PATH 375 Introduction to Human Pathology

PATH 375 Introduction to Human Pathology
2024W1: Tuesday/Thursday 9:30-11:00am
Location: TBA

2024W2: Tuesday/Thursday 3:30-5:00pm
Location: TBA

A lecture-demonstration course designed to acquaint students in the allied health professions with a basic understanding of the causes, natural history, and pathophysiology of common disease processes.
Prerequisites: 6 credits each first year Biol and Chem.


Cell pathology
Inflammation, Repair and Response to Injury
Genetic and Developmental Diseases
Cardiovascular System
Fluid and Haemodynamic Disorders
Respiratory System
Haematopoietic and Lymphoid Systems
Gastrointestinal System
Liver and Biliary Tract and the Pancreas
Urinary Tract and the Male Genital System
Reproductive System and the Breast
Bones, Joints, Muscle, Skin,
Endocrine System
Central Nervous System

Exam format: both the midterm and final exam are multiple choice.

Course Learning Outcomes

By the end of this course, students will be able to:

  1. Describe cellular responses to change and injury including:
    1. Hyperplasia, hypertrophy, metaplasia, and atrophy.
    2. Intracellular accumulations (anthracosis, hemosiderosis, and lipid accumulation)
    3. Cell death including necrosis and apoptosis
  2. Explain the key components and outcomes of inflammation including:
    1. Physical signs of inflammation and cellular events in inflammation.
    2. Classification of different types of inflammation.
    3. Healing and wound repair.
  3. Explain the key aspects of pathology related to the immune system including:
    1. Hypersensitivity reactions.
    2. Transfusion reactions, transplant rejection and graft versus host disease.
    3. Autoimmune diseases and immunodeficiency diseases.
  4. Describe the key aspects of neoplasia including:
    1. Terminology and classification of neoplasms.
    2. Causes, clinical manifestations of, and epidemiology of, cancer
  5. Describe the key aspects of developmental abnormalities including:
    1. Genetic factors and teratogens.
    2. Chromosomal abnormalities, single gene and multifactorial disorders
    3. Prenatal diagnosis, prematurity, birth injury and sudden infant death
  6. Describe key aspects of fluid and hemodynamic disorders.
  7. List and describe the pathophysiological processes underlying diseases of the major organ systems.

Course Syllabus
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