Academic Rank:
Professor, UBC
Member, VCHRI
Institute for Heart+Lung Health
Affiliation(s):

Academic background

  • FRCP(C) – Anatomical Pathology. 1978
  • MD, University of Alberta. 1974
  • BSc, University of Alberta. 1972

Publications

  • Hackett TL, Shaheen F, Zhou S, Wright JL, Churg A. Fibroblast STAT 4 drives cigarette smoke induced airway fibrosis. Am J Respir Cell Mol Biol 2014;
  • Zhou S, Wright JL, Liu J, Sin DD, Churg A. Aging does not enhance experimental cigarette smoke induced COPD in the mouse.   PLOS 1 2013 8(8) e71410 Epub Aug 2 2013.
  • Wright JL, Churg A. Pathological findings in fatal and non-fatal asthma. Academic Forensic Pathol 2013.
  • Hui P, Mattman A, Wilcox PG, Wright JL, Sin DD. Immunoglobulin G4-related lung disease: A disease with many different faces. Can Respir J 2013; 20: 335-338.
  • Preobrazhenska O, Wright JL, Churg A. Regional heterogeneity in murine lung fibroblasts from normal mice or mice exposed once to cigarette smoke. PLoS One. 2012;7(6):e39761.
  • Yoon HI, Li Y, Man SF, Tashkin D, Wise RA, Connett JE, Anthonisen NA, Churg A, Wright JL, Sin DD. The complex relationship of serum adiponectin to COPD outcomes COPD and adiponectin. Chest. 2012 Oct;142(4):893-99.
  • Churg A, Marshall CV, Sin DD, Bolton S, Zhou S, Thain K, Cadogan EB, Maltby J, Soars MG, Mallinder PR, Wright JL. Late intervention with a myeloperoxidase inhibitor stops progression of experimental chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2012 Jan 1;185(1):34-43.
  • Churg A, Sin DD, Wright JL. Everything prevents emphysema: are animal models of cigarette smoke-induced chronic obstructive pulmonary disease any use? Am J Respir Cell Mol Biol. 2011 Dec;45(6):1111-5.
  • Wright JL, Zhou S, Preobrazhenska O, Marshall C, Sin DD, Laher I, Golbidi S, Churg AM. Statin Reverses Smoke-induced Pulmonary Hypertension and Prevents Emphysema but Not Airway Remodeling. Am J Respir Crit Care Med. 2011 Jan 1;183(1):50-8.
  • Wright JL, Churg A. Animal models of cigarette smoke-induced chronic obstructive pulmonary disease. Expert Rev Respir Med. 2010 Dec;4(6):723-34.
  • Churg A, Wright JL, Tazelaar HD. Acute exacerbations of fibrotic interstitial lung disease. Histopathology. 2010 Sep 21. doi: 10.1111/j.1365-2559.2010.03650.x.
  • Tazelaar HD, Wright JL, Churg A. Desquamative interstitial pneumonia. Histopathology. 2010 Sep 21. doi: 10.1111/j.1365-2559.2010.03649.x.
  • Wright JL, Tazelaar HD, Churg A. Fibrosis with emphysema. Histopathology. 2010 Sep 21. doi: 10.1111/j.1365-2559.2010.03648.x.
  • Churg A, Müller NL, Wright JL. Respiratory bronchiolitis/interstitial lung disease: fibrosis, pulmonary function, and evolving concepts. Arch Pathol Lab Med. 2010 Jan;134(1):27-32. Review.
  • Churg A, Zhou S, Wang X, Wang R, Wright JL. The role of interleukin-1beta in murine cigarette smoke-induced emphysema and small airway remodeling. Am J Respir Cell Mol Biol. 2009 Apr;40(4):482-90.
  • Churg A, Zhou S, Preobrazhenska O, Tai H, Wang R, Wright JL. Expression of profibrotic mediators in small airways versus parenchyma after cigarette smoke exposure. Am J Respir Cell Mol Biol. 2009 Mar;40(3):268-76.
  • Lewis EC, Mizrahi M, Toledano M, Defelice N, Wright JL, Churg A, Shapiro L, Dinarello CA. alpha1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16236-41.
  • Wright JL, Cosio M, Churg A. Animal models of chronic obstructive pulmonary disease. Am J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L1-15.
  • Wright JL, Churg A. Animal models of COPD: Barriers, successes, and challenges. Pulm Pharmacol Ther. 2008 Oct;21(5):696-8.
  • Wright JL, Postma DS, Kerstjens HA, Timens W, Whittaker P, Churg A. Airway remodeling in the smoke exposed guinea pig model. Inhal Toxicol. 2007 Sep;19(11):915-23.
Primary Research Area
Cardiovascular and Pulmonary
Secondary Research Area
Clinical or Pathological autopsies

Research Interest

  • Role of inflammation in the pathogenesis of chronic obstructive pulmonary disease.
  • Airways disease in association with mineral dusts and fumes.
  • Pulmonary vascular disease as a consequence of cigarette smoking
  • Respiratory