Academic Rank:
Clinical Professor, UBC
Institute for Heart+Lung Health
Affiliation(s):
Short Bio:

Dr. John English qualified in medicine at the University of Calgary in 1984 and obtained his Fellowship in Anatomical Pathology from the University of Western Ontario in 1990. He has since worked at the Vancouver General Hospital, in the Division of Anatomical Pathology, for a time as Division Head.

Dr. English entered practise as a cardiovascular pathologist but, to fill an important clinical demand, became involved in the pulmonary pathology service in 1995. He is currently Consultant Pathologist and Discipline Lead, Cardiothoracic Pathology, VGH, Associate Member of the Division of Respiratory Medicine, UBC and recently appointed as Clinical Professor of Pathology.

Dr. English is active in teaching at all levels of undergraduate and post-graduate medicine and has given courses at national meetings. His research interests include the molecular basis of lung cancer, interstitial lung disease and radiological-pathological correlation in thoracic medicine.

Academic background

  • MD, University of Calgary. 1984
  • BSc(Hon), University of Western Ontario, Biology. 1978

 

Professional Qualifications

  • FRCP Certificate in Anatomic Pathology – L.M.C.C., Ontario. 1990
  • Residency training, University of Western Ontario, Department of Pathology (Anatomical Pathology). 1985-1990
  • Internship – Surgery , University of Western Ontario (Victoria Hospital/University Hospital). 1984-1985
  • MSc Program – Anatomy (withdrew to enter medicine), University of Calgary. 1978-1981
  • Medical License – Licentiate of the Medical Council of Canada (LMCC)
  • Medical License – College of Physicians and Surgeons of British Columbia

Publications

  • Ishii T, Abboud RT, Wallace AM, English JC, Coxson HO, Finley RJ, Shumansky K, Paré PD, Sandford AJ. Alveolar macrophage proteinase/antiproteinase expression and lung function/emphysema. ERJ (2014); 43:82-91.
  • Wallace AM, Loy LB, Abboud RT, D’Armiento JM, Coxson HO, Muller NL, Kalloger S, Li X, Elliott WM, English JC, Finley RJ, Paré PD. Expression of matrix metalloproteinase-1 in alveolar macrophages, type II pneumocytes, and airways in smokers: relationship to lung function and emphysema. Lung (2014); DOI 10.1007/s00408-014-9585-6.
  • Cressman S, Lam S, Tammemagi MC, Evans WK, Leighl NB, Regier DA, Bolbocean C, Shepherd FA, Tsao M-S, Manos D, Liu G, Atkar-Khattra S, Cromwell I, Johnson MR, Mayo JR, McWilliams A, Couture C, English JC, Goffin J, Hwang DM, Puksa S, Roberts H, Tremblay A, MacEachern P, Burrowes P, Bhatia R, Finley RJ, Goss GD, Nicholas G, Seely JM, Sekhon HS, Yee J, Amjadi K, Cutz J-C, Ionescu DN, Yasufuku K, Martel S, Soghrati K, Sin DD, Tan WC, Urbanski S, Xu Z, Peacock SJ. Resource utilization and costs durin 2014
  • Lee AMD, Kirby M, Ohtani K, Candido T, Shalansky R, MacAulay C, English J, Finley R, Lam S, Coxson H, Lane P. Validation of airway wall measurements by optical coherence tomography in porcine airways. PloS One 2014; 9(6) e10145. doi:10.1371/journal.pone.0100145.
  • Finley RJ, ….Preoperative CT-Guided Microcoil Localization of Small Peripheral Pulmonary Nodules: A Prospective Randomized Controlled Trial. J Thorac Cardiovasc Surg 2014; in press.
  • Gleeson T, Thiessen R, Hannigan A, English JC, Müller NL, Mayo JR. Pulmonary Hamartomas: CT Pixel Analysis for Fat Attenuation using Radiologic-Pathologic correlation. JMIRO 2013 (in press) Article first published online: 4 JUN 2013 | DOI: 10.1111/1754-9485.12083.
  • Wright AJ, Steiner T, Bilawich A-M, English JC, Ryan CF. Pulmonary mucormycosis in a patient with Crohn disease on immunosuppressive medications including infliximab. (2013) Can J Infect Dis Med Microbiol 24: 67-68.
  • McWilliams A, Tammemagi MC, Mayo JR, Roberts H, Liu G, Soghrati K, Yasufuku K, Martel S, Laberge F, Gingras M, Atkar-Khattra S, Berg CD, Evans K, Finley R, Yee J, English J, Nasute P, Goffin J, Puksa S, Stewart L, Tsai S, Johnston MR, Manos D, Nicholas G, Goss GD, Seely JM, Amjadi K, Tremblay A, Burrowes P, MacEachern P, Bhatia R, Tsao M-S, Lam S. Probability of cancer in pulmonary nodules detected on first screening CT. (2013) N Engl J Med 369: 910-919
  • Wilson IM, Vucic EA, Enfield KSS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, Yee J, English JC, Buys TPH, Selamat SA, Laird-Offringa I-A, Liu P, Anderson M, You M, Tsao M-S, Brown CJ, Bennewith KL, MacAulay CE, Karsan A, Gazdar AF, Lam S, Lam WL. EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk. Oncogene (2013) doi:10.1038/o
  • Dong X, Lin D, Low C, Vucic EA, English JC, Yee J, Murray N, Lam WL, Ling V, Lam S, Gout PW, Wang Y. Elevated Expression of BIRC6 Protein in Non-Small-Cell Lung Cancers is Associated with Cancer Recurrence and Chemoresistance. J Thorac Oncol 2013; 8:161-170. DOI:10.1097/JTO.0b013e31827d5237.

Research Interest

  • Ischemia – reperfusion injury in acute myocardial ischemia
  • Ischemia – reperfusion injury in lung transplantation
  • Tumour angiogenesis
  • Molecular biology of early lung cancer development
  • CT scan/pathology correlation of airway dimensions

Teaching Interest

  • Cardiovascular pathology consultant (surgical and autopsy pathology at Vancouver hospital and Health Sciences Centre; intraprovincial cardiovascular consultation).
    Principal interests: heart transplantation, atherosclerotic heart disease and myocardial ischemia, cardiomyopathies.
  • Pulmonary pathology – principal liaison between Anatomical Pathology and Clinical Pulmonary Medicine and Surgery; in charge of organizing weekly academic clinical-pathological conference with Pulmonary Medicine/Surgery/Radiology services.
    Principal interests: pulmonary transplantation, general pulmonary pathology.
  • Director – Electron Microscopy Unit, Divison of Anatomical Pathology, Department of Pathology and Laboratory Medicine, Vancouver Hospital and Health Sciences Centre.