
Spence, Tara
MSc, PhD, PMP
Academic Rank(s): Clinical Assistant Professor, Pathology and Laboratory Medicine, UBC | Cytogeneticist & Molecular Geneticis; Director, Cytogenomics Laboratory, Vancouver General Hospital | Cancer Genetics and Genomics Laboratory, BC Cancer Vancouver (cross-coverage)
Affiliation(s): Vancouver General Hospita / BC Cancer
Research and Scholarly Interests:
Clinical Interests:
As a Canadian College of Medical Geneticists (CCMG) certified Cytogeneticist and Molecular Geneticist, I joined the Cytogenomics Laboratory at Vancouver General Hospital in May 2022 as the new Laboratory Director. I also support coverage in the Cancer Genetics and Genomics Laboratory at BC Cancer. I originally hail from Ontario, where I completed my MSc in Microbiology and Immunology at Queen’s University in 2009 and my PhD in 2014 from SickKids and the University of Toronto in the Department of Laboratory Medicine and Pathobiology, specializing in pediatric brain tumor research. I then went on to work as a Scientific Associate at the Department of Radiation Oncology at the Princess Margaret Cancer Centre, and then as a Senior Variant Annotation Specialist, working in the Department of Genome Diagnostics at the University Health Network. Most recently, I completed my CCMG training in Genetics and Genome Diagnostics (dual training in Cytogenetics and Molecular Genetics) at the University of Calgary. My research interests focus on test validation and variant interpretation in the context of genomic testing for somatic and inherited cancers, including approaches to employ expanded genetic testing to increase diagnostic yield and impact research potential. My recent publications have investigated methods for copy number analysis in cancer diagnostic testing, clinical implementation of circulating tumor DNA testing for lung cancer patients, clinical laboratory proficiency testing strategies for tumor molecular diagnostics, and approaches to standardization of somatic variant interpretation practices in Canadian diagnostic laboratories.
Academic Background
- PhD, Laboratory Medicine and Pathobiology, Arthur and Sonia Labatt Brain Tumour Research Centre, University of Toronto and The Hospital for Sick Children, 2014
- MSc, Microbiology and Immunology, Queen’s University, Kingston, Ontario, 2009
- BSc, Honours Biology, University of Waterloo, 2007
Awards and Recognition
Publications
Selected Publications
Research Interest
- My research interests focus on test validation and variant interpretation in the context of genomic testing for somatic and inherited cancers, including approaches to employ expanded genetic testing to increase diagnostic yield and impact research potential
Clinical Service