols, Challenges and Lessons Learned: Summary. Vox Sang. 2021 May 20:10.1111/vox.13113. doi: 10.1111/vox.13113. Epub ahead of print. PMID: 34013968; PMCID: PMC8242386.1. journals2021
Dana DevineDevine DV. Rethinking platelet transfusion practices. Blood. 2021 May 13;137(19):2576-2577. doi: 10.1182/blood.2021011269. PMID: 33983425.1. journals2021
Dana DevineVardaki MZ, Schulze HG, Serrano K, Blades MW, Devine DV, Turner RFB. Non-invasive monitoring of red blood cells during cold storage using handheld Raman spectroscopy. Transfusion. 2021 Jul;61(7):2159-2168. doi: 10.1111/trf.16417. Epub 2021 May 10. PMID: 33969894.1. journals2021
Dana DevineBégin P, Callum J, Heddle NM, Cook R, Zeller MP, Tinmouth A, Fergusson DA, Cushing MM, Glesby MJ, Chassé M, Devine DV, Robitalle N, Bazin R, Shehata N, Finzi A, McGeer A, Scales DC, Schwartz L, Turgeon AF, Zarychanski R, Daneman N, Carl R, Amorim L, Gabe C, Ellis M, Sachais BS, Loftsgard KC, Jamula E, Carruthers J, Duncan J, Lucier K, Li N, Liu Y, Armali C, Kron A, Modi D, Auclair MC, Cerro S, Avram M, Arnold DM. Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): study protocol for an international, multicentre, randomized, open-label trial. Trials. 2021 May 4;22(1):323. doi: 10.1186/s13063-021-05235-3. PMID: 33947446; PMCID: PMC8094980.1. journals2021
Dana DevineMartinaud C, Scorer T, Lozano M, Miles A, Fitchett G, Ba A, Wikman A, Nimberger-Hansson P, Enbuske S, Bohonek M, Devine D, Beckett AN, Mbanya D, T'Sas F, Degueldre J, Chueca M, Dedome E, Apelseth T, Strandenes G, Wendel S, Fachini R, Olszewski A, Dupont C, Glassberg E, Shinar E, Taylor AL, Corley JB, Sekaran Nadarajan V, Dunbar N. International Forum on Walking Blood Bank Programmes: Summary. Vox Sang. 2021 Sep;116(8):924-929. doi: 10.1111/vox.13101. Epub 2021 May 3. PMID: 33939181.1. journals2021
Dana DevineMartinaud C, Scorer T, Lozano M, Miles A, Fitchett G, Ba A, Wikman A, Nimberger-Hansson P, Enbuske S, Bohonek M, Devine D, Beckett AN, Mbanya D, T'Sas F, Degueldre J, Chueca M, Dedome E, Apelseth T, Strandenes G, Wendel S, Fachini R, Olszewski A, Dupont C, Glassberg E, Shinar E, Taylor AL, Corley JB, Nadarajan VS, Dunbar N. International Forum on Walking Blood Bank Programmes: Responses. Vox Sang. 2021 Sep;116(8):e44-e70. doi: 10.1111/vox.13102. Epub 2021 May 3. PMID: 33939177.1. journals2021
Dana DevineHadjesfandiari N, Khorshidfar M, Devine DV. Current Understanding of the Relationship between Blood Donor Variability and Blood Component Quality. Int J Mol Sci. 2021 Apr 11;22(8):3943. doi: 10.3390/ijms22083943. PMID: 33920459; PMCID: PMC8069744.1. journals2021
Dana DevineZhao HW, Serrano K, Stefanoni D, D'Alessandro A, Devine DV. In Vitro Characterization and Metabolomic Analysis of Cold-Stored Platelets. J Proteome Res. 2021 May 7;20(5):2251-2265. doi: 10.1021/acs.jproteome.0c00792. Epub 2021 Mar 29. PMID: 33780259.1. journals2021
Dana DevineWendel S, Land K, Devine DV, Daly J, Bazin R, Tiberghien P, Lee CK, Arora S, Patidar GK, Khillan K, Smid WM, Vrielink H, Oreh A, Al-Riyami AZ, Hindawi S, Vermeulen M, Louw V, Burnouf T, Bloch EM, Goel R, Townsend M, So-Osman C. Lessons learned in the collection of convalescent plasma during the COVID-19 pandemic. Vox Sang. 2021 Sep;116(8):872-879. doi: 10.1111/vox.13096. Epub 2021 Mar 27. PMID: 33772791; PMCID: PMC8250874.1. journals2021
Dana DevineSchubert P, Culibrk L, Culibrk B, Conway EM, Goodrich RP, Devine DV. Releasates of riboflavin/UV-treated platelets: Microvesicles suppress cytokine-mediated endothelial cell migration/proliferation. Transfusion. 2021 May;61(5):1551-1561. doi: 10.1111/trf.16337. Epub 2021 Feb 24. PMID: 33629371.1. journals2021
Dana DevineCohn CS, Estcourt L, Grossman BJ, Pagano MB, Allen ES, Bloch EM, Casadevall A, Devine DV, Dunbar NM, Foroutan F, Gniadek TJ, Goel R, Gorlin J, Joyner MJ, Metcalf RA, Raval JS, Rice TW, Shaz BH, Vassallo RR, Winters JL, Beaudoin G, Tobian AAR. COVID-19 convalescent plasma: Interim recommendations from the AABB. Transfusion. 2021 Apr;61(4):1313-1323. doi: 10.1111/trf.16328. Epub 2021 Mar 7. PMID: 33586160; PMCID: PMC8014606.1. journals2021
Daniel HolmesGrober ED, Krakowsky Y, Khera M, Holmes DT, Lee JC, Grantmyre JE, Patel P, Bebb RA., Fitzpatrick R, Campbell JD, Carrier S, & Morgentaler A (2021). Canadian Urological Association guideline on testosterone deficiency in men: Evidence-based Q&A. Canadian Urological Association Journal, 15(5), E234€“E243. https://doi.org/10.5489/cuaj.72521. journals2021
Daniel HolmesKline GA, Symonds C J, & Holmes DT (2021). Intranasal corticosteroids may have systemic absorption and potential impact upon cortisol measures.1. journals2021
Daniel HolmesHolmes DT, Mobini M, & McCudden CR (2021). Reproducible manuscript preparation with RMarkdown application to JMSACL and other Elsevier Journals. Journal of Mass Spectrometry and Advances in the Clinical Lab, 22, 8€“16. https://doi.org/10.1016/j.jmsacl.2021.09.0021. journals2021
David FarnellChahal D, Hussaini T, Farnell D, Nador R, Yoshida EM. Isolated Liver Rejection After Lung and Combined Kidney-Liver Transplantation: A Case Report. Transplant Proc. 2021 Mar 6:S0041-1345(21)00113-5. doi: 10.1016/j.transproceed.2021.02.004. Epub ahead of print. PMID: 33750588.1. journals2021
David GoldfarbGoldfarb DM, Tilley P, Al-Rawahi GN, Srigley JA, Ford G, Pedersen H, Pabbi A, Hannam-Clark S, Charles M, Dittrick M, Gadkar VJ, Pernica JM, Hoang LMN. Self-Collected Saline Gargle Samples as an Alternative to Health Care Worker-Collected Nasopharyngeal Swabs for COVID-19 Diagnosis in Outpatients. J Clin Microbiol. 2021 Mar 19;59(4):e02427-20.1. journals2021
David Goldfarb Majdoubi A, Michalski C, O'Connell SE, Dada S, Narpala S, Gelinas J, Mehta D, Cheung C, Winkler DF, Basappa M, Liu AC, Görges M, Barakauskas VE, Irvine M, Mehalko J, Esposito D, Sekirov I, Jassem AN, Goldfarb DM, Pelech S, Douek DC, McDermott AB, Lavoie PM. A majority of uninfected adults show preexisting antibody reactivity against SARS-CoV-2. JCI Insight. 2021 Apr 22;6(8):e146316.1. journals2021
David GoldfarbEckbo EJ, Mijovic H, Tam J, Goldfarb DM, Kollmann TR. An unusual case of abdominal pain and splenomegaly in a paediatric patient. SAGE Open Med Case Rep. 2021 Feb 1;9:2050313X21991059.1. journals2021
David GoldfarbGadkar VJ, Goldfarb DM, Young V, Watson N, Al-Rawahi GN, Srigley JA, Tilley P. Development and validation of a new triplex real-time quantitative reverse Transcriptase-PCR assay for the clinical detection of SARS-CoV-2. Mol Cell Probes. 2021 Aug;58:101744.1. journals2021
David GoldfarbKinshella MW, Nyondo-Mipando AL, Dube Q, Goldfarb DM, Kawaza K. Facility assessment and qualitative analysis of health worker perspectives on neonatal health in Malawi. BMC Res Notes. 2021 Jul 12;14(1):267.1. journals2021
David GoldfarbCollins SA, Edmunds S, Akearok GH, Thompson JR, Erickson AC, Hildes-Ripstein E, Miners A, Somerville M, Goldfarb DM, Rockman-Greenberg C, Arbour L. Association of the CPT1A p.P479L Metabolic Gene Variant With Childhood Respiratory and Other Infectious Illness in Nunavut. Front Pediatr. 2021 Jul 6;9:678553.1. journals2021
David GoldfarbNyondo-Mipando AL, Kinshella MW, Hiwa T, Salimu S, Banda M, Vidler M, Molyneux E, Dube Q, Goldfarb DM, Kawaza K. Mothers' quality of life delivering kangaroo mother care at Malawian hospitals: a qualitative study. Health Qual Life Outcomes. 2021 Jul 28;19(1):186.1. journals2021
David GoldfarbFinlayson-Trick E, Barker B, Manji S, Harper SL, Yansouni CP, Goldfarb DM. Climate Change and Enteric Infections in the Canadian Arctic: Do We Know What€™s on the Horizon? Gastrointestinal Disorders. 2021; 3(3):113-126.1. journals2021
David GoldfarbPernica JM, Smaill F, Kam AJ, Bartholomew A, Doan Q, Smieja M, Khan S, Sung M, Thabane L, Goldfarb DM. Single-centre, open-label, randomised, trial to compare rapid molecular point-of-care streptococcal testing to standard laboratory-based testing for the management of streptococcal pharyngitis in children: study protocol. BMJ Open. 2021 Aug 11;11(8):e047271.1. journals2021
David GoldfarbSekirov I, Barakauskas VE, Simons J, Cook D, Bates B, Burns L, Masud S, Charles M, McLennan M, Mak A, Chahil N, Vijh R, Hayden A, Goldfarb D, Levett PN, Krajden M, Morshed M. SARS-CoV-2 serology: Validation of high-throughput chemiluminescent immunoassay (CLIA) platforms and a field study in British Columbia. J Clin Virol. 2021 Sep;142:104914.1. journals2021
David GoldfarbNyondo-Mipando AL, Kinshella MW, Salimu S, Chiwaya B, Chikoti F, Chirambo L, Mwaungulu E, Banda M, Newberry L, Hiwa T, Vidler M, Dube Q, Molyneux E, Mfutso-Bengo J, Goldfarb DM, Kawaza K. Familiar but neglected: identification of gaps and recommendations to close them on exclusive breastfeeding support in health facilities in Malawi. Int Breastfeed J. 2021 Sep 26;16(1):72.1. journals2021
David GoldfarbHung TY, Coates E, McAlpine A, Tam J, Goldfarb DM, McDonald PJ, Zelman M, Halverson M, Seaton C. Cephalohaematoma: Not always a benign bump. J Paediatr Child Health. 2021 Oct 21. doi: 10.1111/jpc.15769. Epub ahead of print.1. journals2021
David GoldfarbKinshella MW, Tilley P, Al-Rawahi GN, Srigley JA, Kayda I, Canes M, McLennan M, Bone JN, Dittrick M, Gadkar VJ, Hoang LMN, Goldfarb DM. Evaluation of observed and unobserved self-collection of saline gargle samples for the detection of SARS-CoV-2 in outpatients. Diagn Microbiol Infect Dis. 2021 Oct 2;102(2):115566. doi: 10.1016/j.diagmicrobio.2021.115566. Epub ahead of print.1. journals2021
David GoldfarbGrunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O'Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM. A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval. Clin Infect Dis. 2021 Nov 30:ciab938. doi: 10.1093/cid/ciab938. Epub ahead of print.1. journals2021
David GoldfarbCholette F, Mesa C, Harris A, Ellis H, Cachero K, Lacap P, Galipeau Y, Langlois MA, Gingras AC, Yansouni CP, Papenburg J, Cheng MP, Chakraborty P, Stein DR, Van Caeseele P, Bartlett S, Krajden M, Goldfarb D, McGeer A, Osiowy C, Hankins C, Mazer B, Drebot M, Kim J; COVID-19 Immunity Task Force (CITF) working group. Dried blood spot specimens for SARS-CoV-2 antibody testing: A multi-site, multi-assay comparison. PLoS One. 2021 Dec 7;16(12):e0261003.1. journals2021
David GoldfarbGrunau B, Goldfarb DM, Asamoah-Boaheng M, Golding L, Kirkham TL, Demers PA, Lavoie PM. Immunogenicity of Extended mRNA SARS-CoV-2 Vaccine Dosing Intervals. JAMA. 2021 Dec 3:e2121921. doi: 10.1001/jama.2021.21921. Epub ahead of print.1. journals2021
David GranvilleTurner CT, Zeglinski MR, Richardson KC, Santacruz S, Hiroyasu S, Wang C, Zhao H, Shen Y, Sehmi R, Lima H, Gauvreau GM, Granville DJ. Granzyme B contributes to barrier dysfunction in oxazolone-induced skin inflammation through E-cadherin and FLG cleavage. J. Invest. Dermatol. 2021: 141(1):36-47. SA1. journals2021
David GranvilleHiroyasu S, Zeglinski MR, Zhao H, Pawluk MA, Turner CT, Kasprick A, Tateishi C, Nishie W, Burleigh A, Lennox PA, Van Laeken N, Carr NJ, Peterson F, Crawford RI, Shimizu H, Tsuruta D, Ludwig RJ, Granville DJ. Granzyme B Inhibition Reduces Disease Severity in Autoimmune Blistering Diseases. Nature Comm. 2021 12(1):302. doi: 10.1038/s41467-020-20604-3. SA (IF 14.9)1. journals2021
David GranvilleGapud EJ, Trejo-Zambrano MI, Gomez-Banuelos E, Tiniakou E, Antiochos B, Granville DJ, Andrade, Casciola-Rosen L, Rosen A. Granzyme B induces IRF-3 phosphorylation through a perforin-independent proteolysis-dependent signaling cascade without inducing cell death. J. Immunol. 2021 206(2):335-344. doi: 10.4049/jimmunol.2000546. . CA (IF 5.4)1. journals2021
David GranvilleTurner CT, Bolsoni J, Zeglinski MR, Zhao, H, Ponomarev T, Richardson K, Hiroyasu S, Schmid E, Papp A, Granville DJ. Granzyme B Mediates Impaired Healing of Pressure Injuries in Aged Skin. NPJ Aging Mech Dis. 2021 7(1):6. doi: 10.1038/s41514-021-00059-6.1. journals2021
David GranvilleHu MD, Golovchenko NB, Kelly TJ, Agos J, Zeglinski M, Turner JR, Bonder EM, Granville DJ, Watson AJM, Edelblum KL.  intraepithelial lymphocytes facilitate pathological intestinal epithelial cell shedding through CD103-mediated granzyme release. Gastroenterology. 2021 Dec 1:S0016-5085(21)03804-X. doi: 10.1053/j.gastro.2021.11.028. CA (IF 22.68)1. journals2021
David GranvilleHayes B, Fossey M, Poormasjedi-Meibod M, Erskine E, Soriano JE, Scott B, Rosentreter R, Granville DJ, Phillips A, West C. Experimental high thoracic spinal cord injury impairs the cardiac and cerebrovascular response to orthostatic challenge in rats. Am. J. Physiol. Heart Circ. Physiol. Am J Physiol Heart Circ Physiol. 2021 Oct 1;321(4):H716-H727. doi: 10.1152/ajpheart.00239.2021. CA (IF 3.8)1. journals2021
David GranvilleHiroyasu S, Hiroyasu A, Granville DJ, Tsuruta D. Pathological functions of granzyme B in inflammatory skin diseases. J Dermatol Sci. 2021 104(2):76-82. doi: 10.1016/j.jdermsci.2021.10.006. 1. journals2021
David GrynspanWhite M, Grynspan D, Van Mieghem T, Connor KL. Isolated fetal neural tube defects associate with increased risk of placental pathology: Evidence from the Collaborative Perinatal Project. Placenta. 2021 Oct;114:56-67. doi: 10.1016/j.placenta.2021.08.052. Epub 2021 Aug 18. PMID: 34479062.1. journals2021
David HuntsmanCunningham JM, Winham SJ, Wang C, Weigelt B, Fu Z, Armasu SM, McCauley BM, Brand AH, Chiew YE, Elishaev E, Gourley C, Kennedy CJ, Laslvic A, Lester J, Piskorz A, Sekowska M, Brenton JD, Churchman M, DeFazio A, Drapkin R, Elias KM, Huntsman DG, Karlan BY, Köbel M, Konner J, Lawrenson K, Papaemmanuil E, Bolton KL, Modugno F, Goode EL. DNA Methylation Profiles of Ovarian Clear Cell Carcinoma. Cancer Epidemiol Biomarkers Prev. 2021 Oct 25:cebp.0677.2021. doi: 10.1158/1055-9965.EPI-21-0677. Epub ahead of print.1. journals2021
David HuntsmanPilsworth JA, Cochrane DR, Neilson SJ, Moussavi BH, Lai D, Munzur AD, Senz J, Wang YK, Zareian S, Bashashati A, Wong A, Keul J, Staebler A, van Meurs HS, Horlings HM, Kommoss S, Kommoss F, Oliva E, Färkkilä AE, Gilks B, Huntsman DG. Adult-type granulosa cell tumor of the ovary: a FOXL2-centric disease. J Pathol Clin Res. 2021 Jan 11. doi: 10.1002/cjp2.198. Epub ahead of print. PMID: 33428330.1. journals2021
David HuntsmanBoschman J, Farahani H, Darbandsari A, Ahmadvand P, Van Spankeren A, Farnell D, Levine AB, Naso JR, Churg A, Jones SJ, Yip S, Köbel M, Huntsman DG, Gilks CB, Bashashati A. The utility of color normalization for AI-based diagnosis of hematoxylin and eosin-stained pathology images. J Pathol. 2021 Sep 20. doi: 10.1002/path.5797. Epub ahead of print.1. journals2021
David HuntsmanNaso JR, Tessier-Cloutier B, Senz J, Huntsman DG, Churg A. Significance of p53 immunostaining in mesothelial proliferations and correlation with TP53 mutation status. Mod Pathol. 2021 Sep 8. doi: 10.1038/s41379-021-00920-9. Epub ahead of print.1. journals2021
David HuntsmanQuinn MCJ, McCue K, Shi W, Johnatty SE, Beesley J, Civitarese A, O'Mara TA, Glubb DM, Tyrer JP, Armasu SM, Ong JS, Gharahkhani P, Lu Y, Gao B, Patch AM, Fasching PA, Beckmann MW, Lambrechts D, Vergote I, Velez Edwards DR, Beeghly-Fadiel A, Benitez J, Garcia MJ, Goodman MT, Dörk T, Dürst M, Modugno F, Moysich K, du Bois A, Pfisterer J, Bauman K, Karlan BY, Lester J, Cunningham JM, Larson MC, McCauley BM, Kjaer SK, Jensen A, Hogdall CK, Hogdall E, Schildkraut JM, Riggan MJ, Berchuck A, Cramer DW, Terry KL, Bjorge L, Webb PM, Friedlander M, Pejovic T, Moffitt M, Glasspool R, May T, Ene GEV, Huntsman DG, Woo M, Carney ME, Hinsley S, Heitz F, Fereday S, Kennedy CJ, Edwards SL, Winham SJ, deFazio A, Pharoah PDP, Goode EL, MacGregor S, Chenevix-Trench G; AGO Study Group; OPAL Study Group; for Australian Ovarian Cancer Study Group. Identification of a Locus Near ULK1 Associated With Progression-Free Survival in Ovarian Cancer. Cancer Epidemiol Biomarkers Prev. 2021 Sep; 30 (9):1669-1680. doi: 10.1158/1055-9965.EPI-20-1817.1. journals2021
David HuntsmanPilsworth JA, Todeschini AL, Neilson SJ, Cochrane DR, Lai D, Anttonen M, Heikinheimo M, Huntsman DG, Veitia RA. FOXL2 in adult-type granulosa cell tumour of the ovary: oncogene or tumour suppressor gene? J Pathol. 2021 Aug 2. doi: 10.1002/path.57711. journals2021
David HuntsmanTeng K, Ford MJ, Harwalkar K, Li Y, Pacis AS, Farnell D, Yamanaka N, Wang YC, Badescu D, Ton Nu TN, Ragoussis J, Huntsman DG, Arseneau J, Yamanaka Y. Modeling High-grade serous ovarian carcinoma using a combination of in vivo fallopian tube electroporation and CRISPR-Cas9-mediated genome editing. Cancer Res. 2021 Jul 23:canres.1518.2020. doi: 10.1158/0008-5472.CAN-20-1518. Epub ahead of print.1. journals2021
David HuntsmanHuvila J, Cochrane DR, Ta M, Chow C, Greening K, Leung S, Karnezis AN, DiFeo A, Huntsman DG. STING pathway expression in low-grade serous carcinoma of the ovary: an unexpected therapeutic opportunity? J Pathol Clin Res. 2021 Nov; 7(6): 548€“555.1. journals2021
David HuntsmanWu S, Fukumoto T, Lin J, Nacarelli T, Wang Y, Ong D, Liu H, Fatkhutdinov N, Zundell JA, Karakashev S, Zhou W, Schwartz LE, Tang HY, Drapkin R, Liu Q, Huntsman DG, Kossenkov AV, Speicher DW, Schug ZT, Van Dang C, Zhang R. Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma. Nat Cancer. 2021 Feb;2(2):189-200. doi: 10.1038/s43018-020-00160-x1. journals2021
David HuntsmanTsai S, Fournier LA, Chang EY, Wells JP, Minaker SW, Zhu YD, Wang AY, Wang Y, Huntsman DG, Stirling PC. ARID1A regulates R-loop associated DNA replication stress. PLoS Genet. 2021 Apr 7;17(4):e1009238. doi: 10.1371/journal.pgen.1009238.1. journals2021
David HuntsmanDixon K, Brew T, Farnell D, Godwin TD, Cheung S, Chow C, Ta M, Ho G, Bui M, Douglas JM, Campbell KR, El-Naggar A, Kaurah P, Kalloger SE, Lim HJ, Schaeffer DF, Cochrane D, Guilford P, Huntsman DG. Modelling hereditary diffuse gastric cancer initiation using transgenic mouse-derived gastric organoids and single-cell sequencing. J Pathol. 2021 Jul; 254(3):254-264.1. journals2021
David HuntsmanAsiimwe R, Lam S, Leung S, Wang S, Wan R, Tinker A, McAlpine JN, Woo MMM, Huntsman DG, Talhouk A. From biobank and data silos into a data commons: convergence to support translational medicine. J Transl Med. 2021 Dec 4;19(1):493. doi: 10.1186/s12967-021-03147-z.1. journals2021
David HuntsmanHeinze K, Nazeran TM, Lee S, Krämer P, Cairns ES, Chiu DS, Leung SCY, Kang EY, Meagher NS, Kennedy CJ, Boros J, Kommoss F, Vollert HW, Heitze F, du Bois A, Harter P, Grube M, Kraemer B, Staebler A, Kommoss FKF, Heublein S, Sinn HP, Singh N, Laslavic A, Elishaev E, Olawaiye A, Moysich K, Modugno F, Sharma R, Brand AH, Harnett PR, DeFazio A, Fortner RT, Lubinski J, Lener M, Tołoczko-Grabarek A, Cybulski C, Gronwald H, Gronwald J, Coulson P, El-Bahrawy MA, Jones ME, Schoemaker MJ, Swerdlow AJ, Gorringe KL, Campbell I, Cook L, Gayther SA, Carney ME, Shvetsov YB, Hernandez BY, Wilkens LR, Goodman MT, Mateoiu C, Linder A, Sundfeldt K, Kelemen LE, Gentry-Maharaj A, Widschwendter M, Menon U, Bolton KL, Alsop J, Shah M, Jimenez-Linan M, Pharoah PDP, Brenton JD, Cushing-Haugen KL, Harris HR, Doherty JA, Gilks B, Ghatage P, Huntsman DG, Nelson GS, Tinker AV, Lee CH, Goode EL, Nelson BH, Ramus SJ, Kommoss S, Talhouk A, Köbel M, Anglesio MS. Validated biomarker assays confirm ARID1A loss is confounded with MMR deficiency, CD8 TIL infiltration, and provides no independent prognostic value in endometriosis-associated ovarian carcinomas. J Pathol. 2021 Dec 13. doi: 10.1002/path.5849. Epub ahead of print1. journals2021
David HuntsmanMcAlpine JN, Chiu DS, Nout RA, Church DN, Schmidt P, Lam S, Leung S, Bellone S, Wong A, Brucker SY, Lee CH, Clarke BA, Huntsman DG, Bernardini MQ, Ngeow J, Santin AD, Goodfellow P, Levine DA, Köbel M, Kommoss S, Bosse T, Gilks CB, Talhouk A. Evaluation of treatment effects in patients with endometrial cancer and POLE mutations: An individual patient data meta-analysis. Cancer. 2021 Jul 15; 127 (14):2409-2422. doi: 10.1002/cncr.33516.1. journals2021
David HuntsmanHoppe MM, Jaynes P, Wardyn JD, Upadhyayula SS, Tan TZ, Lie S, Lim DGZ, Pang BNK, Lim S, P S Yeong J, Karnezis A, Chiu DS, Leung S, Huntsman DG, Sedukhina AS, Sato K, Topp MD, Scott CL, Choi H, Patel NR, Brown R, Kaye SB, Pitt JJ, Tan DSP, Jeyasekharan AD. Quantitative imaging of RAD51 expression as a marker of platinum resistance in ovarian cancer. EMBO Mol Med. 2021 May 7;13 (5):e13366. doi: 10.15252/emmm.202013366.1. journals2021
David HuntsmanHanker LC, El-Balat A, Drosos Z, Kommoss S, Karn T, Holtrich U, Gitas G, Graeser-Mayer M, Anglesio M, Huntsman D, Rody A, Gevensleben H, Hoellen F. Sphingosine-kinase-1 expression is associated with improved overall survival in high-grade serous ovarian cancer. J Cancer Res Clin Oncol. 2021 May;147 (5):1421-1430.1. journals2021
David HuntsmanGibbard E, Cochrane DR, Pors J, Negri GL, Colborne S, Cheng AS, Chow C, Farnell D, Tessier-Cloutier B, McAlpine JN, Morin GB, Schmidt D, Kommoss S, Kommoss F, Keul J, Gilks B, Huntsman DG, Hoang L. Whole-proteome analysis of mesonephric-derived cancers describes new potential biomarkers. Hum Pathol. 2021 Feb; 108:1-11.1. journals2021
David HuntsmanTessier-Cloutier B, Pors J, Thompson E, Ho J, Prentice L, McConechy M, Aguirre-Hernandez R, Miller R, Leung S, Proctor L, McAlpine JN, Huntsman DG, Gilks CB, Hoang LN. Molecular characterization of invasive and in situ squamous neoplasia of the vulva and implications for morphologic diagnosis and outcome. Mod Pathol. 2021 Feb;34 (2):508-518.1. journals2021
David HuntsmanKarnezis AN, Chen SY, Chow C, Yang W, Hendricks WPD, Ramos P, Briones N, Mes-Masson AM, Bosse T, Gilks CB, Trent JM, Weissman B, Huntsman DG, Wang Y. Re-assigning the histologic identities of COV434 and TOV-112D ovarian cancer cell lines. Gynecol Oncol. 2021 Feb;160 (2):568-5781. journals2021
David HuntsmanKarnezis AN, Chen SY, Chow C, Yang W, Hendricks WPD, Ramos P, Briones N, Mes-Masson AM, Bosse T, Gilks CB, Trent JM, Weissman B, Huntsman DG, Wang Y. Re-assigning the histologic identities of COV434 and TOV-112D ovarian cancer cell lines. Gynecol Oncol. 2021 Feb;160 (2):568-5781. journals2021
David HuntsmanKang EY, Cheasley D, LePage C, Wakefield MJ, da Cunha Torres M, Rowley S, Salazar C, Xing Z, Allan P, Bowtell DDL, Mes-Masson AM, Provencher DM, Rahimi K, Kelemen LE, Fasching PA, Doherty JA, Goodman MT, Goode EL, Deen S, Pharoah PDP, Brenton JD, Sieh W, Mateoiu C, Sundfeldt K, Cook LS, Le ND, Anglesio MS, Gilks CB, Huntsman DG, Kennedy CJ, Traficante N; Australian Ovarian Cancer Study, DeFazio A, Kaufmann S, Churchman M, Gourley C, Stephens AN, Meagher NS, Ramus SJ, Antill YC, Campbell I, Scott CL, Köbel M, Gorringe KL; GAMuT Collaborators. Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses. Mod Pathol. 2021 Jan;34(1):194-206.1. journals2021
David HuntsmanCheasley D, Nigam A, Zethoven M, Hunter S, Etemadmoghadam D, Semple T, Allan P, Carey MS, Fernandez ML, Dawson A, Köbel M, Huntsman DG, Le Page C, Mes-Masson AM, Provencher D, Hacker N, Gao Y, Bowtell D, deFazio A, Gorringe KL, Campbell IG. Genomic analysis of low-grade serous ovarian carcinoma to identify key drivers and therapeutic vulnerabilities. J Pathol. 2021 Jan; 253(1):41-54.1. journals2021
David SchaefferChu JE, Hamm J, Gentile L, Telford JJ, Schaeffer DF. Serrated Lesion Detection in a Population-based Colon Screening Program. J Clin Gastroenterol. 2021 Mar 12. SA1. journals2021
David SchaefferWeymann D, Pollard S, Chan B, Titmuss E, Bohm A, Laskin J, Jones SJM, Pleasance E, Nelson J, Fok A, Lim H, Karsan A, Renouf DJ, Schrader KA, Sun S, Yip S, Schaeffer DF, Marra MA, Regier DA. Clinical and cost outcomes following genomics-informed treatment for advanced cancers. Cancer Med. 2021 Jun 21. CA1. journals2021
David SchaefferMa C, Sedano R, Almradi A, Casteele NV, Parker CE, Guizzetti L, Schaeffer DF, Riddell RH, Pai RK, Battat R, Sands BE, Rosty C, Dubinsky MC, Rieder F, Harpaz N, Abreu MT, Bryant RV, Lauwers GY, Kirsch R, Valasek MA, Crowley E, Sandborn WJ, Feagan BG, Pai RK, Jairath V.  An international consensus to standardize integration of histopathology in ulcerative colitis clinical trials. Gastroenterology. 2021 Feb 18:S0016-5085(21)00423-6. CA1. journals2021
David SchaefferPai RK, Hartman D, Schaeffer DF, Rosty C, Shivji S, Kirsch R, Pai RK. Development and initial validation of a deep learning algorithm to quantify histologic features in colorectal carcinoma including tumour budding/poorly differentiated clusters. Histopathology. 2021 Feb 15. CA1. journals2021
David SchaefferAlmradi A, Ma C, D'Haens GR, Sandborn WJ, Parker CE, Guizzetti L, Borralho Nunes P, De Hertogh G, Feakins RM, Khanna R, Lauwers GY, Mookhoek A, Pai RK, Peyrin-Biroulet L, Riddell R, Rosty C, Schaeffer DF, Valasek MA, Singh S, Crowley E, Feagan BG, Jairath V, Pai RK. An expert consensus to standardise the assessment of histological disease activity in Crohn's disease clinical trials. Aliment Pharmacol Ther. 2021 Jan 7 CA1. journals2021
David SchaefferGolan T, O'Kane GM, Denroche RE, Raitses-Gurevich M, Grant RC, Holter S, Wang Y, Zhang A, Jang GH, Stossel C, Atias D, Halperin S, Berger R, Glick Y, Patrick Park JY, Cuggia A, Williamson L, Wong HL, Schaeffer DF, Renouf DJ, Borgida A, Dodd A, Wilson JM, Fischer SE, Notta F, Knox JJ, Zogopoulos G, Gallinger S. Genomic Features and Classification of Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma. Gastroenterology. 2021 Jan 29:S0016-5085(21)00326-7. CA1. journals2021
David SchaefferPai RK, Pai RK, Schaeffer DF, Choi WT, Kumarasinghe P, Brown I, Lauwers GY. Editorial: the microscope holds the key to predict need for biologic therapy in immunotherapy-checkpoint inhibitory colitis. Authors' reply. Aliment Pharmacol Ther. 2021 Mar;53(5):638-639. CA1. journals2021
David SchaefferSedano R, Ma C, Pai RK, D' Haens G, Guizzetti L, Shackelton LM, Remillard J, Gionchetti P, Gordon IO, Holubar S, Kayal M, Lauwers GY, Pai RK, Pardi DS, Samaan MA, Schaeffer DF, Shen B, Silverberg MS, Feagan BG, Sandborn WJ, Jairath V. An expert consensus to standardise clinical, endoscopic and histologic items and inclusion and outcome criteria for evaluation of pouchitis disease activity in clinical trials. Aliment Pharmacol Ther. 2021 Mar 18. CA1. journals2021
David SchaefferDixon K, Brew T, Farnell D, Godwin TD, Cheung S, Chow C, Ta M, Ho G, Bui M, Douglas JM, Campbell KR, El-Naggar A, Kaurah P, Kalloger SE, Lim HJ, Schaeffer DF, Cochrane D, Guilford P, Huntsman DG. Modelling hereditary diffuse gastric cancer initiation using transgenic mouse-derived gastric organoids and single-cell sequencing. J Pathol. 2021 Apr 2. CA1. journals2021
David SchaefferAlhussan A, Bromma K, Bozdoğan EPD, Metcalfe A, Karasinska J, Beckham W, Alexander AS, Renouf DJ, Schaeffer DF, Chithrani DB. Investigation of Nano-Bio Interactions within a Pancreatic Tumor Microenvironment for the Advancement of Nanomedicine in Cancer Treatment. Curr Oncol. 2021 May 24;28(3):1962-1979. CA1. journals2021
David SchaefferVerbeke C, Webster F, Brosens L, Campbell F, Del Chiaro M, Esposito I, Feakins RM, Fukushima N, Gill AJ, Kakar S, Kench JG, Krasinskas AM, van Laethem JL, Schaeffer DF, Washington K. Dataset for the reporting of carcinoma of the exocrine pancreas: recommendations from the International Collaboration on Cancer Reporting (ICCR). Histopathology. 2021 Aug 11. CA1. journals2021
David SchaefferMa C, Jairath V, Feagan BG, Guizzetti L, Zou G, McFarlane SC, Shackelton LM, Collins MH, Hirano I, de Rooij WE, Schaeffer DF, Pai RK, Bredenoord AJ, Dellon ES. Responsiveness of a Histologic Scoring System Compared With Peak Eosinophil Count in Eosinophilic Esophagitis. Am J Gastroenterol. 2021 Nov 19. CA1. journals2021
Davide SalinaTessier-Cloutier B, Twa DD, Marzban M, Kalina J, Chun HE, Pavey N, Tanweer Z, Katz RL, Lum JJ, Salina D. The presence of tumour-infiltrating neutrophils is an independent adverse prognostic feature in clear cell renal cell carcinoma. J Pathol Clin Res. 2021 Mar 4. doi: 10.1002/cjp2.204. Epub ahead of print. PMID: 33665979.1. journals2021
Davide SalinaDavid Saltman, Tyler Nielsen, Davide Salina, David Hout, Frank McMahon,  Boris Valev, Michael Huk, Pranil Chandra,  Jeremy Spille, Robert Seitz,  Brock Schweitzer. Characterization of the tumor immune-microenvironment of adenocarcinoma of lung with a metatstatic lesion in the pancreas treated successfully with first line, single agent pembrolizumab.  Therapeutic Advances in Medical Oncology, April 19 €™2021, Vol13.1. journals2021
Decheng YangZhao G, Aghakeshmiri S, Chen YT, Zhang HM, FYip F, Yang DC. NFAT5-Mediated Signalling Pathways in Viral Infection and Cardiovascular Dysfunction. Int. J. Mol. Sci. 2021, 22 (9): 4872.1. journals2021
Decheng YangZhang HM, Zhao G, Chen YT, Yip F, Yang DC. N6-methyladenosine modification promotes Coxsackievirus B3 replication through differential regulation of modification machinery and cleavage of reader protein YTHDF2. PLOS Pathogens. 2021 (in revision)1. journals2021
Decheng YangLei T, Zhang HM, Zhao G, Yang DC, Qiu Y. Genome-wide analysis of lncRNA expression and function in the infection of coxsackievirus B3. Frontiers in Microbiology 2021 (under review).1. journals2021
Decheng YangLi S, Armstrong N, Zhao H, Cruz-cosme  R, Yang H, Zhong C, Fu W, Wang W, Yang DC, Xia N, Cheng T, Tang Q. Zika Virus Infection Down Regulates Connexin 43, Disrupts the Cardiomyocyte Gap Junctions and Induces Heart Diseases in Adult A129 Mice. 2021, Journal of Infectious Diseases (in press).1. journals2021
Donald BrooksLi S, Huang Z, Li X, Zhao Y, Jiang X, Wen Y, Luo H, Wang L, Guan Q, Cafeeva I, Brooks DE, Nguan CYC, Kizhakkedathu JN, Du C. Evaluation of hyperbranched polyglycerol for cold perfusion and storage of donor kidneys in a pig model of kidney autotransplantation. J Biomed Mater Res B Appl Biomater. 2021 Jun;109(6):853-863. doi: 10.1002/jbm.b.34750. Epub 2020 Oct 24. PMID: 33098184; PMCID: PMC8246781.1. journals2021
Douglas MorrisonEric McGinnis; David Yang; Nicholas Au; Douglas Morrison; Kate M. Chipperfield; Audi F. Setiadi; Lorraine Liu; Angela Tsang; Suzanne M. Vercauteren. Clinical and laboratory features associated with myeloperoxidase expression in pediatric B-lymphoblasticleukemia. Cytometry. Part B, Clinical cytometry, 07/2021, Volume 100, Issue 4. DOI: 10.1093/ajcp/aqab0781. journals2021
Douglas MorrisonEric McGinnis; Robert J. Guo; Krista M. Marcon; Brian Berry; Robert Coupland; Victor Meneghetti; Douglas Morrison; Rodrigo Onell; Lisa Steele; Jacqueline Trudeau et al. Adaptations of transfusion systems to the COVID €19 pandemic in British Columbia, Canada : Early experiences of a large tertiary care center and survey of provincial activities. Transfusion. 2021;61:1102€“1111.  DOI: 10.1111/trf.162651. journals2021
Eric EckboEckbo EJ, Mijovic H, Tam J, Goldfarb DM, Kollmann TR. An unusual case of abdominal pain and splenomegaly in a paediatric patient. SAGE Open Med Case Rep. 2021 Feb 1;9:2050313X21991059. doi: 10.1177/2050313X21991059. PMID: 33796309; PMCID: PMC7970672.1. journals2021
Eric EckboEckbo EJ, Wong T, Bharat A, Cameron-Lane M, Hoang L, Dawar M, Charles M. First reported outbreak of the emerging pathogen Candida auris in Canada. Am J Infect Control. 2021 Jan 21:S0196-6553(21)00025-0. doi: 10.1016/j.ajic.2021.01.013. Epub ahead of print. PMID: 33485922.1. journals2021
Eric EckboEckbo EJ, Charles M, Wolber R, Yu G. Relapsing fever in a traveller returning from Senegal. CMAJ. 2021 Feb 22;193(8):E285-E288. doi: 10.1503/cmaj.201644. PMID: 33619068.1. journals2021
Eric McGinnisMartin SD, McGinnis E, Smith TW. Indicators Differentiating Thrombotic Thrombocytopenic Purpura From Other Thrombotic Microangiopathies in a Canadian Apheresis Referral Center. Am J Clin Pathol. 2021 Nov 8;156(6):1103-1112. doi: 10.1093/ajcp/aqab078. PMID: 34160013.1. journals2021
Eric McGinnisMcGinnis E, Yang D, Au N, Morrison D, Chipperfield KM, Setiadi AF, Liu L, Tsang A, Vercauteren SM. Clinical and laboratory features associated with myeloperoxidase expression in pediatric B-lymphoblastic leukemia. Cytometry B Clin Cytom. 2021 Jul;100(4):446-453. doi: 10.1002/cyto.b.21966. Epub 2020 Oct 13. PMID: 33048471.1. journals2021
Eric McGinnisMcGinnis E, Guo RJ, Marcon KM, Berry B, Coupland R, Meneghetti V, Morrison D, Onell R, Steele L, Trudeau J, Wong M, Shih AW. Adaptations of transfusion systems to the COVID-19 pandemic in British Columbia, Canada: Early experiences of a large tertiary care center and survey of provincial activities. Transfusion. 2021 Apr;61(4):1102-1111. doi: 10.1111/trf.16265. Epub 2021 Jan 16. PMID: 33452826; PMCID: PMC8014229.1. journals2021
Eric McGinnisMcGinnis E, Chan G, Hudoba M, Markin T, Yakimec J, Roland K. Malaria Screening Using Front-Line Loop-Mediated Isothermal Amplification. Am J Clin Pathol. 2021 Apr 26;155(5):690-697. doi: 10.1093/ajcp/aqaa173. PMID: 33283225.1. journals2021
Fumio TakeiGhaedi M & Takei F. Innate lymphoid cell development. J Allergy Clin Immunol 147:1549-1560, 2021.1. journals2021
Fumio TakeiMatha L, Martinez-Gonzalez I, Steer CA & Takei F. The Fate of Activated Group 2 Innate Lymphoid Cells. Front Immunol 12:671966, 2021.1. journals2021
Fumio TakeiMatha L, Romera-Hernandez M, Steer CA, Yin YH, Orangi M, Shim H, Chang C, Rossi FM & Takei F. Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity. Front Immunol 12:679509, 2021.1. journals2021
Fumio TakeiMatha L, Shim H, Steer CA, Yin YH, Martinez-Gonzalez I & Takei F. Correction: Female and male mouse lung group 2 innate lymphoid cells differ in gene expression profiles and cytokine production. PLoS One 16:e0252257, 2021. 1. journals2021
G R Wayne MooreHolmes RD, Vavasour IM, Greenfield J, Zhao G, Lee JS, Moore GRW, Tam R, Metz LM, Traboulsee A, Li DKB, Laule C. Nonlesional diffusely abnormal appearing white matter in clinically isolated syndrome: Prevalence, association with clinical and MRI features, and risk for conversion to multiple sclerosis. J Neuroimaging. First published: 15 June 2021 https://doi.org/10.1111/jon.12900.1. journals2021
G R Wayne MooreBlandford SN, Galloway DA, Williams JB, Arsenault S, Brown J, MacLean G, Moore GRW, Barron J, Ploughman M, Clift F, Stefanelli M, Moore C. Interleukin-1 receptor antagonist: An exploratory plasma biomarker that correlates with disability and provides pathophysiological insights in relapsing-remitting multiple sclerosis. Mult Scler and Rel Dis 52 (2021) 103006.1. journals2021
G R Wayne MoorePrevost, VH, Yung A, Morris SR, Vavasour IM, Samadi-Bahrami Z, Moore GRW, Laule C, MacKay A, Kozlowski P. Temperature dependence and histological correlation of inhomogeneous magnetization transfer and myelin water imaging in ex vivo brain. Neuroimage 236: 2021 Apr 10 118046/ j.neuroimage.2021. 118046, Online ahead of print.1. journals2021
G R Wayne MooreOntaneda D, Raza PC, Arnold DL, Dwyer MG, Gauthier SM, Greve DN, Harrison DM, Henry RG, Li DKB, Mahajan KR, Mainero C, Moore W, Narayanan S, Oh J, Patel R, Pelletier D, Rauscher A, Rooney WD, Sicotte NL, Tam R, Reich DS, and Azevedo CJ, on behalf of the North American Imaging in Multiple Sclerosis Cooperative (NAIMS) Deep gray matter injury: A North American Imaging in Multiple Sclerosis consensus statement. Brain 144 (7): 1974-1984, 20211. journals2021
Gang WangFan J, Yuan R, Stefanelli D, Wang G. Metastatic Seminoma with Positive Staining of Cytokeratin and MOC31: A Diagnostic Pitfall. Case Rep Pathol. 2021;2021:99929781. journals2021
Gang WangLavoie JM, Vandekerkhove G, Murtha AJ, Wang G, Wyatt AW, Eigl BJ. Development of secondary urothelial carcinoma following complete response to immune checkpoint inhibitors. Urol Case Rep. 2021;39:1017621. journals2021
Gang WangNaso,J.R., Banyi,N., Al-Hashami,Z., Zhu,J., Wang,G., Ionescu,D.N., Ho,C. Discordance in PD-L1 scores on repeat testing of non-small cell lung carcinomas. Cancer Treat Res Commun. 2021;27:1003531. journals2021
Gang WangNaso,J.R., Povshedna,T., Wang,G., Banyi,N., MacAulay,C., Ionescu,D.N., Zhou,C. Automated PD-L1 Scoring for Non-Small Cell Lung Carcinoma Using Open-Source Software. Pathology and Oncology Research. 2021;27:6097171. journals2021
Gang WangVandekerkhove,G., Lavoie,J.M., Annala,M., Murtha,A.J., Sundahl,N., Walz,S., Sano,T., Taavitsainen,S., Ritch,E., Fazli,L., Hurtado-Coll,A., Wang,G, Nykter,M., Black,P.C., Todenhöfer,T., Ost,P., Gibb,E.A., Chi,K.N., Eigl,B.J., Wyatt,A.W. Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer. Nature Communications. 2021;12(1):1841. journals2021
Gang WangZhang,X., Su,M.W., Cheng,Y., Martinka,M., Wang,G., Huang,Y., Li,L., Zhou,Y. Immunohistochemistry analysis reveals lysyl oxidase-like 3 as a novel prognostic marker for primary melanoma. Melanoma Research. 2021;31(2):173-1771. journals2021
Gang WangWang,G., Black,P.C., Goebell,P.J., Ji,L., Cordon-Cardo,C., Schmitz-Dräger,B., HawesD., Czerniak,B., Minner,S., Sauter,G., Waldman,F., Groshen,S., Cote,R.J., Dinney,C.P. Prognostic Markers in pT3 Bladder Cancer: A Study from the International Bladder Cancer Tissue Microarray Project. Urologic Oncology: Seminars and Original Investigations. 2021;39(5):301.e17-301.e281. journals2021
Gang WangNaso,J., Wang,G., Banyi,N., Shokoohi,A., Ho,C., Zhou,C., Ionescu,D.N. Comparability of Laboratory-Developed and Commercial PD-L1 Assays in Non-Small Cell Lung Carcinoma. Annals of Diagnostic Pathology. 2021;50:1515901. journals2021
Gang WangWarner,E.W, Herberts,C., Fu,S., YipS.M., Wong,A., Wang,G., Ritch,E., Murtha,A.J., Vandekerkhove,G., Fonseca,N., Angeles,A., Beigi,A., Schönlau,E., Beja,K., Annala,M., Khalaf,D.J., Chi,K.N., Wyatt,A.W. BRCA2, ATM, and CDK12 defects differentially shape prostate tumor driver genomics and clinical aggression. Clinical Cancer Research. 2021;27(6):1650-16621. journals2021
Gang WangWang G, Xiong W, Tucker T, Tran H, Nappi L, Yuan R. Primary pure carcinoid tumor of the testis: Radiology, pathology and molecular correlation. Urol Case Rep. 2021;39:1017871. journals2021
Gang WangWang G, Yuan R, Zhou C, Guo C, Villamil C, Hayes M, Eigl BJ, Black P. Urinary Large Cell Neuroendocrine Carcinoma: A Clinicopathologic Analysis of 22 Cases. Am J Surg Pathol. 2021;45(10):1399-14081. journals2021
Gerald KrystalElisia I, Krystal G. The pros and cons of low carbohydrate and ketogenic diets in the prevention and treatment of cancer. Front Nutr 25;8:634845, 2021.1. journals2021
Gerald KrystalCCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development. OncoImmunology. Accepted 2021.1. journals2021
Ghada Al RawahiAaron C. Liu, Melissa Harvey, Alison Lee, Kyla Hildebrand, Linda Hoang, Soren Gantt, and Ghada N. Al-Rawahi. Septic arthritis due to Mycoplasma orale in a young patient with hypogammaglobulinemia. Journal of the Association of Medical Microbiology and Infectious Diseases Canada (JAMMI). 2021 Dec 1; 6 (4):333-336. DOI: 10.3138/jammi-2021-0002
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1. journals2021
Ghada Al RawahiGadkar VJ, Goldfarb DM, Young V, Watson N, Al-Rawahi GN, Srigley JA, Tilley P. Development and validation of a new triplex real-time quantitative reverse Transcriptase-PCR assay for the clinical detection of SARS-CoV-2. Mol Cell Probes. 2021 Aug;58:101744. doi: 10.1016/j.mcp.2021.101744. Epub 2021 Jun 4. PMID: 34089805; PMCID: PMC8176879.1. journals2021
Ghada Al RawahiGoldfarb DM, Tilley P, Al-Rawahi GN, Srigley JA, Ford G, Pedersen H, Pabbi A, Hannam-Clark S, Charles M, Dittrick M, Gadkar VJ, Pernica JM, Hoang LMN. Self-Collected Saline Gargle Samples as an Alternative to Health Care Worker-Collected Nasopharyngeal Swabs for COVID-19 Diagnosis in Outpatients. J Clin Microbiol. 2021 Mar 19;59(4):e02427-20. doi: 10.1128/JCM.02427-20. PMID: 33514627; PMCID: PMC8092743.1. journals2021
Gill PavandeepCho WC, Gill P, Aung PP, Gu J, Nagarajan P, Ivan D, Curry JL, Prieto VG, Torres-Cabala CA. The utility of digital pathology in improving the diagnostic skills of pathology trainees in commonly encountered pigmented cutaneouslesions during the COVID-19 pandemic: a single academic institution experience. Annals of Diagnostic Pathology. 2021, 54: 151807.Link: https://doi.org/10.1016/j.anndiagpath.2021.1518071. journals2021
Gill PavandeepGill P, Richards K, Cho C, Nagarajan P, Aung P, Ivan D, Curry JL, Prieto VG, Torres-Cabala CA. Localized cutaneous argyria: Review of a rare clinical mimicker of melanocytic lesions. Annals of Diagnostic Pathology. 2021, 54: 151776.Link: https://doi.org/10.1016/j.anndiagpath.2021.151776
 
1. journals2021
Gill PavandeepGill P, Prieto VG, Austin MT, Torres Cabala C. Diagnostic utility of PRAME in distinguishing proliferative nodules from melanoma in giant congenital melanocytic nevi. Journal of Cutaneous Pathology, 2021 (Online ahead of print).Link: https://doi.org/10.1111/cup.140911. journals2021
Gill PavandeepGill P, Chia J, Street L, and Mahe E. Transformation of lymphomatoid papulosis type D to Berti€™s lymphoma. Histopathology. 2021, 79(3): 442-444.Link: https://doi.org/10.1111/his.144221. journals2021
Gill PavandeepGill P, Cho WC, Prieto VG, Nagarajan P. Metaplasia mimicking metastatic malignancy: a challenging case of florid eccrine squamous syringometaplasia. Journal of Cutaneous Pathology. 2021, 48(7): 995-998. Link: https://doi.org/10.1111/cup.140151. journals2021
Gill PavandeepJebain J, Siller A, Gill P, Prieto VG, Tyring SK. Recurrence of mucosal melanoma in Li-Fraumeni syndrome: a followup of an index case. JAAD Case Reports. 2021 April; 10: 31-33. Link: https://doi.org/10.1016/j.jdcr.2021.02.0081. journals2021
Gill PavandeepGill P and Aung P. Atypical fibroxanthoma. PathologyOutlines.com website. 16 March 2021. Link: https://www.pathologyoutlines.com/topic/skintumornonmelanocyticAFX.html.1. journals2021
Glenda HendsonZhang L, Delisle MF, Hendson G, Liauw J. Umbilical cord hemangioma with significant cord edema. J Obstet Gynaecol Can. 2021 Jul 22:S1701-2163(21)00579-X. doi: 10.1016/j.jogc.2021.06.012. 1. journals2021
Glenda HendsonChang CA, Perrier R, Kurek KC, Estrada-Veras J, Lehman A, Yip S, Hendson G, Diamond C, Pinchot JW, Tran JM, Arkin LM, Drolet BA, Napier MP, O'Neill SA, Balci TB, Keppler-Noreuil KM. Novel findings and expansion of phenotype in a mosaic RASopathy caused by somatic KRAS variants.Am J Med Genet A. 2021 Sep;185(9):2829-2845. doi: 10.1002/ajmg.a.62356. Epub 2021 May 30.PMID: 340568341. journals2021
Gordon RitchieA Stefanovic, N Reich, C Lowe, D Puddicombe, N Matic, J Greiner, J Simons, V Leung, T Chu, H Naik, N Myles, L Burns, M Romney, G Ritchie, S Champagne, K Dooley, I Sekirov, Repeat virological and serological profiles in hospitalized patients initially tested by nasopharyngeal RT-PCR for SARS-CoV-2, submitted to Journal of Medical Virology, accepted July 22, 2021 doi: 10.1002/jmv.272271. journals2021
Gordon RitchieNancy Matic, Christopher F Lowe, Gordon Ritchie, Aleksandra Stefanovic, Tanya Lawson, Willson Jang, Matthew Young, Winnie Dong, Zabrina L Brumme, Chanson J Brumme, Victor Leung, Marc G Romney, Rapid Detection of SARS-CoV-2 Variants of Concern, Including B.1.1.28/P.1, British Columbia, Canada Emerg Infect Dis, 2021 Jun, 27(6):1673-1676, Epub 2021 Mar 30, PMID: 33784237 PMCID: PMC8153894 DOI: 10.3201/eid2706.2105321. journals2021
Gordon RitchieR Cojocaru, I Yaseen, P Unrau, CF Lowe, G Ritchie, MG Romney, DD Sin, S Gill, M Slyandnev; Microchip RT-PCR Detection of Nasopharyngeal SARS-CoV-2 Samples. J Mol. Diagnostics (2021) March 08 https://doi.org/10.1016/j.jmoldx.2021.02.0091. journals2021
Gordon RitchieN Matic, A Stefanovic, V Leung, T Lawson, G Ritchie, L Li, S Champagne, MG Romne, DR Lowe ; Practical challenges to the Clinical Implementation of Saliva for SARS-CoV-2 detection. European J. Clin Micro Inf Dis (2021) 40:447-4501. journals2021
Gordon RitchieN Matic, T Lawson, G Ritchie, A Stefanovic, V Leung, S Champagne, MG Romney, CF Lowe; Automated Molecular Testing of Saliva for SARS-CoV-2 Detection. Diag Micro Inf Dis. (2021) 100(1-3) 1153241. journals2021
Gordon RitchieN Kinloch, G Ritchie, W Dong, K Cobarrubias, H Sudderuddin, T Lawson, N Matic, J Montaner, V Leung, M Romney, C Lowe, C Brumme,  Z Brumme; SARS-CoV-2 RNA quantification using droplet digital RT-PCR. Journal of Molecular Diagnostics. 2021 May 29;S1525-1578(21)00136-7. doi: 10.1016/j.jmoldx.2021.04.014. Online ahead of print.1. journals2021
Gordon RitchieNancy Matic, Christopher F Lowe, Gordon Ritchie, Aleksandra Stefanovic, Tanya Lawson, Willson Jang, Matthew Young, Winnie Dong, Zabrina L. Brumme, Chanson J Brumme, Victor Leung, Marc G Romney; Rapid detection of SARS-CoV-2 variants of concern identifying a cluster of B.1.1.28/P.1 variant in British Columbia, Canadadoi: https://doi.org/10.1101/2021.03.04.212529281. journals2021
Gordon RitchieS Chorlton, G Ritchie, T Lawson, E McLachlan, MG. Romney, N Matic, CF. Lowe; Next-generation sequencing for cytomegalovirus antiviral resistance genotyping in a clinical virology laboratory. Antiviral Research, accepted for publication June 22, 20211. journals2021
Gordon RitchieHarjot K. Bedi1, Roberto Trasolini1,2, Christopher F. Lowe3, Trana Hussaini4, Mark Bigham5, Gordon Ritchie3, Eric M. Yoshida*1,2, De Novo Hepatitis B Surface Antigen (HBsAg) Positive, Core Antibody (Anti-HBc) Negative, Hepatitis B Virus Infection post-Liver Transplant from an Anti-HBc, HBsAg Negative Donor, Accepted by: Hepatology Forum, Aug 13, 20211. journals2021
Graham SlackShopsowitz KE, Slack GW. B-lymphoblastic lymphoma presenting as a primary breast mass with periductal invasion. Blood. 2021 Dec 16;138(24):2593.1. journals2021
Graham SlackPatel N, Slack GW, Bodo J, Ben-Neriah S, Villa D, Durkin L, Socha D, Steidl C, Hsi ED.Immune Escape Mechanisms in Intravascular Large B-Cell Lymphoma. Am J Clin Pathol. 2021 Nov 11. journals2021
Graham SlackChen LYC, Slack GW, Carruthers MN. IgG4-related disease and Rosai-Dorfman-Destombes disease. Lancet. 2021 Oct 2;398(10307):1213-1214.1. journals2021
Graham SlackCheng PTM, Villa D, Tonseth RP, Scott DW, Gerrie AS, Freeman CL, Pickles T, Lo AC, Farinha P, Craig JW, Slack GW, Gascoyne RD, Bénard F, Wilson D, Skinnider B, Connors JM, Sehn LH, Savage KJ.Outcome of limited-stage nodular lymphocyte-predominant Hodgkin lymphoma and the impact of a PET-adapted approach. Blood Adv. 2021 Sep 28;5(18):3647-3655.1. journals2021
Graham SlackGould C, Lickiss J, Kankanige Y, Yerneni S, Lade S, Gandhi MK, Chin C, Yannakou CK, Villa D, Slack GW, Markham JF, Tam CS, Nelson N, Seymour JF, Dickinson M, Neeson PJ, Westerman D, Blombery P. Characterisation of immune checkpoints in Richter syndrome identifies LAG3 as a potential therapeutic target. Br J Haematol. 2021 Oct;195(1):113-1181. journals2021
Graham SlackLone W, Bouska A, Sharma S, Amador C, Saumyaranjan M, Herek TA, Heavican TB, Yu J, Lim ST, Ong CK, Slack GW, Savage KJ, Rosenwald A, Ott G, Cook JR, Feldman AL, Rimsza LM, McKeithan TW, Greiner TC, Weisenburger DD, Melle F, Motta G, Pileri S, Vose JM, Chan WC, Iqbal J. Genome-Wide miRNA Expression Profiling of Molecular Subgroups of Peripheral T-cell Lymphoma.Clin Cancer Res. 2021 Nov 1;27(21):6039-6053.1. journals2021
Graham SlackNowicka M, Hilton LK, Ashton-Key M, Hargreaves CE, Lee C, Foxall R, Carter MJ, Beers SA, Potter KN, Bolen CR, Klein C, Knapp A, Mir F, Rose-Zerilli M, Burton C, Klapper W, Scott DW, Sehn LH, Vitolo U, Martelli M, Trneny M, Rushton CK, Slack GW, Farinha P, Strefford JC, Oestergaard MZ, Morin RD, Cragg MS. Prognostic significance of FCGR2B expression for the response of DLBCL patients to rituximab or obinutuzumab treatment. Blood Adv. 2021 Aug 10;5(15):2945-2957.1. journals2021
Graham SlackDuns G, Viganò E, Ennishi D, Sarkozy C, Hung SS, Chavez E, Takata K, Rushton C, Jiang A, Ben-Neriah S, Woolcock BW, Slack GW, Hsi ED, Craig JW, Hilton LK, Shah SP, Farinha P, Mottok A, Gascoyne RD, Morin RD, Savage KJ, Scott DW, Steidl C. Characterization of DLBCL with a PMBL gene expression signature. Blood. 2021 Jul 15;138(2):136-148.1. journals2021
Graham SlackCollinge B, Ben-Neriah S, Chong L, Boyle M, Jiang A, Miyata-Takata T, Farinha P, Craig JW, Slack GW, Ennishi D, Mottok A, Meissner B, Chavez EA, Gerrie AS, Villa D, Freeman C, Savage KJ, Sehn LH, Morin RD, Mungall AJ, Gascoyne RD, Marra MA, Connors JM, Steidl C, Scott DW.The impact of MYC and BCL2 structural variants in tumors of DLBCL morphology and mechanisms of false-negative MYC IHC. Blood. 2021 Apr 22;137(16):2196-2208.1. journals2021
Graham SlackTwa DDW, Lee DG, Tan KL, Slack GW, Ben-Neriah S, Villa D, Connors JM, Sehn LH, Mottok A, Gascoyne RD, Scott DW, Steidl C, Savage KJ. Genomic predictors of central nervous system relapse in primary testicular diffuse large B-cell lymphoma. Blood. 2021 Mar 4;137(9):1256-1259.1. journals2021
Graham SlackSarkozy C, Hung SS, Chavez EA, Duns G, Takata K, Chong LC, Aoki T, Jiang A, Miyata-Takata T, Telenius A, Slack GW, Molina TJ, Ben-Neriah S, Farinha P, Dartigues P, Damotte D, Mottok A, Salles GA, Casasnovas RO, Savage KJ, Laurent C, Scott DW, Traverse-Glehen A, Steidl C. Mutational landscape of gray zone lymphoma. Blood. 2021 Apr 1;137(13):1765-1776.1. journals2021
Graham SlackFreeman CL, Savage KJ, Villa DR, Scott DW, Srour L, Gerrie AS, Brown MJ, Slack GW, Farinha P, Skinnider B, Morris J, Bénard F, Aquino-Parsons C, Lo A, Pickles T, Wilson DC, Tonseth P, Connors JM, Sehn LH. Long-term results of PET-guided radiation in patients with advanced-stage diffuse large B-cell lymphoma treated with R-CHOP.  Blood. 2021 Feb 18;137(7):929-938.1. journals2021
Gwen ClarkeMykhailova O, Turner TR, Olafson C, Howell A, Nahirniak SN, Wizniak J, Gerges HYN, Baldwin T, Clarke G, Acker JP. Hypothermic storage of leukoreduced red blood cells for greater than 21€‰days is a safe alternative to irradiation. Transfusion. 2021 Apr;61(4):1247-1257. doi: 10.1111/trf.16273. Epub 2021 Jan 22. PMID: 33481275.1. journals2021
Hélène CôtéAjaykumar A, Zhu M, Kakkar F, Brophy J, Bitnun A, Alimenti A, Soudeyns H, Saberi S, Albert AYK, Money DM, Côté HCF; CIHR Team in Cellular Aging and HIV Comorbidities in Women and Children (Children and Women: AntiRetrovirals and Markers of Aging [CARMA]). Elevated Blood Mitochondrial DNA in Early Life Among Uninfected Children Exposed to Human Immunodeficiency Virus and Combination Antiretroviral Therapy in utero. J Infect Dis. 2021 Feb 24;223(4):621-631. doi: 10.1093/infdis/jiaa410. SA1. journals2021
Hélène CôtéAjaykumar A, Wong GC, Yindom LM, McHugh G, Dauya E, Majonga E, Mujuru H, Ferrand RA, Rowland-Jones SL, Côté HCF. Shorter granulocyte telomeres among children and adolescents with perinatally-acquired HIV infection and chronic lung disease in Zimbabwe. Clin Infect Dis. 2020 Aug 8:ciaa11341. journals2021
Hélène CôtéPiske M, Budd MA, Qiu AQ, Maan EJ, Sauve LJ, Forbes JC, Alimenti A, Janssen PA, Money, DM, Cote HCF. Preterm Birth and Antiretroviral Exposure in Children HIV-Exposed Uninfected Born in British Columbia, Canada. Pediatr Infect Dis J. 2021 Mar 1;40(3):245-250 SA1. journals2021
Hélène CôtéToledo G, Cote HCF, Adler C, Thorne C, Goetghebuer T. The neurological development of children HIV-exposed and uninfected: are they thriving to their full potential? (review) Dev Med Child Neurol. 2021 Oct;63(10):1161-1170 CA1. journals2021
Hélène CôtéSwann SA, Kaida A, Brophy J, Campbell AR, Carter A, Elwood C, Gebrenedhen T, Gormley R, King E, Lee M, Lee V, Maan EJ, Magagula P, Nicholson V, Nyman S, Pang D, Pick N, Povshedna T, Prior JC, Singer J, Tognazzini S, Murray MCM, Cote HCF. The British Columbia CARMA-CHIWOS Collaboration (BCC3): Protocol for a community-collaborative cohort study examining healthy aging with and for women living with HIV. BMJ Open. 2021 Aug 6;11(8):e046558  SA1. journals2021
Hélène CôtéBecanovic K, Ashgar M, Gadawska I, Sachdeva, Walker D, Lazarowski RE, Franciosi S, Cote HCF, Leavitt BR. Age-related impairment of mitochondrial biogenesis in  brain and peripheral skeletal muscle in the YAC128 model of Huntington€™s disease.NPJ Aging Mech Dis. 2021 Oct 14;7(1):26. doi: 10.1038/s41514-021-00079-2. CA1. journals2021
Hélène CôtéSteele SL, Hsieh AYY, Gadawski I, Kroeun H, Barr SI, Devlin AM, Cote HCF, Karakochuk CD. Daily oral supplementation with 60 mg of elemental iron for 12 weeks alters blood mitochondrial DNA content but not leukocyte telomere length in Cambodian women of reproductive age. Nutrients. 2021 May 31;13(6):1877 CA1. journals2021
Hélène CôtéSwann SA, King EM, Cote HCF, Murray MCM. The role of the hypothalamic-pituitary-adrenal axis in the health and well-being of people living with HIV: A scoping review. (submitted to HIV Medicine, HIV-OA-10-2021-5669), invited resubmission of revised version in Jan 2022 CA1. journals2021
Hélène CôtéYang SY, Newcomb CE, Battle SL, Hsieh AYY, Chapman HL, Cote HCF, Arking DE. Rare instances of non-random dropout with the monochrome multiplex qPCR assay for mitochondrial DNA copy number. BioRXiv doi: https://doi.org/10.1101/2021.10.11.4639831. journals2021
Hélène CôtéCampbell AR, Gormley R, Nicholson V, Gebremedhen T, Pang D, Lee M, Tognazzini S, Egwalu A, Côté HCF, Murray MCM, Kaida A, on behalf of the BCC3 Research Team. Meaningful inclusion and training of Peer Research Associates by, with, and for women living with HIV: Teachings from the BC CARMA-CHIWOS Collaboration Study. 30th Annual Canadian Conference on HIV/AIDS Research (CAHR 2021), Virtual. May 2021. Poster Presentation1. journals2021
Hélène CôtéAbdullahi F, Becquart P, Vavasour I.M, Carruthers R, Traboulsee A, Sayao A, Schabas A, Devonshire V, Vilariño-Güell C, Côté HCF, Kalloger S, Laule C, Quandt J. Serum anti-ganglioside antibodies are present in multiple sclerosis and patterns of reactivity are associated with specific disease courses. (submitted to Journal of Neuroinflammation JNEU-D-21-00489) CA1. journals2021
Habib RazaviDiagnosis of indolent systemic mastocytosis in a patient with "seborrheic keratosis". Habib M Razavi , Samuel Krikler. Hematology, Transfusion and Cell Therapy (2021), HTCT-3242:2.1. journals2021
Habib RazaviA case of lymphocytic variant hypereosinophilic syndrome in an elderly patient. Habib M Razavi. Blood (2021); 137 (3): 429.1. journals2021
Habib RazaviBone Marrow Involvement by Aggressive B Cell Lymphoma Undetected by Aspirate Immunophenotyping. Habib M Razavi, J Hematol. (2021); 10(1): 14€“17.1. journals2021
Habib RazaviRazavi HM. Unusual Spherical Bodies in Bone Marrow of a Patient with Monoclonal Gammopathy of Undetermined Significance. Turk J Haematol. 2021 Jun 1;38(2):151-152. doi: 10.4274/tjh.galenos.2020.2020.0309. Epub 2020 Jun 16. PMID: 32539317; PMCID: PMC8171210.1. journals2021
Habib RazaviRapid acanthocytic schistocytosis and fulminant microangiopathic hemolysis as a preterminal event. Habib M Razavi, Clinical Case Reports. (2021); 9(5): e04247.1. journals2021
Habib RazaviA case of multiple myeloma with plasma cell cannibalism and cytophagocytosis. Julia Varghese, Habib M Razavi. eJHaem. (2021);2:303€“3041. journals2021
Hamid MasoudiMorgan A. Alford, Ka-Yee G. Choi, Michael J. Trimble, Hamid Masoudi,  Pavneet Kalsi, Daniel Pletzer,  and Robert E. W. Hancock 
Murine Model of Sinusitis Infection for Screening Antimicrobial and Immunomodulatory Therapies.
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Honglin LuoMohamud Y, Xue YC, Liu H, Ng CS, Bahreyni A, Jan E, Luo H*. The papain-like protease of coronaviruses cleaves ULK1 to disrupt host autophagy. Biochem Biophys Res Commun 2021; 540: 75-82 (IF=3.6)1. journals2021
Honglin LuoBahreyni A, Luo H, Ramezani M, Alibolandi M, Soheili V, Danesh NM, Sabeti-Ashjaei M, Abnous K, Taghdisi SM. A fluorescent sensing strategy for ultrasensitive detection of oxytetracycline in milk based on aptamer-magnetic bead conjugate, complementary strand of aptamer and picogreen. Spectrochimica Acta Part A 2021; 246: 119009 (IF=4.1)1. journals2021
Honglin LuoNg CS, Stobart CC, Luo H*. Innate immune evasion mediated by picornaviral 3Cpro: Possible lessons for coronaviral 3CLpro? Rev Med Virol 2021; 31: e2206 (IF=7.1)1. journals2021
Honglin LuoMohamud Y, Tang H, Xue YC, Liu H, Ng CS, Bahreyni A, Luo H*. Coxsackievirus B3 targets TFEB to disrupt lysosomal function. Autophagy 2021; 17(12): 3924-3938  - Featured in Science in the City (March 22, 2021) (IF=16.0)1. journals2021
Honglin LuoMohamud Y, Xue YC, Liu H, Ng CS, Bahreyni A, Luo H*. Autophagy receptor protein TAX1BP1/T6BP is a cellular substate of enteroviral proteinase. Front Microbiol  2021; 12: 647410 (IF=5.6)1. journals2021
Honglin LuoXue YC, Ng CS, Mohamud Y, Fung G, Liu H, Bahreyni A, Zhang J, Luo H*. FUS/TLS suppresses enterovirus replication and promotes anti-viral innate immune responses. J Virol 2021; 95(12): e00304-21 (IF=5.1)1. journals2021
Honglin LuoLiu H, Luo H*. Development of group B coxsackevirus as an oncolytic virus: Opportunities and challenges. Viruses  2021; 13(6): 1082 (IF=5.1)1. journals2021
Honglin LuoKlionsky DJ et al (Luo H, one of the co-authors). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy 2021; 17(1): 1-382 (IF=16.0)1. journals2021
Honglin LuoXiang P#, Mohamud Y#, Luo H*. SNAP47 interacts with ATG14 to promote VP1 conjugation and CVB3 propagation. (#Co-first author) Cells 2021; 10:2141 (IF=6.6)1. journals2021
Honglin LuoPablos I, Machado Y, Ramos de Jesus HC, Mohamud Y, Kappelhoff R, Lindskog C, Vlok M, Bell PA, Butler GS, Grin PM, Cao QT, Nguyen JP, Solis N, Abbina S, Rut W, Vederas JC, Szekely L, Szakos A, Drag M, Kizhakkedathu J, Mossman K, Hirota JA, Jan E, Luo H, Banerjee A, Overall CM. Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome. Cell Rep 2021; 37(4): 109892 (IF=9.4)1. journals2021
Ian BosdetSk, Wong, Alex D, Bosdet I, Hughesman C, Karsan A, Yip S, and Ho C. 2021. €œMET Exon 14 Skipping Mutation Positive Non-Small Cell Lung Cancer: Response to Systemic Therapy.€ Lung Cancer (Amsterdam, Netherlands) 1541. journals2021
Ian BosdetC, Mighton, Smith Ac, Mayers J, Tomaszewski R, Taylor S, Hume S, Agatep R, et al. 2021. €œData Sharing to Improve Concordance in Variant Interpretation across Laboratories: Results from the Canadian Open Genetics Repository.€ Journal of Medical Genetics, April. https://doi.org/10.1136/jmedgenet-2021-107738.1. journals2021
Ian BosdetEr, Starks, Swanson L, Docking Tr, Bosdet I, Munro S, Moore Ra, and Karsan A. 2021. €œAssessing Limit of Detection in Clinical Sequencing.€ The Journal of Molecular Diagnostics€¯: JMD 23 (4). https://doi.org/10.1016/j.jmoldx.2020.12.010.1. journals2021
Ian MackenzieChu SA, Flagan TM, Staffaroni AM, Jiskoot LC, Deng j, Spina S, Zhang L, Sturm VE, Yokoyama JS, Seeley WW, Papma JM, Geschwind DH, Rosen HJ, Boeve BF, Boxer AL, Heuer HW, Forsberg LK, Brushaber DE, Grossman M, Coppola G, Dickerson BC, Bordelon YM, Faber K, Feldman HH, Fields JA, Fong JC, Foroud T, Gavrilova RH, Ghoshal N, Graff-Radford NR, Hsiung GYR, Huey ED, Irwin DJ, Kantarci K, Kaufer DI, Karydas AM, Knopman DS, Kornak J, Kramer JH, Kukull WA, Lapid MI, Litvan I, Mackenzie IRA, Mendez MF, Miller BL, Onyike CU, Pantelyat AY, Rademakers R, Ramos EM, Roberson ED, Tartaglia MC, Tatton NA, Toga AW, Vetor A, Weintraub S, Wong B, Wszolek ZK, ARTFL/LEFFTDS Consortium, Van Swieten JC, Lee SE. Brain volumetric deficits in MAPT mutation carriers: a multisite study. Annals of Clinical and Translational Neurology 2021;8:95-110.1. journals2021
Ian MackenzieLin YC, Kumar MS, Ramesh N, Anderson EN, Nguyen AT, Kim B, Cheung S, McDonough JA, Skarnes WC, Gonzalez RL, Landers JE, Fawzi NL, Mackenzie IRA, Lee EB, Nickerson JA, Grunwald D, Pandey UB, Bosco DA. Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway. Nature Neuroscience 2021;24:1077-1088.1. journals2021
Ian MackenzieNeumann M, Lee EB, Mackenzie IR. Frontotemporal lobar degeneration TDP-43-immunoreactive pathological subtypes: clinical and mechanistic significance. Adv Exp Med Biol. 2021;1281:201-217.1. journals2021
Ian MackenzieReus LM, Pasaniuc B, Posthuma D, Boltz T; International FTD-Genomics Consortium, Pijnenburg YAL, Ophoff RA. Gene Expression Imputation Across Multiple Tissue Types Provides Insight Into the Genetic Architecture of Frontotemporal Dementia and Its Clinical Subtypes. Biol Psychiatry. 2021;89(8):825-835. 1. journals2021
Ian MackenzieRojas JC, Wang P, Staffaroni AM, Heller C, Cobigo Y, Wolf A, Goh SM, Ljubenkov PA, Heuer HW, Fong JC, Taylor JB, Veras E, Song L, Jeromin A, Hanlon D, Yu L, Khinikar A, Sivasankaran R, Kieloch A, Valentin MA, Karydas AM, Mitic LL, Pearlman R, Kornak J, Kramer JH, Miller BL, Kantarci K, Knopman DS, Graff-Radford N, Petrucelli L, Rademakers R, Irwin DJ, Grossman M, Ramos EM, Coppola G, Mendez MF, Bordelon Y, Dickerson BC, Ghoshal N, Huey ED, Mackenzie IR, Appleby BS, Domoto-Reilly K, Hsiung GR, Toga AW, Weintraub S, Kaufer DI, Kerwin D, Litvan I, Onyike CU, Pantelyat A, Roberson ED, Tartaglia MC, Foroud T, Chen W, Czerkowicz J, Graham DL, van Swieten JC, Borroni B, Sanchez-Valle R, Moreno F, Laforce R, Graff C, Synofzik M, Galimberti D, Rowe JB, Masellis M, Finger E, Vandenberghe R, de Mendonça A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Otto M, Sorbi S, Cash DM, Convery RS, Bocchetta M, Foiani M, Caroline V G, Peakman G, Russell L, Swift I, Todd E, Rohrer JD, Boeve BF, Rosen HJ, Boxer AL. Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration. Neurology. 2021;96(18):e2296-e2312.1. journals2021
Ian MackenzieBarker MS, Manoochehri M, Rizer SJ, Appleby BS, Brushaber D, Dev SI, Devick KL, Dickerson BC, Fields JA, Foroud TM, Forsberg LK, Galasko DR, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Hsiung GY, Kornak J, Litvan I, Mackenzie IR, Mendez MF, Pascual B, Rankin KP, Rascovsky K, Staffaroni AM, Tartaglia MC, Weintraub S, Wong B, Boeve BF, Boxer AL, Rosen HJ, Goldman J, Huey ED, Cosentino S, ALLFTD consortium. Recognition memory and divergent cognitive profiles in prodromal genetic frontotemporal dementia. Cortex 2021;139:99-115.1. journals2021
Ian MackenziePopuri K, Beg MF, Balachandar R, Wang L, Sossi V, Jacova C, Baker M, Shahinfard E, Rademakers R, Mackenzie IRA, Hsiung GYR. FDG-PET in presymptomatic C9orf72 mutation carriers. Neuroimage Clin 2021 Apr 25;31:102687. 1. journals2021
Ian MackenzieFerreira N, Richner M, van der Laan A, Bergholdt Jul Christiansen I, Vægter CB, Nyengaard JR, Halliday GM, Weiss J, Giasson BI, Mackenzie IR, Jensen PH, Jan A. Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy. Brain Commun 2021;3:fcab104. 1. journals2021
Ian MackenzieChatterjee A, Hirsch-Reinshagen V, Moussavi SA, Ducharme B, Mackenzie IR, Hsiung GR. Clinico-pathological comparison of patients with autopsy-confirmed Alzheimer's disease, dementia with Lewy bodies, and mixed pathology. Alzheimers Dement 2021;13(1):e12189.1. journals2021
Ian MackenzieDelaidelli A, Richner M, Jiang L, van der Laan A, Bergholdt Jul Christiansen I, Ferreira N, Nyengaard JR, Vægter CB, Jensen PH, Mackenzie IR, Sorensen PH, Jan A. α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response. Acta Neuropathol Commun. 2021 Jun 6;9:105. 1. journals2021
Ian MackenzieWu Y, Shao W, , Todd TW, Tong J, Yue M, Koga S, Castanedes-Casey M, Librero AL, Lee CW, Mackenzie IR, Dickson DW, Zhang YJ, Petrucelli L, Prudencio M. Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD. Cell Report 2021; 36:109581.1. journals2021
Ian MackenziePobran TD, Yang D, Mackenzie IRA, DeMarco ML. Aptamer-based enrichment of TDP-43 from human cells and tissues with quantification by HPLC-MS/MS. J Neurosci Methods. 2021 Aug 29;363:109344. 1. journals2021
Inna SekirovStein DR, Osiowy C, Gretchen A, Thorlacius L, Fudge D, Lang A, Sekirov I, Morshed M, Levett PN, Tran V, Kus JV, Gubbay J, Mohan V, Charlton C, Kanji JN, Tipples G, Serhir B, Therrien C, Roger M, Jiao L, Zahariadis G, Needle R, Gilbert L, Desnoyers G, Garceau R, Bouhtiauy I, Longtin J, El-Gabalawy N, Dibernardo A, Lindsay LR, Drebot M; Canadian Public Health Laboratory Network (CPHLN) Serology Task Force. Evaluation of commercial SARS-CoV-2 serological assays in Canadian public health laboratories. Diagn Microbiol Infect Dis. 2021 Apr 24;101(3):115412. doi: 10.1016/j.diagmicrobio.2021.115412. Epub ahead of print. PMID: 34425450; PMCID: PMC8377389.1. journals2021
Inna SekirovSekirov I, Barakauskas VE, Simons J, Cook D, Bates B, Burns L, Masud S, Charles M, McLennan M, Mak A, Chahil N, Vijh R, Hayden A, Goldfarb D, Levett PN, Krajden M, Morshed M. SARS-CoV-2 serology: Validation of high-throughput chemiluminescent immunoassay (CLIA) platforms and a field study in British Columbia. J Clin Virol. 2021 Sep;142:104914. doi: 10.1016/j.jcv.2021.104914. Epub 2021 Jul 16. PMID: 34304088; PMCID: PMC8282439.1. journals2021
Inna SekirovSekirov I, Petric M, Carruthers E, Lawrence D, Pidduck T, Kustra J, Laley J, Lee MK, Chahil N, Mak A, Levett PN, Mendoza E, Wood H, Drebot M, Krajden M, Morshed M. Performance comparison of micro-neutralization assays based on surrogate SARS-CoV-2 and WT SARS-CoV-2 in assessing virus-neutralizing capacity of anti-SARS-CoV-2 antibodies. Access Microbiol. 2021 Aug 26;3(8):000257. doi: 10.1099/acmi.0.000257. PMID: 34888485; PMCID: PMC8650845.1. journals2021
Inna SekirovReich N, Lowe CF, Puddicombe D, Matic N, Greiner J, Simons J, Leung V, Chu T, Naik H, Myles N, Burns L, Romney MG, Ritchie G, Champagne S, Dooley K, Sekirov I, Stefanovic A. Repeat virological and serological profiles in hospitalized patients initially tested by nasopharyngeal RT-PCR for SARS-CoV-2. J Med Virol. 2021 Jul 23:10.1002/jmv.27227. doi: 10.1002/jmv.27227. Epub ahead of print. PMID: 34297350; PMCID: PMC8426995.1. journals2021
Inna SekirovCharlton C, Kanji J, Tran V, Kus J, Gubbay J, Osiowy C, Robinson J, Sekirov I, Drebot M, Hatchette T, Stein D, El-Gabalawy N, Lang A, Jiao L, Levett P, Wood H, Therrien C, Lindsay LR, Morshed M, Forbes J, Dibernardo A. Practical guidance for clinical laboratories for SARS-CoV-2 serology testing. Can Commun Dis Rep. 2021 May 7;47(4):171-183. doi: 10.14745/ccdr.v47i04a01. PMID: 34035663; PMCID: PMC8127682.1. journals2021
Inna SekirovNikiforuk AM, Kuchinski KS, Twa DDW, Lukac CD, Sbihi H, Basham CA, Steidl C, Prystajecky NA, Jassem AN, Krajden M, Patrick DM, Sekirov I. The contrasting role of nasopharyngeal angiotensin converting enzyme 2 (ACE2) transcription in SARS-CoV-2 infection: A cross-sectional study of people tested for COVID-19 in British Columbia, Canada. EBioMedicine. 2021 Apr;66:103316. doi: 10.1016/j.ebiom.2021.103316. Epub 2021 Apr 2. PMID: 33819740; PMCID: PMC8016616.1. journals2021
Inna SekirovMorshed M, Sekirov I, McLennan M, Levett PN, Chahil N, Mak A, Carruthers E, Pidduck T, Kustra J, Laley J, Lee MK, Chu K, Burgess F, Vijh R, Willis L, Wada R, Blancaflor R, Boraston S, Hayden A, Krajden M. Comparative Analysis of Capillary vs Venous Blood for Serologic Detection of SARS-CoV-2 Antibodies by RPOC Lateral Flow Tests. Open Forum Infect Dis. 2021 Jan 28;8(3):ofab043. doi: 10.1093/ofid/ofab043. PMID: 33723509; PMCID: PMC7928643.1. journals2021
Inna SekirovMajdoubi A, Michalski C, O'Connell SE, Dada S, Narpala S, Gelinas J, Mehta D, Cheung C, Winkler DF, Basappa M, Liu AC, Görges M, Barakauskas VE, Irvine M, Mehalko J, Esposito D, Sekirov I, Jassem AN, Goldfarb DM, Pelech S, Douek DC, McDermott AB, Lavoie PM. A majority of uninfected adults show preexisting antibody reactivity against SARS-CoV-2. JCI Insight. 2021 Apr 22;6(8):e146316. doi: 10.1172/jci.insight.146316. PMID: 33720905; PMCID: PMC8119195.1. journals2021
Inna SekirovTwa DD, Lukac CD, Kuchinski K, Nikiforuk A, Sekirov I. Neutrophils as a pallbearer for SARS-CoV-2 disease burden. Lancet Microbe. 2021 Feb;2(2):e56. doi: 10.1016/S2666-5247(21)00002-1. Epub 2021 Feb 2. PMID: 33655231; PMCID: PMC7906692.1. journals2021
Inna SekirovVijh R, Ghafari C, Hayden A, Schwandt M, Sekirov I, Morshed M, Levett P, Krajden M, Boraston S, Daly P, Lysyshyn M, Harding J, McLennan M, Chahil N, Mak A, McKee G. Serological survey following SARS-COV-2 outbreaks at long-term care facilities in metro Vancouver, British Columbia: Implications for outbreak management and infection control policies. Am J Infect Control. 2021 May;49(5):649-652. doi: 10.1016/j.ajic.2020.10.009. Epub 2020 Oct 18. PMID: 33086096; PMCID: PMC7568771.1. journals2021
Inna SekirovChiang LY, Baumann B, Romanowski K, Kumar D, Campbell JR, Djurdjev O, Morshed M, Sekirov I, Cook VJ, Levin A, Johnston JC. Latent Tuberculosis Therapy Outcomes in Dialysis Patients: A Retrospective Cohort. Am J Kidney Dis. 2021 May;77(5):696-703. doi: 10.1053/j.ajkd.2020.06.017. Epub 2020 Aug 17. PMID: 32818551.1. journals2021
Inna SekirovLowe CF, Kiaii M, Aparicio L, Chinybaeva L, Coughlin S, Sekirov I, Morshed MG, Leung V. Risk following a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) exposure from a nocturnal hemodialysis patient utilizing continuous positive airway pressure (CPAP). Infect Control Hosp Epidemiol. 2021 Apr;42(4):491-492. doi: 10.1017/ice.2020.291. Epub 2020 Jun 11. PMID: 32522296; PMCID: PMC7308625.1. journals2021
Inna SekirovMcClymont E, Elwood C, Sekirov I, Morshed M, Levett P, Liu A, Jassem A, Sbihi H, Ogilvie G, Krajden M, Money D. Population SARS-CoV-2 Seroprevalence Using Antenatal Serum Samples in British Columbia, Canada. J Obstet Gynaecol Can. 2021 Nov;43(11):1242-1243. doi: 10.1016/j.jogc.2021.06.001. PMID: 34758903; PMCID: PMC8572370.1. journals2021
Inna SekirovValcourt EJ, Manguiat K, Robinson A, Lin YC, Abe KT, Mubareka S, Shigayeva A, Zhong Z, Girardin RC, DuPuis A, Payne A, McDonough K, Wang Z, Gasser R, Laumaea A, Benlarbi M, Richard J, Prévost J, Anand SP, Dimitrova K, Phillipson C, McGeer A, Gingras AC, Liang C, Petric M, Sekirov I, Morshed M, Finzi A, Drebot M, Wood H. Evaluating Humoral Immunity against SARS-CoV-2: Validation of a Plaque-Reduction Neutralization Test and a Multilaboratory Comparison of Conventional and Surrogate Neutralization Assays. Microbiol Spectr. 2021 Dec 22;9(3):e0088621. doi: 10.1128/Spectrum.00886-21. Epub 2021 Nov 17. PMID: 34787495; PMCID: PMC8597631.1. journals2021
Inna SekirovEckbo EJ, Rodrigues M, Hird T, Ng M, Lam K, Sekirov I. Needle in a Haystack: Looking for Tuberculosis in a Low Incidence Setting. JAMMI. 2021 Mar;6(1):49-54. doi: 10.3138/jammi-2020-0022. 1. journals2021
Inna SekirovSherwood KR, Nicholl DDM, Fenninger F, Wu V, Wong P, Benedicto V, Cina DP, Wang M, Pobran TD, De Marco ML, Márquez AC, Jassem AN, Sekirov I, Morshed MG, Bardi M, Sekhon M, Keown P, Kadatz M, Lan JH. Comprehensive Immune Profiling of a Kidney Transplant Recipient With Peri-Operative SARS-CoV-2 Infection: A Case Report. Front Immunol. 2021 Sep 22;12:753558. doi: 10.3389/fimmu.2021.753558. PMID: 34630432; PMCID: PMC8492986.1. journals2021
Inna SekirovReich N, Lowe CF, Puddicombe D, Matic N, Greiner J, Simons J, Leung V, Chu T, Naik H, Myles N, Burns L, Romney MG, Ritchie G, Champagne S, Dooley K, Sekirov I, Stefanovic A. Diagnostic accuracy of RT-PCR for detection of SARS-CoV-2 compared to a "composite reference standard" in hospitalized patients. medRxiv. 2021.02.18.21252016. doi: 10.1101/2021.02.18.21252016.1. journals2021
Jacqueline QuandtVilariño-Güell G, Encarnacion M, Bernales CQ, Kamma E, Becquart P, Quandt JA. Transcriptome analysis of the NR1H3 mouse model of multiple sclerosis reveals a pro-inflammatory phenotype with dysregulation of lipid metabolism and immune response genes BioRxiv Mar 17, 2021  doi: https://doi.org/10.1101/2021.03.17.4356781. journals2021
Jacqueline QuandtKamma A, Becquart P, Traboulsee A, Schabas AJ, Vavasour IM, Laule C, Vilariño-Güell C, Quandt JA. Elevated levels of serum CD5 antigen-like protein distinguish secondary progressive multiple sclerosis from other disease subtypes Mult. Scler. Rel. Dis. 2021 Sep 20;56:103269. doi: 10.1016/j.msard.2021.103269 SA (IF 4.4)1. journals2021
Jacqueline QuandtMarrie RA, Allegretta M, Barcellos LF, Bebo B, Calabresi P, Correale J, Davis B, De Jager PL, Gasperi C, Greenbaum C, Helme A, Hemmer B, Kanellis P, Kostich W, Landsman D, Lebrun-Frenay C, Makhani N, Munger K, Okuda DT, Ontaneda D, Postuma R, Quandt JA, Roman S, Saidha S, Sormani M-P, Strum J, Valentine P, Walton C, Zackowski KM, Zhao Y, Tremlett T. From the Prodromal Stage of Multiple Sclerosis to Disease Prevention: Developing a Roadmap. CA. Nat. Rev. Neurol.  NRNEUROL-21-351V1 Submitted Nov 8, 2021 Under Review (IF 27) 1. journals2021
Jacqueline QuandtAbdullahi F, Becquart P, Vilarino-Guell C, Carruthers R, Traboulsee A, Sayao A-L, Schabas A, Devonshire V, Vavasour I, Cote H, Kalloger S, Laule C, Quandt JA. Serum anti-ganglioside antibodies are present in multiple sclerosis patients and patterns of reactivity are associated with specific disease courses SA J Neuroinflam Submitted June 2021 JNEU-D-21-00489 Under Revision (IF 7.5)1. journals2021
Jacqueline QuandtVavasour IM, Becquart P, Gill J, Zhao F, Yik JT, Traboulsee A, Carruthers RL, Kolind SH, Schabas AJ, Sayao A-L, Devonshire V, Tam R, Moore GRW, Stukas S, Wellington C, Quandt JA, Li DKB, Laule C. Diffusely abnormal white matter in clinically isolated syndrome is associated with parenchymal loss and elevated neurofilament levels. CA. Mult. Scler. Relat. Disord. 2021 doi.org/10.1016/j.msard.2021.103422 CA (IF 4.4) 1. journals2021
James LanTran JN, Gunther OP, Sherwood KR, Fenninger F, Allan LL, Lan JH, Sapir-Pichhadze R, Duquesnoy R, claas F, Marsh SGE, McMaster R, Keown PA. Next-Generation Sequencing Defines Donor and Recipient HLA B-Cell Epitope Frequencies for Prospective Matching in Transplantation. Nature Commun Biol 4, 583 (2021). https://doi.org/10.1038/s42003-021-01989-3.1. journals2021
James LanLan JH, Kadatz M, Chang DT, Gill J, Gebel HM, Gill JS. Pre-transplant calculated panel reactive antibody in the absence of donor specific antibody and kidney allograft survival. Clinical Journal of the American Society of Nephrology 2021;16(2):275-283. 1. journals2021
James LanEvans RDR, Lan JH, Kadatz M, Brar S, Chang DT, McMichael L, Gill J, Gill JS: Use and outcomes of induction therapy in well-matched kidney transplant recipients. Clin J Am Soc Nephrol 17: 271€“279, 2022 (accompanied by editorial CJASN 17: 173€“175, 2022. doi: https://doi.org/10.2215/CJN.16591221).1. journals2021
James LanDavey C, Bissonnette ML, Lan, JH, Harriman, D, Nguan, C. A Donor With Green Kidneys€”To Transplant or Not to Transplant: A Case Report, Transplantation Direct: September 2021 - Volume 7 - Issue 9 - p e739 doi: 10.1097/TXD.0000000000001198.1. journals2021
James LanSherwood K, Nicholl D, Fenninger F, Wu V, Wong P, Benedicto V, Cina D, Wang M, Pobran T, De Marco M, Márquez A, Jassem A, Sekirov I, Morshed M, Bardi M, Sekhon M, Keown P, Kadatz M, Lan JH. Comprehensive Immune Profiling of a Kidney Transplant Recipient With Peri-Operative SARS-CoV-2 Infection: A Case Report. Front. Immunol 2021. 12:753558. doi: 10.3389/fimmu.2021.7535581. journals2021
James LanKadatz M, Lan JH, Brar S, Vaishnav S, Chang DT, Gill J, Gill JS. Transplantation of patients with long dialysis vintage in the current deceased donor kidney allocation system. Am J Kidney Dis. Accepted.1. journals2021
James LanSherwood K, Tran J, Gunther OP, Lan JH, Aiyegbusi O, Liwski R, Sapir-Pichhadze R, Bryan S, Caufield T, Keown P. Genome Canada Precision Medicine Process for Structured National Implementation of Epitope Matching in Renal Transplantation. Human Immunology. In Press.1. journals2021
James LanTran J, Gunther O, Sherwood K, Sapir-Pichhadze R, Lan JH, and Paul Keown on behalf of the Genome Canada Transplant Consortium. Towards Epitope Matching in Transplantation. American Society of Histocompatibility and Immunogenetics Quarterly 2021.1. journals2021
James ZlosnikCoulon PML, Wagner D, Zlosnik JEA, Deziel E. Environmental isolates from the Burkholderia cepacia complex are more likely to possess the hmqABCDEFG operon and to produce HMAQs than clinical isolates. Microbiol Spectr. 2021 Sep 3;9(1):e0012721.1. journals2021
Jayachandran KizhakkedathuKai Yu, Amal Alzahrani, Sara Khoddami, Demian Ferreira, Kymora B Scotland, John TJ Cheng, Hossein Yazdani-Ahmadabadi, Yan Mei, Arshdeep Gill, Lily E Takeuchi, Edbert Yeung, Dana Grecov, Robert EW Hancock, Ben H Chew, Dirk Lange, Jayachandran N Kizhakkedathu. (2021). Self-limiting Mussel Inspired Thin Antifouling Coating with Broad Spectrum Resistance to Biofilm Formation to Prevent Catheter Associated Infection in Mouse and Porcine Models. Advanced Healthcare Materials. 2001573: 2001573.1. journals2021
Jayachandran KizhakkedathuAbbasi Usama, Abbina Srinivas, Gill Arshdeep, Bhagat Vriti, Jayachandran N Kizhakkedathu. (2021). A facile colorimetric method for the quantification of labile iron pool and total iron in cells and tissue specimens. Scientific Reports. 11(1): 6008.1. journals2021
Jayachandran KizhakkedathuKatharina Achazi, Rainer Haag, Matthias Ballauff, Jens Dernedde, Jayachandran N Kizhakkedathu, Dusica Maysinger, Gerd Multhaup. (2021). Understanding the interaction of polyelectrolyte architectures with proteins and biosystems. Angewandte Chemie International Edition. 60(8): 3882-3904.1. journals2021
Jayachandran KizhakkedathuXin Song, Haifeng Ji, Yupei Li, Yuqin Xiong, Li Qiu, Rui Zhong, Meng Tian, Jayachandran N. Kizhakkedathu, Baihai Su, Qiang Wei, Weifeng Zhao, Changsheng Zhao. (2021). Transient blood thinning during extracorporeal blood purification via the inactivation of coagulation factors by hydrogel microspheres. Nature Biomedical Engineering. 5: 1-14.1. journals2021
Jayachandran KizhakkedathuErika MJ Siren, Haiming D Luo, Sargun Bajaj, Jordan MacKenzie, Masoud Daneshi, D Mark Martinez, Edward M Conway, Karen C Cheung, Jayachandran N Kizhakkedathu (2021). An improved in vitro model for studying the structural and functional properties of the endothelial glycocalyx in arteries, capillaries and veins. The FASEB Journal, 35, e216431. journals2021
Jayachandran KizhakkedathuShadan Li, Zhongli Huang, Xiaowei Li, Youguang Zhao, Xin Jiang, Yang Wen, Hao Luo, Liang Wang, Qiunong Guan, Irina Cafeeva, Donald E Brooks, Christopher YC Nguan, Jayachandran N Kizhakkedathu, Caigan Du (2021) Evaluation of hyperbranched polyglycerol for cold perfusion and storage of donor kidneys in a pig model of kidney autotransplantation. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 109, 853-8631. journals2021
Jayachandran KizhakkedathuFatih Demir, Jayachandran N Kizhakkedathu, Markus M Rinschen, Pitter F Huesgen (2021) MANTI: Automated Annotation of Protein N-Termini for Rapid Interpretation of N-Terminome Data Sets. Analytical Chemistry 93, 5596-56051. journals2021
Jayachandran KizhakkedathuUsama Abbasi, Srinivas Abbina, Arshdeep Gill, Lily E Takuechi, Jayachandran N. Kizhakkedathu. (2021) The Role of Iron in the Molecular Pathogenesis of Diseases and Therapeutic Opportunities. ACS Chemical Biology 16, 6, 945€“9721. journals2021
Jayachandran KizhakkedathuErika M.J.Siren, Haiming D. Luo, Ashani Montgomery, Winnie Enns, Haisle Moon, Lyann Sim, Jiao Jing Wang, Qiunong Wang, Zheng Jenny Zhang, Caigan Du, Stephen G. Withers, Jonathan Choy, Jayachandran N. Kizhakkedathu. (2021). Prevention of vascular-allograft rejection by protecting the endothelial glycocalyx with immunosuppressive polymers. Nature Biomedical Engineering 5 (10), 1202-1216.1. journals2021
Jayachandran KizhakkedathuKai Yu, Amal Alzahrani, Sara Khoddami, John T. J. Cheng, Yan Mei, Arshdeep Gill, Haiming D. Luo, Evan F. Haney, Kai Hilpert, Robert E.W. Hancock, Dirk Lange and Jayachandran N. Kizhakkedathu (2021). Rapid assembly of infection-resistant coatings: Screening and identification of antimicrobial peptides works in cooperation with an antifouling background. ACS Applied Materials & Interfaces 13 (31), 36784-3679.1. journals2021
Jayachandran KizhakkedathuJayachandran N Kizhakkedathu, Edward M Conway (2021). Biomaterial and cellular implants: foreign surfaces where immunity and coagulation meet. Blood ( in press). https://doi.org/10.1182/blood.20200072091. journals2021
Jayachandran KizhakkedathuXiaoxiao Zhao, Behrooz Khatir, Kiana Mirshahidi, Kai Yu, Jayachandran N Kizhakkedathu, Kevin Golovin (2021) Macroscopic evidence of the liquidlike nature of nanoscale polydimethylsiloxane brushes. ACS Nano 15 (8), 13559-13567.1. journals2021
Jayachandran KizhakkedathuIsabel Pablos, Yoan Machado, Hugo C Ramos de Jesus, Yasir Mohamud, Reinhild Kappelhoff, Cecilia Lindskog, Marli Vlok, Peter A Bell, Georgina S Butler, Peter M Grin, Quynh T Cao, Jenny P Nguyen, Nestor Solis, Srinivas Abbina, Wioletta Rut, John C Vederas, Laszlo Szekely, Attila Szakos, Marcin Drag, Jayachandran N Kizhakkedathu, Karen Mossman, Jeremy A Hirota, Eric Jan, Honglin Luo, Arinjay Banerjee, Christopher M Overall (2021) Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome. Cell Reports 37 (4), 109892.1. journals2021
Jayachandran KizhakkedathuMatthew Drayton, Morgan A Alford, Daniel Pletzer, Evan F Haney, Yoan Machado, Haiming D Luo, Christopher M Overall, Jayachandran N Kizhakkedathu, Robert EW Hancock, Suzana K Straus (2021) Enzymatically releasable polyethylene glycol€“host defense peptide conjugates with improved activity and biocompatibility. Journal of Controlled Release 339, 220-2311. journals2021
Jayachandran KizhakkedathuHan Hung Yeh, Kai Yu, Sreeparna Vappala, Manu Thomas Kalathottukaren, Srinivas Abbina, Haiming D Luo, Dana Grecov, Jayachandran N Kizhakkedathu (2021)Rheological and clot microstructure evaluation of heparin neutralization by UHRA and protamine. Journal of the Mechanical Behavior of Biomedical Materials. 124, 1048511. journals2021
Jennifer GrantYassi A, Grant JM, Lockheart K, Barker S, Sprague S, Okpani A, Wong T, Daly P, Henderson W, Lubin S, Kim Sing C, Infection control, occupational and public health measures including mRNA-based vaccination against SARS-CoV-2 infections to protect healthcare workers from variants of concern: A 14-month observational study using surveillance data. PLOS One, 6(7): e0254920. Jul 20211. journals2021
Jennifer GrantGerman G, Frenette C, Caissy JA, Grant JM et al., The 2018 Global Point Prevalence Survey of antimicrobial consumption and resistance in 47 Canadian hospitals: a cross-sectional survey, CMAJ open. 9(4):1242-51. Dec 20211. journals2021
Jennifer GrantBrittany Buffone BSc, Yu-Chen Lin PharmD, Jennifer Grant MDCM, β-lactam exposure outcome among patients with a documented allergy to penicillins post-implementation of a new electronicmedical record system and alerting rules. JAMMI. In press.1. journals2021
Jennifer GrantGrant, JM, Song W, Shajari S, Mak R, Meikle A, Partovi N, Masri BA, Lau TTY, Safety of administering cefazolin versus other antibiotics in penicillin-allergic patients for surgical prophylaxis at a major Canadian teaching hospital, Surgery, [Accepted for publicaion March 6, 2021]1. journals2021
Jessica SaundersNguyen MT, Saunders J, Pacheco MC, Stacey A. Progressive Pre-Retinal Fibrosis with Late, Ossifying, Proliferative Retinopathy Following Treatment for Retinoblastoma. Ocular Oncology and Pathology 2021,7(1) p. 44-471. journals2021
Jessica SaundersSaunders J, Callejas Salgado A, Ting J, Mamman C, Terry J, Bush J. Quantifying Proximal Collecting Tubule Deficiency in Angiotensin-Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Fetopathy.Pediatric and Developmental Pathology 2021, 24(5) p. 438-4441. journals2021
Joanne WrightChurg A, Ryerson CJ, Wright JL. Fibroblast Foci and Patchy Fibrosis Do Not Separate Usual Interstitial Pneumonia From Fibrotic Hypersensitivity Pneumonitis in Transbronchial Cryobiopsies. Arch Pathol Lab Med. 2021 Nov 1;145(11):1325-1326. doi: 10.5858/arpa.2021-0234-LE. PMID: 34673908.1. journals2021
Joanne WrightNaso JR, Levine AB, Farahani H, Chirieac LR, Dacic S, Wright JL, Lai C, Yang HM, Jones SJM, Bashashati A, Yip S, Churg A. Deep-learning based classification distinguishes sarcomatoid malignant mesotheliomas from benign spindle cell mesothelial proliferations. Mod Pathol. 2021 Nov;34(11):2028-2035. doi: 10.1038/s41379-021-00850-6. Epub 2021 Jun 10. PMID: 34112957.1. journals2021
Joanne WrightChurg A, Wright JL. Morphologic Features of Fibrotic Hypersensitivity Pneumonitis in Transbronchial Cryobiopsies Versus Video-Assisted Thoracoscopic Biopsies: An In Silico Study. Arch Pathol Lab Med. 2021 Apr 1;145(4):448-452. doi: 10.5858/arpa.2020-0176-OA. PMID: 32886735.1. journals2021
Jocelyn SrigleyGadkar VJ, Goldfarb DM, Young V, Watson N, Al-Rawahi GN, Srigley JA, Tilley P. Development and validation of a new triplex real-time quantitative reverse Transcriptase-PCR assay for the clinical detection of SARS-CoV-2. Mol Cell Probes. 2021 Aug;58:101744. doi: 10.1016/j.mcp.2021.101744. Epub 2021 Jun 4. PMID: 34089805; PMCID: PMC8176879.1. journals2021
Jocelyn SrigleyBryce EA, Velapatino B, Donnelly-Pierce T, Khorami HA, Wong T, Dixon R, Asselin E, McGeer A, Srigley JA, Katz K. Antimicrobial efficacy and durability of copper formulations over one year of hospital use. Infect Control Hosp Epidemiol. 2021 Mar 15:1-9. doi: 10.1017/ice.2021.52. Epub ahead of print. PMID: 33715655.1. journals2021
Jocelyn SrigleyGoldfarb DM, Tilley P, Al-Rawahi GN, Srigley JA, Ford G, Pedersen H, Pabbi A, Hannam-Clark S, Charles M, Dittrick M, Gadkar VJ, Pernica JM, Hoang LMN. Self-Collected Saline Gargle Samples as an Alternative to Health Care Worker-Collected Nasopharyngeal Swabs for COVID-19 Diagnosis in Outpatients. J Clin Microbiol. 2021 Mar 19;59(4):e02427-20. doi: 10.1128/JCM.02427-20. PMID: 33514627; PMCID: PMC8092743.1. journals2021
Jocelyn SrigleyGoldfarb DM, Tilley P, Al-Rawahi GN, Srigley JA, Ford G, Pedersen H, Pabbi A, Hannam-Clark S, Charles M, Dittrick M, Gadkar VJ, Pernica JM, Hoang LMN. Self-Collected Saline Gargle Samples as an Alternative to Health Care Worker-Collected Nasopharyngeal Swabs for COVID-19 Diagnosis in Outpatients. J Clin Microbiol. 2021 Mar 19;59(4):e02427-20. doi: 10.1128/JCM.02427-20. PMID: 33514627; PMCID: PMC8092743.1. journals2021
Jocelyn SrigleyLee Z, Lo J, Luan Y, Fernando J, Johannesen D, Masuda C, Swallow T, Srigley JA. Patient, family, and visitor hand hygiene knowledge, attitudes, and practices at pediatric and maternity hospitals: A descriptive study. American Journal of Infection Control 2021;49(8):1000-7. doi: 10.1016/j.ajic.2021.02.015.1. journals2021
Jocelyn SrigleyLo J, Luan YL, Lee Z, Jacques L, Krueckl L, Srigley JA. Improving patient, family, and visitor hand hygiene on a pediatric oncology/hematology/bone marrow transplant unit. Canadian Journal of Infection Control 2021;36(2):94-96.1. journals2021
Jonathan BushHoldhof D, Johann PD, Spohn M, Bockmayr M, Safaei S, Joshi P, Masliah-Planchon J, Ho B, Andrianteranagna M, Bourdeaut F, Huang A, Kool M, Upadhyaya SA, Bendel AE, Indenbirken D, Foulkes WD, Bush JW, Creytens D, Kordes U, Fruhwald MC, Hasselblatt M, Schuller U. Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases. Acta Neuropathologica. 2021; 141(2): 291-301. PMID: 33331994.1. journals2021
Jonathan BushAndrianteranagna M, Cyrta J, Masliah-Planchon J, Nemes K, Corsia A, Leruste A, Holdhof D, Kordes U, Orbach D, Corradini N, Entz-Werle N, Pierron G, Castex MP, Brouchet A, Weingertner N, Ranchere D, Freneaux P, Delattre O, Servant N, Bush J, Leary A, Fruhwald MC, Schuller U, Bourdeaut F. SMARCA4-deficient rhabdoid tumors show intermediate molecular features between SMARCB1-deficient rhabdoid tumors and small cell carcinomas of the ovary, hypercalcemic type. The Journal of Pathology. 2021; 255(1): 1-15. PMID: 33999421.1. journals2021
Jonathan BushSaunders J, Callejas Salgado AM, Ting JY, Mammen C, Terry J, Bush JW. Quantifying proximal collecting tubule deficiency in angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker fetopathy. Pediatric and Developmental Pathology. 2021; 24(5): 438-444. PMID: 34082612.1. journals2021
Joshua DublandDubland JA, Allahverdian S, Besler KJ, Ortega C, Wang Y, Pryma CS, Boukais K, Chan T, Seidman MA, Francis GA*. Low LAL (Lysosomal Acid Lipase) Expression by Smooth Muscle Cells Relative to Macrophages as a Mechanism for Arterial Foam Cell Formation. Arterioscler Thromb Vasc Biol. 2021 Jun;41(6):e354-e368. doi: 10.1161/ATVBAHA.120.316063. Epub 2021 Apr 1. PMID: 33792344. (FA)1. journals2021
Joshua DublandFeldman-Kiss D, Li D, Cleve R, Sinclair G, Dubland JA, Wang L*. Interference of ketone bodies on laboratory creatinine measurement in children with DKA: a call for change in testing practices. Pediatr Nephrol. 2021 Nov 10. doi: 10.1007/s00467-021-05324-0. Epub ahead of print. PMID: 34757480. (CA)1. journals2021
Joshua DublandDubland JA*, Rakic B, Vallance H, Sinclair G. Analysis of 2-methylcitric acid, methylmalonic acid, and total homocysteine in dried blood spots by LC-MS/MS for application in the newborn screening laboratory: A dual derivatization approach. J Mass Spectrom Adv Clin Lab. 2021 Mar 17;20:1-10. doi: 10.1016/j.jmsacl.2021.03.001. PMID: 34820666; PMCID: PMC8601015. (FA, SA)1. journals2021
Joshua DublandDubland JA*. Role of inflammatory cytokines in genesis and treatment of atherosclerosis. Looking at foam cells through a different lens. Trends Cardiovasc Med. 2021 Mar 3:S1050-1738(21)00029-3. doi: 10.1016/j.tcm.2021.02.008. Epub ahead of print. PMID: 33675959. (SA, Editorial)1. journals2021
Junyan ShiShi J, Bird R, Schmeling MW, Hoofnagle AN. Using mass spectrometry to overcome the longstanding inaccuracy of a commercially-available clinical testosterone immunoassay. J Chromatogr B Analyt Technol Biomed Life Sci. 2021. Re-submitted after revision. IF: 3.2051. journals2021
Junyan ShiShi J, Lindo EG, Geoffrey BS, Young B, Michael R, Jefferson JA, Mehrotra R, Mathias PC, Hoofnagle AN. Calculating estimated glomerular filtration rate without the race correction factor: Observations at a large academic medical system. Clinica Chimica Acta. 2021; ONLINE AHEAD OF PRINT. IF: 2.6151. journals2021
Junyan ShiShi J, Xu Y. Epidemiology, diagnosis, and treatment of Fusarium infection. Chinese Journal of Mycology. 2009(2). Chinese1. journals2021
Kamilla Schlade-BartusiakChin HL, O'Neill K, Louie K, Brown L, Schlade-Bartusiak K, Eydoux P, Rupps R, Farahani A, Boerkoel CF, Jones SJM. An approach to rapid characterization of DMD copy number variants for prenatal risk assessment. Am J Med Genet A. 2021 Aug;185(8):2541-2545.1. journals2021
Kamilla Schlade-BartusiakPhillips EA, Caluseriu O, Schlade-Bartusiak K, Chernos J, McLeod DR, Thomas MA. Clinical and molecular characterization of an almost complete ring chromosome 4 in two sisters, with recurrence due to gonadal mosaicism. Clin Dysmorphol. 2021 Oct 1;30(4):173-176.1. journals2021
Katherine ChipperfieldLabrie A, Corr T, Berkowitz J, Roland K, Chipperfield K.  Comparison of in vivo outcome following transfusion of dynamic light scattering-screened versus unscreened platelets in hematologic malignancy: A randomized controlled trial.
Submitted to March 2021 Transfusion, AABB Press.
 
 
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Kerstin LocherMacDonald C., Desruisseaux C., Eckbo E., Li L, Locher K., Wong T., Grant J., Lavergne V., Schaeffer D., Hoang L., Charles M. bbott ID NOW„¢ COVID-19 Assay: Do Not Discard the Swab. Diagnostic Microbiology and Infectious Disease, under review
 
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Kevin BennewithFirmino N and Bennewith KL.  Germinal center hypoxia in tumor-draining lymph nodes negatively regulates humoral immune responses and affects the activation of tumor-infiltrating T cells.  Cancer Immunol Res 10(Suppl 1): P013, 2021.1. journals2021
Kevin BennewithLebovitz C, Wretham N, Osooly M, Milne K, Dash T, Thornton S, Tessier-Cloutier B, Sathiyaseelan P, Bortnik S, Go NE, Halvorsen EC, Cederberg RA, Chow N, Dos Santos N, Bennewith KL, Nelson BH, Bally MB, Lam WL and Gorski SM.  Loss of Parkinson€™s susceptibility gene LRRK2 promotes carcinogen-induced lung tumorigenesis.  Sci Rep 11(1): 2097, 2021. CA1. journals2021
Kevin BennewithPatel P, Vyravanathan S, Milne E, Bezjak A, Wouters BG, Bennewith K, Seuntjens J, Liu ZA, Harding SM, Liu F-F, Koritzinsky M, Koch CA. Strategic training in transdisciplinary radiation science for the 21st century (STARS21): 15-year evaluation of an innovative research training program. Int J Radiat Oncol Biol Phys 110(3): 656-66, 2021. CA1. journals2021
Kevin BennewithDecotret LR, Wadsworth BJ, Li LV, Lim CJ, Bennewith KL and Pallen CJ. Receptor-type protein tyrosine phosphatase alpha (PTPα) mediates MMP14 localization and facilitates triple-negative breast cancer cell invasion. Mol Biol Cell 32(7): 567-78, 2021. CA1. journals2021
Kevin BennewithWadsworth BJ, Decotret LR, Villamil C, Yapp D, Wilson D, Benard F, McKenzie M and Bennewith KL. Evaluation of 18F-EF5 for detection of hypoxia in localized adenocarcinoma of the prostate. Acta Oncol 11: 1-10, 2021. SA1. journals2021
Kevin BennewithFirmino NS, Cederberg RA, Lee C-M, Shi R, Wadsworth BJ, Franks SE, Thomas KN, Decotret LR and Bennewith KL. Germinal center hypoxia in tumor-draining lymph nodes negatively regulates tumor-induced humoral immune responses in mouse models of breast cancer. Oncoimmunology 10(1): 1959978, 2021. SA1. journals2021
Kevin BennewithWadsworth BJ, Lee C-M and Bennewith KL. Transiently hypoxic tumour cell turnover and radiation sensitivity in human tumour xenografts.  Br J Cancer (in press), 2021. [Subject of an invited Editorial]  SA1. journals2021
Kevin BennewithMelese* ES, Franks* SE, Cederberg RA, Harbourne BT, Shi R, Wadsworth BJ, Collier JL, Halvorsen EC, Luu J, Oh MH, Lam V, Krystal G, Hoover SB, Raffeld M, Simpson RM, Unni AM, Lam WL, Lam S, Abraham N, Bennewith^ KL and Lockwood^ WW. [*co-first authors; ^co-senior authors] Oncogene driven CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumour development. Oncoimmunology (in press), 2021. SA1. journals2021
Kevin BennewithWadsworth BJ, Lee C-M, Urban R, Hamilton SN and Bennewith KL. Angiotensin II receptor blockers modify the solid tumor microenvironment and improve radiation therapy response. Clin Cancer Res 27(8; Suppl S): PR-001, 2021.1. journals2021
Kevin BennewithLee C-M, Wadsworth BJ and Bennewith KL. Changes in cancer-associated fibroblast subsets following angiotensin II receptor blocker (ARB) treatment reduces transient hypoxia and radiation resistance. Clin Cancer Res 27(8; Suppl S): PO-034, 2021.1. journals2021
Kevin BennewithDecotret LR, Shi R and Bennewith KL. Targeting focal adhesions to limit radiation-induced glioblastoma cell invasion. Clin Cancer Res 27(8; Suppl S): PO-053, 2021.1. journals2021
Kevin BennewithCederberg RA and Bennewith KL.  Eosinophils inhibit breast cancer pulmonary metastatic colonization and directly kill tumor cells via degranulation.  J Immunol 206(Suppl 1): 101.07, 2021.1. journals2021
Kevin BennewithMelese ES, Franks SE, Cederberg R, Seo JH, Lam W, Bennewith KL, Lockwood W and Abraham N.  The role of CD4+ tissue resident memory cells in oncogene driven lung adenocarcinoma.  J Immunol 206(Suppl 1): 57.22, 2021.1. journals2021
Kirsten FlemingDeCoste RC, Carter MD, Pasternak S, Fleming KE, Gaston D, Legge A, Ly TY, Walsh NM. Relationship between p63 and p53 expression in Merkel cell carcinoma and corresponding abnormalities in and TP53: a study and a proposal. Hum Pathol. 2021; 117: 31-41.1. journals2021
Krista MarconMcGinnis E, Guo RJ, Marcon K, Berry B, Coupland R, Meneghetti V, Morrison D, Onell R, Steele L, Trudeau J, Wong M, Shih AW. €œAdaptations of transfusion systems to the COVID-19 pandemic in British Columbia, Canada: early experiences of a large tertiary care center and survey of provincial activities€. Transfusion (2021).1. journals2021
Krista MarconDehghan N, Marcon K, Sedic T, Dutz JP, Beck DB, Chen LYC €œVacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome: fevers, myalgia, arthralgia, auricular chondritis, and erythema nodosum.€ The Lancet. Volume 398, Issue 10300 (2021): 621.1. journals2021
Krista MarconAl Moosawi, M., Marcon, K. €œBone marrow involvement by CD1a-negative langerhans cell histiocytosis with associated hemophagocytosis€. Int J Hematol (2021).1. journals2021
Kristine RolandEric McGinnis, Geoffrey Chan, Monika Hudoba, Todd Markin, Jim Yakimec, Kristine Roland.  Malaria screening using front-line loop-mediated isothermal amplification (LAMP): fourteen-month experience in a non-endemic regional hub-and-spoke laboratory setting.  American Journal of Clinical Pathology. 2021 Apr 26;155(5):690-6971. journals2021
Kristine RolandAnn Tran, Monika Hudoba, Todd Markin, Kristine Roland. Sustainable laboratory-driven method to decrease repeat, same-day WBC differentials at a tertiary care centre.  American Journal of Clinical Pathology. 2021 (Oct 7).1. journals2021
Linda HoangNasreen S, Wang J, Kwong JC, Crowcroft NS, Sadarangani M, Wilson SE, McGeer A, Kellner JD, Quach C, Morris SK, Sander B, Kus JV, Naus M, Hoang L, Rudzicz F, Fadel S, Marra F. Population-based incidence of invasive pneumococcal disease in children and adults in Ontario and British Columbia, 2002-2018: A Canadian Immunization Research Network (CIRN) study. Vaccine. 2021 Dec 20;39(52):7545-7553. PMID: 348100011. journals2021
Linda HoangEckbo EJ, Wong T, Bharat A, Cameron-Lane M, Hoang L, Dawar M, Charles M. First reported outbreak of the emerging pathogen Candida auris in Canada. Am J Infect Control. 2021 Jan 21;49(6):804-807. PMID: 334859221. journals2021
Linda HoangGoldfarb DM, Tilley P, Al-Rawahi GN, Srigley JA, Ford G, Pedersen H, Pabbi A, Hannam-Clark S, Charles M, Dittrick M, Gadkar VJ, Pernica JM, Hoang LMN. Self-Collected Saline Gargle Samples as an Alternative to Health Care Worker-Collected Nasopharyngeal Swabs for COVID-19 Diagnosis in Outpatients. J Clin Microbiol. 2021 Mar 19;59(4):e02427-20. PMID: 335146271. journals2021
Linda HoangBoyd E, Trmcic A, Taylor M, Shyng S, Hasselback P, Man S, Tchao C, Stone J, Janz L, Hoang L, Galanis E. Escherichia coli O121 outbreak associated with raw milk Gouda-like cheese in British Columbia, Canada, 2018. Can Commun Dis Rep. 2021 Jan 29;47(2):11-16. PMID: 337466161. journals2021
Linda HoangBoyd DA, Mataseje LF, Dingle T, Hoang L, Lefebvre B, McGeer A, Melano RG, Stuart I, Walkty A, Wilmer A, Mulvey MR. Emergence of Morganellaceae Harboring blaIMP-27 Metalloenzyme in Canada. mSphere. 2021 May 19;6(3):e00048-21. PMID: 340116801. journals2021
Linda HoangTauh T, Lee SM, Meyler P, Mozel M, McLennan M, Hoang LMN. Diagnostic performance and clinical application of preoperative COVID-19 bedside testing with ID NOW„¢. Can J Anaesth. 2021 Oct;68(10):1569-1571. PMID: 340214771. journals2021
Linda HoangSkowronski DM, Setayeshgar S, Zou M, Prystajecky N, Tyson JR, Galanis E, Naus M, Patrick DM, Sbihi H, El Adam S, Henry B, Hoang LMN, Sadarangani M, Jassem AN, Krajden M. Single-dose mRNA vaccine effectiveness against SARS-CoV-2, including Alpha and Gamma variants: a test-negative design in adults 70 years and older in British Columbia, Canada. Clin Infect Dis. 2021 Jul 9:ciab616. PMID: 342447231. journals2021
Linda HoangTauh T, Lee SM, Meyler P, Mozel M, McLennan M, Hoang LMN. Correction to: Diagnostic performance and clinical application of preoperative COVID-19 bedside testing with ID NOW„¢. Can J Anaesth. 2021 Nov;68(11):1729. PMID: 342687181. journals2021
Linda HoangHogan CA, Jassem AN, Sbihi H, Joffres Y, Tyson JR, Noftall K, Taylor M, Lee T, Fjell C, Wilmer A, Galbraith J, Romney MG, Henry B, Krajden M, Galanis E, Prystajecky N, Hoang LMN. Rapid Increase in SARS-CoV-2 P.1 Lineage Leading to Codominance with B.1.1.7 Lineage, British Columbia, Canada, January-April 2021. Emerg Infect Dis. 2021 Nov;27(11):2802-2809. PMID: 343883581. journals2021
Linda HoangAhmed-Bentley J, Roman S, Mirzanejad Y, Fraser E, Hoang L, Young EJ, Morshed M, Deans G. Laboratory Exposures from an Unsuspected Case of Human Infection with Brucella canis. Emerg Infect Dis. 2021 Sep;27(9):2489-2491. PMID: 344241691. journals2021
Linda HoangCox GW, Parmley EJ, Avery BP, Irwin RJ, Reid-Smith RJ, Deckert AE, Finley RL, Daignault D, Alexander DC, Allen V, El Bailey S, Bekal S, Chui L, German GJ, Haldane D, Hoang L, Minion J, Zahariadis G, Mulvey MR, Bharat A. A one health genomic investigation of gentamicin resistance in Salmonella from human and chicken sources in Canada, 2014-2017. Antimicrob Agents Chemother. 2021 Sep 27:AAC0096621. PMID: 345706421. journals2021
Linda HoangDemczuk W, Martin I, Griffith A, Lefebvre B, McGeer A, Tyrrell GJ, Zhanel GG, Kus JV, Hoang L, Minion J, Van Caeseele P, Gad RR, Haldane D, Zahariadis G, Mead K, Steven L, Strudwick L, Mulvey MR. Linear regression equations to predict β-lactam, macrolide, lincosamide and fluoroquinolone minimum inhibitory concentrations from molecular antimicrobial resistance determinants in Streptococcus pneumoniae. Antimicrob Agents Chemother. 2021 Oct 18:AAC0137021. PMID: 346621971. journals2021
Linda HoangTeman SJ, Gaydos JK, Norman SA, Huggins JL, Lambourn DM, Calambokidis J, Ford JKB, Hanson MB, Haulena M, Zabek E, Cottrell P, Hoang L, Morshed M, Garner MM, Raverty S. Epizootiology of a Cryptococcus gattii outbreak in porpoises and dolphins from the Salish Sea. Dis Aquat Organ. 2021 Oct 21;146:129-143. PMID: 346722631. journals2021
Linda HoangKuchinski KS, Nguyen J, Lee TD, Hickman R, Jassem AN, Hoang LMN, Prystajecky NA, Tyson JR. Mutations in emerging variant of concern lineages disrupt genomic sequencing of SARS-CoV-2 clinical specimens. Int J Infect Dis. 2021 Oct 29:S1201-9712(21)00838-9. PMID: 347572011. journals2021
Linda HoangKinshella MW, Tilley P, Al-Rawahi GN, Srigley JA, Kayda I, Canes M, McLennan M, Bone JN, Dittrick M, Gadkar VJ, Hoang LMN, Goldfarb DM. Evaluation of observed and unobserved self-collection of saline gargle samples for the detection of SARS-CoV-2 in outpatients. Diagn Microbiol Infect Dis. 2021 Oct 2;102(2):115566. PMID: 347811641. journals2021
Linda HoangHogan CA, Sbihi H, Jassem A, Prystajecky N, Tyson JR, Lee TD, Tsang F, Ng C, Janz L, Romney MG, Hoang L. Optimizing SARS-CoV-2 Variant of Concern Screening: Experience from British Columbia, Canada, Early 2021. medRxiv. 2021.1. journals2021
Linda HoangSkowronski DM, Setayeshgar S, Zou M, Prystajecky N, Tyson JR, Sbihi H, Fjell CD, Galanis E, Naus M, Patrick DM, El Adam S, Ahmed M, Kim S, Henry B, Hoang LMN, Sadarangani M, Jassem AN, Krajden M. Comparative single-dose mRNA and ChAdOx1 vaccine effectiveness against SARS-CoV-2, including early variants of concern: a test-negative design, British Columbia, Canada. J Infect Dis. 2021.1. journals2021
Linda HoangSkowronski DM, Setayeshgar S, Febriani Y, Ouakki M, Zou M, Talbot D, Prystajecky N, Tyson JR, Gilca R, Brousseau N, Deceuninck G, Galanis E, Fjell CD, Sbihi H, Fortin E, Barkati S, Sauvageau C, Naus M, Patrick DM, Henry B, Hoang LMN, De Wals P, Garenc C, Carignan A, Drolet M, Sadarangani M, Brisson M, Krajden M and De Serres G. Two-dose SARS-CoV-2 vaccine effectiveness with mixed schedules and extended dosing intervals: test-negative design studies from British Columbia and Quebec, Canada. medRxiv. 2021.1. journals2021
Linda HoangLin D, Sutherland D, Aninta S, Nip KM, Li C, Warren RL, Helbing C, Hoang L, Birol I. rAMPage: Rapid AMP Annotation and Gene Estimation. rAMPage Github Release. 2021.1. journals2021
Lindsay BrownRebecca Ronsley, Christopher Dunham , Stephen Yip, Lindsay Brown, Jeffrey A Zuccato, Shirin Karimi, Gelareh Zadeh, Karen Goddard, Ash Singhal, Juliette Hukin, Sylvia Cheng. A case series of pediatric survivors of anaplastic pleomorphic xanthoastrocytoma. Neurooncol Adv. 2021 Jan 30;3(1):vdaa176.1. journals2021
Lisa Li Locher K, Velapatino B, Caza M, Li L, Porter C, Charles M. Approach to assessment of new swabs and viral transport media for SARS-CoV-2 testing. J Clin Microbiol. 2021 Apr 20;59(5):e01562-20.1. journals2021
Lucy PerroneMcNabb SJN, Magowe M, Shaw N, Berrian AM, Wilkes M, Shaikh A, Gachuno O, Perrone LA, Murray BL, Berman E, Hansoti B. Delivering Modern Global Health Learning Requires New Obligations and Approaches. Ann Glob Health. 2021 Jul 12;87(1):68. doi: 10.5334/aogh.3261. PMID: 34307071; PMCID: PMC8284535.1. journals2021
Lucy PerroneKirk M, Assoa PH, Iiams-Hauser C, Kouabenan YR, Antilla J, Steele-Lane C, Rossum G, Komena P, Ngatchou PS, Abiola N, Kouakou A, Pongathie A, Koffi JB, Adje C, Perrone LA. Adaptation of an electronic dashboard to monitor HIV viral load testing in Côte d'Ivoire. Afr J Lab Med. 2021 May 17;10(1):1284. doi: 10.4102/ajlm.v10i1.1284. PMID: 34192117; PMCID: PMC8182557.1. journals2021
Lucy PerroneGopolang F, Zulu-Mwamba F, Nsama D, Kruuner A, Nsofwa D, Kasvosve I, Gomo R, Motlhabane T, Chohan B, Soge O, Osterhage D, Campbell N, Noble M, Downer A, Flandin JF, Nartker A, Koehn C, Nonde LK, Shibemba A, Ndongmo CB, Steinau M, Perrone LA. Improving laboratory quality and capacity through leadership and management training: Lessons from Zambia 2016-2018. Afr J Lab Med. 2021 Apr 30;10(1):1225. doi: 10.4102/ajlm.v10i1.1225. PMID: 34007816; PMCID: PMC8111616.1. journals2021
Lucy PerroneLane, J., Means, A., Bardosh, K., Shapoval, A., Vio, F., Anderson, C., Cushnie, A., Forster, N., Ledikwe, J., O€™Malley, G., Mawandia, S., Parvez, A., Perrone, L.A., Mudender, F.. Comparing COVID-19 Physical Distancing Policies: Results from a Physical Distancing Intensity Coding Framework for Botswana, India, Jamaica, Mozambique, Namibia, Ukraine, and the United States. In press at the Journal of Globalisation and Health. Pre-print published online on February 12, 2021 at doi: https://doi.org/10.1101/2021.02.09.212514331.     1. journals2021
Marc RomneyLi L, Lowe C, Ritchie G, Stefanovic A, Champagne S, Romney M, Leung V, Matic N. SARS-CoV-2 molecular testing for the diagnosis of COVID-19: One test does not fit all. Journal of Medical Virology 2021;93(2):712-713.1. journals2021
Marc RomneyMatic N, Lawson T, Ritchie G, Stefanovic A, Leung V, Champagne S, Romney MG, Lowe CF. Automated molecular testing of saliva for SARS-CoV-2 detection. Diagnostic Microbiology and Infectious Disease 2021;doi:10.1016/j.diagmicrobio. 2021.115324.1. journals2021
Marc RomneyCojocaru R, Yaseen I, Unrau PJ, Lowe CF, Ritchie G, Romney MG, Sin DD, Gill S, Slyadnev M. Validation of a Rapid and Low Resource, Real Time Microchip PCR Kit for SARS-CoV-2 Detection. Journal of Molecular Diagnostics [In Press] 2021; doi:10.1016/j.jmoldx.2021.02.009.1. journals2021
Marc RomneyMatic N, Stefanovic A, Leung V, Lawson T, Ritchie G, Li L, Champagne S, Romney MG, Lowe CF. Practical challenges to the clinical implementation of saliva for SARS-CoV-2 detection.  European Journal of Clinical Microbiology and Infectious Diseases 2021;40(2):447-450.1. journals2021
Marc RomneyMatic N, Lowe CF, Ritchie G, Stefanovic A, Lawson T, Jang W, Young M, Dong W, Brumme ZL, Brumme CJ, Leung V, Romney MG. Rapid detection of SARS-CoV-2 variants of concern identifying a cluster of B.1.1.28/P.1 variant in British Columbia, Canada. Emerging Infectious Diseases [In Press] 2021 June;27(6).1. journals2021
Marcel BallyLebovitz C, Wretham N, Osooly M, Milne K, Dash T, Thornton S, Tessier-Cloutier B, Sathiyaseelan P, Bortnik S, Go NE, Halvorsen E, Cederberg RA, Chow N, Dos Santos N, Bennewith KL, Nelson BH, Bally MB, Lam WL, Goski SM. Loss of Parkinson€™s susceptibility gene LRRK2 promotes carcinogen-induced lung tumorigenesis. Scientific Reports. 2021 Jan 22;11(1):1-4. CA1. journals2021
Marcel BallyChen KTJ, Militao GGC, Anantha M, Witzigmann D, Leung AWY, Bally MB. Development and characterization of a novel flavopiridol formulation for treatment of acute myeloid leukemia. J Control Release. 2021 May 10;333:246-257. SA1. journals2021
Marcel BallyKalra J, Baker J, Song J, Kyle A, Minchinton A, Bally M. Inter-Metastatic Heterogeneity of Tumor Marker Expression and Microenvironment Architecture in a Preclinical Cancer Model. International Journal of Molecular Sciences. 2021 Jan;22(12):6336. SA1. journals2021
Marcel Ballyvan der Meel R, Chen S, Zaifman J, Kulkarni JA, Zhang XRS, Tam YK, Bally MB, Schiffelers RM, Ciufolini MA, Cullis PR, Tam YYC. Modular Lipid Nanoparticle Platform Technology for siRNA and Lipophilic Prodrug Delivery.Small. 2021 Sep;17(37):e2103025. CA1. journals2021
Marcel BallyPerkins M, Schuetz M, Unda F, Chen TJ, Bally MB, Kulkarni J, Mansfield SD, Samuels L. Monolignol export by diffusion down a polymerization-induced concentration gradient. Accepted to Nature Plants, Jan 2022.1. journals2021
Marianne SadarObst JK, Mawji NR, Teskey SJL, Wang J, Sadar MD. Differential gene expression profiles between N-terminal domain and ligand-binding domain inhibitors of androgen receptor reveal ralaniten induction of metallothionein by a mechanism dependent on MTF1. Cancers. Published in January 20221. journals2021
Marianne SadarYan L, Banuelos CA, Mawji NR, Patrick BO, Sadar MD* Andersen RJ. Structure-Activity Relationships for the Marine Natural Product Sintokamides - Androgen Receptor N-Terminus Antagonists of Interest for Treatment of Metastatic Castration Resistant Prostate Cancer. J. Natural Products.2021 Mar 26;84(3):797-813. doi: 10.1021/acs.jnatprod.0c00921. PMID: 33124806 (Co-SA) *Co-corresponding author1. journals2021
Marianne SadarTien AH  and Sadar MD. Cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with ralaniten analogues for the treatment of androgen receptor-positive prostate and breast cancers. Mol Cancer Ther. 2021 Nov 23:molcanther.0411.2021. doi: 10.1158/1535-7163.MCT-21-0411. Epub ahead of print. PMID: 34815359. (CA, SA)1. journals2021
Marianne SadarLeung JK, Imamura Y, Kato M, Wang J, Mawji NR, Sadar MD. Pin1 inhibition improves the efficacy of ralaniten compounds that bind to the N-terminal domain of androgen receptor. Commun Biol. 2021 Mar 22;4(1):381. doi: 10.1038/s42003-021-01927-3. PMID: 33753863. (CA)1. journals2021
Marianne SadarLeung JK, Tam T, Wang J, Sadar MD. Isolation and characterization of castration-resistant prostate cancer LNCaP95 clones. Human Cell. 2021 Jan;34(1):211-218.  doi: 10.1007/s13577-020-00435-6. Epub 2020 Sep 20. PMID: 32954481 (CA)1. journals2021
Mark ScottYang X, Toyofuku WM, Scott MD. Differential Leukocyte MicroRNA Responses Following Pan T Cell, Allorecognition and Allosecretome-Based Therapeutic Activation. Arch Immunol Ther Exp (Warsz). 2021 Oct 22;69(1):30. doi: 10.1007/s00005-021-00634-5. PMID: 34677693; PMCID: PMC8536625.1. journals2021
Marthe CharlesSekirov I, Barakauskas VE, Simons J, Cook D, Bates B, Burns L, Masud S, Charles M, McLennan M, Mak A, Chahil N, Vijh R, Hayden A, Goldfarb D, Levett PN, Krajden M, Morshed M. SARS-CoV-2 serology: Validation of high-throughput chemiluminescent immunoassay (CLIA) platforms and a field study in British Columbia. J Clin Virol. 2021 Jul 16;142:104914. doi: 10.1016/j.jcv.2021.104914. Epub ahead of print. PMID: 34304088; PMCID: PMC8282439.1. journals2021
Marthe CharlesEckbo EJ, Charles M, Wolber R, Yu G. Relapsing fever in a traveller returning from Senegal. CMAJ. 2021 Feb 22;193(8):E285-E288. doi: 10.1503/cmaj.201644. PMID: 33619068; PMCID: PMC8034351.1. journals2021
Marthe CharlesGoldfarb DM, Tilley P, Al-Rawahi GN, Srigley JA, Ford G, Pedersen H, Pabbi A, Hannam-Clark S, Charles M, Dittrick M, Gadkar VJ, Pernica JM, Hoang LMN. Self-Collected Saline Gargle Samples as an Alternative to Health Care Worker-Collected Nasopharyngeal Swabs for COVID-19 Diagnosis in Outpatients. J Clin Microbiol. 2021 Mar 19;59(4):e02427-20. doi: 10.1128/JCM.02427-20. PMID: 33514627; PMCID: PMC8092743.1. journals2021
Marthe CharlesEckbo EJ, Wong T, Bharat A, Cameron-Lane M, Hoang L, Dawar M, Charles M. First reported outbreak of the emerging pathogen Candida auris in Canada. Am J Infect Control. 2021 Jun;49(6):804-807. doi: 10.1016/j.ajic.2021.01.013. Epub 2021 Jan 21. PMID: 33485922.1. journals2021
Marthe CharlesLocher K, Velapatino B, Caza M, Li L, Porter C, Charles M. Approach to Assessment of New Swabs and Viral Transport Media for SARS-CoV-2 Testing. J Clin Microbiol. 2021 Apr 20;59(5):e01562-20. doi: 10.1128/JCM.01562-20. PMID: 33139423; PMCID: PMC8091853.1. journals2021
Matthew Tak Sheng YanShopsowitz K, Lim C, Shih A, Fishbane N, Berry B, Bigham M, Petraszko T, Trudeau J, Wyatt M, Yan M, Morrison D. Impacts of COVID-19 and elective surgery cancellations on platelet supply and utilization in the Canadian province of British Colubmia. Vox Sanguinis; 2021. Published online https://doi.org/10.1111/vox.13180. CA1. journals2021
Matthew Tak Sheng YanBegin P, Callum J, Jamula E, Cook R, Heddle N, Tinmouth A, Zeller M, Beaudoin-Bussieres G, Amorim L, Bazin R, Loftsgard K, Carl R, Chasse M, Cushing M, Daneman N, Devine D, Dumaresq J, Fergusson D, Gabe C, Glesby M, Li N, Liu Y, McGeer A, Robitaille N, Sachais B, Scales D, Schwartz L, Shehata N, Turegon A, Heidi W, Zarychanski R, Finzi A, CONCOR-1 Study Group*, Arnold D. Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial. Nature Medicine 2021; published online. *Site principle investigator & co-author as part of the CONCOR-1 Study Group1. journals2021
Mehdi AgoumiKaracabeyli D, Abu-Abed S, Agoumi M, Huang K. Myeloperoxidase positivity€‚in giant cell arteritis presenting with fever of unknown origin. Rheumatology (Oxford). 2021 Feb 1;60(2):e53-e55. doi: 10.1093/rheumatology/keaa442. PMID: 32885247.1. journals2021
Mei Lin Z. BissonnetteNicholl DDM, Whitelaw JP, Weir RV, Bissonnette MLZ, Gill JS, Landsberg DN. Case Report: Absence of Clinically Significant Recurrent Diabetic Kidney Disease on Postmortem Biopsy 32 Years After Kidney Transplantation for Type 1 Diabetes. Transplant Direct. 2021;7(12):e790.1. journals2021
Mei Lin Z. BissonnetteShashiprakash AK, Lutnick B, Ginley B, Govind D, Lucarelli N, Jen KY, Rosenberg AZ, Urisman A, Walavalkar V, Zuckerman JE, Delsante M, Bissonnette MLZ, Tomaszewski JE, Manthey D, Sarder P. A Distributed System Improves Inter-Observer and AI Concordance in Annotating Interstitial Fibrosis and Tubular Atrophy. Proc SPIE Int Soc Opt Eng. 2021;11603:116030V.1. journals2021
Mei Lin Z. BissonnetteAndeen NK, Abdulameer S, Charu V, Zuckerman JE, Troxell M, Kambham N, Alpers CE, Najafian B, Nicosia RF, Smith KD, Kung VL, Avasare RS, Vallurupalli A, Jefferson JA, Hecox D, Swetnam L, Yamashita M, Lin M, Bissonnette ML, Akilesh S, Hou J. A Diverse Spectrum of Immune Complex- and Complement-Mediated Kidney Diseases Is Associated With Mantle Cell Lymphoma. Kidney Int Rep. 2021;7(3):568-579.1. journals2021
Mel KrajdenValerio H, Alavi M, Law M, McManus H, Tillakeratne S, Bajis S, Martinello M, Matthews GV, Amin J, Janjua NZ, Krajden M, George J, Degenhardt L, Grebely J, Dore GJ. Opportunities to enhance linkage to hepatitis C care among hospitalised people with recent drug dependence in New South Wales, Australia: A population-based linkage study. Clin Infect Dis. 2021 Jun 9:ciab526. doi: 10.1093/cid/ciab526. Online ahead of print.1. journals2021
Mel KrajdenJeong D, Karim ME, Wong S, Wilton J, Butt ZA, Binka M, Adu PA, Bartlett S, Pearce M, Clementi E, Yu A, Alvarez M, Samji H, Velásquez García HA, Abdia Y, Krajden M, Janjua NZ. Impact of HCV infection and ethnicity on incident type 2 diabetes: findings from a large population-based cohort in British Columbia. BMJ Open Diabetes Res Care. 2021 Jun;9(1):e002145. doi: 10.1136/bmjdrc-2021-002145.1. journals2021
Mel KrajdenStrang THR, Gottschlich A, Cook DA, Smith LW, Gondara L, Franco EL, Niekerk DJV, Ogilvie GS, Krajden M. Long-term cervical precancer outcomes after a negative DNA- or RNA-based human papillomavirus test result. Am J Obstet Gynecol. 2021 May 31:S0002-9378(21)00606-2. doi: 10.1016/j.ajog.2021.05.038. Online ahead of print.1. journals2021
Mel KrajdenJanjua NZ, Wong S, Abdia Y, Jeong D, Buller-Tylor T, Adu P, Samji H, Wilton J, Pearce M, Butt ZA, Yu A, Binka M, Bartlett S, Alvarez M, Krajden M. Impact of direct-acting antivirals for HCV on mortality in a large population-based cohort study. J Hepatol. 2021 Jun 4:S0168-8278(21)00401-3. doi: 10.1016/j.jhep.2021.05.028. Online ahead of print.1. journals2021
Mel KrajdenFang Fang Li, Aaron Liu, Ebrima Gibbs, Guadalein Tanunliong, Ana Citlali Marquez, Soren Gantt, Hans Frykman, Mel Krajden, Muhammed Morshed, Natalie A. Prystajecky, Neil Cashman, Inna Sekirov, Dr. Agatha N. Jassem. (2021). A novel multiplex electrochemiluminescent immunoassay for detection and quantification of anti-SARS-CoV-2 IgG and anti-seasonal endemic human coronavirus IgG. Journal of Clinical Virology, 2021, (105050) ISSN 1386-6532. https://doi.org/10.1016/j.jcv.2021.105050.(https://www.sciencedirect.com/science/article/pii/S1386653221003176) 1. journals2021
Mel KrajdenValerio H, Alavi M, Law M, Tillakeratne S, Amin J, Janjua N, Krajden M, George J, Matthews GV, Hajarizadeh B, Degenhardt L, Grebely J, Dore GJ. High hepatitis C treatment uptake among people with recent drug dependence in New South Wales, Australia. J Hepatol. 2021 Feb;74(2):293-302. doi: 10.1016/j.jhep.2020.08.038. Epub 2020 Sep 12.1. journals2021
Mel KrajdenGottschlich A, van Niekerk D, Smith LW, Gondara L, Melnikow J, Cook DA, Lee M, Stuart G, Martin RE, Peacock S, Franco EL, Coldman A, Krajden M, Ogilvie G. Assessing 10-Year Safety of a Single Negative HPV Test for Cervical Cancer Screening: Evidence from FOCAL-DECADE Cohort. Cancer Epidemiol Biomarkers Prev. 2021 Jan;30(1):22-29. doi: 10.1158/1055-9965.EPI-20-1177. Epub 2020 Oct 20.1. journals2021
Mel KrajdenVijh R, Ghafari C, Hayden A, Schwandt M, Sekirov I, Morshed M, Levett P, Krajden M, Boraston S, Daly P, Lysyshyn M, Harding J, McLennan M, Chahil N, Mak A, McKee G. Serological survey following SARS-COV-2 outbreaks at long-term care facilities in metro Vancouver, British Columbia: Implications for outbreak management and infection control policies. Am J Infect Control. 2021 May;49(5):649-652. doi: 10.1016/j.ajic.2020.10.009. Epub 2020 Oct 18.1. journals2021
Mel KrajdenAdu PA, Rossi C, Binka M, Wong S, Wilton J, Wong J, Butt ZA, Bartlett S, Jeong D, Pearce M, Darvishian M, Yu A, Alvarez M, Velásquez García HA, Krajden M, Janjua NZ. HCV reinfection rates after cure or spontaneous clearance among HIV-infected and uninfected men who have sex with men. Liver Int. 2021 Mar;41(3):482-493. doi: 10.1111/liv.14762. Epub 2020 Dec 22.1. journals2021
Mel KrajdenDonken R, van Niekerk D, Hamm J, Spinelli JJ, Smith L, Sadarangani M, Albert A, Money D, Dobson S, Miller D, Lee M, Mitchell-Foster S, Krajden M, Naus M, Ogilvie G. Declining rates of cervical intraepithelial neoplasia in British Columbia, Canada: An ecological analysis on the effects of the school-based human papillomavirus vaccination program. Int J Cancer. 2021 Jul 1;149(1):191-199. doi: 10.1002/ijc.33513. Epub 2021 Feb 26.1. journals2021
Mel KrajdenAntuori A, Montoya V, Piñeyro D, Sumoy L, Joy J, Krajden M, González-Gómez S, Folch C, Casabona J, Matas L, Colom J, Saludes V, Martró E; HepCdetect II Study Group. Characterization of acute HCV infection and transmission networks in people who currently inject drugs in Catalonia: usefulness of dried blood spots. Hepatology. 2021 Feb 20. doi: 10.1002/hep.31757. Online ahead of print.1. journals2021
Mel KrajdenDarvishian M, Butt ZA, Wong S, Yoshida EM, Khinda J, Otterstatter M, Yu A, Binka M, Rossi C, McKee G, Pearce M, Alvarez M, Wong J, Cook D, Grennan T, Buxton J, Tyndall M, Woods R, Krajden M, Bhatti P, Janjua NZ. Elevated risk of colorectal, liver, and pancreatic cancers among HCV, HBV and/or HIV (co)infected individuals in a population based cohort in Canada. Ther Adv Med Oncol. 2021 Feb 11;13:1758835921992987. doi: 10.1177/1758835921992987. eCollection 2021.1. journals2021
Mel KrajdenLiu M, Arora RK, Krajden M. Rapid antigen tests for SARS-CoV-2. CMAJ. 2021 Mar 29;193(13):E447. doi: 10.1503/cmaj.202827. Epub 2021 Mar 2.1. journals2021
Mel KrajdenMorshed M, Sekirov I, McLennan M, Levett PN, Chahil N, Mak A, Carruthers E, Pidduck T, Kustra J, Laley J, Lee MK, Chu K, Burgess F, Vijh R, Willis L, Wada R, Blancaflor R, Boraston S, Hayden A, Krajden M. Comparative Analysis of Capillary vs Venous Blood for Serologic Detection of SARS-CoV-2 Antibodies by RPOC Lateral Flow Tests. Open Forum Infect Dis. 2021 Jan 28;8(3):ofab043. doi: 10.1093/ofid/ofab043. eCollection 2021 Mar.1. journals2021
Mel KrajdenBinka M, Butt ZA, McKee G, Darvishian M, Cook D, Wong S, Yu A, Alvarez M, Samji H, Wong J, Krajden M, Janjua NZ. Differences in risk factors for hepatitis B, hepatitis C, and human immunodeficiency virus infection by ethnicity: A large population-based cohort study in British Columbia, Canada. Int J Infect Dis. 2021 Mar 23;106:246-253. doi: 10.1016/j.ijid.2021.03.061. Online ahead of print.1. journals2021
Mel KrajdenSkowronski DM, Setayeshgar S, Zou M, Prystajecky N, Tyson JR, Galanis E, Naus M, Patrick DM, Sbihi H, El Adam S, Henry B, Hoang LMN, Sadarangani M, Jassem AN, Krajden M. Single-dose mRNA vaccine effectiveness against SARS-CoV-2, including Alpha and Gamma variants: a test-negative design in adults 70 years and older in British Columbia, Canada. Clin Infect Dis. 2021 Jul 9:ciab616. doi: 10.1093/cid/ciab616. Online ahead of print.1. journals2021
Mel KrajdenCromwell I, Smith LW, van der Hoek K, Hedden L, Coldman AJ, Cook D, Franco EL, Krajden M, Martin R, Lee MH, Stuart G, van Niekerk D, Ogilvie G, Peacock S. Cost-effectiveness analysis of primary human papillomavirus testing in cervical cancer screening: Results from the HPV FOCAL Trial. Cancer Med. 2021 May;10(9):2996-3003. doi: 10.1002/cam4.3864. Epub 2021 Apr 2.1. journals2021
Mel KrajdenNikiforuk AM, Kuchinski KS, Twa DDW, Lukac CD, Sbihi H, Basham CA, Steidl C, Prystajecky NA, Jassem AN, Krajden M, Patrick DM, Sekirov I. The contrasting role of nasopharyngeal angiotensin converting enzyme 2 (ACE2) transcription in SARS-CoV-2 infection: A cross-sectional study of people tested for COVID-19 in British Columbia, Canada. EBioMedicine. 2021 Apr;66:103316. doi: 10.1016/j.ebiom.2021.103316. Epub 2021 Apr 2.1. journals2021
Mel KrajdenSekirov I, Barakauskas VE, Simons J, Cook D, Bates B, Burns L, Masud S, Charles M, McLennan M, Mak A, Chahil N, Vijh R, Hayden A, Goldfarb D, Levett PN, Krajden M, Morshed M. SARS-CoV-2 serology: Validation of high-throughput chemiluminescent immunoassay (CLIA) platforms and a field study in British Columbia. J Clin Virol. 2021 Jul 16;142:104914. doi: 10.1016/j.jcv.2021.104914. Online ahead of print.1. journals2021
Mel KrajdenBartlett SR, Wong S, Yu A, Pearce M, MacIsaac J, Nouch S, Adu P, Wilton J, Samji H, Clementi E, Velasquez H, Jeong D, Binka M, Alvarez M, Wong J, Buxton J, Krajden M, Janjua NZ. The impact of current opioid agonist therapy on hepatitis C virus treatment initiation among people who use drugs from in the DAA era: A population-based study. Clin Infect Dis. 2021 Jun 14:ciab546. doi: 10.1093/cid/ciab546. Online ahead of print.1. journals2021
Mel KrajdenLitwin C, Smith L, Donken R, Krajden M, van Niekerk D, Naus M, Cook D, Albert A, Ogilvie G. High-risk HPV prevalence among women undergoing cervical cancer screening: Findings a decade after HPV vaccine implementation in British Columbia, Canada. Vaccine. 2021 Jul 31:S0264-410X(21)00868-9. doi: 10.1016/j.vaccine.2021.07.009. Online ahead of print.1. journals2021
Mel KrajdenLevett PN, Cheung B, Kustra J, Pidduck T, Mak A, Tsang F, Petric M, Krajden M. Evaluation of a high volume antigen test for detection of SARS-CoV-2. J Clin Virol. 2021 Aug 2;142:104938. doi: 10.1016/j.jcv.2021.104938. Online ahead of print.1. journals2021
Mel KrajdenMcClymont, E., Elwood, C., Sekirov, I., Morshed, M., Levett, P., Liu, A., Jassem, A., Sbihi, H., Ogilvie, G., Krajden, M., & Money, D. (2021). Population SARS-CoV-2 Seroprevalence Using Antenatal Serum Samples in British Columbia, Canada. Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 43(11), 1242€“1243. https://doi.org/10.1016/j.jogc.2021.06.0011. journals2021
Mel KrajdenHogan, C. A., Jassem, A. N., Sbihi, H., Joffres, Y., Tyson, J. R., Noftall, K., Taylor, M., Lee, T., Fjell, C., Wilmer, A., Galbraith, J., Romney, M. G., Henry, B., Krajden, M., Galanis, E., Prystajecky, N., & Hoang, L. (2021). Rapid Increase in SARS-CoV-2 P.1 Lineage Leading to Codominance with B.1.1.7 Lineage, British Columbia, Canada, January-April 2021. Emerging infectious diseases, 27(11), 2802€“2809. https://doi.org/10.3201/eid2711.2111901. journals2021
Mel KrajdenHaile, S., Nikiforuk, A. M., Pandoh, P. K., Twa, D., Smailus, D. E., Nguyen, J., Pleasance, S., Wong, A., Zhao, Y., Eisler, D., Moksa, M., Cao, Q., Wong, M., Su, E., Krzywinski, M., Nelson, J., Mungall, A. J., Tsang, F., Prentice, L. M., Jassem, A., €¦ Hirst, M. (2021). Optimization of magnetic bead-based nucleic acid extraction for SARS-CoV-2 testing using readily available reagents. Journal of virological methods, 299, 114339. Advance online publication. https://doi.org/10.1016/j.jviromet.2021.1143391. journals2021
Mel KrajdenSmith, L. W., Racey, C. S., Gondara, L., Krajden, M., Lee, M., Martin, R. E., Stuart, G., Peacock, S., Coldman, A. J., Franco, E. L., van Niekerk, D., & Ogilvie, G. S. (2021). Women's acceptability of and experience with primary human papillomavirus testing for cervix screening: HPV FOCAL trial cross-sectional online survey results. BMJ open, 11(10), e052084. https://doi.org/10.1136/bmjopen-2021-0520841. journals2021
Mel KrajdenKidson, K. M., Park, J., Charles, M. K., Omar, M., Krajden, M., Wright, A. J., Hussaini, T., Kim, P., Chung, S. W., & Yoshida, E. M. (2021). Successful Liver Transplantation in a Patient With Acute COVID-19 Infection and Acute Liver Failure: A Case Report. Transplantation direct, 7(10), e747. https://doi.org/10.1097/TXD.00000000000012101. journals2021
Mel KrajdenBinka, M., Bartlett, S., Velásquez García, H. A., Darvishian, M., Jeong, D., Adu, P., Alvarez, M., Wong, S., Yu, A., Samji, H., Krajden, M., Wong, J., & Janjua, N. Z. (2021). Impact of COVID-19-related public health measures on HCV testing in British Columbia, Canada: An interrupted time series analysis. Liver international : official journal of the International Association for the Study of the Liver, 10.1111/liv.15074. Advance online publication. https://doi.org/10.1111/liv.150741. journals2021
Mel KrajdenPearce, M. E., Bartlett, S. R., Yu, A., Lamb, J., Reitz, C., Wong, S., Alvarez, M., Binka, M., Velásquez Garcia, H., Jeong, D., Clementi, E., Adu, P., Samji, H., Wong, J., Buxton, J., Yoshida, E., Elwood, C., Sauve, L., Pick, N., Krajden, M., €¦ Janjua, N. Z. (2021). Women in the 2019 hepatitis C cascade of care: findings from the British Columbia Hepatitis Testers cohort study. BMC women's health, 21(1), 330. https://doi.org/10.1186/s12905-021-01470-71. journals2021
Mel KrajdenLiu, M., Arora, R. K., & Krajden, M. (2021). Tests de détection rapides d€™antigènes pour le SRAS-CoV-2. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 193(23), E886€“E887. https://doi.org/10.1503/cmaj.202827-f1. journals2021
Mel KrajdenEvaluation of commercially available high-throughput SARS-CoV-2 serological assays for serosurveillance and related applicationsMars Stone, Eduard Grebe, Hasan Sulaeman, Clara Di Germanio, Honey Dave, Kathleen Kelly, Brad Biggerstaff, Bridgit O. Crews, Nam Tran, Keith R. Jerome, Thomas N. Denny, Boris Hogema, Mark Destree, Jefferson M. Jones, Natalie Thornburg, Graham Simmons, Mel Krajden, Steve Kleinman, Larry J. Dumont, Michael P. BuschmedRxiv 2021.09.04.21262414; doi: https://doi.org/10.1101/2021.09.04.212624141. journals2021
Mel KrajdenComparative single-dose mRNA and ChAdOx1 vaccine effectiveness against SARS-CoV-2, including early variants of concern: a test-negative design, British Columbia, CanadaDanuta M Skowronski, Solmaz Setayeshgar, Macy Zou, Natalie Prystajecky, John R Tyson, Hind Sbihi, Chris D Fjell, Eleni Galanis, Monika Naus, David M Patrick, Shiraz El Adam, May Ahmed, Shinhye Kim, Bonnie Henry, Linda M N Hoang, Manish Sadarangani, Agatha N Jassem, Mel KrajdenmedRxiv 2021.09.20.21263875; doi: https://doi.org/10.1101/2021.09.20.212638751. journals2021
Mel KrajdenCholette, F., Mesa, C., Harris, A., Ellis, H., Cachero, K., Lacap, P., Galipeau, Y., Langlois, M. A., Gingras, A. C., Yansouni, C. P., Papenburg, J., Cheng, M. P., Chakraborty, P., Stein, D. R., Van Caeseele, P., Bartlett, S., Krajden, M., Goldfarb, D., McGeer, A., Osiowy, C., €¦ COVID-19 Immunity Task Force (CITF) working group (2021). Dried blood spot specimens for SARS-CoV-2 antibody testing: A multi-site, multi-assay comparison. PloS one, 16(12), e0261003. https://doi.org/10.1371/journal.pone.02610031. journals2021
Mel KrajdenBeale, M. A., Marks, M., Cole, M. J., Lee, M. K., Pitt, R., Ruis, C., Balla, E., Crucitti, T., Ewens, M., Fernández-Naval, C., Grankvist, A., Guiver, M., Kenyon, C. R., Khairullin, R., Kularatne, R., Arando, M., Molini, B. J., Obukhov, A., Page, E. E., Petrovay, F., €¦ Thomson, N. R. (2021). Global phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis. Nature microbiology, 6(12), 1549€“1560. https://doi.org/10.1038/s41564-021-01000-z1. journals2021
Mel KrajdenWilton, J., Abdia, Y., Chong, M., Karim, M. E., Wong, S., MacInnes, A., Balshaw, R., Zhao, B., Gomes, T., Yu, A., Alvarez, M., Dart, R. C., Krajden, M., Buxton, J. A., Janjua, N. Z., & Purssell, R. (2021). Prescription opioid treatment for non-cancer pain and initiation of injection drug use: large retrospective cohort study. BMJ (Clinical research ed.), 375, e066965. https://doi.org/10.1136/bmj-2021-0669651. journals2021
Mel KrajdenGauthier, N., Nelson, C., Bonsall, M. B., Locher, K., Charles, M., MacDonald, C., Krajden, M., Chorlton, S. D., & Manges, A. R. (2021). Nanopore metagenomic sequencing for detection and characterization of SARS-CoV-2 in clinical samples. PloS one, 16(11), e0259712. https://doi.org/10.1371/journal.pone.02597121. journals2021
Mel KrajdenVelásquez García, H. A., Wilton, J., Smolina, K., Chong, M., Rasali, D., Otterstatter, M., Rose, C., Prystajecky, N., David, S., Galanis, E., McKee, G., Krajden, M., & Janjua, N. Z. (2021). Mental Health and Substance Use Associated with Hospitalization among People with COVID-19: A Population-Based Cohort Study. Viruses, 13(11), 2196. https://doi.org/10.3390/v131121961. journals2021
Mel KrajdenSekirov, I., Petric, M., Carruthers, E., Lawrence, D., Pidduck, T., Kustra, J., Laley, J., Lee, M. K., Chahil, N., Mak, A., Levett, P. N., Mendoza, E., Wood, H., Drebot, M., Krajden, M., & Morshed, M. (2021). Performance comparison of micro-neutralization assays based on surrogate SARS-CoV-2 and WT SARS-CoV-2 in assessing virus-neutralizing capacity of anti-SARS-CoV-2 antibodies. Access microbiology, 3(8), 000257. https://doi.org/10.1099/acmi.0.0002571. journals2021
Mel KrajdenWilton J, Abdia Y, Chong M, Karim M E, Wong S, MacInnes A et al. Prescription opioid treatment for non-cancer pain and initiation of injection drug use: large retrospective cohort study BMJ 2021; 375 :e066965 doi:10.1136/bmj-2021-0669651. journals2021
Mel KrajdenWilton, J., Abdia, Y., Chong, M., Karim, M. E., Wong, S., MacInnes, A., Balshaw, R., Zhao, B., Gomes, T., Yu, A., Alvarez, M., Dart, R. C., Krajden, M., Buxton, J. A., Janjua, N. Z., & Purssell, R. (2021). Prescription opioid treatment for non-cancer pain and initiation of injection drug use: large retrospective cohort study. BMJ (Clinical research ed.), 375, e066965. https://doi.org/10.1136/bmj-2021-0669651. journals2021
Mel KrajdenSekirov, I., Petric, M., Carruthers, E., Lawrence, D., Pidduck, T., Kustra, J., Laley, J., Lee, M. K., Chahil, N., Mak, A., Levett, P. N., Mendoza, E., Wood, H., Drebot, M., Krajden, M., & Morshed, M. (2021). Performance comparison of micro-neutralization assays based on surrogate SARS-CoV-2 and WT SARS-CoV-2 in assessing virus-neutralizing capacity of anti-SARS-CoV-2 antibodies. Access microbiology, 3(8), 000257. https://doi.org/10.1099/acmi.0.0002571. journals2021
Mel KrajdenVelásquez García, H. A., Wilton, J., Smolina, K., Chong, M., Rasali, D., Otterstatter, M., Rose, C., Prystajecky, N., David, S., Galanis, E., McKee, G., Krajden, M., & Janjua, N. Z. (2021). Mental Health and Substance Use Associated with Hospitalization among People with COVID-19: A Population-Based Cohort Study. Viruses, 13(11), 2196. https://doi.org/10.3390/v131121961. journals2021
Michael ChenBrahmadhi A, Chen MX, Wang SY, Cho YY, Yu MC, Lee CH, Tsai IL. Determination of fluoroquinolones in dried plasma spots by using microwave-assisted extraction coupled to ultra-high performance liquid chromatography-tandem mass spectrometry for therapeutic drug monitoring. J Pharm Biomed Anal. 2021 Feb 20;195:113821. doi: 10.1016/j.jpba.2020.113821. Epub 2020 Dec 2. PMID: 33317915.1. journals2021
Michael ChenChen MX, Su HH, Shiao CY, Chang YT, Chang MC, Kao CC, Wang SY, Shih HC, Tsai IL. Affinity Purification Coupled to Stable Isotope Dilution LC-MS/MS Analysis to Discover IgG4 Glycosylation Profiles for Autoimmune Pancreatitis. Int J Mol Sci. 2021 Oct 26;22(21):11527. doi: 10.3390/ijms222111527. PMID: 34768956; PMCID: PMC8584136.1. journals2021
Michael ChenFroehlich BC, Popp R, Sobsey CA, Ibrahim S, LeBlanc A, Mohammed Y, Buchanan M, Aguilar-Mahecha A, Pötz O, Chen MX, Spatz A, Basik M, Batist G, Zahedi RP, Borchers CH. A multiplexed, automated immuno-matrix assisted laser desorption/ionization mass spectrometry assay for simultaneous and precise quantitation of PTEN and p110α in cell lines and tumor tissues. Analyst. 2021 Oct 25;146(21):6566-6575. doi: 10.1039/d1an00165e. PMID: 34585690.1. journals2021
Muhammad MorshedVijh R, C Ghafari, A Hayden, M Schwandt, I Sekirov, M Morshed et al. 2021. Serological survey following SARS-COV-2 outbreaks at long-term care facilities in metro Vancouver, British Columbia: implications for outbreak management and infection control. American journal of infection control 49 (5), 649-6521. journals2021
Muhammad MorshedDM Skowronski, I Sekirov, S Sabaiduc, M Zou, M Morshed, D Lawrence et al. 2021. Low SARS-CoV-2 sero-prevalence based on anonymized residual sero-survey before and after first wave measures in British Columbia, Canada, March-May 2020. doi: https://doi.org/10.1101/2020.07.13.201531481. journals2021
Muhammad MorshedChiang LY, B Baumann, K Romanowski, D Kumar, JR Campbell,Djurdjev O, Morshed M et al. 2021. Latent Tuberculosis Therapy Outcomes in Dialysis Patients: A Retrospective Cohort. American Journal of Kidney Diseases 77 (5), 696-7031. journals2021
Muhammad MorshedMorshed MG, MK Lee, E Boyd, S Mak, E Fraser, J Nguyen, EA Dykstra et al. 2021. Passive Tick Surveillance and Detection of Borrelia Species in Ticks from British Columbia, Canada: 2002€“2018. Vector-Borne and Zoonotic Diseases. https://doi.org/10.1089/vbz.2020.27431. journals2021
Muhammad MorshedLowe CE, M Kiaii, L Aparicio, L Chinybaeva, S Coughlin, I Sekirov, Morshed MG, Leung V. 2021. Risk following a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) exposure from a nocturnal hemodialysis patient utilizing continuous positive airway pressure (CPAP). Infection Control & Hospital Epidemiology 42 (4), 491-4921. journals2021
Muhammad MorshedMorshed M, I Sekirov, M McLennan, PN Levett, N Chahil, A Mak et. Al. 2021. Comparative Analysis of Capillary vs Venous Blood for Serologic Detection of SARS-CoV-2 Antibodies by RPOC Lateral Flow Tests. Open Forum Infectious Diseases 8 (3), ofab0431. journals2021
Muhammad MorshedCharlton C, J Kanji, V Tran, J Kus, J Gubbay, C Osiowy, J Robinson, I Sekirov, M Drebott, T hatchette, S Stein, NE Gabalaway, A Lang, L Jiao, P levett, H Wood, C Therrien, LR Lindsey, M Morshed et al. 2021.  COVID-19: A year later: Practical guidance for clinical laboratories for SARS-CoV-2 serology testing. Canada Communicable Disease Report 47 (4), 171.1. journals2021
Muhammad MorshedMorshed M. 2021. SARS CoV-2 Indoor v outdoor transmission April 29.  NEWAGE. Bangladesh. https://www.newagebd.net/article/136616/indoor-v-outdoor-transmission1. journals2021
Muhammad MorshedMorshed M. 2021. COVID-19 vaccine fatigue and new variants. February 11, 2021. NEWAGE, Bangladesh https://www.newagebd.net/article/129801/covid-19-vaccine-fatigue-and-new-variants1. journals2021
Muhammad MorshedBeale MA, Marks M, Cole MJ, Lee MK, Pitt R, Ruis C, Balla E, Crucitti T, Ewens M, Fernández-Naval C, Grankvist A, Guiver M, Kenyon CR, Khairullin R, Kularatne R, Arando M, Molini BJ, Obukhov A, Page EE, Petrovay F, Rietmeijer C, Rowley D, Shokoples S, Smit E, Sweeney EL, Taiaroa G, Vera JH, Wennerås C, Whiley DM, Williamson DA, Hughes G, Naidu P, Unemo M, Krajden M, Lukehart SA, Morshed MG, Fifer H, Thomson NR. Global phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis. Nat Microbiol. 2021 Dec;6(12):1549-1560. doi: 10.1038/s41564-021-01000-z. Epub 2021 Nov 24. PMID: 34819643; PMCID: PMC8612932.1. journals2021
Muhammad MorshedValcourt EJ, Manguiat K, Robinson A, Lin YC, Abe KT, Mubareka S, Shigayeva A, Zhong Z, Girardin RC, DuPuis A, Payne A, McDonough K, Wang Z, Gasser R, Laumaea A, Benlarbi M, Richard J, Prévost J, Anand SP, Dimitrova K, Phillipson C, McGeer A, Gingras AC, Liang C, Petric M, Sekirov I, Morshed M, Finzi A, Drebot M, Wood H. Evaluating Humoral Immunity against SARS-CoV-2: Validation of a Plaque-Reduction Neutralization Test and a Multilaboratory Comparison of Conventional and Surrogate Neutralization Assays. Microbiol Spectr. 2021 Dec 22;9(3):e0088621. doi: 10.1128/Spectrum.00886-21. Epub 2021 Nov 17. PMID: 34787495; PMCID: PMC8597631.1. journals2021
Muhammad MorshedMcClymont E, Elwood C, Sekirov I, Morshed M, Levett P, Liu A, Jassem A, Sbihi H, Ogilvie G, Krajden M, Money D. Population SARS-CoV-2 Seroprevalence Using Antenatal Serum Samples in British Columbia, Canada. J Obstet Gynaecol Can. 2021 Nov;43(11):1242-1243. doi: 10.1016/j.jogc.2021.06.001. PMID: 34758903; PMCID: PMC8572370.1. journals2021
Muhammad MorshedStein DR, Osiowy C, Gretchen A, Thorlacius L, Fudge D, Lang A, Sekirov I, Morshed M, Levett PN, Tran V, Kus JV, Gubbay J, Mohan V, Charlton C, Kanji JN, Tipples G, Serhir B, Therrien C, Roger M, Jiao L, Zahariadis G, Needle R, Gilbert L, Desnoyers G, Garceau R, Bouhtiauy I, Longtin J, El-Gabalawy N, Dibernardo A, Lindsay LR, Drebot M; Canadian Public Health Laboratory Network (CPHLN) Serology Task Force. Evaluation of commercial SARS-CoV-2 serological assays in Canadian public health laboratories. Diagn Microbiol Infect Dis. 2021 Nov;101(3):115412. doi: 10.1016/j.diagmicrobio.2021.115412. Epub 2021 Apr 24. PMID: 34425450; PMCID: PMC8377389.1. journals2021
Muhammad MorshedSomily AM, Khan MA, Morshed M. The Laboratory Diagnosis of Clostridioides difficile Infection: An update of current laboratory practice. J Infect Dev Ctries. 2021 Oct 31;15(10):1364-1375. doi: 10.3855/jidc.13217. PMID: 34780357.1. journals2021
Muhammad MorshedTeman SJ, Gaydos JK, Norman SA, Huggins JL, Lambourn DM, Calambokidis J, Ford JKB, Hanson MB, Haulena M, Zabek E, Cottrell P, Hoang L, Morshed M, Garner MM, Raverty S. Epizootiology of a Cryptococcus gattii outbreak in porpoises and dolphins from the Salish Sea. Dis Aquat Organ. 2021 Oct 21;146:129-143. doi: 10.3354/dao03630. PMID: 34672263.1. journals2021
Muhammad MorshedAhmed-Bentley J, Roman S, Mirzanejad Y, Fraser E, Hoang L, Young EJ, Morshed M, Deans G. Laboratory Exposures from an Unsuspected Case of Human Infection with Brucella canis. Emerg Infect Dis. 2021 Sep;27(9):2489-2491. doi: 10.3201/eid2709.204701. PMID: 34424169; PMCID: PMC8386805.1. journals2021
Muhammad MorshedSekirov I, Barakauskas VE, Simons J, Cook D, Bates B, Burns L, Masud S, Charles M, McLennan M, Mak A, Chahil N, Vijh R, Hayden A, Goldfarb D, Levett PN, Krajden M, Morshed M. SARS-CoV-2 serology: Validation of high-throughput chemiluminescent immunoassay (CLIA) platforms and a field study in British Columbia. J Clin Virol. 2021 Sep;142:104914. doi: 10.1016/j.jcv.2021.104914. Epub 2021 Jul 16. PMID: 34304088; PMCID: PMC8282439.1. journals2021
Muhammad MorshedCharlton C, J Kanji, V Tran, J Kus, J Gubbay, C Osiowy, J Robinson, I Sekirov, M Drebott, T hatchette, S Stein, NE Gabalaway, A Lang, L Jiao, P levett, H Wood, C Therrien, LR Lindsey, M Morshed et al. 2021.  COVID-19: A year later: Practical guidance for clinical laboratories for SARS-CoV-2 serology testing. Canada Communicable Disease Report 47 (4), 1711. journals2021
Muhammad MorshedMorshed M 2021.  (in Bengali). Desh Rupantor. Dec 22, 2021. https://www.deshrupantor.com/editorial-news/2021/12/22/334542?fbclid=IwAR3j5mJ_J78jiGS7IOQYXbG2WN_VHgFYnXvdm3ursdXpG7Yr8YFUPomrYQo1. journals2021
Muhammad MorshedMorshed M. 2021. COVID-19: A humble plea from a microbiologist. April 23, 2021. The Business Standard, Bangladesh. https://www.tbsnews.net/thoughts/covid-19-humble-plea-microbiologist-2360621. journals2021
Nancy MaticChorlton SD, Ritchie G, Lawson T, McLachland E, Romney MG, Matic N, Lowe CF. 2021. Next-generation sequencing for cytomegalovirus antiviral resistance genotyping in a clinical virology laboratory. Antiviral Res192:105123. doi: 10.1016/j.antiviral.2021.105123. SA1. journals2021
Nancy MaticMatic N, Stefanovic A, Leung V, Lawson T, Ritchie G, Li L, Champagne S, Romney MG, Lowe CF. 2021. Practical challenges to the clinical implementation of saliva for SARS-CoV-2 detection. Eur J Clin Microbiol Infect Dis 40(2):447-450. doi: 10.1007/s10096-020-04090-5. FA1. journals2021
Nancy MaticMatic N, Lawson T, Ritchie G, Stefanovic A, Leung V, Champagne S, Romney MG, Lowe CF. Automated molecular testing of saliva for SARS-CoV-2 detection. 2021. Diagn Microbiol Infect Dis 100(1): 115324. doi: 10.1016/j.diagmicrobio.2021.1153241. journals2021
Nancy MaticMatic N, Lowe CF, Ritchie G, Stefanovic A, Lawson T, Jang W, Young M Dong W, Brumme AL, Brumme CJ, Leung V, Romney MG. 2021. Rapid detection of SARS-CoV-2 variants of concern, includng B.1.1.28/P.1, in British Columbia, Canada. Emerg Infect Dis 27(6). doi: 10.3201/eid2706.210532. FA1. journals2021
Nancy MaticKinloch NN, Ritchie G, Dong W, Cobarrubias KD, Sudderuddin H, Lawson T, Matic N, Montaner JSG, Leung V, Romney MG, Lowe CF, Brumme CJD, Brumme ZL. 2021. SARS-CoV-2 RNA quantification using droplet digital RT-PCR. J Mol Diagn S1525-1578(21)00136-7. doi: 10.1016/j.jmoldx.2021.04.014. CA1. journals2021
Nancy MaticReich N, Lowe CF, Puddicombe D, Matic N, Greiner J, Simons J, Leung V, Chu T, Naik H, Myles N, Burns L, Romney MG, Ritchie G, Champagne S, Dooley K, Sekirov I, Stefanovic A. 2021. Repeat virological and serological profiles in hospitalized patients initially tested by nasopharyngeal RT-PCR for SARS-CoV-2. J Med Virol. doi: 10.1002/jmv.27227. CA1. journals2021
Narges HadjesfandiariHadjesfandiari N, Khorshidfar M, Devine DV. Current Understanding of the Relationship between Blood Donor Variability and Blood Component Quality. Int J Mol Sci. 2021 Apr 11;22(8):3943. doi: 10.3390/ijms22083943. PMID: 33920459; PMCID: PMC8069744.1. journals2021
Narges HadjesfandiariHadjesfandiari N, Levin E, Serrano K, Yi QL, Devine DV. Risk analysis of transfusion of cryoprecipitate without consideration of ABO group. Transfusion. 2021 Jan;61(1):29-34. doi: 10.1111/trf.16125. Epub 2020 Oct 10. PMID: 33037661.1. journals2021
Natalie PrystajeckyCoombe M, Iwasawa S, Byers KA, Prystajecky N, Hsiao W, Patrick DM, Himsworth CG. 2021. A systematic review and narrative synthesis of the use of environmental samples for the surveillance of avian influenza viruses in wild waterbirds. Journal of Wildlife Diseases. 57(1):1-18.1. journals2021
Natalie PrystajeckyChik AHS, Glier MB, Servos M, Mangat CS, Pang XL, Qiu Y, D'Aoust PM, Burnet JB, Delatolla R, Dorner S, Geng Q, Giesy Jr JP, McKay RM, Mulvey MR, Prystajecky N, Srikanthan N, Xie Y, Conant B, Hrudey SE, Canadian SARS-CoV-2 Inter-Laboratory Consortium. 2021. Comparison of approaches to quantify SARS-CoV-2 in wastewater using RT-qPCR: Results and implications from a collaborative inter-laboratory study in Canada. Journal of Environmental Sciences. 107:218-229.1. journals2021
Natalie PrystajeckyHogan CA, Sbihi H, Jassem A, Prystajecky N, Tyson JR, Lee TD, Tsang F, Ng C, Janz L, Romney MG, Hoang L. 2021. Optimizing SARS-CoV-2 Variant of Concern Screening: Experience from British Columbia, Canada, Early 2021. medRxiv.1. journals2021
Natalie PrystajeckyNikiforuk AM, Kuchinski KS, Twa DDW, Lukac CD, Sbihi H, Basham CA, Steidl C, Prystajecky NA, Jassem AN, Krajden M, Patrick DM, Sekirov I. 2021. The contrasting role of nasopharyngeal angiotensin converting enzyme 2 (ACE2) transcription in SARS-CoV-2 infection: A cross-sectional study of people tested for COVID-19 in British Columbia, Canada. EBioMedicine. 66:103316.1. journals2021
Natalie PrystajeckyLin X, Glier M, Kuchinski K, Ross-Van Mierlo T, McVea D, Tyson JR, Prystajecky N, Ziels RM. 2021. Assessing Multiplex Tiling PCR Sequencing Approaches for Detecting Genomic Variants of SARS-CoV-2 in Municipal Wastewater. mSystems. 6(5):e0106821.1. journals2021
Natalie PrystajeckyCaza M, Hogan CA, Jassem A, Prystajecky N, Hadzic A, Wilmer A. 2021. Evaluation of the clinical and analytical performance of the Seegene allplex„¢ SARS-CoV-2 variants I assay for the detection of variants of concern (VOC) and variants of interests (VOI). Journal of Clinical Virology. 144:104996.1. journals2021
Natalie PrystajeckyHarris R, Tchao C, Prystajecky N, Cutler J, Austin JW. 2021. A summary of surveillance, morbidity and microbiology of laboratory-confirmed cases of infant botulism in Canada, 1979-2019. Canada Communicable Disease Report. 47(78):322-328.1. journals2021
Natalie PrystajeckyHogan CA, Jassem AN, Sbihi H, Joffres Y, Tyson JR, Noftall K, Taylor M, Lee T, Fjell C, Wilmer A, Galbraith J, Romney MG, Henry B, Krajden M, Galanis E, Prystajecky N, Hoang L. 2021. Rapid Increase in SARS-CoV-2 P.1 Lineage Leading to Codominance with B.1.1.7 Lineage, British Columbia, Canada, January-April 2021. Emerging Infectious Diseases. 27(11):2802-2809.1. journals2021
Natalie PrystajeckySabet F, Gauthier B, Siddiqui M, Wilmer A, Prystajecky N, Rydings P, Andrews M, Pollock S. 2021. COVID-19 outbreak in a long-term care facility in Kelowna, British Columbia after rollout of COVID-19 vaccine in March 2021. Canada Communicable Disease Report. 47(12):543-552.1. journals2021
Natalie PrystajeckyVelásquez García HA, Wilton J, Smolina K, Chong M, Rasali D, Otterstatter M, Rose C, Prystajecky N, David S, Galanis E, McKee G, Krajden M, Janjua NZ. 2021. Mental Health and Substance Use Associated with Hospitalization among People with COVID-19: A Population-Based Cohort Study. Viruses. 13(11):2196.1. journals2021
Naveena SinghGaba F, Robbani S, Singh N, McCluggage WG, Wilkinson N, Ganesan R, Bryson G, Rowlands G, Tyson C, Arora R, Saridogan E, Hanson H, Burnell M, Legood R, Evans DG, Menon U, Manchanda R; PROTECTOR team. Preventing Ovarian Cancer through early Excision of Tubes and late Ovarian Removal (PROTECTOR): protocol for a prospective non-randomised multi-center trial. Int J Gynecol Cancer. 2021 Feb;31(2):286-291. doi: 10.1136/ijgc-2020-001541. Epub 2020 Sep 8. PMID: 32907814.1. journals2021
Naveena SinghSingh N, Wong R, Tchrakian N, Allen SG, Clarke B, Gilks CB. Interpretation of mismatch repair protein expression using obsolete criteria results in discrepancies with microsatellite instability and mutational testing results. Comment on Hechtman et al. Mod Pathol 2020; 33:871-879. Mod Pathol. 2021 May;34(5):1031-1032. doi: 10.1038/s41379-020-00680-y. Epub 2020 Sep 26. PMID: 32980858.1. journals2021
Naveena SinghCasey L, Singh N. POLE, MMR, and MSI Testing in Endometrial Cancer: Proceedings of the ISGyP Companion Society Session at the USCAP 2020 Annual Meeting. Int J Gynecol Pathol. 2021 Jan;40(1):5-16. doi: 10.1097/PGP.0000000000000710. PMID: 33290350.1. journals2021
Naveena SinghKalsi JK, Ryan A, Gentry-Maharaj A, Margolin-Crump D, Singh N, Burnell M, Benjamin E, Apostolidou S, Habib M, Massingham S, Karpinskyj C, Woolas R, Widschwendter M, Fallowfield L, Campbell S, Skates S, McGuire A, Parmar M, Jacobs I, Menon U. Completeness and accuracy of national cancer and death registration for outcome ascertainment in trials-an ovarian cancer exemplar. Trials. 2021 Jan 25;22(1):88. doi: 10.1186/s13063-020-04968-x. PMID: 33494753; PMCID: PMC7831170.1. journals2021
Naveena SinghCohen PA, Powell A, Böhm S, Gilks CB, Stewart CJR, Meniawy TM, Bulsara M, Avril S, Brockbank EC, Bosse T, de Azevedo Focchi GR, Ganesan R, Glasspool RM, Howitt BE, Kim HS, Lee JY, Le ND, Lockley M, Manchanda R, Mandalia T, McCluggage WG, McNeish I, Midha D, Srinivasan R, Tan YY, van der Griend R, Yunokawa M, Zannoni GF; HGSC CRS Collaborative Network (Supplementary 1), Singh N. Corrigendum to "Pathological chemotherapy response score is prognostic in tubo-ovarian high-grade serous carcinoma: A systematic review and meta-analysis of individual patient data" Gynecol. Oncol. 154 (2019) 441-448. Gynecol Oncol. 2021 Apr;161(1):328-329. doi: 10.1016/j.ygyno.2021.01.032. Epub 2021 Feb 5. Erratum for: Gynecol Oncol. 2019 Aug;154(2):441-448. PMID: 33551198.1. journals2021
Naveena SinghGaba F, Goyal S, Marks D, Chandrasekaran D, Evans O, Robbani S, Tyson C, Legood R, Saridogan E, McCluggage WG, Hanson H, Singh N, Evans DG, Menon U, Manchanda R; PROTECTOR team. Surgical decision making in premenopausal BRCA carriers considering risk-reducing early salpingectomy or salpingo-oophorectomy: a qualitative study. J Med Genet. 2021 Feb 10:jmedgenet-2020-107501. doi: 10.1136/jmedgenet-2020-107501. Epub ahead of print. PMID: 33568437.1. journals2021
Naveena SinghPark KJ, Cabrero IA, Fadare O, Hoang L, Kiyokawa T, Oliva E, Parra-Herran C, Rabban JT, Roma A, Singh N, Soslow R, Stolnicu S, Huvila J, Leung S, Gilks CB. Online Training and Self-assessment in the Histopathologic Classification of Endocervical Adenocarcinoma and Diagnosis of Pattern of Invasion: Evaluation of Participant Performance. Int J Gynecol Pathol. 2021 Mar 1;40(Suppl 1):S14-S23. doi: 10.1097/PGP.0000000000000757. PMID: 33570861; PMCID: PMC7969175.1. journals2021
Naveena SinghTalia KL, Oliva E, Rabban JT, Singh N, Stolnicu S, McCluggage WG. Grading of Endocervical Adenocarcinomas: Review of the Literature and Recommendations From the International Society of Gynecological Pathologists. Int J Gynecol Pathol. 2021 Mar 1;40(Suppl 1):S66-S74. doi: 10.1097/PGP.0000000000000741. PMID: 33570864; PMCID: PMC7969159.1. journals2021
Naveena SinghPark KJ, Roma A, Singh N, Gilks CB, Oliva E, Abu-Rustum N, Ramirez PT, McCluggage WG. Tumor Staging of Endocervical Adenocarcinoma: Recommendations From the International Society of Gynecological Pathologists. Int J Gynecol Pathol. 2021 Mar 1;40(Suppl 1):S92-S101. doi: 10.1097/PGP.0000000000000758. PMID: 33570866; PMCID: PMC7969160.1. journals2021
Naveena SinghBurnell M, Gentry-Maharaj A, Skates SJ, Ryan A, Karpinskyj C, Kalsi J, Apostolidou S, Singh N, Dawnay A, Woolas R, Fallowfield L, Campbell S, McGuire A, Jacobs IJ, Parmar M, Menon U. UKCTOCS update: applying insights of delayed effects in cancer screening trials to the long-term follow-up mortality analysis. Trials. 2021 Mar 1;22(1):173. doi: 10.1186/s13063-021-05125-8. PMID: 33648562; PMCID: PMC7919310.1. journals2021
Naveena SinghKriplani D, Olivar AA, Tchrakian N, Butcher D, Casey L, Crook JA, Deo N, Dilley J, Griffiths R, Hogg M, Jeyarajah AR, Khan SJ, Lawrence A, Lee A, Leen SL, Leitch-Devlin L, Manchanda R, Masood M, Nyarko E, Okaro E, Phadnis S, Trevisan G, Tsang J, Vimplis S, Wilmott F, Brockbank E, Singh N. Concise Reporting of Benign Endometrial Biopsies is an Acceptable Alternative to Descriptive Reporting. Int J Gynecol Pathol. 2021 Feb 25. doi: 10.1097/PGP.0000000000000761. Epub ahead of print. PMID: 33664191.1. journals2021
Naveena SinghKalsi J, Gentry-Maharaj A, Ryan A, Singh N, Burnell M, Massingham S, Apostolidou S, Sharma A, Williamson K, Seif M, Mould T, Woolas R, Dobbs S, Leeson S, Fallowfield L, Skates SJ, Parmar M, Campbell S, Jacobs I, McGuire A, Menon U. Performance Characteristics of the Ultrasound Strategy during Incidence Screening in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Cancers (Basel). 2021 Feb 18;13(4):858. doi: 10.3390/cancers13040858. PMID: 33670571; PMCID: PMC7922843.1. journals2021
Naveena SinghPalicelli A, Giaccherini L, Zanelli M, Bonasoni MP, Gelli MC, Bisagni A, Zanetti E, De Marco L, Torricelli F, Manzotti G, Gugnoni M, D'Ippolito G, Falbo AI, Sileo FG, Aguzzoli L, Mastrofilippo V, Bonacini M, De Giorgi F, Ricci S, Bernardelli G, Ardighieri L, Zizzo M, De Leo A, Santandrea G, de Biase D, Ragazzi M, Dalla Dea G, Veggiani C, Carpenito L, Sanguedolce F, Asaturova A, Boldorini R, Disanto MG, Goia M, Wong RW, Singh N, Mandato VD. How Can We Treat Vulvar Carcinoma in Pregnancy? A Systematic Review of the Literature. Cancers (Basel). 2021 Feb 17;13(4):836. doi: 10.3390/cancers13040836. PMID: 33671249; PMCID: PMC7921964.1. journals2021
Naveena SinghMcCluggage WG, Rabban JT, Singh N, Oliva E. Survey Results on Pathologic Aspects of Endocervical Adenocarcinoma by the International Society of Gynecological Pathologists. Int J Gynecol Pathol. 2021 Mar;40 Suppl 1(Iss 2 Suppl 1):S4-S13. doi: 10.1097/PGP.0000000000000744. PMID: 33687170; PMCID: PMC7969156.1. journals2021
Naveena SinghSingh N, Rabban JT. The ISGyP Endocervical Adenocarcinoma Project: Master Plan Summary, Acknowledgment of Participants, and Participant Responses to Final Recommendations of the Expert Panels. Int J Gynecol Pathol. 2021 Mar;40 Suppl 1(Iss 2 Suppl 1):S111-S123. doi: 10.1097/PGP.0000000000000760. PMID: 33687171; PMCID: PMC7969173.1. journals2021
Naveena SinghDundr P, Singh N, Nožičková B, Němejcová K, Bártů M, Stružinská I. Primary mucinous ovarian tumors vs. ovarian metastases from gastrointestinal tract, pancreas and biliary tree: a review of current problematics. Diagn Pathol. 2021 Mar 11;16(1):20. doi: 10.1186/s13000-021-01079-2. PMID: 33706757; PMCID: PMC7953678.1. journals2021
Naveena SinghWang L, Piskorz A, Bosse T, Jimenez-Linan M, Rous B, Gilks CB, Brenton JD, Singh N, Köbel M. Immunohistochemistry and Next-generation Sequencing Are Complementary Tests in Identifying PTEN Abnormality in Endometrial Carcinoma Biopsies. Int J Gynecol Pathol. 2021 Mar 15. doi: 10.1097/PGP.0000000000000763. Epub ahead of print. PMID: 33720084.1. journals2021
Naveena SinghVermij L, Singh N, Leon-Castillo A, Horeweg N, Oosting J, Carlson J, Smit V, Gilks B, Bosse T. Performance of a HER2 testing algorithm specific for p53-abnormal endometrial cancer. Histopathology. 2021 Oct;79(4):533-543. doi: 10.1111/his.14381. Epub 2021 Jul 5. PMID: 33835523; PMCID: PMC8518500.1. journals2021
Naveena SinghMenon U, Gentry-Maharaj A, Burnell M, Singh N, Ryan A, Karpinskyj C, Carlino G, Taylor J, Massingham SK, Raikou M, Kalsi JK, Woolas R, Manchanda R, Arora R, Casey L, Dawnay A, Dobbs S, Leeson S, Mould T, Seif MW, Sharma A, Williamson K, Liu Y, Fallowfield L, McGuire AJ, Campbell S, Skates SJ, Jacobs IJ, Parmar M. Ovarian cancer population screening and mortality after long-term follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial. Lancet. 2021 Jun 5;397(10290):2182-2193. doi: 10.1016/S0140-6736(21)00731-5. Epub 2021 May 12. PMID: 33991479; PMCID: PMC8192829.1. journals2021
Naveena SinghChandrasekaran D, Sobocan M, Blyuss O, Miller RE, Evans O, Crusz SM, Mills-Baldock T, Sun L, Hammond RFL, Gaba F, Jenkins LA, Ahmed M, Kumar A, Jeyarajah A, Lawrence AC, Brockbank E, Phadnis S, Quigley M, El Khouly F, Wuntakal R, Faruqi A, Trevisan G, Casey L, Burghel GJ, Schlecht H, Bulman M, Smith P, Bowers NL, Legood R, Lockley M, Wallace A, Singh N, Evans DG, Manchanda R. Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST Study. Cancers (Basel). 2021 Aug 27;13(17):4344. doi: 10.3390/cancers13174344. PMID: 34503154; PMCID: PMC8431198.1. journals2021
Naveena SinghRockall AG, Barwick TD, Wilson W, Singh N, Bharwani N, Sohaib A, Nobbenhuis M, Warbey V, Miquel M, Koh DM, De Paepe KN, Martin-Hirsch P, Ghaem-Maghami S, Fotopoulou C, Stringfellow H, Sundar S, Manchanda R, Sahdev A, Hackshaw A, Cook GJ; MAPPING Study Group. Diagnostic Accuracy of FEC-PET/CT, FDG-PET/CT, and Diffusion-Weighted MRI in Detection of Nodal Metastases in Surgically Treated Endometrial and Cervical Carcinoma. Clin Cancer Res. 2021 Dec 1;27(23):6457-6466. doi: 10.1158/1078-0432.CCR-21-1834. Epub 2021 Sep 15. PMID: 34526364.1. journals2021
Nevio CimolaiCimolai, N. €œRe-analysis of Quarantine for COVID-19 with Emerging Data" American Journal of Obstetrics & Gynecology Maternal Fetal Medicine 2021 Jan;3(1):100291.1. journals2021
Nicholas AuMcGinnis E, Yang D, Au N, Morrison D, Chipperfield KM, Setiadi AF, Liu L, Tsang A, Vercauteren SM. Clinical and laboratory features associated with myeloperoxidase expression in pediatric B-lymphoblastic leukemia. Cytometry B Clin Cytom 2021;100(4):446-453.1. journals2021
Paula BlancoAhmed S, Blanco P, MacDonald DA, Hundemer GL. The Case | Nephrotic syndrome in a patient with chronic lymphocytic leukemia. Kidney Int. 2021 Mar;99(3):777-778. doi: 10.1016/j.kint.2020.08.038. PMID: 33637210.1. journals2021
Pedro SequeiraFarinhaNicole Thomas, Kostiantyn Dreval, Daniela S. Gerhard, Laura K. Hilton, Jeremy S. Abramson, Nancy L. Bartlett, Jeffrey Bethony, Jay Bowen, Anthony C. Bryan, Corey Casper, Manuela Cruz, Maureen A. Dyer, Pedro Farinha, Julie M. Gastier-Foster, Alina S. Gerrie, Bruno M. Grande, Timothy Greiner, Nicholas B. Griner, Thomas G. Gross, Nancy L. Harris, John D. Irvin, Elaine S. Jaffe, Fabio E. Leal, Jean Paul Martin, Marie-Reine Martin, Sam M. Mbulaiteye, Charles G. Mullighan, Andrew J. Mungall, Karen Mungall, Constance Namirembe, Ariela Noy, Martin D. Ogwang, Jackson Orem, German Ott, Hilary Petrello, Steven J. Reynolds, Graham Slack, Shaghayegh Soudi, Steven H. Swerdlow, Alexandra Traverse-Glehen, Wyndham H. Wilson, Jasper Wong, Marco A. Marra, Louis M. Staudt, David W. Scott, Ryan D. Morin. Genetic Subgroups Inform on Pathobiology in Adult and Pediatric Burkitt Lymphoma. medRxiv December 8th 2021. doi: https://doi.org/10.1101/2021.12.05.212672161. journals2021
Pedro SequeiraFarinhaUrban R, Chow R, Pickles T, Chan M, Livergant J, Gerrie AS, Freeman C, Sehn L, Scott DW, Villa D, Farinha P, Gondara L, Savage KJ, Lo AC. The impact of surveillance imaging after curative-intent radiotherapy for limited-stage follicular lymphoma. Br J Haematol. 2021 Nov 4. doi: 10.1111/bjh.17684. Online ahead of print. PMID: 347344181. journals2021
Pedro SequeiraFarinhaShopsowitz KE, TuckerT, Bahmanyar M, Farinha P. Diffuse large B-cell Lymphoma versus Burkitt lymphoma with discordant diagnostic cytogenetics: Morphology trumps. eJHaem.2021;2:889€“890. https://doi.org/10.1002/jha2.3181. journals2021
Pedro SequeiraFarinhaAoki T, Chong LC, Takata K, Milne K, Marshall A, Chavez EA, Miyata-Takata T, Ben-Neriah S, Unrau D, Telenius A, Boyle M, Weng AP, Savage KJ, Scott DW, Farinha P, Shah SP, Nelson BH, Steidl C. Single-cell profiling reveals the importance of CXCL13/CXCR5 axis biology in lymphocyte-rich classic Hodgkin lymphoma. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41). doi: 10.1073/pnas.2105822118. PubMed PMID: 34615710; PubMed Central PMCID: PMC8521678.1. journals2021
Pedro SequeiraFarinhaCheng PTM, Villa D, Tonseth RP, Scott DW, Gerrie AS, Freeman CL, Pickles T, Lo AC, Farinha P, Craig JW, Slack GW, Gascoyne RD, Bénard F, Wilson D, Skinnider B, Connors JM, Sehn LH, Savage KJ. Outcome of limited-stage nodular lymphocyte-predominant Hodgkin lymphoma and the impact of a PET-adapted approach. Blood Adv. 2021 Sep 28;5(18):3647-3655. doi: 10.1182/bloodadvances.2021004375. PubMed PMID: 34438445.1. journals2021
Pedro SequeiraFarinhaNowicka M, Hilton LK, Ashton-Key M, Hargreaves CE, Lee C, Foxall R, Carter MJ, Beers SA, Potter KN, Bolen CR, Klein C, Knapp A, Mir F, Rose-Zerilli M, Burton C, Klapper W, Scott DW, Sehn LH, Vitolo U, Martelli M, Trneny M, Rushton CK, Slack GW, Farinha P, Strefford JC, Oestergaard MZ, Morin RD, Cragg MS. Prognostic significance of FCGR2B expression for the response of DLBCL patients to rituximab or obinutuzumab treatment. Blood Adv. 2021 Aug 10;5(15):2945-2957. doi: 10.1182/bloodadvances.2021004770. PubMed PMID: 34323958; PubMed Central PMCID: PMC8361458.1. journals2021
Pedro SequeiraFarinhaRoberto MP, Varano G, Vinas-Castells R, Holmes AB, Kumar R, Pasqualucci L, Farinha P, Scott DW, Dominguez-Sola D. Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis. Immunity. 2021 Aug 10;54(8):1807-1824.e14. doi: 10.1016/j.immuni.2021.07.009. PubMed PMID: 34380064; PubMed Central PMCID: PMC8475267.1. journals2021
Pedro SequeiraFarinhaPunnoose E, Peale FV, Szafer-Glusman E, Lei G, Bourgon R, Do AD, Kim E, Zhang L, Farinha P, Gascoyne RD, Munoz FJ, Martelli M, Mottok A, Salles GA, Sehn LH, Seymour JF, Trnĕný M, Oestergaard MZ, Mundt KE, Vitolo U. BCL2 Expression in First-Line Diffuse Large B-Cell Lymphoma Identifies a Patient Population With Poor Prognosis. Clin Lymphoma Myeloma Leuk. April 20211. journals2021
Pedro SequeiraFarinhaDuns G, Viganò E, Ennishi D, Sarkozy C, Hung SS, Chavez EA, Takata K, Rushton C, Jiang A, Ben-Neriah S, Woolcock B, Slack GW, Hsi ED, Craig JW, Hilton LK, Shah S, Farinha P, Mottok A, Gascoyne RD, Morin RD, Savage KJ, Scott DW, Steidl C. Characterization of DLBCL with a PMBL gene expression signature. Blood. 2021 Mar 8;. doi: 10.1182/blood.2020007683. [Epub ahead of print] PubMed PMID: 33684939.1. journals2021
Pedro SequeiraFarinhaFreeman CL, Savage KJ, Villa D, Scott DW, Srour L, Gerrie AS, Brown MJ, Slack GW, Farinha P, Skinnider B, Morris J, Bénard F, Aquino-Parsons C, Lo A, Pickles T, Wilson D, Tonseth P, Connors JM, Sehn L. Long-Term Results of PET-Guided Radiation in Advanced-Stage Diffuse Large B-Cell Lymphoma Patients Treated with R-CHOP. Blood. 2020 Sep 1;. doi: 10.1182/blood.2020005846. [Epub ahead of print] PubMed PMID: 32871586.1. journals2021
Peter SchubertSchubert P, Culibrk L, Culibrk B, Conway EM, Goodrich RP, Devine DV. Releasates of riboflavin/UV-treated platelets: Microvesicles suppress cytokine-mediated endothelial cell migration/proliferation. Transfusion. 2021, in press1. journals2021
Peter SchubertArbaeen AF, Schubert P, Sheffield WP, Devine DV. Pathogen reduction of whole blood: Supplementing fibrinogen partly corrects clot formation in a massive transfusion model. Transfusion. 2021, in press1. journals2021
Peter SchubertSchubert P, Johnson L, Culibrk B, Chen Z, Tan S, Marks DC,  Devine DV. Reconstituted cryopreserved platelets synthesize proteins during short-term storage and packaging a defined subset into microvesicles. Transfusion 2021, under review.1. journals2021
Peter SchubertSchubert P, Chen Z, Bhakta V, Culibrk B, Wambolt R, Sheffield WP, Devine DV, McTaggart K. Cold-stored leukoreduced whole blood: extending the time between donation and filtration has minimal impact on in vitro quality. Transfusion 2021, under revision.1. journals2021
Peter WatsonTarling T, Matzke L, Rush A, Gali B, Byrne JA, Watson PH.  Vignettes to illustrate the value of tumor biobanks in cancer research. Biopreserv Biobank. Biopreserv Biobank. 2021 Jun 24. doi: 10.1089/bio.2021.0002. PMID: 341653561. journals2021
Peter WatsonCarvalho K, Gali B, LeBlanc J, Matzke L, Watson PH.  A Permission to Contact (PTC) platform is an efficient and cost-effective enrollment method for a biobank to create study-specific research cohorts. Biopreserv Biobank. 2021 Jan 18. doi: 10.1089/bio.2020.0114. PMID: 334641751. journals2021
Peter WatsonKilgour MK, MacPherson S, Zacharias L, Keyes S, Pauly B, Allard B, Smazynski J, Watson PH, Stagg J, Nelson BH, DeBerardinis RJ, Hamilton PT, Lum JL. 1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer. Science Advances Sci Adv. 2021 Jan 20;7(4):eabe1174. doi: 10.1126/sciadv.abe1174. Print 2021 Jan. PMID: 335239301. journals2021
Peter WatsonByrne JA, Carpenter JE, Carter C, Phillips K, Braye S, Watson PH, Rush A. Building Research Support Capacity across Human Health Biobanks during the COVID-19 Pandemic. Biomark Insights. 2021 Jun 14;16:11772719211024100. doi: 10.1177/11772719211024100.. PMID: 34177256 1. journals2021
Peter WatsonMatzke L, Tarling T, Gali B, Dee, S, LeBlanc J, Vercauteren S, Watson PH.  Finding the value in biobanks €“ enhancing the CTRNet locator. Biopreserv Biobank. 2021 Jul 12. doi: 10.1089/bio.2021.0043. PMID: 342522931. journals2021
Peter WatsonO€™Donoghue S, Dee S, Byrne JA, and Watson PH. How many research biobanks are there? Biopreserv Biobank. 2021 Sep 28. doi: 10.1089/bio.2021.0063. Online ahead of print. PMID: 345822551. journals2021
Peter WatsonWotton L, Gali B, Carvalho K, Tarling T, Matzke L, Watson PH. Analysis of Trends in Biospecimen Complexity in Cancer Research over Two Decades. Biopreserv Biobank. 2021 Sep 9. doi: 10.1089/bio.2021.0078. Online ahead of print. PMID: 345155171. journals2021
Peter WatsonEl Bairi K, Haynes HR, Blackley E, Fineberg S, Shear J, Turner S, de Freitas JR, Sur D, Amendola LC, Gharib M, Kallala A, Arun I, Azmoudeh-Ardalan F, Fujimoto L, Sua LF, Liu SW, Lien HC, Kirtani P, Balancin M, El Attar H, Guleria P, Yang W, Shash E, Chen IC, Bautista V, Do Prado Moura JF, Rapoport BL, Castaneda C, Spengler E, Acosta-Haab G, Frahm I, Sanchez J, Castillo M, Bouchmaa N, Md Zin RR, Shui R, Onyuma T, Yang W, Husain Z, Willard-Gallo K, Coosemans A, Perez EA, Provenzano E, Ericsson PG, Richardet E, Mehrotra R, Sarancone S, Ehinger A, Rimm DL, Bartlett JMS, Viale G, Denkert C, Hida AI, Sotiriou C, Loibl S, Hewitt SM, Badve S, Symmans WF, Kim RS, Pruneri G, Goel S, Francis PA, Inurrigarro G, Yamaguchi R, Garcia-Rivello H, Horlings H, Afqir S, Salgado R, Adams S, Kok M, Dieci MV, Michiels S, Demaria S, Loi S; International Immuno-Oncology Biomarker Working Group. The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group. NPJ Breast Cancer. 2021 Dec 1;7(1):150. doi: 10.1038/s41523-021-00346-1. PMID: 348533551. journals2021
Peter WatsonRush A, Catchpoole DR, Reaiche-Miller G, Gilbert T, Ng W, Watson PH, Byrne JA. What Do Biomedical Researchers Want from Biobanks? Results of an Online Survey Biopreserv Biobank. 2021 Nov 9. doi: 10.1089/bio.2021.0084. Online ahead of print. PMID: 347561001. journals2021
Philipp LangeUzozie A, Ergin EK, Rolf N, Tsui J, Lorentzian A, Weng SH, Nierves L, Smith TG, Lim CJ, Maxwell C, Reid GS, LANGE PF. PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways. Journal of Experimental & Clinical Cancer Research 2021 40(96) - IF:11, Citations:5  SA
* In this work we document for the first time that the proteomes of malignant cells from patients after expansion in a mouse model are still highly equivalent to the original patient cells. This provides ciritical evidence supporting the use of patient derived mouse models in precision oncology target identification and pre-clinical studies. 
1. journals2021
Philipp LangeMateo F, He Z, Me L, Garibay GR, Herranz C, Garcia N, Lorentzian A, Baiges A, Blommaert E, GomezA, Mirallas O, Garrido-Utrilla A, Palomero L, Espin R, Extremera AI, Soler T, Petit A, Cimba, Li R, BrunetJ, Chen K, Tan SXS, Eaves CJ, McCloskey C, Hakem R, Khokha R, Lange PF, Lazaro C, Maxwell CA#, Pujana PA#. Sequential molecular and cellular alterations increase risk of BRCA1-associated triple-negative breast cancer. Nature Communications 2022, 13, 1895 CA1. journals2021
Philipp LangeErgin EK, Uzozie AC, Chen S, Su Y, LANGE PF, SQuAPP €“ Simple Quantitative Analysis of Proteins & PTMs, Bioinformatics 12/2021 under review SA1. journals2021
Philipp LangeNierves L, LANGE PF. Detectability of biotin tags by LC-MS/MS. Journal of Proteome Research. 2021, 20, 5, 3002€“3008 -IF:4, Citations:2 SA1. journals2021
Philipp LangeSmith TG, Uzozie AC, Chen S, LANGE PF, Robust unsupervised deconvolution of linear motifs characterizes 68 protein modifications at proteome scale. Scientific Reports. 2021 11(22490): 1-11. - IF:4, Citations:1 SA
 * In this work my graduate Theodore Smith student describes a major error in existing, widely used, linear motif deconvolution algorithms and develops a new algorithm overcoming the issues and advancing the scope. He then applies the newly developed algorithm to the large-scale, pan-tissue, proteome-wide analysis of sequence context of enzymatic and non-enzymatic side chain modifications of proteins. 
1. journals2021
Philipp LangeUzozie AC, Simth TG, Chen S, LANGE PF, Sensitive identification of known and unknown protease activities by unsupervised linear motif deconvolution. bioRxiv doi: 10.1101/2021.11.15.4687032021 SA1. journals2021
Philipp LangeRolf N, Liu LYT, Tsang A, LANGE PF, Lim CJ, Maxwell CA, Vercauteren SM, Reid GSD, A cross-standardized flow cytometry platform to assess phenotypic stability in precursor B-cell acute lymphoblastic leukemia (B-ALL) xenografts. CYTOMETRY PART A 2021 101 (1), 57-71 - IF:4 CA1. journals2021
Poul SorensenChiou SH, Tseng D, Reuben A, Mallajosyula V, Molina IS, Conley S, Wilhelmy J, McSween AM, Yang X, Nishimiya D, Sinha R, Nabet BY, Wang C, Shrager JB, Berry MF, Backhus L, Lui NS, Wakelee HA, Neal JW, Padda SK, Berry GJ, Delaidelli A, Sorensen PH, Sotillo E, Tran P, Benson JA, Richards R, Labanieh L, Klysz DD, Louis DM, Feldman SA, Diehn M, Weissman IL, Zhang J, Wistuba II, Futreal PA, Heymach JV, Garcia KC, Mackall CL, Davis MM. Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery. Immunity. 2021 Mar 9;54(3):586-602.e8. doi: 10.1016/j.immuni.2021.02.014. PMID: 33691136.1. journals2021
Poul SorensenSaxena N, Beraldi E, Fazli L, Somasekharan SP, Adomat H, Zhang F, Molokwu C, Gleave A, Nappi L, Nguyen K, Brar P, Nikesitch N, Wang Y, Collins C, Sorensen PH, Gleave M. Androgen Receptor (AR) antagonism triggers acute succinate-mediated adaptive responses to reactivate AR signaling. EMBO Mol Med. 2021 May 7;13(5):e13427. doi: 10.15252/emmm.202013427. PMID: 33709547.1. journals2021
Poul SorensenTurgu B, Zhang F, El-Naggar A, Negri GL, Kogler M, Tortola L, Johnson F, Ng T, Li A, Yapp D, Lockwood W, Martinez D, Maris JM, Daugaard M, Penninger JM, Hughes CS, Sorensen PH. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner. Oncogene. 2021 Feb 18. doi: 10.1038/s41388-021-01680-1. PMID: 33603169.1. journals2021
Poul SorensenPerreault S, Chami R, Deyell RJ, El Demellawy D, Ellezam B, Jabado N, Morgenstern DA, Narendran A, Sorensen PH, Wasserman JD, Yip S. Canadian Consensus for Biomarker Testing and Treatment of TRK Fusion Cancer in Pediatric Patients. Curr Oncol. 2021 Jan 9;28(1):346-366. doi: 10.3390/curroncol28010038. PMID: 33435412.1. journals2021
Poul SorensenNabbi A, Sun P, Sudhaman S, Delaidelli A, Zhu K, Yang SY, Mulder DT, Bruce JP, Paulson JN, Raman P, Zhu Y, Resnick AC, Sorensen PH, Sill M, Brabetz S, Lambo S, Johann PD, Kool M, Jones DT, Pfister SM, Jäger N, Pugh TJ. The immunogenomic landscape of primary pediatric solid tumours. In Revision, 2021.1. journals2021
Poul SorensenScopim-Ribeiro R, Lizardo MM, Zhang HF, Dhez AC, Hughes CS, Sorensen PH. NSG mice facilitate ex vivo characterization of Ewing sarcoma lung metastasis using the PuMA model. Front. Oncol. 2021 March 22;11: 645757. doi: 10.3389/fonc.2021.645757. PMID: 338289891. journals2021
Poul SorensenSipol A, Hameister E, Xue B, Hofstetter J, Barenboim M, Öllinger R, Jain G, Prexler C, Rubio RA, Baldauf MC, Franchina DG, Petry A, Schmäh J, Thiel U, Görlach A, Cario G, Brenner D, Richter G, Grünewald TGP, Rad R, Wolf E, Ruland J, Sorensen PH*, Burdach S*. MondoA Drives B-ALL Malignancy through Enhanced Adaptation to Metabolic Stress. Blood. 2021 Apr 28. doi: 10.1182/blood.2020007932. PMID: 33908607. *co-senior authors.1. journals2021
Poul SorensenDelaidelli A, Richner M, Jiang L, van der Laan A, Bergholdt Jul Christiansen I, Ferreira N, Nyengaard JR, Vægter CB, Jensen PH, Mackenzie IR, Sorensen PH, Jan A. α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response. Acta Neuropathol Commun. 2021 Jun 6;9(1):105. doi: 10.1186/s40478-021-01209-3. PMID: 34092244.1. journals2021
Poul SorensenLefort S, El-Naggar A, Tan S, Colborne S, Negri GL, Pellacani D, Hirst M, Gusterson B, Morin GB, Sorensen PH*, Eaves CJ*. De novo and cell line models of human mammary cell transformation reveal an essential role for YB-1 in multiple stages of human breast cancer. Cell Death Differ. 2021 Jul 22. doi: 10.1038/s41418-021-00836-6. PMID: 34294889. *co-senior authors1. journals2021
Poul SorensenGassmann H, Schneider K, Evdokimova V, Ruzanov P, Schober SJ, Xue B, von Heyking K, Thiede M, Richter GHS, Pfaffl MW, Noessner E, Stein LD, Sorensen PH, Burdach SEG, Thiel U. Ewing Sarcoma-Derived Extracellular Vesicles Impair Dendritic Cell Maturation and Function. Cells. 2021 Aug 13;10(8). doi: 10.3390/cells10082081. PMID: 34440851.1. journals2021
Poul SorensenZhang HF, Hughes CS, Li W, He JZ, Surdez D, El-Naggar AM, Cheng H, Prudova A, Delaidelli A, Negri GL, Li X, Orum-Madsen MS, Lizardo MM, Oso HZ, Colborne S, Shyp T, Scopim-Ribeiro R, Hammond CA, Dhez AC, Langman S, Lim JK, Kung SH, Li A, Steino A, Daugaard M, Parker SJ, Klein Geltink RI, Orentas RJ, Xu LY, Morin GB, Delattre O, Dimitrov DS, Sorensen PH. Proteomic screens for suppressors of anoikis identify IL1RAP as a promising surface target in ewing sarcoma. Cancer Discov. 2021 Nov;11(11):2884-2903. doi: 10.1158/2159-8290.CD-20-1690. PMID: 34021002.1. journals2021
Poul SorensenPachva MC, Lai H, Jia A, Rouleau M, Sorensen PH. Extracellular vesicles in reprogramming of the ewing sarcoma tumor microenvironment. Front Cell Dev Biol. 2021;9:726205. doi: 10.3389/fcell.2021.726205. PMID: PMC8484747.1. journals2021
Poul SorensenRichards RM, Zhao F, Freitas KA, Parker KR, Xu P, Fan A, Sotillo E, Daugaard M, Oo HZ, Liu J, Hong WJ, Sorensen PH, Chang HY, Satpathy AT, Majzner RG, Majeti R, Mackall CL. NOT-gated CD93 CAR T cells effectively target AML with minimized endothelial cross-reactivity. Blood Cancer Discov. 2021 Nov:2(6):648-665. doi: 10.1158/2643-3230.BCD-20-0208. PMID: 34778803.1. journals2021
Poul SorensenElisia I, Yeung M, Wong J, Kowalski S, Larsen M, Shyp T, Sorensen PH, Krystal G. A low carbohydrate diet containing soy protein and fish oil reduces breast but not prostate cancer in C3(1)/Tag mice. Carcinogenesis. 2021 Dec 27. doi: 10.1093/carcin/bgab106. PMID: 34958345.1. journals2021
Poul SorensenSomasekharan SP, Saxena N, Zhang F, Beraldi E, Huang JN, Gentle C, Fazli L, Thi M, Sorensen PH*, Gleave M*. Regulation of AR mRNA translation in response to acute AR pathway inhibition. Nucleic Acids Res. 2021 Dec 23. doi: 10.1093/nar/gkab1247. PMID: 34939643. *co-corresponding authors1. journals2021
Poul SorensenDelaidelli A, Dunham C, Santi M, Negri GL, Triscott J, Zheludkova O, Golanov A, Ryzhova M, Okonechnikov K, Schrimpf D, Stichel D, Ellison DW, von Deimling A, Kool M, Pfister SM, Ramaswamy V, Korshunov A, Taylor MD, Sorensen PH. Clinically Tractable Outcome Prediction of non-WNT/non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study. Clin Cancer Res. 2022 Jan 1;28(1). doi: 10.1158/1078-0432.CCR-21-2057. PMID: 34702771.1. journals2021
Poul SorensenHeitzeneder S, Bosse KR, Zhu Z, Zhelev D, Majzner RG, Radosevich MT, Dhingra S, Sotillo E, Buongervino S, Pascual-Pasto G, Garrigan E, Xu P, Huang J, Salzer B, Delaidelli A, Raman S, Cui H, Martinez B, Bornheimer SJ, Sahaf B, Alag A, Fetahu IS, Hasselblatt M, Parker KR, Anbunathan H, Hwang J, Huang M, Sakamoto K, Lacayo NJ, Klysz DD, Theruvath J, Vilches-Moure JG, Satpathy AT, Chang HY, Lehner M, Taschner-Mandl S, Julien JP, Sorensen PH, Dimitrov DS, Maris JM, Mackall CL. GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity. Cancer Cell. 2022 Jan 10;40(1):53-69.e9. doi: 10.1016/j.ccell.2021.12.005. PMID: 34971569.1. journals2021
Poul SorensenTheruvath J, Menard M, Smith BAH, Linde MH, Coles GL, Dalton GN, Wu W, Kiru L, Delaidelli A, Sotillo E, Silberstein JL, Geraghty AC, Banuelos A, Radosevich MT, Dhingra S, Heitzeneder S, Tousley A, Lattin J, Xu P, Huang J, Nasholm N, He A, Kuo TC, Sangalang ERB, Pons J, Barkal A, Brewer RE, Marjon KD, Vilches-Moure JG, Marshall PL, Fernandes R, Monje M, Cochran JR, Sorensen PH, Daldrup-Link HE, Weissman IL, Sage J, Majeti R, Bertozzi CR, Weiss WA, Mackall CL, Majzner RG. Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication. Nat Med. 2022 Jan 13;. doi: 10.1038/s41591-021-01625-x. PMID: 35027753.1. journals2021
Ramon GeltinkHai-Feng Zhang, Christopher S Hughes, Wei Li, Jian-Zhong He, Didier Surdez, Amal M El-Naggar, Hongwei Cheng, Anna Prudova, Alberto Delaidelli, Gian Luca Negri, Xiaojun Li, Maj Sofie Orum-Madsen, Michael M Lizardo, Htoo Zarni Oo, Shane Colborne, Taras Shyp, Renata Scopim-Ribeiro, Colin A Hammond, Anne-Chloe Dhez, Sofya Langman, Jonathan Km Lim, Sonia Hy Kung, Amy Li, Anne Steino, Mads Daugaard, Seth J Parker, RAMON I KLEIN GELTINK, Rimas J Orentas, Li-Yan Xu, Gregg B Morin, Olivier Delattre, Dimiter S Dimitrov, Poul H Sorensen. (2021). Proteomic screens for suppressors of anoikis identify IL1RAP as a promising surface target in Ewing sarcoma. Cancer Discovery. http://dx.doi.org/10.1158/2159-8290.CD-20-1690 (CA IF 39.4)1. journals2021
Ramon GeltinkDavid O'Sullivan, Michal A Stancza, Matteo Villa, Franziska M Uhl, Mauro Corrado, RAMON I KLEIN GELTINK, David E Sanin, Petya Apostolova, Nisha Rana, Joy Edwards-Hicks, Katarzyna M Grzes, Agnieszka M Kabat, Ryan L Kyle, Mario Fabri, Jonathan D Curtis, Michael D Buck, Annette E Patterson, Annamaria Regina, Cameron S Field, Francesc Baixauli, Daniel J Puleston, Edward J Pearce, Robert Zeiser, Erika L Pearce. (2021). Fever supports CD8 + effector T cell responses by promoting mitochondrial translation.Proc Natl Acad Sci USA. NA: NA. http://dx.doi.org/10.1073/pnas.2023752118 (CA IF 11.2)1. journals2021
Ramon GeltinkDivya Subburaj, Bernard Ng, Amina Kariminia, Sayeh Abdossamadi, Madeline Lauener, Eneida R. Nemecek , Jacob Rozmus, Sandhya Kharbanda, Carrie L. Kitko, Victor A. Lewis, Tal Schechter-Finklestein, David A. Jacobsohn, Andrew C. Harris, Michael A. Pulsipher, Henrique Bittencourt, Sung Won Choi, Emi H. Caywood, Kimberly A. Kasow, Monica Bhatia, Benjamin R. Oshrine, Donald Coulter, Joseph H. Chewning, Michael Joyce, Anna B. Pawlowska, Gail C. Megason, Anita Lawitschka, Elena Ostroumov, RAMON I KLEIN GELTINK, Geoffrey D.E. Cuvelier, Kirk R. Schultz. (2021). Metabolomic Identification of Alpha- Ketoglutaric Acid Elevation in Pediatric Chronic Graft- versus-Host Disease. Blood. NA: NA. http://dx.doi.org/doi: 10.1182/blood.2021013244 (CA IF 22.1)1. journals2021
Reza AlaghehbandanAlaghehbandan, R., Trpkov, K., Tretiakova, M., Luis, A.S., Rogala, J., Hes, O. Comprehensive review of numerical chromosomal aberrations in chromophobe renal cell carcinoma including its variant morphologies. Adv Anat Pathol Jan;28(1):8-20, 2021.1. journals2021
Reza AlaghehbandanKojima, F., Alaghehbandan, R., Kuroda, N., Matsuzaki, I., Mikasa, Y., Musangile, F.Y., Iwamoto, R., Takahashi, Y., Iwahashi, Y., Warigaya, K., Iba, A., Hara, I., Murata, S., Hes, O. Paneth-like cells in renal cell carcinomas and in cysts associated with acquired cystic kidney disease: Clinicopathologic analysis, comparative study and description of precursor lesions. (Ann Diagn Pathol) in press.1. journals2021
Reza AlaghehbandanVan Slyke, A.C., Roller, J.M., Alaghehbandan, R., Carr, N.J. Defining double capsules: a clinical and histological study. (Aesthet Surg J) in press.1. journals2021
Reza AlaghehbandanPitra, T., Pivovarcikova, K., Alaghehbandan, R., Compérat, E.M., Hora, M., Rogala, J., Slisarenko, M., Michal, M., Hes, O. Utility of NKX3.1 immunohistochemistry in the differential diagnosis of seminal vesicles versus prostatic tissue in needle biopsy. (Ann Diagn Pathol) in press.1. journals2021
Reza AlaghehbandanRatnam, S., Jang, D., Gilbert, L., Alaghehbandan, R., Schell, M., Needle, R., Ecobichon-Morris, A., Wang, P., Rahman, M., Costescu, D., Elit, L., Zahariadis, G., Chernesky M. CINtec PLUS and cobas HPV testing for triaging Canadian women referred to colposcopy with a history of low grade squamous intraepithelial lesion: Baseline findings. (Papillomavirus Res) in press.1. journals2021
Reza AlaghehbandanRogala, J., Kojima, F., Alaghehbandan, R., Agaimy, A., Martinek, P., Ondic, O., Ulamec, M., Sperga, M., Michalova, K., Pivovarcikova, K., Pitra, T., Hora, M., Ferak, I., Marečková, J., Michal, M., Hes, O. Papillary renal cell carcinoma with prominent spindle cell stroma - tumor mimicking mixed epithelial and stromal tumor of the kidney: Clinicopathologic, morphologic, immunohistochemical and molecular genetic analysis of 6 cases. (Ann Diagn Pathol) in press.1. journals2021
Reza AlaghehbandanMichalova, K., Tretiakova, M., Pivovarcikova, K., Alaghehbandan, R., Perez Montiel, D., Ulamec, M., Osunkoya A., Trpkov, K., Grossmann, P., Sperga, M., Ferak, I., Rogala, J., Mareckova, J., Pitra, T., Hora, M., Michal, M., Hes, O. Expanding the morphologic spectrum of chromophobe renal cell carcinoma: A study of 8 cases with papillary architecture. (Ann Diagn Pathol) in press.1. journals2021
Reza AlaghehbandanPtáková, N., Martínek, P., Holubec, L., Janovský, V., Vančurová, J., Grossmann, P., Navarro, P.A., Rodriguez Moreno, J.F., Alaghehbandan, R., Hes, O., Májek, O., Pešek, M., Michal, M., Ondič, O. Identification of tumors with NRG1 rearrangement, including a novel putative pathogenic UNC5D-NRG1 gene fusion in prostate cancer by data-drilling a de-identified tumor database. (Genes Chromosomes Cancer) in press.1. journals2021
Reza AlaghehbandanTrpkov, K., Hes, O., Williamson, S.R., Adeniran, A.J., Agaimy, A., Alaghehbandan, R., Amin, M.B., Argani, P., Chen, Y.B, Cheng, L., Epstein, J.I., Cheville, J.C., Comperat, E., Werneck da Cunha, I., Gordetsky, J.B., Gupta, S., He, H., Hirsch, M.S., Humphrey, P.A., Kapur, P., Kojima, F., Lopez, J.I., Maclean, F., Magi-Galluzzi, C., McKenney, J.K., Mehra, R., Menon, S., Netto, G.J., Przybycin, C.G., Rao, P., Rao, Q., Reuter, V.E., Saleeb, R.M., Shah, R.B., Smith, S.C., Tickoo, S., Tretiakova, M.S., True, L., Verkarre, V., Wobker, S.E., Zhou, M., Gill, A.J. New Developments in Existing WHO Entities and Evolving Molecular Concepts: The Genitourinary Pathology Society (GUPS) Update on Renal Neoplasia. (Mod Pathol) in press.1. journals2021
Reza AlaghehbandanTrpkov, K., Williamson, S.R., Gill, A.J., Adeniran, A.J., Agaimy, A., Alaghehbandan, R., Amin, M.B., Argani, P., Chen, Y.B, Cheng, L., Epstein, J.I., Cheville, J.C., Comperat, E., Werneck da Cunha, I., Gordetsky, J.B., Gupta, S., He, H., Hirsch, M.S., Humphrey, P.A., Kapur, P., Kojima, F., Lopez, J.I., Maclean, F., Magi-Galluzzi, C., McKenney, J.K., Mehra, R., Menon, S., Netto, G.J., Przybycin, C.G., Rao, P., Rao, Q., Reuter, V.E., Saleeb, R.M., Shah, R.B., Smith, S.C., Tickoo, S., Tretiakova, M.S., True, L., Verkarre, V., Wobker, S.E., Zhou, M., Hes, O. Novel, Emerging and Provisional Renal Entities: The Genitourinary Pathology Society (GUPS) Update on Renal Neoplasia. (Mod Pathol) in press.1. journals2021
Reza AlaghehbandanPivovarcikova, K., Grossmann, P., Hajkova, V., Alaghehbandan, R., Pitra, T., Perez Montiel, D., Sperga, M., Rogala, J., Slisarenko, M., Bartos Vesela, A., Svajdler, P., Michalova, K., Rotterova, P., Hora, M., Michal, M., Hes, O. Renal cell carcinomas with tubulopapillary architecture and oncocytic cells: Molecular analysis of 39 difficult tumors to classify. (Ann Diagn Pathol) in press.1. journals2021
Romina ReyesSaatchi A, Reid JN, Povitz M, Shariff SZ, Silverman M, Morris AM, Reyes RC, Patrick DM, Marra F. Appropriateness of Outpatient Antibiotic Use in Seniors across Two Canadian Provinces. Antibiotics. 2021; 10(12):1484. https://doi.org/10.3390/antibiotics101214841. journals2021
Romina ReyesAriana Saatchi, Andrew M Morris, David M Patrick, James Mccormack, Romina C Reyes, Phillip Morehouse, Jennifer Reid, Salimah Shariff, Marcus Povitz, Michael Silverman, Fawziah Marra, Outpatient antibiotic use in British Columbia, Canada: reviewing major trends since 2000, JAC-Antimicrobial Resistance, Volume 3, Issue 3, September 2021, dlab116, https://doi.org/10.1093/jacamr/dlab1161. journals2021
Ryan MorinCiara L. Freeman, Prasath Pararajalingam, Ling Jin, Sriram Balasubramanian, Aixiang Jiang, Wendan Xu, Michael Grau, Myroslav Zapukhlyak, Merrill Boyle, Brendan Hodkinson, Michael Schaffer, Christopher Enny, Sanjay Deshpande, Steven Sun, Jessica Vermeulen, Simon Rule, Ryan D. Morin, David W. Scott, and Georg Lenz. Molecular determinants of outcomes in relapsed or refractory mantle cell lymphoma treated with ibrutinib or temsirolimus in the mcl3001 (ray) trial. Leukemia, submitted1. journals2021
Ryan MorinSarah E. Arthur, Jie Gao, Shannon Healy, Christopher K. Rushton, Nicole Thomas, Laura K. Hilton, Kostiantyn Dreval, Jeffrey Tang, Miguel Alcaide, Razvan Cojocaru, Anja Mottok, Adèle Telenius, Peter Unrau, Wyndham H. Wilson, Louis M. Staudt, David W. Scott, Dan Hodson, Christian Steidl, , and Ryan D. Morin. Non-coding nfkbiz 3€² utr mutations promote cell growth and resistance to targeted therapeutics in diffuse large b-cell lymphoma. Clin Can Res, submitted1. journals2021
Ryan Morin^ * Nowicka M, * Hilton LK, Ashton-Key M, Hargreaves CE, Lee C, Foxall R, Carter MJ, Beers SA, Potter KN, Bolen CR, Klein C, Knapp A, Mir F, Rose-Zerilli M, Burton C, Klapper W, Scott DW, Sehn LH, Vitolo U, Martelli M, Trneny M, Rushton CK, Slack GW, Farinha P, Strefford JC, Oestergaard MZ, Morin RD, Cragg MS. Prognostic significance of FCGR2B expression for the response of DLBCL patients to rituximab or obinutuzumab treatment. Blood Adv. 2021 Aug 10;5(15):2945-2957. doi: 10.1182/bloodadvances.2021004770. PMID: 34323958; PMCID: PMC8361458.1. journals2021
Ryan MorinDuns G, Viganò E, Ennishi D, Sarkozy C, Hung SS, Chavez E, Takata K, Rushton C, Jiang A, Ben-Neriah S, Woolcock BW, Slack GW, Hsi ED, Craig JW, Hilton LK, Shah SP, Farinha P, Mottok A, Gascoyne RD, Morin RD, Savage KJ, Scott DW, Steidl C. Characterization of DLBCL with a PMBL gene expression signature. Blood. 2021 Jul 15;138(2):136-148. doi: 10.1182/blood.2020007683. PMID: 33684939.1. journals2021
Ryan MorinCollinge B, Ben-Neriah S, Chong L, Boyle M, Jiang A, Miyata-Takata T, Farinha P, Craig JW, Slack GW, Ennishi D, Mottok A, Meissner B, Chavez EA, Gerrie AS, Villa D, Freeman C, Savage KJ, Sehn LH, Morin RD, Mungall AJ, Gascoyne RD, Marra MA, Connors JM, Steidl C, Scott DW. The impact of MYC and BCL2 structural variants in tumors of DLBCL morphology and mechanisms of false-negative MYC IHC. Blood. 2021 Apr 22;137(16):2196-2208. doi: 10.1182/blood.2020007193. PMID: 33120427.1. journals2021
Ryan MorinMorin J, Zhang H, Royle TCA, Speller C, Alcaide M, Morin R, Yang D.  Dna-based species identification of ancient salmonid remains provides new insight into pre-contact coast salish salmon fisheries in burrard inlet, british columbia, canada. Journal of Archaeological Science: Reports, 37:102956, 20211. journals2021
Ryan MorinGebremeskel S, Schanin J, Coyle KM, Butuci M, Luu T, Brock EC, Xu A, Wong A, Leung J, Korver W, Morin RD, Schleimer RP, Bochner BS, Youngblood BA. Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody. Front Immunol. 2021 Mar 10;12:650331. doi: 10.3389/fimmu.2021.650331. PMID: 33777047; PMCID: PMC7988091.1. journals2021
Ryan MorinIsaev K, Ennishi D, Hilton L, Skinnider B, Mungall KL, Mungall AJ, Bakhtiari M, Tremblay-LeMay R, Silva A, Ben-Neriah S, Boyle M, Villa D, Marra MA, Steidl C, Gascoyne RD, Morin R, Savage KJ, Scott DW, Kridel R. Molecular attributes underlying central nervous system and systemic relapse in diffuse large B-cell lymphoma. Haematologica. 2021 May 1;106(5):1466-1471. doi: 10.3324/haematol.2020.255950. PMID: 32817292; PMCID: PMC8094129.1. journals2021
Samuel AparicioJun S-H, Toosi H, Mold J, Engblom C, Chen X, O€™Flanagan C, Hagemann-Jensen M, Sandberg R, Aparicio S, Hartman J, Roth A, Lagergren J. PhylEx: Accurate reconstruction of clonal structure via integrated analysis of bulk DNA-seq and single cell RNA-seq data. bioRxiv 2021 Feb 17.  https://doi.org/10.1101/2021.02.16.431009.1. journals2021
Samuel AparicioFunnell T*, O€™Flanagan CH*, Williams MJ, McPherson A, McKinney S, Kabeer F, Lee H, Masud T, Eirew P, Yap D, Zhang AW, Lim JLP, Wang B, Brimhall J, Biele J, Ting J, Liu YF, Beatty S, Lai D, Pham J, Grewal D, Abrams D, Havasov E, Leung S, Bojilova V, Moore RA, Rusk N, Uhlitz F, Ceglia N, Weiner AC, Douglas JM, Zamarin D, Weigelt B, Kim SH, Da Cruz Paula A, Reis-Filho JS, Li Y, Xu H, Ruiz de Algara T, Lee SR, Cerda Llanos V, IMAXT consortium, Shah SP, Aparicio S. The impact of mutational processes on structural genomic plasticity in cancer cells. bioRxiv. 2021 June 03; doi: https://doi.org/10.1101/2021.06.03.446999. * denotes equal contribution.1. journals2021
Samuel AparicioGonzález-Solares EA, Dariush A, González-Fernández C, Yoldaş A, Al Sa€™d M, Millar N, Whitmarsh T, Chornay N, Falciatori I, Fatemi A, Goodwin D, Kuett L, Mulvey C, Páez Ribes M, Qosaj F, Roth A, Vázquez-García I, Watson S, Windhager J, Aparicio S, Bodenmiller B, Boyden E, Caldas C, Harris O, Shah S, Tavaré S, CRUK IMAXT Grand Challenge Team, Bressan D, Hannon G, Walton N. The Imaging and Molecular Annotation of Xenografts and Tumours (IMAXT) High Throughput Data and Analysis Infrastructure. bioRxiv. 2021 June 22; doi: https://doi.org/10.1101/2021.06.22.448403.1. journals2021
Samuel AparicioWilliams MJ, Funnell T, O€™Flanagan CH, McPherson A, Salehi S, Vázquez-García I, Kabeer F, Lee H, Masud T, Eirew P, Yap D, Wang B, Brimhall J, Biele J, Ting J, Beatty S, Lai D, Pham J, Grewal D, Abrams D, Havasov E, Leung S, Bojilova V, Weiner AC, Rusk N, Uhlitz F, Ceglia N, IMAXT consortium, Aparicio S, Shah SP. Evolutionary tracking of cancer haplotypes at single-cell resolution. bioRxiv. 2021 June 4; doi: https://doi.org/10.1101/2021.06.04.447031. (Corresponding author). Preprints 2021.1. journals2021
Samuel AparicioMasud T, Soong C, Xu H, Biele J, Bjornson S, McKinney S, Aparicio S. Ubiquitin-mediated DNA damage response is synthetic lethal with G-quadruplex stabilizer CX-5461. Sci Rep. 2021 May 7;11(1):9812. doi: 10.1038/s41598-021-88988-w. PMID: 33963218; PMCID: PMC8105411.1. journals2021
Samuel AparicioGeorgopoulou D, Callari M, Rueda OM, Shea A, Martin A, Giovannetti A, Qosaj F, Dariush A, Chin SF, Carnevalli LS, Provenzano E, Greenwood W, Lerda G, Esmaeilishirazifard E, O'Reilly M, Serra V, Bressan D; IMAXT Consortium, Mills GB, Ali HR, Cosulich SS, Hannon GJ, Bruna A, Caldas C. Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response. Nat Commun. 2021 Mar 31;12(1):1998. doi: 10.1038/s41467-021-22303-z. PMID: 33790302; PMCID: PMC8012607.1. journals2021
Samuel AparicioAlon S, Goodwin DR, Sinha A, Wassie AT, Chen F, Daugharthy ER, Bando Y, Kajita A, Xue AG, Marrett K, Prior R, Cui Y, Payne AC, Yao CC, Suk HJ, Wang R, Yu CJ, Tillberg P, Reginato P, Pak N, Liu S, Punthambaker S, Iyer EPR, Kohman RE, Miller JA, Lein ES, Lako A, Cullen N, Rodig S, Helvie K, Abravanel DL, Wagle N, Johnson BE, Klughammer J, Slyper M, Waldman J, Jané-Valbuena J, Rozenblatt-Rosen O, Regev A; IMAXT Consortium, Church GM, Marblestone AH, Boyden ES. Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems. Science. 2021 Jan 29;371(6528):eaax2656. doi: 10.1126/science.aax2656. PMID: 33509999; PMCID: PMC7900882.1. journals2021
Samuel AparicioDentro SC, Leshchiner I, Haase K, Tarabichi M, Wintersinger J, Deshwar AG, Yu K, Rubanova Y, Macintyre G, Demeulemeester J, Vázquez-García I, Kleinheinz K, Livitz DG, Malikic S, Donmez N, Sengupta S, Anur P, Jolly C, Cmero M, Rosebrock D, Schumacher SE, Fan Y, Fittall M, Drews RM, Yao X, Watkins TBK, Lee J, Schlesner M, Zhu H, Adams DJ, McGranahan N, Swanton C, Getz G, Boutros PC, Imielinski M, Beroukhim R, Sahinalp SC, Ji Y, Peifer M, Martincorena I, Markowetz F, Mustonen V, Yuan K, Gerstung M, Spellman PT, Wang W, Morris QD, Wedge DC, Van Loo P; PCAWG Evolution and Heterogeneity Working Group and the PCAWG Consortium. Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes. Cell. 2021 Apr 15;184(8):2239-2254.e39. doi: 10.1016/j.cell.2021.03.009. Epub 2021 Apr 7. PMID: 33831375; PMCID: PMC8054914.1. journals2021
Samuel AparicioSalehi S*, Kabeer F*, Ceglia N, Andronescu M, Williams MJ, Campbell KR, Masud T, Wang B, Biele J, Brimhall J, Gee D, Lee H, Ting J, Zhang AW, Tran H, O'Flanagan C, Dorri F, Rusk N, de Algara TR, Lee SR, Cheng BYC, Eirew P, Kono T, Pham J, Grewal D, Lai D, Moore R, Mungall AJ, Marra MA; IMAXT Consortium, McPherson A, Bouchard-Côté A, Aparicio S, Shah SP. Clonal fitness inferred from time-series modelling of single-cell cancer genomes. Nature. 2021 Jul;595(7868):585-590. doi: 10.1038/s41586-021-03648-3. Epub 2021 Jun 23. PMID: 34163070; PMCID: PMC8396073. * denotes equal contribution.1. journals2021
Samuel AparicioBatra RN, Lifshitz A, Vidakovic AT, Chin SF, Sati-Batra A, Sammut SJ, Provenzano E, Ali HR, Dariush A, Bruna A, Murphy L, Purushotham A, Ellis I, Green A, Garrett-Bakelman FE, Mason C, Melnick A, Aparicio SAJR, Rueda OM, Tanay A, Caldas C. DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation. Nat Commun. 2021 Sep 13;12(1):5406. doi: 10.1038/s41467-021-25661-w. PMID: 34518533; PMCID: PMC8437946.1. journals2021
Samuel AparicioHaile S, Corbett RD, LeBlanc VG, Wei L, Pleasance S, Bilobram S, Nip KM, Brown K, Trinh E, Smith J, Trinh DL, Bala M, Chuah E, Coope RJN, Moore RA, Mungall AJ, Mungall KL, Zhao Y, Hirst M, Aparicio S, Birol I, Jones SJM, Marra MA. A Scalable Strand-Specific Protocol Enabling Full-Length Total RNA Sequencing From Single Cells. Front Genet. 2021 Jun 3;12:665888. doi: 10.3389/fgene.2021.665888. PMID: 34149808; PMCID: PMC8209500.1. journals2021
Samuel AparicioOhori M, Nakayama Y, Ogasawara-Shimizu M, Toyoshiba H, Nakanishi A, Aparicio S, Araki S. Gene regulatory network analysis defines transcriptome landscape with alternative splicing of human umbilical vein endothelial cells during replicative senescence. BMC Genomics. 2021 Dec 2;22(1):869. doi: 10.1186/s12864-021-08185-x. PMID: 34856941; PMCID: PMC8641155.1. journals2021
Samuel AparicioBressan D, Mulvey CM, Qosaj F, Becker R, Grimaldi F, Coffey S, Vogl SL, Kuett L, Catena R, Dariush A, Gonzalez-Fernandez C, Gonzalez-Solares EA, AI Sa€™d M, Yoldaş A, Whitmarsh T, Falciatori I,  Watson SS, CRUK IMAXT Grand Challenge Team, Joyce JA, Walton N,  Bodenmiller B, Harris O, Hannon GJ. Exploration and analysis of molecularly annotated, 3D models of breast cancer at single-cell resolution using virtual reality. bioRxiv. 2021 June 29. Doi: https://doi.org/10.1101/2021.06.28.448342.1. journals2021
Shannon RussellSmith, C. R., Enns, C., Cutfeet, D., Alfred, S., James, N., Lindbeck, J., Russell, S. L. COVID-19 in a remote First Nations community in Canada: An Outbreak Summary. CMAJ. Accepted Nov. 30, 2021. E1073.1. journals2021
Shazia MasudPyelonephritis and Bacteremia Caused by Klebsiella variicola following Renal Transplantation1. journals2021
Shazia MasudCOVID-19 in an Immunocompromised Host: Persistent Shedding of Viable SARS-CoV-2 and Emergence of Multiple Mutations, a Case Report1. journals2021
Shazia MasudSARS-CoV-2 Serology: Validation of High-Throughput Chemiluminescent Immunoassay (CLIA) Platforms and a Field Study in British Columbia1. journals2021
Sohrab Shah Chow A, Schad S, Green MD, Hellmann MD, Allaj V, Ceglia N, Zago G, Shah NS, Sharma SK, Mattar M, Chan J, Rizvi H, Zhong H, Liu C, Bykov Y, Zamarin D, Shi H, Budhu S, Wohlhieter C, Uddin F, Gupta A, Khodos I, Waninger JJ, Qin A, Markowitz GJ, Mittal V, Balachandran V, Durham JN, Le DT, Zou W, Shah SP, McPherson A, Panageas K, Lewis JS, Perry JSA, de Stanchina E, Sen T, Poirier JT, Wolchok JD, Rudin CM, Merghoub T. Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity. Cancer Cell. 2021 Jul 12;39(7):973-988.e9. doi: 10.1016/j.ccell.2021.05.006. Epub 2021 Jun 10. PMID: 34115989.1. journals2021
Sohrab Shah Salehi S, Kabeer F, Ceglia N, Andronescu M, Williams MJ, Campbell KR, Masud T, Wang B, Biele J, Brimhall J, Gee D, Lee H, Ting J, Zhang AW, Tran H, O'Flanagan C, Dorri F, Rusk N, de Algara TR, Lee SR, Cheng BYC, Eirew P, Kono T, Pham J, Grewal D, Lai D, Moore R, Mungall AJ, Marra MA; IMAXT Consortium, McPherson A, Bouchard-Côté A, Aparicio S, Shah SP. Clonal fitness inferred from time-series modelling of single-cell cancer genomes. Nature. 2021 Jul;595(7868):585-590. doi: 10.1038/s41586-021-03648-3. Epub 2021 Jun 23. PMID: 34163070.1. journals2021
Sohrab ShahAoki T, Chong LC, Takata K, Milne K, Marshall A, Chavez EA, Miyata-Takata T, Ben-Neriah S, Unrau D, Telenius A, Boyle M, Weng AP, Savage KJ, Scott DW, Farinha P, Shah SP, Nelson BH, Steidl C. Single-cell profiling reveals the importance of CXCL13/CXCR5 axis biology in lymphocyte-rich classic Hodgkin lymphoma. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2105822118. doi: 10.1073/pnas.2105822118. PMID: 34615710; PMCID: PMC8521678.1. journals2021
Sohrab ShahDuns G, Viganò E, Ennishi D, Sarkozy C, Hung SS, Chavez E, Takata K, Rushton C, Jiang A, Ben-Neriah S, Woolcock BW, Slack GW, Hsi ED, Craig JW, Hilton LK, Shah SP, Farinha P, Mottok A, Gascoyne RD, Morin RD, Savage KJ, Scott DW, Steidl C. Characterization of DLBCL with a PMBL gene expression signature. Blood. 2021 Jul 15;138(2):136-148. doi: 10.1182/blood.2020007683. PMID: 33684939.1. journals2021
Sohrab ShahMaura F, Diamond B, Maclachlan KH, Derkach A, Yellapantula VD, Rustad EH, Hultcrantz M, Shah UA, Hong J, Landau HJ, Iacobuzio-Donahue CA, Papaemmanuil E, Irby S, Crowley L, Crane M, Webber MP, Goldfarb DG, Zeig-Owens R, Giricz O, Verma A, Prezant DJ, Dogan A, Shah SP, Zhang Y, Landgren O. Initial Whole-Genome Sequencing of Plasma Cell Neoplasms in First Responders and Recovery Workers Exposed to the World Trade Center Attack of September 11, 2001. Clin Cancer Res. 2021 Apr 1;27(7):2111-2118. doi: 10.1158/1078-0432.CCR-20-2245. Epub 2021 Jan 27. PMID: 33504553; PMCID: PMC8026670.1. journals2021
Sohrab ShahRashid S, Shah S, Bar-Joseph Z, Pandya R. Dhaka: Variational Autoencoder for Unmasking Tumor Heterogeneity from Single Cell Genomic Data. Bioinformatics. 2021 June 1:btz095. doi: 10.1093/bioinformatics/btz095. Epub ahead of print. PMID: 30768159.1. journals2021
Steven WhiteWebster G, Puckelwartz MJ, Pesce LL, Dellefave-Castillo LM, Vanoye CG, Potet F, Page P, Kearns SD, Pottinger T, White S, Arunkumar P, Olson R, Kofman A, Ibrahim N, Ing A, Brew C, Yap KL, Kadri S, George AL, McNally EM. Genomic autopsy of 103 sudden deaths in the young demonstrates monogenic and oligogenic risk. Journal of the American Medical Association (JAMA) Cardiology, 2021; 6 (11): 1247-1256; doi:10.1001/jamacardio.2021.2789.1. journals2021
Steven WhiteSerenelli S, White S, Arunkumar P, Gitto L. Deaths due to cardiomyopathy of unknown etiology in children and young adults. Current Forensic Science, 2021; in press.1. journals2021
Sukhbir KaurTaher J, Randell EW, Arnoldo S, Bailey D, De Guire V, Kaur S, Knauer M, Petryayeva E, Poutanen SM, Shaw JLV, Uddayasankar U, White-Al Habeeb N, Konforte D. Canadian Society of Clinical Chemists (CSCC) consensus guidance for testing, selection and quality management of SARS-CoV-2 point-of-care tests. Clin Biochem. 2021 Sep;95:1-12. doi: 10.1016/j.clinbiochem.2021.05.010. Epub 2021 May 25. PMID: 34048776; PMCID: PMC8144094.1. journals2021
Suzanne VercauterenDavid Carpentieri, Daniel Catchpoole, and Suzanne Vercauteren. (2021) Special Issue on Biobanking for Pediatric Research. Biopreservation and Biobanking. Published Online: 26 Mar 2021 https://doi.org/10.1089/bio.2021.29083.djc1. journals2021
Suzanne VercauterenAl Moosawi M, Vercauteren S. Cerebrospinal fluid with unusual natural killer cell population.  Blood. 2021 Jan 14;137(2):281. doi: 10.1182/blood.2020007789.1. journals2021
Suzanne VercauterenKong MC, Shih J, Tarling TE, Kong CC, van Tassel H, Dittrick M, Vercauteren SM. Biobank Awareness Changes Opinions of Adolescents and Parents on Participation and Practices. Biopreserv Biobank. 2021 Jul 28. doi: 10.1089/bio.2020.0157. Epub ahead of print. PMID: 34319789.1. journals2021
Suzanne VercauterenTamsin E Tarling, Veronica Chow, Ashton Ellis, Adam Velenosi and Suzanne M Vercauteren. Ethical Challenges for Pediatric Biobanks. Bioprervation and Biobanking. Special edition Biobanking and Biopreservation April 2021.1. journals2021
Suzanne VercauterenDiagnosis of chronic granulomatous disease with dihydrorhodamine 123 flow cytometry assay using different reporting methods. Zi Yi Shen, Suzanne Vercauteren, Lorraine Liu, Nicholas Au. Submitted1. journals2021
Suzanne VercauterenPei LX, Kroeun H, Vercauteren SM, Barr SI, Green TJ, Albert AY, Karakochuk CD. Baseline Hemoglobin, Hepcidin, Ferritin, and Total Body Iron Stores are Equally Strong Diagnostic Predictors of a Hemoglobin Response to 12 Weeks of Daily Iron Supplementation in Cambodian Women. J Nutr. 2021 Aug 7;151(8):2255-2263. doi: 10.1093/jn/nxab108. PMID: 33978187; PMCID: PMC8349118.1. journals2021
Suzanne VercauterenWilliams BA, Mayer C, McCartney H, Devlin AM, Lamers Y, Vercauteren SM, Wu JK, Karakochuk CD. Detectable Unmetabolized Folic Acid and Elevated Folate Concentrations in Folic Acid-Supplemented Canadian Children With Sickle Cell Disease. Front Nutr. 2021 Apr 21;8:642306. doi: 10.3389/fnut.2021.642306. eCollection 2021. PMID: 33968971 Free PMC article.1. journals2021
Suzanne VercauterenEnok Bonong PR, Buteau C, Duval M, Lacroix J, Laporte L, Tucci M, Robitaille N, Spinella PC, Cuvelier GDE, Lewis V, Vercauteren S, Alfieri C, Trottier H. Risk factors for post-transplant Epstein-Barr virus events in pediatric recipients of hematopoietic stem cell transplants. Pediatr Transplant. 2021 Jun 2:e14052. doi: 10.1111/petr.14052. Online ahead of print. PMID: 340769391. journals2021
Suzanne VercauterenMatzke LA, Tarling TE, Gali B, Dee S, LeBlanc J, Vercauteren S, Watson PH. Finding the Value in Biobanks: Enhancing the CTRNet Locator. Biopreserv Biobank. 2021 Jul 12. doi: 10.1089/bio.2021.0043. Epub ahead of print. PMID: 34252293.1. journals2021
Suzanne VercauterenDiop NS, Enok Bonong PR, Buteau C, Duval M, Lacroix J, Laporte L, Tucci M, Robitaille N, Spinella PC, Cuvelier G, Vercauteren SM, Lewis V, Alfieri C, Trottier H. Association between Antiviral Prophylaxis and Cytomegalovirus and Epstein-Barr Virus DNAemia in Pediatric Recipients of Allogeneic Hematopoietic Stem Cell Transplant. Vaccines (Basel). 2021 Jun 7;9(6):610. doi: 10.3390/vaccines9060610. PMID: 34200239; PMCID: PMC8226807.1. journals2021
Torsten NielsenMelanie Spears, Elizabeth N. Kornaga, Nicola Lyttle, Linda Liao, Jane Bayani, Mary-Anne Quintayo, Cindy Q Yao, Alister D€™Costa, Paul C Boutros, Chris Twelves, Kathleen I Pritchard, Mark N. Levine, Torsten O Nielsen, Lois Shepherd, John M.S. Bartlett. A Histone gene signature predicts anthracycline response in early breast cancer. Provisionally accepted at  JCO Precision Oncology (2nd round of revisions underway, August 2021)1. journals2021
Torsten NielsenXue Qi Wang, Angela Goytain, Brendan Dickson, Torsten Owen Nielsen. Advances in sarcoma molecular diagnostics. Provisionally accepted at Genes Chromosomes and Cancer  (November 2021).1. journals2021
Torsten NielsenKarama Asleh, Gian L. Negri, Sandra E. Spencer Miko, Shane Colborne, Christopher S. Hughes, Xiu Q. Wang, Doris Gao, C. Blake Gilks, Stephen K.L. Chia, Torsten O. Nielsen, Gregg B. Morin. Proteomic analysis of breast cancer clinical specimens identifies biological subtypes with distinct survival outcomes. In press at Nature Communications  (December 2021).1. journals2021
Torsten NielsenTorsten O. Nielsen, Samuel C.Y. Leung , David L. Rimm, Andrew Dodson, Balazs Acs, Sunil Badve, Carsten Denkert, Matthew J. Ellis, Susan Fineberg, Margaret Flowers, Hans H. Kreipe, Anne-Vibeke Laenkholm, Hongchao Pan, Frédérique M. Penault-Llorca, Mei-Yin Polley, Roberto Salgado, Ian E. Smith, Tomoharu Sugie, John M.S. Bartlett, Lisa M. McShane, Mitch Dowsett, Daniel F. Hayes. Assessment of Ki67 in Breast Cancer: Updated Recommendations from the International Ki67 in Breast Cancer Working Group. JNCI Journal of the National Cancer Institute  Volume 113, Issue 7, July 2021, Pages 808€“819, https://doi.org/10.1093/jnci/djaa201. Contribution: 20%. Lead author for international group. [published correpondance and reply in  J Natl Cancer Inst. Volume 113, Issue 11, November 2021, Pages 1597€“1598, doi: 10.1093/jnci/djab094].1. journals2021
Torsten NielsenXiu Qing Wang, Xue Qi Wang, Anika T. Ye Way Hsu, Angela Goytain, Tony L Tin Ng, Torsten O. Nielsen. A rapid and cost-effective gene expression assay for the diagnosis of well differentiated and dedifferentiated liposarcomas. Journal of Molecular Diagnostics  2021 Mar;23(3):274-284. Contribution: 33%. Initiated and directed study, supervised 1st three authors. [This article was a subject of a press release issued by the publisher: https://www.elsevier.com/about/press-releases/research-and-journals/new-test-provides-fast-and-accurate-diagnosis-of-liposarcomas].1. journals2021
Torsten NielsenMei-Yin C. Polley, Roberto A. Leon-Ferre, Samuel Leung, Angela Cheng, Dongxia Gao, Jason Sinnwell, Heshan Liu, David W. Hillman, Abraham Eyman-Casey, Judith A. Gilbert, Vivian Negron, Judy C. Boughey, Minetta C. Liu, James N. Ingle, Krishna Kalari, Fergus Couch, Jodi M. Carter, Daniel W. Visscher, Torsten O. Nielsen, Matthew P. Goetz. A clinical calculator to predict disease outcomes in women with triple-negative breast cancer. Breast Cancer Research and Treatment  2021 Feb;185(3):557-566. Contribution: 5%. Arranged access to most of the required data, edited manuscript.1. journals2021
Torsten NielsenShawn C Chafe, Nazia Riaz, Samantha Burugu, Dongxia Gao, Samuel Leung, Anna Lee, Cheng Han Lee, Shoukat Dedhar, Torsten O Nielsen. G-CSF expression in breast cancer and its association with carbonic anhydrase IX and immune checkpoints. Cancers  2021; 13(5):1022. https://doi.org/10.3390/cancers13051022. Contribution: 20% (coordinated data collection, collaborative efforts, manuscript writing).1. journals2021
Torsten NielsenElisabeth S Stovgaard, Karama Asleh, Nazia Riaz, Samuel Leung, Dongxia Gao, Lise B Nielsen, Anne-Vibeke Lænkholm, Eva Balslev, Mai-Britt R Jensen, Dorte Nielsen, Torsten O Nielsen. The immune microenvironment and relation to clinical outcomes in advanced breast cancer patients treated with docetaxel with or without gemcitabine. OncoImmunology  2021 May 11;10(1):1924492. Contribution: 30%. Conceived, organized and helped execute study and writeup; supervised 1st five authors.1. journals2021
Torsten NielsenKarama Asleh, Nazia Riaz, Angela S. Cheng, Dongxia Gao, Samuel C. Y. Leung, Meenakshi Anurag, Torsten O. Nielsen. Proteomics-derived basal biomarker DNA-PKcs is associated with intrinsic subtype and long-term clinical outcomes in breast cancer.  npj Breast Cancer 2021 Sep 9;7(1):114. doi: 10.1038/s41523-021-00320-x. Contribution: 25%. Directed study and supervised 5 authors.1. journals2021
Torsten NielsenKarama Asleh, Dongsheng Tu, Dongxia Gao, Vivien Bramwell, Mark N. Levine, Kathleen I. Pritchard, Lois E. Shepherd, Torsten O. Nielsen. Predictive significance of an optimized immunohistochemical panel for basal-like breast cancer: Results from the Canadian Cancer Trials Group CCTG MA.5 and CCTG MA.12 phase III clinical trials. Clinical Cancer Research  2021 Dec; 27: 6570-6579. Contribution: 30%. Conceived, activated and organized study; supervised 1st author1. journals2021
Torsten NielsenKristina-Ana Klaric, Nazia Riaz, Karama Asleh, Xiu Qing Wang, Tadros Atalla, Sarah Strickland, Torsten O. Nielsen, Zuzana Kos. SRY-box transcription factor 10 is a highly specific biomarker of basal-like breast cancer. Histopathology  2021 Nov 1. doi: 10.1111/his.14592. Online ahead of print. PMID: 34725848. Contribution 15%. Designed half of the study and edited manuscript.1. journals2021
Torsten NielsenNazia Riaz, Samantha Burugu, Angela S. Cheng, Samuel C.Y Leung, Dongxia Gao, Torsten O Nielsen. Prognostic significance of CSF-1R expression in early invasive breast cancer. Cancers  2021, 13, 5769. https://doi.org/10.3390/cancers13225769. Contribution: 25%. Supervised 1st author; coordinated, helped design and implement study.1. journals2021
Tracy TuckerCheung CC, Smith AC, Albadine R, Bigras G, Bojarski A, Couture C, Cutz JC, Huang WY, Ionescu D, Itani D, Izevbaye I, Karsan A, Kelly MM, Knoll J, Kwan K, Nasr MR, Qing G, Rashid-Kolvear F, Sekhon HS, Spatz A, Stockley T, Tran-Thanh D, Tucker T, Waghray R, Wang H, Xu Z, Yatabe Y, Torlakovic EE, Tsao MS. Canadian ROS proto-oncogene 1 study (CROS) for multi-institutional implementation of ROS1 testing in non-small cell lung cancer.  Lung Cancer. 2021 160:127-135.1. journals2021
Tracy TuckerDixon K, Asrat MJ, Bedard AC, Binnington K, Compton K, Cremin C, Heidary N, Lohn Z, Lovick N, McCullum M, Mindlin A, O'Loughlin M, Petersen T, Portigal-Todd C, Scott J, St-Martin G, Thompson J, Turnbull R, Mung SW, Hong Q, Bezeau M, Bosdet I, Tucker T, Young S, Yip S, Aubertin G, Blood KA, Nuk J, Sun S, Schrader KA.  Integrating Tumor Sequencing Into Clinical Practice for Patients With Mismatch Repair-Deficient Lynch Syndrome Spectrum Cancers. Clin Transl Gastroenterol. 2021 16;12(8)1. journals2021
Tracy TuckerWang G, Xiong W, Tucker T, Tran H, Nappi L, Yuan R. Primary pure carcinoid tumor of the testis: Radiology, pathology and molecular correlation. Urol Case Rep. 2021 21;39:101787.1. journals2021
Tracy TuckerMighton C, Smith AC, Mayers J, Tomaszewski R, Taylor S, Hume S, Agatep R, Spriggs E, Feilotter HE, Semenuk L, Wong H, Lazo de la Vega L, Marshall CR, Axford MM, Silver T, Charames GS, Di Gioacchino V, Watkins N, Foulkes WD, Clavier M, Hamel N, Chong G, Lamont RE, Parboosingh J, Karsan A, Bosdet I, Young SS, Tucker T, Akbari MR, Speevak MD, Vaags AK, Lebo MS, Lerner-Ellis J; Canadian Open Genetics Repository Working Group. Data sharing to improve concordance in variant interpretation across laboratories: results from the Canadian Open Genetics Repository. J Med Genet. 2021 Apr 19.1. journals2021
Valery LavergneGhannoum M, Berling I, Lavergne V, Roberts DM, Galvao T, Hoffman RS, Nolin TD, Lewington A, Doi K, Gosselin S. Recommendations from the EXTRIP workgroup on extracorporeal treatment for baclofen poisoning. Kidney Int. 2021 Aug 4:S0085-2538(21)00733-X. doi: 10.1016/j.kint.2021.07.014. Epub ahead of print. PMID: 34358487.1. journals2021
Valery LavergneWoods CR, Bradley JS, Chatterjee A, Copley LA, Robinson J, Kronman MP, Arrieta A, Fowler SL, Harrison C, Carrillo-Marquez MA, Arnold SR, Eppes SC, Stadler LP, Allen CH, Mazur LJ, Creech CB, Shah SS, Zaoutis T, Feldman DS, Lavergne V. Clinical Practice Guideline by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America: 2021 Guideline on Diagnosis and Management of Acute Hematogenous Osteomyelitis in Pediatrics. J Pediatric Infect Dis Soc. 2021 Aug 5:piab027. doi: 10.1093/jpids/piab027. Epub ahead of print. PMID: 34350458.1. journals2021
Valery LavergneJohnson S, Lavergne V, Skinner AM, Gonzales-Luna AJ, Garey KW, Kelly CP, Wilcox MH. Clinical Practice Guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults. Clin Infect Dis. 2021 Jun 24:ciab549. doi: 10.1093/cid/ciab549. Epub ahead of print. PMID: 34164674.1. journals2021
Valery LavergneHanson KE, Altayar O, Caliendo AM, Arias CA, Englund JA, Hayden MK, Lee MJ, Loeb M, Patel R, El Alayli A, Sultan S, Falck-Ytter Y, Lavergne V, Mansour R, Morgan RL, Murad MH, Patel P, Bhimraj A, Mustafa RA. The Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19: Antigen Testing. Clin Infect Dis. 2021 Jun 23:ciab557. doi: 10.1093/cid/ciab557. Epub ahead of print. PMID: 34160592.1. journals2021
Valery LavergneHanson KE, Altayar O, Caliendo AM, Arias CA, Englund JA, Hayden MK, Lee MJ, Loeb M, Patel R, El Alayli A, Sultan S, Falck-Ytter Y, Lavergne V, Mansour R, Morgan RL, Murad MH, Patel P, Bhimraj A, Mustafa RA. The Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19: Antigen Testing. Clin Infect Dis. 2021 Jun 23:ciab557. doi: 10.1093/cid/ciab557. Epub ahead of print. PMID: 34160592.1. journals2021
Valery LavergneBouchard J, Shepherd G, Hoffman RS, Gosselin S, Roberts DM, Li Y, Nolin TD, Lavergne V, Ghannoum M; EXTRIP workgroup. Extracorporeal treatment for poisoning to beta-adrenergic antagonists: systematic review and recommendations from the EXTRIP workgroup. Crit Care. 2021 Jun 10;25(1):201. doi: 10.1186/s13054-021-03585-7. PMID: 34112223; PMCID: PMC8194226.1. journals2021
Valery LavergneMowry JB, Shepherd G, Hoffman RS, Lavergne V, Gosselin S, Nolin TD, Vijayan A, Kielstein JT, Roberts DM, Ghannoum M; Extracorporeal Treatments in Poisoning workgroup. Extracorporeal treatments for isoniazid poisoning: Systematic review and recommendations from the EXTRIP workgroup. Pharmacotherapy. 2021 May;41(5):463-478. doi: 10.1002/phar.2519. Epub 2021 Apr 3. PMID: 33660266.1. journals2021
Valery LavergneHuttner A, Bricheux A, Buurmeijer-van Dijk CJM, Harvey M, Holmes A, Lassmann B, Lavergne V, Mailles A, Mendelson M, Muller N, Sanguinetti M, Sears C, Skevaki C, Syed U, Thomas S, Swartz TH; European Society of Clinical Microbiology and Infectious Diseases; Federation of European Microbiological Societies; Infectious Disease Society of America; International Society for Infectious Diseases; Swiss Society for Infectious Diseases. Joint ESCMID, FEMS, IDSA, ISID and SSI position paper on the fair handling of career breaks among physicians and scientists when assessing eligibility for early-career awards. Clin Microbiol Infect. 2021 Feb 18:S1198-743X(21)00056-2. doi: 10.1016/j.cmi.2021.01.029. Epub ahead of print. PMID: 33609786.1. journals2021
Valery LavergneWong A, Hoffman RS, Walsh SJ, Roberts DM, Gosselin S, Bunchman TE, Kebede S, Lavergne V, Ghannoum M; EXTRIP workgroup. Extracorporeal treatment for calcium channel blocker poisoning: systematic review and recommendations from the EXTRIP workgroup. Clin Toxicol (Phila). 2021 May;59(5):361-375. doi: 10.1080/15563650.2020.1870123. Epub 2021 Feb 8. PMID: 33555964.1. journals2021
Valery LavergneEckbo EJ, Locher K, Caza M, Li L, Lavergne V, Charles M. Evaluation of the BioFire® COVID-19 test and Respiratory Panel 2.1 for rapid identification of SARS-CoV-2 in nasopharyngeal swab samples. Diagn Microbiol Infect Dis. 2021 Mar;99(3):115260. doi: 10.1016/j.diagmicrobio.2020.115260. Epub 2020 Nov 10. PMID: 33340934; PMCID: PMC7654322.1. journals2021
Valery LavergneKrause PJ, Auwaerter PG, Bannuru RR, Branda JA, Falck-Ytter YT, Lantos PM, Lavergne V, Meissner HC, Osani MC, Rips JG, Sood SK, Vannier E, Vaysbrot EE, Wormser GP. Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA): 2020 Guideline on Diagnosis and Management of Babesiosis. Clin Infect Dis. 2021 Jan 27;72(2):185-189. doi: 10.1093/cid/ciab050. PMID: 33501959.1. journals2021
Valery LavergneLantos PM, Rumbaugh J, Bockenstedt LK, Falck-Ytter YT, Aguero-Rosenfeld ME, Auwaerter PG, Baldwin K, Bannuru RR, Belani KK, Bowie WR, Branda JA, Clifford DB, DiMario FJ, Halperin JJ, Krause PJ, Lavergne V, Liang MH, Meissner HC, Nigrovic LE, Nocton JJJ, Osani MC, Pruitt AA, Rips J, Rosenfeld LE, Savoy ML, Sood SK, Steere AC, Strle F, Sundel R, Tsao J, Vaysbrot EE, Wormser GP, Zemel LS. Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease. Clin Infect Dis. 2021 Jan 23;72(1):1-8. doi: 10.1093/cid/ciab049. PMID: 33483734.1. journals2021
Valery LavergneHanson KE, Caliendo AM, Arias CA, Hayden MK, Englund JA, Lee MJ, Loeb M, Patel R, El Alayli A, Altayar O, Patel P, Falck-Ytter Y, Lavergne V, Morgan RL, Murad MH, Sultan S, Bhimraj A, Mustafa RA. The Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19: Molecular Diagnostic Testing. Clin Infect Dis. 2021 Jan 22:ciab048. doi: 10.1093/cid/ciab048. Epub ahead of print. PMID: 33480973; PMCID: PMC7929045.1. journals2021
Valery LavergneLantos PM, Rumbaugh J, Bockenstedt LK, Falck-Ytter YT, Aguero-Rosenfeld ME, Auwaerter PG, Baldwin K, Bannuru RR, Belani KK, Bowie WR, Branda JA, Clifford DB, DiMario FJ, Halperin JJ, Krause PJ, Lavergne V, Liang MH, Meissner HC, Nigrovic LE, Nocton JJJ, Osani MC, Pruitt AA, Rips J, Rosenfeld LE, Savoy ML, Sood SK, Steere AC, Strle F, Sundel R, Tsao J, Vaysbrot EE, Wormser GP, Zemel LS. Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease. Clin Infect Dis. 2021 Jan 23;72(1):e1-e48. doi: 10.1093/cid/ciaa1215. PMID: 33417672.1. journals2021
Valery LavergneLantos PM, Rumbaugh J, Bockenstedt LK, Falck-Ytter YT, Aguero-Rosenfeld ME, Auwaerter PG, Baldwin K, Bannuru RR, Belani KK, Bowie WR, Branda JA, Clifford DB, DiMario FJ Jr, Halperin JJ, Krause PJ, Lavergne V, Liang MH, Meissner HC, Nigrovic LE, Nocton JJJ, Osani MC, Pruitt AA, Rips J, Rosenfeld LE, Savoy ML, Sood SK, Steere AC, Strle F, Sundel R, Tsao J, Vaysbrot EE, Wormser GP, Zemel LS. Clinical Practice Guidelines by the Infectious Diseases Society of America, American Academy of Neurology, and American College of Rheumatology: 2020 Guidelines for the Prevention, Diagnosis, and Treatment of Lyme Disease. Neurology. 2021 Feb 9;96(6):262-273. doi: 10.1212/WNL.0000000000011151. Epub 2020 Nov 30. Erratum in: Neurology. 2021 Feb 9;96(6):296. PMID: 33257476.1. journals2021
Valery LavergneKrause PJ, Auwaerter PG, Bannuru RR, Branda JA, Falck-Ytter YT, Lantos PM, Lavergne V, Meissner HC, Osani MC, Rips JG, Sood SK, Vannier E, Vaysbrot EE, Wormser GP. Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA): 2020 Guideline on Diagnosis and Management of Babesiosis. Clin Infect Dis. 2021 Jan 27;72(2):e49-e64. doi: 10.1093/cid/ciaa1216. Erratum in: Clin Infect Dis. 2021 Jul 1;73(1):172-173. PMID: 33252652.1. journals2021
Valery LavergneLantos PM, Rumbaugh J, Bockenstedt LK, Falck-Ytter YT, Aguero-Rosenfeld ME, Auwaerter PG, Baldwin K, Bannuru RR, Belani KK, Bowie WR, Branda JA, Clifford DB, DiMario FJ Jr, Halperin JJ, Krause PJ, Lavergne V, Liang MH, Cody Meissner H, Nigrovic LE, Nocton JJJ, Osani MC, Pruitt AA, Rips J, Rosenfeld LE, Savoy ML, Sood SK, Steere AC, Strle F, Sundel R, Tsao J, Vaysbrot EE, Wormser GP, Zemel LS. Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis, and Treatment of Lyme Disease. Arthritis Rheumatol. 2021 Jan;73(1):12-20. doi: 10.1002/art.41562. Epub 2020 Nov 29. PMID: 33251716.1. journals2021
Valery LavergneLantos PM, Rumbaugh J, Bockenstedt LK, Falck-Ytter YT, Aguero-Rosenfeld ME, Auwaerter PG, Baldwin K, Bannuru RR, Belani KK, Bowie WR, Branda JA, Clifford DB, DiMario FJ Jr, Halperin JJ, Krause PJ, Lavergne V, Liang MH, Cody Meissner H, Nigrovic LE, Nocton JJJ, Osani MC, Pruitt AA, Rips J, Rosenfeld LE, Savoy ML, Sood SK, Steere AC, Strle F, Sundel R, Tsao J, Vaysbrot EE, Wormser GP, Zemel LS. Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis, and Treatment of Lyme Disease. Arthritis Care Res (Hoboken). 2021 Jan;73(1):1-9. doi: 10.1002/acr.24495. Epub 2020 Nov 29. PMID: 33251700.1. journals2021
Valery LavergneLavergne V, Ghannoum M, Gosselin S, Goldfarb D, Nolin TD, Dargan PI, Roberts DM. Assessing the effect of extracorporeal treatments for lithium poisoning. Br J Clin Pharmacol. 2021 Jan;87(1):214-215. doi: 10.1111/bcp.14367. Epub 2020 Jun 5. PMID: 32501620.1. journals2021
Veronica Hirsch-ReinshagenHoiland RL, Ainslie PN, Wellington CL, Cooper J, Stukas S, Thiara S, Foster D, Fergusson NA, Conway EM, Menon DK, Gooderham P, Hirsch-Reinshagen V, Griesdale DE, Sekhon MS. Brain Hypoxia Is Associated With Neuroglial Injury in Humans Post-Cardiac Arrest. Circ Res. 2021 Aug 20;129(5):583-597. doi: 10.1161/CIRCRESAHA.121.319157. Epub 2021 Jul 21. PMID: 34287000; PMCID: PMC8376277.1. journals2021
Veronica Hirsch-ReinshagenChatterjee A, Hirsch-Reinshagen V, Moussavi SA, Ducharme B, Mackenzie IR, Hsiung GR. Clinico-pathological comparison of patients with autopsy-confirmed Alzheimer's disease, dementia with Lewy bodies, and mixed pathology. Alzheimers Dement (Amst). 2021 May 18;13(1):e12189. doi: 10.1002/dad2.12189. PMID: 34027019; PMCID: PMC8129858.1. journals2021
Victor LeungLi L, Lowe CF, Ritchie G, Stefanovic A, Champagne S, Romney MG, Leung V, Matic N. SARS-CoV-2 molecular testing for the diagnosis of COVID-19: One test does not fit all. J Med Virol 2021 Feb;93(2):712-713. doi: 10.1002/jmv.26532. Epub 2020 Sep 30.1. journals2021
Victor LeungKinloch NN, Ritchie G, Dong W, Cobarrubias KD, Sudderuddin H, Lawson T, Matic N, Montaner JSG, Leung V, Romney MG, Lowe CF, Brumme CJ, Brumme ZL. SARS-CoV-2 RNA quantification using droplet digital RT-PCR  J Mol Diagn. 2021 May 29:S1525-1578(21)00136-7. doi: 10.1016/j.jmoldx.2021.04.014. Online ahead of print.1. journals2021
Victor LeungAddleman S, Leung V, Asadi L, Sharkawy A, McDonald J. Mitigating airborne transmission of SARS-CoV-2. CMAJ. 2021 Jun 8:cmaj.210830. doi: 10.1503/cmaj.210830. Online ahead of print.1. journals2021
Victor LeungMatic N, Lawson T, Ritchie G, Stefanovic A, Leung V, Champagne S, Romney MG, Lowe CF. Automated molecular testing of saliva for SARS-CoV-2 detection. Diagn Microbiol Infect Dis 2021 May;100(1):115324 doi: 10.1016/j.diagmicrobio.2021.115324. Epub 2021 Jan 23.1. journals2021
Victor LeungMatic N, Lowe CF, Ritchie G, Stefanovic A, Lawson T, Jang W, Young M, Dong W, Brumme ZL, Brumme CJ, Leung V, Romney MG. Rapid Detection of SARS-CoV-2 Variants of Concern, Including B.1.1.28/P.1, British Columbia, Canada. Emerg Infect Dis 2021 Jun;27(6):1673-1676.doi: 10.3201/eid2706.210532. Epub 2021 Mar 30.1. journals2021
Victor LeungLowe CF., Kiaii M., Aparicio L., Chinybaeva L., Coughlin S., Sekirov I., Morshed M., Leung V.  Risk following a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) exposure from a nocturnal hemodialysis patient utilizing continuous positive airway pressure (CPAP). Infect Control Hosp Epidemiol. 2021 Apr;42(4):491-492. doi: 10.1017/ice.2020.291. Epub 2020 Jun 11.1. journals2021
Victor LingJonathan A Shep, Renxue Wang, Jianshe Wang, Victor Ling (2021) The protective role of hydrophilic tetrahydroxylated bile acids (THBA). Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids Volume 1866, Issue 7, July 2021, 1589251. journals2021
Victor LingTeng Liu, Jing Zhao, Xiao-Jun Zhu, Jia-Yan Feng, Yi Lu, Jonathan A. Sheps, Ren-Xue Wang, Jun Han, Victor Ling, Jian-She Wang (2021)  Neonatal Dubin-Johnson Syndrome and Its Differentiation from Biliary Atresia. Journal of Clinical and Translational Hepatology ( in press)1. journals2021
Vijay GadkarKinshella MW, Tilley P, Al-Rawahi GN, Srigley JA, Kayda I, Canes M, McLennan M, Bone JN, Dittrick M, Gadkar VJ, Hoang LMN, Goldfarb DM. Evaluation of observed and unobserved self-collection of saline gargle samples for the detection of SARS-CoV-2 in outpatients. Diagn Microbiol Infect Dis. 2022 Feb;102(2):115566. doi: 10.1016/j.diagmicrobio.2021.115566. Epub 2021 Oct 2. PMID: 34781164; PMCID: PMC8486683.1. journals2021
Vijay GadkarGadkar VJ, Goldfarb DM, Young V, Watson N, Al-Rawahi GN, Srigley JA, Tilley P. Development and validation of a new triplex real-time quantitative reverse Transcriptase-PCR assay for the clinical detection of SARS-CoV-2. Mol Cell Probes. 2021 Aug;58:101744. doi: 10.1016/j.mcp.2021.101744. Epub 2021 Jun 4. PMID: 34089805; PMCID: PMC8176879.1. journals2021
Vijay GadkarGoldfarb DM, Tilley P, Al-Rawahi GN, Srigley JA, Ford G, Pedersen H, Pabbi A, Hannam-Clark S, Charles M, Dittrick M, Gadkar VJ, Pernica JM, Hoang LMN. Self-Collected Saline Gargle Samples as an Alternative to Health Care Worker-Collected Nasopharyngeal Swabs for COVID-19 Diagnosis in Outpatients. J Clin Microbiol. 2021 Mar 19;59(4):e02427-20. doi: 10.1128/JCM.02427-20. PMID: 33514627; PMCID: PMC8092743.1. journals2021
Vincenzo GiambraProtein Tyrosine Kinases: Their Roles and Their Targeting in Leukemia. K Bhanumathy K, Balagopal A, Vizeacoumar FS, Vizeacoumar FJ, Freywald A, Giambra V. Cancers (Basel). 2021 Jan 7;13(2):184. doi: 10.3390/cancers13020184. PMID: 334302921. journals2021
Vincenzo GiambraTargeting leukemia-initiating cells in acute lymphoblastic leukemia (ALL). Tamiro F, Weng AP, Giambra V. Cancer Res. 2021 Jan 7:canres.2571.2020. doi: 10.1158/0008-5472.CAN-20-2571. Online ahead of print. PMID: 334141701. journals2021
Wan LamMelese ES, Franks SE, Cederberg RA, Harbourne BT, Shi R, Wadsworth BJ, Collier JL, Halvorsen EC, Johnson F, Luu J, Oh MH, Lam V, Krystal G, Hoover SB, Raffeld M, Simpson RM, Unni AM, Lam WL, Lam S, Abraham N, Bennewith KL, Lockwood WW (2021) CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development. OncoImmunology 11. In press. [Published online: 30 Dec 2021] CA1. journals2021
Wan LamCohn DE, Barros-Filho MC, Minatel BC, Pewarchuk ME, Marshall EA, Vucic EA, Sage AP, Telkar N, Stewart GL, Jurisica I, Reis PP, Robinson WP, Lam WL. (2021). Reactivation of multiple fetal miRNAs in lung adenocarcinoma. Cancers (Basel). 13(11): 2686, 1-14. SA1. journals2021
Wan LamLebovitz C, Wretham N, Osooly M, Milne K, Dash T, Thornton S, Tessier-Cloutier B, Sathiyaseelan P, Bortnik S, Go NE, Halvorsen E, Cederberg RA, Chow N, Dos Santos N, Bennewith KL, Nelson BH, Bally MB, Lam WL, Gorski SM. (2021). Loss of Parkinson's susceptibility gene LRRK2 promotes carcinogen induced lung tumorigenesis. Scientific Reports 11(1) 2097, 1-14. CA1. journals2021
Wan LamReis PP, Lam WL, Elgui de Oliveira D. (2021). Human and oncoviral non-coding RNAs as modulators of cancer aggressiveness and disease progression. Frontiers in Oncology 10: 641725. CA1. journals2021
Wan LamMartinez VD, Cohn DE, Telkar N, Minatel BC, Pewarchuk ME, Marshall EA, Price EM, Robinson WP, Lam WL. (2021). Profiling the small non-coding RNA transcriptome of the human placenta. Scientific Data 28(1):166, 1-8. SA1. journals2021
Wan LamMartinez VD, Lam WL. (2021). Health effects associated with pre- and perinatal exposure to arsenic. Frontiers in Genetics 12: 664717, 1-10. SA1. journals2021
Wan LamStewart GL, Sage AP, Enfield KS, Marshall EA, Cohn DE, Lam WL. (2021). Deregulation of a cis-acting lncRNA in non-small cell lung cancer may control HMGA1 expression. Frontiers in Genetics 11:615378, 1-9.5. SA1. journals2021
Wan LamMartinez VD, Sage AP, Minatel BC, Marshall EA, Price EM, Becker-Santos DD, Robinson WP, Lam WL. (2021). Human placental piwi-interacting RNA transcriptome is characterized by expression from the DLK1-DIO3 imprinted region. Scientific Reports 11(1): 14981, 1-9. SA1. journals2021
Wan LamMarshall EA, Telkar N, Lam WL. (2021). Functional role of the cancer microbiome in the solid tumour niche. Current Research in Immunology 2:1-6. SA1. journals2021
Wan LamHernández-Cordero AI, Yang CX, Yang J, Horvath S, Shaipanich T, MacIsaac J, Li DTS, Kobor MS, Guillemi S, Harris M, Lam W, Lam S, Obeidat M, McEwen L, Lin D, Novak R, Hudson F, Klinker H, Dharan N, Montaner J, Man SFP, Kunisaki K, Sin DD, Leung JM on behalf of the INSIGHT START Pulmonary and Genomic Substudy Groups (2021) The epigenetic aging biomarker grimage is associated with lung function in both the airway and blood of patients living with HIV. Submitted. CA1. journals2021
Wan LamFraser M, Ghiam AF, Zafarana G, Lalonde E, Sykes J, Lam WL, Meng A, Milosevic M, van der Kwast T, Boutros PC,. Bristow RG (2021) Genomic instability at common fragile sites predicts metastasis and overall survival in localized, non-indolent prostate cancer. Clinical Cancer Research. Submitted. CA1. journals2021
Wan LamMinatel BC, Cohn DE, Pewarchuk ME, Barros-Filho MC, Sage AP, Stewart GL, Marshall EA, Telkar N, Martinez VD, Reis PP, Robinson WP, Lam WL (2021) Genetic and epigenetic mechanisms deregulate the CRL2pVHL complex in hepatocellular carcinoma. International Journal of Molecular Sciences. Under review. SA1. journals2021
William LockwoodCalder J, Luu J, Nagelberg A, Lu D, Lockwood WW (2021) Resistance to BET inhibitors in lung adenocarcinoma is mediated by caesin kinase phosphoylation of BRD4. Oncogenesis. 10(3): 27. SA1. journals2021
William LockwoodFarnsworth D, Inoue Y, Johnson F, de Rappard-Yuswack G, Somwar R, Ladanyi M, Unni AM, Lockwood WW (2021) MEK inhibitor resistance in lung cancer is associated with addiction to sustained ERK suppression, representing a novel, therapeutically relevant vulnerability. Molecular Cancer Therapeutics. (Under Revision)
 
 
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William LockwoodMarshall EA, Vega AA, Noonan AJC, Sergio Leitao Filho F, Yang JSW, Steward GL, Johnson FD, Vucic EA, Pewarchuk ME, Nislow C, Lam S, Lockwood WW, Hallam SJ, Leung JM, Beverly LJ, Lam WL. (2021). Methionine-Producing Tumour Micro(Be) Environment Fuels Growth of Solid Tumours. Cell Reports (preprint published online at Cell Press Sneak Peak). (Under Revision)1. journals2021
William LockwoodTurgu B, Zhang F, El Naggar A, Negri G, Kogler M, Tortola L, Johnson F, Ng T, Li A, Yapp D, Lockwood WW, Daugaard M, Penninger J, Hughes C, Sorensen P (2021) HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner. Oncogene. 40(11):1988-2001.1. journals2021
William LockwoodXue Y , Morris J, Yang K , Johnson F, Fu Z, Zhu X, Witkowski L , Yasmeen A , Coatham M, Golenar T , Morin G, Monast A, Pilon V, Fiset P, Jung S, Gonzalez A, Camilleri-Broet S, Fu L , Postovit LM, Spicer J, Gotlieb W, Guiot MC, Lockwood WW, Park M, Foulkes WF, Prudent J, Huang S. (2021). SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria. Nature Communications. 12(1): 5404.1. journals2021
William LockwoodFarnsworth DA, Chen YT, de Rappard Yuswack G, Lockwood WW (2021) Emerging Molecular Dependencies of Mutant EGFR-Driven Non-Small Cell Lung Cancer. Cells. Dec 16;10(12):3553. SA1. journals2021
William LockwoodInoue Y, Nikolic A, Farnsworth D, Liu A, Ladanyi M, Somwar R, Gallo M, Lockwood WW. (2021). Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer. eLife. 10: e66524. SA1. journals2021
William LockwoodMelese ES, Franks E, Cederberg RA, Harbourne BT, Shi R, Wadsworth BJ, Collier JL, Halvorsen EC, Johnson F, Luu J, Oh MH, Lam V, Krystal G, Hoover SB, Raffeld M, Simpson RM, Unni AM, Lam WL, Lam S, Abraham N, Bennewith KL*, Lockwood WW* (2022) CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development, OncoImmunology, 11:1. *Co-Senior Author1. journals2021
Xuehai WangWang X, Nissen M, Gracias D, Chavez E, Segat GC, Kusakabe M, Simkin G, Aoki T, Nguyen ATT, Gascoyne RD, Brinkman RR, Scott DW, Steidl C, Weng AP. (2021). Single-cell profiling reveals clinically relevant evolutionary trajectories and alternate biologies in human follicular lymphoma. Nature Cancer (Under revision)1. journals2021
Yemin WangKarnezis AN, Chen SY, Chow C, Yang W, Hendricks WPD, Ramos P, Briones N, Mes-Masson AM, Bosse T, Gilks CB, Trent JM, Weissman B, Huntsman DG, Wang Y (SA). Re-assigning the histologic identities of COV434 and TOV-112D ovarian cancer cell lines. Gynecol Oncol. 2021 Feb: 160(2):568-578. doi:10.1016/j.ygyno.2020.12.004. Epub ahead of print. 2020 Dec 13PMID: 33328126.1. journals2021
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Zu-Hua GaoZhang H, Corredor ALG, Messina-Pacheco J, Li Q, Zogopoulos G, Kaddour N, Wang Y, Shi BY, Gregorieff A, Liu JL, Gao ZH. REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway. Commun Biol. 2021 Jun 7;4(1):688. doi: 10.1038/s42003-021-02193-z. PMID: 34099862; PMCID: PMC8184755.  impact factor 12.51. journals2021
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Zu-Hua GaoAbdouh M, Tabah R, Arena V, Arena M, Gao ZH, Lorico A, Arena GO. Oncosuppressor-Mutated Cell-Based Diagnostic Platform for Liquid Biopsy Diagnoses Benign Head and Neck Masses and Predicts Malignancy in Thyroid Nodules: Results from a Consecutive Cohort of Patients. Eur Thyroid J. 2021 Jul;10(4):285-294. doi: 10.1159/000516421. Epub 2021 Jun 7. PMID: 34395300; PMCID: PMC8314779.1. journals2021
Zu-Hua GaoWang YF, Cuggia A, Pacis A, Boilea JC, Marcus V, Gao ZH, Chong G, Foulkes W, Zogopoulos G. Hyperprogressive disease on immunotherapy in a Lynch syndrome patient with pancreatic cancer: a cautionary tale. Journal for Comprehensive Cancer Network 2021; 19(8):883-887. doi: 10.6004/jnccn.2021.7049,Impact factor 7.571. journals2021
Zu-Hua GaoMartinez Ramirez C, Lai J, Facciorusso A, Gao ZH. Cancer Registry Study of Malignant Hepatic Vascular Tumors: Hepatic Angiosarcomas and Hepatic Epithelioid Hemangioendotheliomas. Cancer Medicine 2021; 10(24):8883-8890. doi: 10.1002/cam4.4403.   Impact factor 3.362.1. journals2021
Zu-Hua GaoWang YF, Cuggia A, Pacis A, Boilea JC, Marcus V, Gao ZH, Chong G, Foulkes W, Zogopoulos G.  Oncology clinic-based germline genetic testing for exocrine pancreatic cancer enables timely return of results and unveils low uptake of cascade testing. Journal of Medical Genetics.2021  doi: 10.1136/jmedgenet-2021-108054.. Impact factor 4.9431. journals2021
Lucy PerroneGopolang F, Zulu-Mwamba F, Nsama D, Kruuner A, Nsofwa D, Kasvosve I, Gomo R, Motlhabane T, Chohan B, Soge O, Osterhage D, Campbell N, Noble M, Downer A, Flandin JF, Nartker A, Koehn C, Nonde LK, Shibemba A, Ndongmo CB, Steinau M, Perrone LA. Improving laboratory quality and capacity through leadership and management training: Lessons from Zambia 2016-2018. Afr J Lab Med. 2021 Apr 30;10(1):1225. doi: 10.4102/ajlm.v10i1.1225. PMID: 34007816; PMCID: PMC8111616.1. journals2021
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