PATH 375 Introduction to Human Pathology

Course Learning Outcomes

By the end of this course, students will be able to:

1. Describe cellular responses to change and injury including:
   1. Hyperplasia, hypertrophy, metaplasia, and atrophy.
   2. Intracellular accumulations (anthracosis, hemosiderosis, and lipid accumulation).
   3. Cell death including necrosis and apoptosis.
2. Explain the key components and outcomes of inflammation including:
   1. Physical signs of inflammation and cellular events in inflammation.
   2. Classification of different types of inflammation.
   3. Healing and wound repair.
3. Explain the key aspects of pathology related to the immune system including:
   1. Hypersensitivity reactions.
   2. Transfusion reactions, transplant rejection and graft versus host disease.
   3. Autoimmune diseases and immunodeficiency diseases.
4. Describe the key aspects of neoplasia including:
   1. Terminology and classification of neoplasms.
   2. Causes, clinical manifestations of, and epidemiology of cancer.
5. Describe the key aspects of developmental abnormalities including:
   1. Genetic factors and teratogens.
   2. Chromosomal abnormalities, single gene and multifactorial disorders.
   3. Prenatal diagnosis, prematurity, birth injury and sudden infant death.
6. Describe key aspects of fluid and hemodynamic disorders.
7. List and describe the pathophysiological processes underlying diseases of the major organ systems.