Cytology Series by Dr. Nguyen

 

Books by: Gia-Khanh Nguyen


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Tumors arising from the head and neck are numerous and have complicated and diversified histopathologic features. Cytodiagnosis of those neoplasms by fine needle aspiration is challenging and compounded with diagnostic pitfalls. However, with a representative cell sample and a careful evaluation of different cellular and non-cellular components, a correct diagnosis may be safely made in the majority of cases.

This monograph is written for practicing pathologists in community hospitals, pathology residents and cytotechnologists who are interested in acquiring a basic knowledge in diagnostic cytology of head and neck tumors. It consists of four chapters describing the cytologic manifestations of important tumors of the thyroid, parathyroid, salivary glands, lymph nodes, soft tissues and brain… The text is concise and illustrations are abundant.

For most tumors cytologic and histologic images are presented side by side for cytohistologic correlation. Immunohistochemical features of commonly encountered neoplasms that are important for tumor typing and differential diagnosis are stressed.

For improvement of the future editions of the monograph, constructive comments and
suggestions from the reader will be highly appreciated.

Gia-Khanh Nguyen, MD, FRCPC Professor Emeritus Department of Laboratory Medicine & Pathology University of Alberta Edmonton, Alberta, Canada

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Over the last 50 years the use of cytology in the diagnosis of breast abnormalities has waxed and waned. In areas of the world where medical litigation is rife, the enthusiasm for the use of fine needle aspiration (FNA) cytology for investigating breast lesions has been replaced largely by needle core biopsies. However, the pros and cons of these techniques are still hotly debated (Westenend 2001). There is no doubt that FNA can provide an accurate, rapid and cost effective diagnosis for most breast abnormalities. The technique is particularly applicable to cystic lesions and breast masses and has some use for the investigation of architectural abnormalities. It may provide rapid confirmation of the diagnosis of recurrent, metastatic or inflammatory breast cancer. Imprint cytology of the breast is also used as intra-operative assessment of margins of partial mastectomy procedures and to identify metastatic carcinoma in sentinel lymph node biopsies. However, in the absence of a mass lesion, calcifications are better investigated by tissue biopsy techniques. Additional cytological techniques that are of use include the analysis of nipple imprints or scrapes, nipple discharges and mammary duct brushings or lavage. The duct brushings and lavage require specialized cannulas and equipment and their use is restricted to a few major medical centres. In this monograph FNA and nipple discharge cytology of important breast lesions are presented and discussed. Relevant clinical features, imaging characteristics, and histopathological features are also included to aid comprehension of the cytological picture. The text is referenced with selected historical publications and relevant current literature. The cytological features of problematic areas are illustrated lavishly
Malcolm M. M. Hayes, MB.ChB., M Med (Anat Path), FRCPC, FRCPath Consultant Pathologist BC Cancer AgencyClinical Professor Department of Pathology University of British Columbia, Vancouver, B.C., Canada
 
Gia-Khanh Nguyen, MD, FRCPC Professor Emeritus Department of Laboratory Medicine & Pathology University of Alberta Edmonton, Alberta, Canada

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This Atlas & Text of Lung Cytology was written for practicing pathologists in community hospitals, cytotechnologists and residents in pathology who wished to have a concise and well-illustrated manual for easy consultation in their daily work. Some materials in this book were taken from the senior author’s ebook on Essentials of Lung Tumor Cytology that was published online by The David F. Hardwick Pathology Learning Centre of The University of British Columbia in 2008. The newly proposed classification of lung adenocarcinomas, classification of lung cancer in small biopsies and cytologic materials and the importance of tumor typing for molecular target therapy of lung cancer were also briefly discussed. This atlas and text should be used in conjunction with our ebook on Fluid Cytology for a more comprehensive discussion on cytopathology of pleural mesothelioma and metastatic cancers to the pleura.For improvement of the future editions of this book, comments and suggestions from the reader will be appreciated. Last but not least, we wish to thank Dr. Jason Ford, Director and Mrs. Helen Dyck, Manager of The David F. Hardwick Pathology Learning Centre for their interest and enthusiasm in publishing this book on online. A free access to the educational materials posted on the webpage of the above-mentioned centre is valuable for students with limited financial resources worldwide.
Gia-Khanh Nguyen, MD, FRCPC Brenda Smith, BSc, RT, CT (ASCP) Vancouver, BC, Canada Fall 2014

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This monograph “Essentials of Pap Smear and Breast Cytology” is prepared at the request of a large number of students in cytology who wish to have a small and concise book with numerous illustrations for easy reference during their laboratory training. Most information and illustrations in this book are extracted from the authors’ monograph entitled “Essentials of Gynecologic Cytology”, and they are rearranged according to The Bethesda System-2001. This book should be used in conjunction with the above-mentioned book on gynecologic cytology. For improving the future editions of this monograph, constructive comments from the reader will be highly appreciated.
Gia-KhanhNguyen, M.D. Surrey, British Columbia, Canada Email: khanhnguyen1730@hotmail.com Brenda Smith, BSc, RT, CT (ASCP) Vancouver, BC, Canada

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Essentials of Gynecologic Cytology”is written for practicing pathologists in private laboratories and community hospitals, residents in Pathology and cytotechnologists who want a quick review of the cytopathology of the uterus and its annexae. It consists of nine chapters and eight of them are devoted to the evaluation of the Pap smear; a test that has been regarded as the most complicated to interpret in medicine. The text in this monograph is concise and contains relevant information for cytologic interpretation of cell samples from the above-mentioned anatomic sites. Lesions commonly encountered in day-to-day practice and lesions with distinct cytologic manifestations are briefly discussed and illustrated. The cytologic materials used for the illustrations were from two Canadian institutions: University of Alberta Hospital, Edmonton, Alberta and BC Cancer Agency, Vancouver, British Columbia. The Pap smears from the former were alcohol-fixed with commercial fixatives and those from the latter were air-dried, re-hydrated and then fixed in ethanol prior to staining. Therefore, some minor differences will be observed in some cell images. Most illustrations are taken from conventional Pap smears, with a few images taken from liquid-based preparations added for comparison. Some important differences in the cytologic findings between conventional and liquid-based preparations are mentioned elsewhere in the text. A small number of histologic images are also included for cytohistologic correlations.For improvement of the future editions of this monograph, constructive comments from the reader will be highly appreciated.
Gia-Khanh Nguyen, M.D. Surrey, British Columbia, Canada Email: khanhnguyen1730@hotmail.com Brenda Smith, BSc, RT, CT (ASCP) Vancouver, BC, Canada Spring 2011

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This monograph “Essentials of Fluid Cytology” is written for practicing pathologists in community hospitals, residents in pathology and cytotechnologists who want to have a quick review of the cytopathology of serous effusions, peritoneal and pelvic washings, cerebrospinal fluid and urine in neoplastic and non-neoplastic diseases of the kidney and lower urinary tract. Cytologic manifestations of lesions commonly encountered in day-to-day practice are discussed and illustrated. In keeping with the goals of the author’s cytology monograph series, the text is concise and contains only relevant information. Immunohistochemical features of neoplasms that are important for tumor typing and differential diagnosis are stressed. And for most lesions, cytologic and histologic images are presented side by side for easy comparison. For improvement of the future editions of this monograph, comments and suggestions from the reader will be highly appreciated.
Gia-Khanh Nguyen, M.D. Surrey, British Columbia, Canada Email: khanhnguyen1730@hotmail.com Summer 2009

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The monograph “Essentials of Abdominal Fine Needle Aspiration Cytology” is written for practicing pathologists in community hospitals, residents in pathology and cytotechnologists who are interested in acquiring a basic knowledge on fine needle aspiration cytology of abdominal tumors/lesions. Commonly encountered tumors and uncommon lesions with characteristic cytologic manifestations are presented. Diagnostic criteria are presented and value and limitations of immunocytochemistry in tumor typing and differential diagnosis are stressed.