Ng, Tony

Portrait photo of Tony Ng

Ng, Tony

MD/PhD FRCPC

Academic Rank(s): Clinical Associate Professor, Pathology and Laboratory Medicine, UBC | Staff Pathologist, Vancouver General Hospital

Affiliation(s): VGH/VCHRI

Research and Scholarly Interests: Cancer, Genetics genomics proteomics and related approaches

Clinical Interests:

Short Bio
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Dr. Tony Ng is a head and neck pathologist and sarcoma pathologist at Vancouver General Hospital, as well as a clinical associate professor in the Department of Pathology and Laboratory Medicine at the University of British Columbia.

 

Academic
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Academic Background

  • PhD, Pathology and Laboratory Medicine, The University of British Columbia. 2014
  • Residency, Anatomical Pathology, The University of British Columbia. 2012
  • MD, The University of British Columbia. 2004

Awards and Recognition

Publications

Selected Publications

  • Sweeney R.T., McClary A.C., Myers B.R., Biscocho J., Neahring L., Kwei K.A., Qu K., Gong X., Ng T., Jones C.D., Varma S., Odegaard J.I., Sugiyama T., Koyota S., Rubin B.P., Troxell M.L., Pelham R.J., Zehnder J.L., Beachy P.A., Pollack J.R., West R.B. Identification of recurrent SMO and BRAF mutations in ameloblastomas. Nat Genet. 2014 Jul;46(7):722-5.
  • Ng T. L., Leprivier G., Robertson M.D., Martin M.J., Laderoute K.R., Davicioni E., Triche T.J., Sorensen P.H. The AMPK stress response pathway mediates anoikis resistance through inhibition of mTOR and suppression of protein synthesis. Cell Death Diff. 2012 Mar; 19(3):501-10. Journal article).
  • Lange AP., Moloney G., Arino M., Ng T., McCarthy J.M., White VA, Holland S.P. Enzyme-assisted deep anterior lamellar keratoplasty-a new method of lamellar dissection-a wetlab-based pilot study. Cornea 2012 Mar 29 [Epub ahead of print] Journal article).
  • Potratz J.C., Saunders D.N., Wai D.H., Ng T.L., McKinney S.E., Carboni J.M., Gottardis M.M., Triche TJ., Jurgens H., Pollak M.N., Aparicio SA, Sorensen P.H. Synthetic Lethality Screens Reveal RPS6 and MST1 R as Modifiers of Insulinlike Growth Factor-1 Receptor Inhibitor Activity in Childhood Sarcomas. Cancer Res. 2010 Nov 1; 70(21 ):8770-81. Journal article).
  • Strauss S.J., Ng T., Mendoza-Naranjo A, Whelan J., Sorensen P.H. Understanding Micrometastatic Disease and Anoikis Resistance in Ewing Family of Tumors and Osteosarcoma. Oncologist. 2010; 15(6):627-35. Journal article).
  • Evdokimova V., Tognon C., Ng T., Sorensen P.H. Reduced proliferation and enhanced migration: two sides of the same coin? Molecular mechanisms of metastatic progression by YB-1. Cell Cycle. 2009 Sep 15;8(18):2901-6. Journal article).
  • Viswanathan S.R., Powers J.T., Einhorn W., Hoshida Y., Ng T.L., Toffanin S., O’Sullivan M., Lu J., Phillips L.A, Lockhart V.L., Shah S.P., Tanwar P.S., Mermel C.H., Beroukhim R., Azam M., Teixeira J., Meyerson M., Hughes T.P., Llovet J.M., Radich J., Mullighan C.G., Golub T.R., Sorensen P.H., Daley G.a. Lin28 promotes transformation and is associated with advanced human malignancies. Nat Genet. 2009 Jul;41 (7):843-8. Journal article).
  • Evdokimova V., Tognon C., Ng T., Ruzanov P., Melnyk N., Fink D., Sorokin A, Ovchinnikov L.P., Davicioni E., Triche T.J., Sorensen P.H. Translational activation of snail1 and other developmentally regulated transcription factors by YB-1 promotes an epithelial-mesenchymal transition. Cancer Cell. 2009 May 5;15(5):402-15. Uournal article).
  • Chuo J.Y., Dolman P.J., Ng T.L., Buffam F.v., White VA Clinical and histopathologic review of 18 explanted porous polyethylene orbital implants. Ophthalmology. 2009 Feb; 116(2):349-54. Uournal article).
  • Ng T.L., O’Sullivan M.J., Pallen C.J., Hayes M., Clarkson P.W., Winstanley M., Sorensen P.H., Nielsen T.O., Horsman D.E. Ewing Sarcoma with Novel Translocation t(2; 16) Producing an In-Frame Fusion of FUS and FEV. J Mol Diagn. 2007 Sep;9(4):459-63. Journal article).
Research
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Research Interest

Cancer

Clinical Service

Current Projects In My Lab Include

Teaching
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Teaching Interest

Teaching the head and neck surgery residents and the oral pathology residents