Zimring, James
MD
Academic Rank(s): Professor, UBC, Department of Pathology and Laboratory Medicine | Investigator, Centre for Blood Research, UBC
Affiliation(s): Centre for Blood Research,UBC
Research and Scholarly Interests: Mechanisms of alloimmunity in transfusion and transplantation; Induction of alloantibodies by transfusion and pregnancy; Hemolytic transfusion reactions, platelet refractoriness, and fetal–maternal alloimmunity; Oxidative stress biology in red blood cells and G6PD deficiency; Pharmacotoxicology of hemolytic drugs in G6PD-deficient patients
Dr. James C. Zimring is a Professor (Partner) in the Department of Pathology and Laboratory Medicine at the University of British Columbia and an internationally recognized physician-scientist in transfusion medicine. He also serves as Chief Scientific Officer of Canadian Blood Services. Dr. Zimring obtained both his MD and PhD in Immunology at Emory University and is board-certified in Clinical Pathology with a focus on transfusion medicine. His program integrates basic and translational research, clinical insight, and extensive mentorship of graduate, postgraduate, and undergraduate trainees.
Academic Background
- MD — Emory University School of Medicine, 1999
- PhD, Immunology — Emory University, 1999
- BSc, Chemistry — Emory University, 1992
Awards and Recognition
Publications
Full list of publications may be found here.
Research Interest
Dr. Zimring’s research focuses on two primary areas.
- The first examines the mechanisms of afferent and efferent alloimmunity in the context of transfusion and transplantation, including the induction of alloantibodies through transfusion and pregnancy, hemolytic transfusion reactions, platelet refractoriness, and fetal–maternal alloimmunity.
- His second major research focus is oxidative stress biology in red blood cells, with particular emphasis on glucose-6-phosphate dehydrogenase (G6PD) deficiency and the pharmacotoxicology of drugs that induce hemolysis in G6PD-deficient individuals. This work employs both animal models and human studies and includes proteomic, metabolomic, and genome-wide association approaches to identify novel biological pathways relevant to transfusion medicine.
Current Projects In My Lab Include
Teaching Interest
Dr. Zimring has a strong commitment to education and mentorship at all levels, including graduate students, postdoctoral fellows, residents, and undergraduate researchers.