Associate Professor, UBC, Investigator, Michael Cuccione Childhood Cancer Research Program, BC Children’s Hospital
Dr. Philipp Lange is Canada Research Chair in Translational Proteomics of Pediatric Malignancies and Associate Professor, Departments of Pathology and Computer Science, University of British Columbia (UBC). He is also an MSFHR Scholar and Scientist in the Michael Cuccione Childhood Cancer Research Program at the BC Children’s Hospital and the BC Cancer Research Institute.
Dr. Lange’s research focuses on oncoproteoforms, proteins with cancer-specific post-translational modification, and their altered function, role in cell-cell communication and drug resistance, and their potential use as drug targets and biomarkers. His team drives the development and translation of proteomics platforms to advance molecular pathology and guide pre-clinical studies and precision treatment for kids with cancer.
Dr. Lange co-leads the multi-centre proteomics team in the Canadian Precision Oncology For Young People (PROFYLE) study and has won several awards for his advances in cancer research including the 2020 CIHR Early Career Investigator in Cancer Award and the 2016 Great Canadian Innovation Award by the Canadian Cancer Society.
Dr. Philipp Lange received his Ph.D. in Biochemistry from the Free University Berlin, Germany after earning an MSc in Molecular Biology, Microbiology and Computer Sciences from the University of Hamburg, Germany. During his Ph.D. at the Max Delbruck Centre for Molecular Medicine, Berlin, Germany he studied the molecular causes of hereditary osteopetrosis in children and patented a new drug target for the treatment of osteoporosis in women. He conducted his postdoctoral work with Dr. Christopher Overall at the Centre for Blood Research, UBC studying post-translational modification in breast cancer. http://langelab.med.ubc.ca
Free University of Berlin, PhD, Biochemistry. 2008
University of Hamburg, MSc, Molecular Biology, Microbiology and Computer science. 2004
Awards and Recognition
- Childhood cancer
- Cell signaling
- Protein function
- Post-translational protein modification
- Targeted therapeutics