Lange, Philipp

Lange, Philipp

PhD, MSc

Academic Rank(s): Associate Professord, Pathology and Laboratory Medicine, UBC | Investigator, Michael Cuccione Childhood Cancer Research Program, BC Children’s Hospital

Affiliation(s): BCCHRI

Research and Scholarly Interests: Cancer, Genetics genomics proteomics and related approaches, Informatics, Childhood cancer, Cell signaling, Proteomics, Protein function, Post-translational protein modification, Targeted therapeutics

Clinical Interests:

Short Bio

Dr. Philipp Lange is Canada Research Chair in Translational Proteogenomics of Pediatric Malignancies and Associate Professor of Pathology at the University of British Columbia (UBC). He is also a Scientist in the Michael Cuccione Childhood Cancer Research Program at the BC Children’s Hospital and the BC Cancer Research Institute.

Dr. Lange’s research focuses on precision oncology and oncoproteoforms, proteins with cancer-specific post-translational modification, their altered function, role in cell-cell communication and drug resistance, and their potential use as drug targets and biomarkers. His team drives the development and translation of proteomics platforms to advance molecular pathology and guide precision treatment for kids with cancer.

Dr. Lange provides leadership for Cancer Biology in the Canadian Pediatric Cancer Consortium ACCESS and co-leads the multi-centre proteomics team in the Canadian Precision Oncology For Young People (PROFYLE) study. He has won several awards for his advances in cancer research including the CIHR Early Career Investigator in Cancer Award and the Great Canadian Innovation Award by the Canadian Cancer Society.

Dr. Philipp Lange received his PhD in Biochemistry from the Free University Berlin, Germany after earning an MSc in Molecular Biology, Microbiology and Computer Sciences from the University of Hamburg, Germany. During his PhD with Dr. Dr. Thomas Jentsch at the Max Delbruck Centre for Molecular Medicine, Berlin, Germany he studied the molecular causes of hereditary osteopetrosis in children and patented a new drug target for the treatment of osteoporosis in adults. He conducted his postdoctoral work with Dr. Christopher Overall at the Centre for Blood Research, UBC developing computational and proteomics approaches to study post-translational modification in cancer.



Academic Background

  • Free University of Berlin, PhD, Biochemistry. 2008
  • University of Hamburg, MSc, Molecular Biology, Microbiology and Computer science.  2004

Awards and Recognition


Selected Publications


Research Interest

  • Childhood cancer
  • Cell signaling
  • Proteomics
  • Protein function
  • Post-translational protein modification
  • Targeted therapeutics

Clinical Service

Current Projects In My Lab Include


Teaching Interest