Nielsen, Torsten
MD/PhD FRCPC
Academic Rank(s): Professor, Department of Pathology & Laboratory Medicine, Faculty of Medicine, UBC | Director, UBC MD/PhD Program
Affiliation(s): Vancouver General Hospital and the BC Cancer Agency
Research and Scholarly Interests: Sarcoma, breast cancer, histopathology, molecular diagnostics
Clinical Interests: Musculoskeletal pathology, particularly in the diagnosis of connective tissue neoplasms and sarcomas
Professor Torsten Nielsen completed the MD/PhD program at McGill followed by a residency in Anatomical Pathology at UBC, before taking up a position as a clinician-scientist. He combines work as a musculoskeletal subspecialty pathologist with active grant-funded research programs in breast cancer and sarcomas, the common themes of which are the translation of genomic discoveries into clinically-practical new diagnostics and treatments. Among his accomplishments in sarcoma research are the development of novel diagnostic tests for synovial sarcoma, gastrointestinal stromal tumor and liposarcomas, and the identification of driver events leading to new treatments for tenosynovial giant cell tumor and epithelioid sarcoma. In breast cancer Dr. Nielsen pioneered intrinsic subtyping tests including the FDA-cleared PAM50 (Prosigna) assay, and has taken a lead role in international efforts to standardize Ki67 and immune biomarkers for implementation in hospital pathology laboratories. He is active with clinical trials groups and is the Director of UBC’s combined MD/PhD program, training a new generation of clinician-scientists.
Academic Background
- MD/PhD, McGill University. 1997
- PhD, Experimental Medicine, McGill University. 1996
- BSc, Biochemistry (1st class honours) University of British Columbia. 1991
Awards and Recognition
Publications
Research Interest
- Translational research in breast cancer – developing clinically-practical predictive biomarkers using tissue microarray and Nanostring technology
- Molecular oncology of sarcomas afflicting the AYA (adolescent and young adult) population – synovial sarcoma, myxoid liposarcoma, epithelioid sarcoma and related cancers
- Correlative science support for clinical trials in breast cancer and sarcoma, in association with the Canadian Cancer Trials Group
Current Projects In My Lab Include
Dr. Nielsen’s active projects are listed at: http://www.gpecdata.med.ubc.ca/torsten/ActiveResearch.html
Teaching Interest
Director, UBC MD/PhD program: https://mdprogram.med.ubc.ca/mdphd/directors-message/